Basic Information

Gene Symbol
-
Assembly
GCA_963991005.1
Location
OZ022562.1:12112323-12117069[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 2.3e-05 0.002 19.8 0.0 3 23 44 65 42 65 0.96
2 24 1.1e-05 0.001 20.7 1.7 1 23 71 94 71 94 0.98
3 24 4.3e-05 0.0038 18.9 2.7 2 23 136 157 135 157 0.98
4 24 0.017 1.6 10.7 0.0 1 23 164 187 164 187 0.94
5 24 0.37 33 6.5 4.3 1 23 193 216 193 216 0.96
6 24 2.8e-05 0.0025 19.5 3.7 1 23 221 243 221 243 0.98
7 24 0.014 1.3 11.0 3.1 3 23 249 270 249 270 0.98
8 24 0.027 2.4 10.1 1.3 2 21 276 295 275 297 0.93
9 24 0.57 51 5.9 0.3 5 23 309 328 308 328 0.71
10 24 1.9e-06 0.00017 23.2 3.3 1 23 335 357 335 357 0.98
11 24 0.00012 0.011 17.5 7.3 1 23 363 385 363 385 0.97
12 24 0.00042 0.037 15.8 0.3 3 21 393 411 391 412 0.95
13 24 0.00077 0.069 15.0 0.8 1 23 438 461 438 461 0.93
14 24 0.15 13 7.7 0.3 1 23 467 490 467 490 0.97
15 24 5.7e-06 0.00051 21.7 0.5 2 23 496 517 495 517 0.97
16 24 0.1 9.1 8.3 0.0 1 23 524 547 524 547 0.94
17 24 1.4 1.3e+02 4.7 3.2 1 23 553 576 553 577 0.93
18 24 4.2e-05 0.0037 18.9 4.3 1 23 582 604 582 604 0.95
19 24 0.00025 0.022 16.5 5.8 3 23 612 633 611 633 0.97
20 24 0.013 1.2 11.1 0.1 2 20 639 657 638 658 0.94
21 24 0.91 82 5.3 0.6 2 23 672 691 672 691 0.84
22 24 4.8e-05 0.0043 18.7 2.3 1 23 698 720 698 720 0.98
23 24 6.2e-07 5.5e-05 24.7 4.7 1 23 726 748 726 748 0.98
24 24 6.9e-05 0.0062 18.2 3.0 3 21 756 774 754 775 0.96

Sequence Information

Coding Sequence
ATGAAAACTGAATTCGATTATCACGATTCAAATCAATTTGTTACCCAAAAAGTGAAAATTGAATTCGAGTATAACAATTCCAATCAGCTTGTTAATCAAGAACAATTACTCGTGTGCAAGATTCTTTTGTGTCCTGTGTGTGGAAAAGGTTTTAAGGGTCAGGATGGATTGAAAAAACACATCGCGTCGATACATTCAGATGAGCGACCATATCAGTGTCAATTATGTGAGAAAGCTTTTAAATTCAACTTCCACCTTGCTGCGCACATAAAAACCGTTCATTCCTCCTTGGAACTTAAggAGAGTATCGAGACGGAATTCATAGGCGACGATTCCACTCAGCTGGAATCGATTCCAAACAGCCTCAACAAACATATTGAGACCGTACATTATCCATCTGaagtaaaatgtaaaatttgtaaacgAACATATAAGAATAAAACGTCGTTAAGTTTGCATTTAAGATCTCACGATCCAAATAAAACAACTTATCCATGTTTAGTTTGTGATCGTAAATTTGGCACAAGGAACGCTGTAAATATACACGTTGCGTCCGTCCATCTCGACGAACGGCCGTTTCACTGTGTAATTTGTGATAAGTGGTTCAAGGCAAGTAAAATGCTTAATCACCATAAGCAAAGTCAACACGGAACAATACTGTTTAAATGTACAACTTGTGAAAAAACCTTTAAAAGTAAGACAACGCTAAGAGTGCACGAGCAACGACACCAGAACCTCAAGGGTTGTCAAATGTGCGATCAACTATTTCATTCAAATTCCCTGTTGCAATTACATATGCAAAAAAAGCATGCACCTCGTACCGTTCCTTGTACCATTTGTAAGAAAATGTTTCCAACCGTAAAATTGATGATGGAACACCAAAGATGTCACACGGATAAGAGTAGGAAAGGCACCGTTTTAGAGGAATGTCCTTATTGCAGTAAGAAATACCTGCAATTAAAAGAACATATTAGGGATATTCATAAAAGGGATGAGAAAAACTTTGTGTGCGATCACTGTGGTAAATATTTTAGAAGGAATAGAGAACTTAAGCAACATCTTATGATGCACCAAGGAATAAGACCACATCATTGTAAAGAATGTGGCAAGAATTTCATTCAATATCATGACTTAAAAGTGCACACCCGTACACATACGGGGGAAAAGCCGTATGGATGTGAAATTTGCGGTAAAAGATTTATTTACATACAACAATTCACTAGGCATATGAAGCAggaaattatcgaaatacaaTTTGATGACTTCGATTCCATTCCAACTGACAGCGAACAAGAACCTGTGGGCAAGATTTTTTTATGTCCCTATTGTAGAAGAGCATTTGATGAAAACCACCAGTTGACTAGTCATTTAGCATCAATACATTCTGAAGAACGACTATATCCGTGTCAGTTTTGTCTAGACACTTTTAAGTCACAAGAGATCCTCAATAAACACATTGAAACTGTGCATTATCCTTCCAAacttaaatgtaaaatttgtgaACGAACATATAAGAATGCGGCGGCGTTGAAGCTGCATTTAAGAACGCACAATCCAAATAAAaaatcttatccgtgtttaaTTTGTAATCGTGAATATGGTACAAGAAATGCTGTTAACGTTCACGTTGCCTCTGTTCATCTTAACGAACGGCCGTATCACTGTGAAATTTGTGACAAGTGGTTCAAGGCAAGTAGTATTCTTAATCAGCATAAACAGAATCAACATCATCTGGAAATTCTGTTTAAATGCAAAAGTTGTGAAAAAACATTTAAACATAAGTCGAATTTAGAAACGCATGAGGCACAACATCTTAAACAGTCCGCGAGATGCTGTGAAATTTGCAACCAAGTATTTTATTCACACTCTCAATTCAACAGACATATGCAGACAAAGCATGCGCCTCGTACAGTTCCCTGTACCGTTTGTGACAAAATGTTTCCTACTTTAAACCGTATGCAGAAACATCAAGTATGTCACACGGATAAGAGTAGTAAGGTTACTATTTCTGAAGAATGTCCTTTTTGCGGCAAGAAATATCTGCAATTAAAAGAACACATCAGAGATATGCATAAAAGAGGCGAGAAAAACTTTGTATGCGATCACTGTGGTAAatattttagaagaaaaaatgaGCTGAAACCACATCTGATGATGCACCAAGAAATAAGGCCACATCAGTGCAAAGAATGTGGCAAAAAGTTTCGCACTAGCCAGAATTTAAAGGTGCATACTCGTTCTCATACTGGGGAAAAGCCTTTTGGGTGTGAACATTGCGGCAAGAGATTTGCTCATAAGCAACAATTTAATAAGCATATGAAACTGATGCAGTGTCTCTCATAA
Protein Sequence
MKTEFDYHDSNQFVTQKVKIEFEYNNSNQLVNQEQLLVCKILLCPVCGKGFKGQDGLKKHIASIHSDERPYQCQLCEKAFKFNFHLAAHIKTVHSSLELKESIETEFIGDDSTQLESIPNSLNKHIETVHYPSEVKCKICKRTYKNKTSLSLHLRSHDPNKTTYPCLVCDRKFGTRNAVNIHVASVHLDERPFHCVICDKWFKASKMLNHHKQSQHGTILFKCTTCEKTFKSKTTLRVHEQRHQNLKGCQMCDQLFHSNSLLQLHMQKKHAPRTVPCTICKKMFPTVKLMMEHQRCHTDKSRKGTVLEECPYCSKKYLQLKEHIRDIHKRDEKNFVCDHCGKYFRRNRELKQHLMMHQGIRPHHCKECGKNFIQYHDLKVHTRTHTGEKPYGCEICGKRFIYIQQFTRHMKQEIIEIQFDDFDSIPTDSEQEPVGKIFLCPYCRRAFDENHQLTSHLASIHSEERLYPCQFCLDTFKSQEILNKHIETVHYPSKLKCKICERTYKNAAALKLHLRTHNPNKKSYPCLICNREYGTRNAVNVHVASVHLNERPYHCEICDKWFKASSILNQHKQNQHHLEILFKCKSCEKTFKHKSNLETHEAQHLKQSARCCEICNQVFYSHSQFNRHMQTKHAPRTVPCTVCDKMFPTLNRMQKHQVCHTDKSSKVTISEECPFCGKKYLQLKEHIRDMHKRGEKNFVCDHCGKYFRRKNELKPHLMMHQEIRPHQCKECGKKFRTSQNLKVHTRSHTGEKPFGCEHCGKRFAHKQQFNKHMKLMQCLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-