Basic Information

Gene Symbol
ZIPIC
Assembly
GCA_028537555.1
Location
JAQMYT010000011.1:15336979-15338406[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0002 0.019 16.0 0.0 2 23 147 168 146 168 0.97
2 11 1.6e-05 0.0015 19.4 0.6 1 23 174 197 174 197 0.94
3 11 9.3e-05 0.0089 17.0 2.8 1 23 204 226 204 226 0.98
4 11 2.4e-07 2.3e-05 25.2 1.1 1 23 232 254 232 254 0.99
5 11 4.3e-06 0.00041 21.2 0.4 1 23 260 282 260 282 0.98
6 11 0.00053 0.051 14.6 2.1 1 23 288 310 288 310 0.97
7 11 2.2e-06 0.00021 22.1 0.6 3 23 318 339 317 339 0.97
8 11 0.0032 0.3 12.2 0.7 2 23 345 363 344 363 0.85
9 11 0.039 3.7 8.8 0.4 1 23 369 392 369 392 0.90
10 11 0.026 2.5 9.3 0.4 1 23 398 423 398 423 0.94
11 11 8e-06 0.00077 20.3 1.1 1 23 429 452 429 452 0.97

Sequence Information

Coding Sequence
ATGGATTCGAATGTGTGTAGAATATGTTTGGATAAAACCGCAACAGTCTCTCTTTTCGACAAAGAAGATGATATTCAACATAGTGTTAAAATAATGCAGTGCGTGAACATAAATGTAACGCAAGATGACGGACTGCCTGGCATGATGTGTGCCAGCTGCGCGAACGAGCTTGCCATAACGTACGCATTTATACAAAAATGCGAAGCTTCAGATAAAACGTTGCGGTCCTTATCCGCCGATTTCTTAGAACTTCAACAAAATATTGAAATAGACATTAATCTTGAAGACATTAAACACGAGCTCGATCAAGACAACTATGATTTTTTATCTGATTCAGTTTCGGAACAAGTTCAGAGTACGGCCAAGAAGAAAAGCAAATGTAATGAAAGAAGAAAAATTGAAAGACGAAAATTTAAAAGAGGCAAAATGGGGCCAATACAGTGTGTCATTTGTGGCCTGCTGGTGACCAGCCCGTCggcgatgcagagccacatgcgcacacatacgggcgagaagccgttcgcctgccccttgtgcgatgcaaagttttccaccaaaggttccctgaagcgacacaatgacacttatcatcgtgagcgcgaaaggaaattcacgtgcgagacttgcggcaattgttttttcaggaaaaacgacatcataacccacatgagagttcactctggtgagcggccttatgtctgtcccttttgctccaaacgcttccggcaagctgcatccctgataaggcacaagagaacacatacgggtgagaaaccatactcctgtccaatatgtgacaagaaatttggtgacaaAAACCTTGTTCAAAAGCATCAAAGCGTGCACAGCGATGAGCGGCGCTTCAGTTGTCACCTGTGTAACAAGTCCATGAAGTCCAAAACTGCACTAAATGCTCACTTAAGCCTGCATACTAATGAGAAGCAAAACATTTGCACTTTTTGTGGAATGGCTTTCTCAATGAAAGGTAATCTACGTACACACATGAGGCGGGTACATTCTGAGAGATCTGGACAGTGTACAGTTTGTTTGAAAACATTTTCTGATTTAGAAGTTCACATGCGAAAGCACACAGGGGAAAAACCCTTTATCTGTGGTTTGTGCAGCGCAGCATTTGGAGTTAAGCGCAGTCTAGCCCACCATATGGTGTTTAAACATGAAAATGCAAAAAAGTTCAAATGCTCAATAGGAGAGTGCACTCAAACATTCCCCACTGCTACAATGCTAGAGTTCCATTTGTTAAAGCAACACACAAACCACACACCATACATCTGCCAGTACTGTTCAAGAGGTTTCTTTCGCACCAGCGACCTCTCCCGGCACATTCGAGTCAGTCATTTGGATGCTCAAATGAAGTCCACCACATTGAAGCCTATAATAGTTAAGCCTTACACCTTGCAATACTCTTAA
Protein Sequence
MDSNVCRICLDKTATVSLFDKEDDIQHSVKIMQCVNINVTQDDGLPGMMCASCANELAITYAFIQKCEASDKTLRSLSADFLELQQNIEIDINLEDIKHELDQDNYDFLSDSVSEQVQSTAKKKSKCNERRKIERRKFKRGKMGPIQCVICGLLVTSPSAMQSHMRTHTGEKPFACPLCDAKFSTKGSLKRHNDTYHRERERKFTCETCGNCFFRKNDIITHMRVHSGERPYVCPFCSKRFRQAASLIRHKRTHTGEKPYSCPICDKKFGDKNLVQKHQSVHSDERRFSCHLCNKSMKSKTALNAHLSLHTNEKQNICTFCGMAFSMKGNLRTHMRRVHSERSGQCTVCLKTFSDLEVHMRKHTGEKPFICGLCSAAFGVKRSLAHHMVFKHENAKKFKCSIGECTQTFPTATMLEFHLLKQHTNHTPYICQYCSRGFFRTSDLSRHIRVSHLDAQMKSTTLKPIIVKPYTLQYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01143281;
90% Identity
-
80% Identity
-