Basic Information

Gene Symbol
Dcaf11
Assembly
GCA_000775305.1
Location
Belgica.362:24773-30005[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.29 12 5.9 3.6 3 23 580 601 579 601 0.93
2 13 0.012 0.48 10.3 1.8 1 23 607 630 607 630 0.93
3 13 2.5e-05 0.001 18.7 1.1 1 23 636 660 636 660 0.98
4 13 0.14 5.6 6.9 0.6 1 23 665 688 665 688 0.96
5 13 7.6e-05 0.0031 17.2 0.9 1 23 699 722 699 722 0.96
6 13 5.5e-05 0.0023 17.6 4.9 1 23 753 775 753 775 0.98
7 13 4.1e-05 0.0017 18.0 7.2 3 23 933 954 932 954 0.96
8 13 0.0047 0.19 11.6 0.4 2 23 962 983 961 983 0.96
9 13 0.00018 0.0073 16.0 0.3 1 23 989 1012 989 1012 0.92
10 13 0.00028 0.011 15.4 5.8 1 23 1020 1042 1020 1042 0.99
11 13 3.4e-05 0.0014 18.3 3.4 1 23 1079 1101 1079 1101 0.97
12 13 1.3e-06 5.4e-05 22.7 1.4 3 23 1111 1131 1109 1131 0.97
13 13 0.051 2.1 8.3 0.3 6 22 1140 1156 1139 1156 0.95

Sequence Information

Coding Sequence
TTGGTTTATGGCCAGAGCGAGCGTTTTATGGGCAATTATTTCTCATCACTGAACATGTCGGACATCGAAGACAATTCCGTCGACCTACCGGACGCACTGAGTGACAGCGACGATGAAGActtgtttcaaaatatttcggaGCACAACTCCGGCGATCTATCCGAGCATTATCTTGTGATCATTTTGAGGCAGCTAATTGATAGTGGAGAGATCCACCTCTTGTCGCACAACCAAACCCGAAATGGGCAACTTCCTAAGATCACTAAAGGTCCAAACATGGAGAAACTGAAGGAGAGTCCACTGTACAATCAAACCAAGTGCGCATCCGGTTTCGGCGACAAAGTCAACGAGGAAGCCGACGCCAAGTGGTCGCTGGTGGACCTAATCAAGAATCGAGAGCGCGGGGGATCCTTCATGCGCCGCGACCGAtgcaaaatcaacaatttgtaCTTGCCGAACCAAGTCGAACGTCAGCTAGTGCGACTCGACTCGAAAATCTTCTGCGGCAGCTTTACTAAAGACGGAAACAACTTCGTAACGGGCAGTCAGGACCAGGAGATCAGAATTTTCGACTCGTCGACGTCCAACTACAAAGAGATAAATCATATTACGGCTAAACATGTTTCGTGGACAATTCTGGACACCGCCTTCTCACCTTGCTCTAATTACTTGGCGTATTCTTCATGGGCGGACTGCTTACACATTTGCCCACTGAACGGCACCGAAGAAGACATTAGATGCTTGAGTCTGAACACAAATGTGAACAGATTCGGCGCATTCTCGCTGGCATTTTCCAACAACGGCAAGGAAATCATTTCCGGTGGATCCGACGCCAGCGTTTACATCTTTGACCGAGAGCTCAACGAGCGAACGTTGCGAATTCCTGTGAGAAACGACGGACAAGTGACGGACGTGAACTGCGTCGGATTCGTCGACGAGTCTTCACATTTGTTCTACTCCGGAAGTGACGACGCATGCATTCGAGTGTGGGACCGACGATGCCTCAACGAGAATGATCCGGACGCGTCAGGAATTTTGTTGGGACACATTGACGGCATCACGTACATCGACTCTAAGAATGATGGTCGCTTCTTATTATCCAACTCAAAAGACCAGTCGCTCAAGTTGTGGGACATGCGCAAGTTCTCACCAAAAGAAGCCGAAGCAAACATTAAACCGCTGCTGAACACAAGAAATTGGGATTATCGATGGGACACTGTGCCGAAAAGCTacTACAACGTGACCAAACCAGTAGAAGGTGACACCTCAATTGTAACATTCAAAGGTCACCGCGTGCAGAAAAGCTTGATTCGTGCGAAGTTCTCACCAGCAGCGTCGACCGGCCAACGCTACATCTACACAGGATGTTCAACTGGCCGATTGATCATCTACGACATTTTGACTGGAAAGATGGTGAACGGCGGACTTGAAGGACACAAAGACATCGTTCGCGATGTCAGCTGGCATCCAAgacgaaatgaaattctcaCCAGCTCCTGGGACTACACAGTGAACATTAACACATTTCAAGACAAATCGACCGAGAAGAAGCGATCGCGATCCCAGTTCATGCCCTCTGACTTCGACAGTGATTTGATGGACGTGGCGCCGCCTCTGAGACGTTCGCGCAGAATTGCGCAGCGACTGGCTGGTGCATCGACGTCACGACGAAAAATGACATCTACAGCATTTGAACAAGTCGTTCTCAGTGAGAAGAAGCGCACTAGCAGCCCCATTTGCGAATCTTGCGGCAAGGAGTTCTCCAACGTTCACACACTGAATTGTCACCGGAAGCAAGTGCACGAAGGTATCAAGAACTTCCAGTGCTCGATTTGCAGTGCAAAATTCACGACGAGATACAAAACGATGCGACACTTCCAAGCCGTCCACTCAGAACTGCGAAACTACACTTGCGACTATGAGCAATGTGGAAGCACCTTCAAGACTAGCGACATGTTGAGCAAGCACCAAAGAATTCACTTCCCCGGTCCGTACAAGTGCGATGCGTGCCTCGAAGTCTTCAAGTACAAAAGCGGCTGGGATTATCACGTTCAGAAGAAGCACCGAGATTCAGGCCTTAAGACTGTCACTATCTACAAATGTTCCGAATGTCCAAGAGAGTTCAAGACGTCAGCTGCTTAtgaaaaccacaaaaagcTGCAGCATCCCGTGCCAAGTCAACCGTTCCAACCGAAAGAGCTCAATCCGAAGTCTCGACGACAGCAAGTCAAAGTCGTGAAGAGTTCCGAAGCAGAGTTTGAGTGTCACTACTGCCACAAGCGATATAAGTCGAAGGCGAACTTTATTGTTCATCTGGCGTCgcatgaaaatgaagaagaaatgcaaGACTACGATTTCATCATCAAGGAACCAGAGACACAAGTTGAACTCGACGAGACAGAGCAGCatctcgaagaagaagaagaagaagttcatgAAAGTTTAGATGAATTCGCTGGTGACAATCTGCTGAAAGGTGTCGATGAAGATTTGGtgacaattttcaagtttgaaactgAGAGATTTGTTGACGGACCCGAGAGTTTTTCAAACACTGAGTTGGACAACGAGTTGATAGCCAAGGAAACTACCGGAGAAATTGAAGGCGAAATGTATTTGTACGACGACGGTGCTGATTATATGGACGATGAAGAACAATTGGAAGAAACTGTCGAAGTTGAGCATGAATACATAGAATACTTGACCACCGACGACATCGATCAAACAACAATCCTTAATGAGACTCGCAACATGAAACCTCGGAAATCCACGCCAAACGCCAACAACACCGGGATTTGCGATGAGtgcggaaaatatttcaagcacaGCCACCATCTCAAGCGCCACATCATGCGAAAGCACCAAACTGACAGTAAAAAGTTGGAATGTGATTTTTGCGGTGCaaagtttctgctttcttACGATTTGAAGCGTCATATGATCAAGCATAGCACGAAGCGGGCATTCAAATGTAATCTCTGCGAAAACGCTTTCAAGACTGCTTCGTATCTCAAAAACCACGTCGAAGCTGTGCACACTGAGAAAACTGAGAAGAAGTTTCAATGCAAAATGTGTGAACGATCTTACGTCCACGAGCGTCACCTTGTGTACCACATGAGAAAGCACACCAACGATCTCCGGTTCAGCTGTGATTTGTGTGATCCACCGCAACTCTTTCACTACTCTGACGCCGTGAAGTGGCACAAAGTCCGACATCACGGGCAGCCCGCTCCCTTCTCTTGCACAATTTGCACCAAGAGATTTATTCACGAAAAAAGCCTGACAACGCATATGAAGGCGCATCAAGAGAACGGAACGCTCGCAGTCAACTGCCCGATCTGCGGCAAGTCAATATCGGAAAAGCGTCATTTAAAGCGCCACATACGGACTCACGACAATCACAAGTTCCACTGCCCGTGCGGATTCTCATTCAAGGAGCGACATCAACTTACAAAGCATGCGAAGACTTGTCAATTCGAATGGGAAGGCGACATCGAAGAGTTTGTGTATGAAGCTGTTGATGCCgtttga
Protein Sequence
LVYGQSERFMGNYFSSLNMSDIEDNSVDLPDALSDSDDEDLFQNISEHNSGDLSEHYLVIILRQLIDSGEIHLLSHNQTRNGQLPKITKGPNMEKLKESPLYNQTKCASGFGDKVNEEADAKWSLVDLIKNRERGGSFMRRDRCKINNLYLPNQVERQLVRLDSKIFCGSFTKDGNNFVTGSQDQEIRIFDSSTSNYKEINHITAKHVSWTILDTAFSPCSNYLAYSSWADCLHICPLNGTEEDIRCLSLNTNVNRFGAFSLAFSNNGKEIISGGSDASVYIFDRELNERTLRIPVRNDGQVTDVNCVGFVDESSHLFYSGSDDACIRVWDRRCLNENDPDASGILLGHIDGITYIDSKNDGRFLLSNSKDQSLKLWDMRKFSPKEAEANIKPLLNTRNWDYRWDTVPKSYYNVTKPVEGDTSIVTFKGHRVQKSLIRAKFSPAASTGQRYIYTGCSTGRLIIYDILTGKMVNGGLEGHKDIVRDVSWHPRRNEILTSSWDYTVNINTFQDKSTEKKRSRSQFMPSDFDSDLMDVAPPLRRSRRIAQRLAGASTSRRKMTSTAFEQVVLSEKKRTSSPICESCGKEFSNVHTLNCHRKQVHEGIKNFQCSICSAKFTTRYKTMRHFQAVHSELRNYTCDYEQCGSTFKTSDMLSKHQRIHFPGPYKCDACLEVFKYKSGWDYHVQKKHRDSGLKTVTIYKCSECPREFKTSAAYENHKKLQHPVPSQPFQPKELNPKSRRQQVKVVKSSEAEFECHYCHKRYKSKANFIVHLASHENEEEMQDYDFIIKEPETQVELDETEQHLEEEEEEVHESLDEFAGDNLLKGVDEDLVTIFKFETERFVDGPESFSNTELDNELIAKETTGEIEGEMYLYDDGADYMDDEEQLEETVEVEHEYIEYLTTDDIDQTTILNETRNMKPRKSTPNANNTGICDECGKYFKHSHHLKRHIMRKHQTDSKKLECDFCGAKFLLSYDLKRHMIKHSTKRAFKCNLCENAFKTASYLKNHVEAVHTEKTEKKFQCKMCERSYVHERHLVYHMRKHTNDLRFSCDLCDPPQLFHYSDAVKWHKVRHHGQPAPFSCTICTKRFIHEKSLTTHMKAHQENGTLAVNCPICGKSISEKRHLKRHIRTHDNHKFHCPCGFSFKERHQLTKHAKTCQFEWEGDIEEFVYEAVDAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-