Basic Information

Gene Symbol
-
Assembly
GCA_903994105.1
Location
NW:408312-414491[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.029 1.3 9.3 5.8 1 23 223 245 223 245 0.98
2 15 1.2e-05 0.00053 19.9 0.4 1 23 251 273 251 273 0.99
3 15 0.00049 0.022 14.8 6.3 1 23 279 301 279 301 0.98
4 15 5e-05 0.0023 17.9 5.3 1 23 307 329 307 329 0.98
5 15 0.0086 0.38 10.9 2.6 1 23 335 358 335 358 0.95
6 15 0.071 3.2 8.0 1.2 3 23 366 386 364 386 0.97
7 15 0.00022 0.0097 15.9 5.1 1 23 392 414 392 414 0.97
8 15 0.002 0.089 12.9 2.5 1 23 420 442 420 442 0.98
9 15 0.00036 0.016 15.2 5.1 1 23 448 470 448 470 0.98
10 15 2.2e-05 0.00097 19.1 0.3 1 23 476 498 476 498 0.98
11 15 0.00079 0.035 14.2 7.3 1 23 504 526 504 526 0.98
12 15 4.4e-05 0.002 18.1 1.3 1 23 532 554 532 554 0.98
13 15 3.5e-05 0.0016 18.4 0.7 1 23 560 582 560 582 0.99
14 15 0.00053 0.024 14.7 7.9 1 23 589 611 589 611 0.97
15 15 0.00016 0.007 16.4 4.5 1 23 617 639 617 639 0.98

Sequence Information

Coding Sequence
ATGGATCAGCCAGAAGCAAAACACACGTCCATAGCACAACTCATCACTCCAAAAGACGAAATTTCAAGGGCTGTGTCGAGTATGAAATGTATGGAGTATCCGCTGGACAACAAACCCAAGGTTAGTCACACGGTATTCATAAATTGTGAAATAACAAAATCGGACCCAGAATCAGGATTCGACAAGGAATTCACCATTCTTGCATCCCATCCtgtgaaaattgagaaagaTCCTTTGTGTCAAGGATCTCCTTCACCAGATCAACCAGAGATTTGCTCCTACTCGTTCGATGCTCCAGCCGGTTTTGCCACAGAACTTAAATCCAAGGTAGACAATGAGGAGGAAAACTTGACCAATCAGTTACACACTAATTTTGAAATCAAGGATGAAATCTCTCCGCATCCAGATGAATCAGAAGTCACATTTACACAAATGAATGAGGAGATcctatcaaaaaattatattaattcaGCACCTTCTCATGTTCCATTGGTCCCTTTTGTGagactgaaaaatattgatgatgtTCCTCTTTACCAATCTCAAGTAAACCTTGCGGTGGAAGCAGAAtccaaagaaaatgaattcaatAGCGTTGGATCAAGCATGTCACCAAACAGAGGTATAATTACGGTaaggaatgaaaataatttctgtCATAAATCATACAAGTGCAGCTTTTGCTCCGCATGTTATTCATCTGATTGTGATTTAAAGCAACATATACAACAACACTTTCTTAAGAAACCGTTCAGGTGCAGTGATTGCtctgctccattttcccttaaaaGCTTATTGCAACTTCATATGCTAACGCACACGGGTAAGACGCCATTCAGTTGCAGCCATTGCACTGCTACTTTTACCTATAATTGCGAATTAAAAATACACTTACGAAAacacactggtgagaaaccattcagttgcagtcattgcccTATGTCTTTTACTCAGAAATGTACTTTGAATAAGCATTTGCTAATtcataccggtgagaaacctTTCAAGTGCAGTCATTGCGCTGATTCATTTGCCCGTAAACgtcttttaaaagctcattCGCTCAAGAATCACAATGGTGAAAAACCATTTGGTTGCAATCTTTGCTCTGCTACTTTTCTCTATGAATACGAATTGAAAAAACATTTCCGGAAacataccggtgagaaaccattcaattGTTGTCATTGCCCTGAgtcttttactgaaaaaaggAGTTTAAAAAAGCATTTGCTAAttcatactggtgagaaaccttTCAAATGTAGTCATTGCGCTGATTCATTTGCCAGTAAATATCTTTTAAGAACTCATTTGCTGAATCAcaccggtgagaaaccattcagttgcagtctcTGCTCTTccactttctttgaaaaatcccaTCTGAAAACACACATGCGGTCTCATTCTGGTGAGAGACCATTCAGATGCAGTCATTGCCCAGCATCCTTTGTTCTATCGGGTGCTTTAAAAGTCCATCTGCGAATtcacactggtgagaaaccattcagttgcagtcattgttCTGCCTGTTTTTCCCACAAATCCGTACTGGTTAATCATTTGCGAAGACAcaccggtgagaaaccattcatttGTAGCAAGTGCCCTCGCACTTTTAACCAAAGAACCATTTTAAGGGTTCATATGCGGTCGCACACCGGTGAGAAACCATACAAATGTAGTCATTGTCCCGCCTCATATTCTGTAAAAGCCAATGTATCACTTCACATGCGAATACACACCGGTGAGAATGGGCCGTTCAGGTGCGATCATTGTTCTGCATCTTTTTCACAGAAGAGACATTTAAGCCGACACTTGCACTTACATGCTGGCGGGGAACCATTCAGCTGCGGTCATTGCTCAGCCACCTTcaccaaaaaaaccaaattaaggAAGCATATCCTGAAGCACTCTATATAA
Protein Sequence
MDQPEAKHTSIAQLITPKDEISRAVSSMKCMEYPLDNKPKVSHTVFINCEITKSDPESGFDKEFTILASHPVKIEKDPLCQGSPSPDQPEICSYSFDAPAGFATELKSKVDNEEENLTNQLHTNFEIKDEISPHPDESEVTFTQMNEEILSKNYINSAPSHVPLVPFVRLKNIDDVPLYQSQVNLAVEAESKENEFNSVGSSMSPNRGIITVRNENNFCHKSYKCSFCSACYSSDCDLKQHIQQHFLKKPFRCSDCSAPFSLKSLLQLHMLTHTGKTPFSCSHCTATFTYNCELKIHLRKHTGEKPFSCSHCPMSFTQKCTLNKHLLIHTGEKPFKCSHCADSFARKRLLKAHSLKNHNGEKPFGCNLCSATFLYEYELKKHFRKHTGEKPFNCCHCPESFTEKRSLKKHLLIHTGEKPFKCSHCADSFASKYLLRTHLLNHTGEKPFSCSLCSSTFFEKSHLKTHMRSHSGERPFRCSHCPASFVLSGALKVHLRIHTGEKPFSCSHCSACFSHKSVLVNHLRRHTGEKPFICSKCPRTFNQRTILRVHMRSHTGEKPYKCSHCPASYSVKANVSLHMRIHTGENGPFRCDHCSASFSQKRHLSRHLHLHAGGEPFSCGHCSATFTKKTKLRKHILKHSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-