Basic Information

Gene Symbol
rst2
Assembly
GCA_031353405.1
Location
JASFAT010000095.1:233522-243711[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.0089 0.57 10.9 0.0 3 23 139 159 137 159 0.97
2 15 0.0025 0.16 12.7 2.9 1 23 288 310 288 310 0.98
3 15 8.7e-05 0.0055 17.2 1.2 1 23 316 339 316 339 0.96
4 15 0.023 1.5 9.6 6.1 1 23 344 367 344 367 0.93
5 15 2.6e-06 0.00016 22.1 0.5 2 23 518 539 517 539 0.98
6 15 7.2e-05 0.0046 17.5 2.4 1 23 545 567 545 567 0.98
7 15 0.061 3.9 8.3 4.2 1 23 630 652 630 652 0.96
8 15 0.32 20 6.0 0.3 2 23 660 681 659 681 0.96
9 15 0.0041 0.26 12.0 2.9 1 23 687 709 687 709 0.95
10 15 6.8e-05 0.0043 17.6 3.2 1 23 715 737 715 737 0.96
11 15 0.0018 0.11 13.1 2.3 1 23 746 768 746 768 0.98
12 15 0.00015 0.0093 16.5 0.9 2 23 815 836 815 836 0.97
13 15 0.034 2.1 9.1 5.9 1 23 853 875 853 875 0.96
14 15 1.8e-06 0.00011 22.6 0.6 1 23 881 903 881 903 0.98
15 15 5.1e-07 3.3e-05 24.3 3.1 1 23 909 932 909 932 0.98

Sequence Information

Coding Sequence
atgaatttaaatgtgACTATGGAAGTAGATCCATTATCAACATATGATTATCAATCCTATGATGGTTTCAGTTCATTTCCAATTACCACAAATTGCGCTCCATATCCAAGCACCGAACCTGTATACCACAACTTTAATGGTAAAAATGAAGCATATCAAAAACCAAAGTGTGGTGGTGAATTAGAGCAAAGTGCAAATTCTCATTTAGATAATAGAACGAAAACTTTAGATAACGCAATAAACTCCTTAAATAGCTcagataaaaattcaaataaagatGAAGTGAACCCTATGAGAGATAAAGATGACGATACACAAAATGTATTGAGGAAAATTAAAACGGAGGGAAAAAATGGTAAGAGAAGTAACCACCCGTCAAAGAAAATAGCCGATCGCAATTATCCATTCTACGGCTGTGCCGtatgtaatataagttatacattgTTAAGTGAATTAGACAAACACATAGCCACTCACAAAGACAGATTAACAAGCTATGGTTTAAGGATAAAGAATCAGATTAAGAGGAAAAAGTTGAGGAAAGAACAAAAGAAATTGAAGAAATTAGGCAAAGCgattaaaaaagagaaattgGACATTGAGATAGAAATCAAACCTGAAGACGGGTACATAGGTGAAACAAAAGCTGAGGATTATGTTTCGGATAATAAAGACGGCGTTTTTGATTCTGTAAATCCAGACAGCgctatattgaataaaaatataaataataatgataagaaCAATACGGTACCACAAGAATCTAAAGAAAACACTTCAAATAGTAATGATAAGAAGAAACACAGTAAGAATAAAATTGAGAAGCAGAATGCAGAGGAGATGAATAATATGGATAAGATCTTTAAATGCTTTGCCTGTCAAAAGCAATTCACGTTAAGTTATTACCTGAAACTACATGTCAGGTCTCATACAGATGAGAAGCCGTACACTTGTGCGGAGTGTGGACAGTGTTTCATAACTGCCAGTAAACTGGGTAGACACAATAAAAGAATACACTTGGCCATCAGGCACCAGTGTAggatatgttacaaatatttttccagATTCGAGTACTTAACACGGCACTTTGACAAAAAGCATCCCGAGGATAAATTGGAGGGAGAACCATATGACTACAATGCAATATTACCATATTTAAAAGAATTGGAAGCTCAACTTCAATCAAAGCCCGAGGAGAAGTCGACCGAGGGAGACACCAAGCCGAATAGTGGAGAACCTGATGAGAGTATAGATAAAAGAGATAATGCTGTGAATCTACCAGTTAAGGTAGTCCTAGAAGCACCAACGCTAGAAGTTACTTTTGAGGTGCCTATAAAGGAGGAAACAGAAGATTTTGATGGTGTGGACAATGCATATGATGAGATAGACAATATAGCAAATGATGATGTTAAGGATGACAGTATGAAAGAGGAgagCCCCTCTGATGATGAATATTTTCCTTCCAACACCTGGGTAACGTCACCCAAAGAGTACAGAGCAGCCAGTCCAAACCCAACTAGAGGTAAACGACAAAAGTCCGAGGGACCCATCCAGTGCAATGTTTGCGAGAAGACAATCAGTTCCTCGTCTTACCTGAGGATACACATGAGAACCCACACCGGGGAGAAGCCGTTCAAATGTTACGTGTGCGGTCGGGGATTCATCACGTCCAGCAAGATGCATCGACACGTTTTGACCCACTCGGAGTCATGGAACGAATCCGCCGACGTGAAGTTGGAAGTGAAAACTGAAGAAGATGATGCGGGTGGTACggtgaagaaaaagaagaaacgcAGCAAAGACGCATCGAAGAAAGGGAAACCGAAATTCTTGAAGAAATCTAGAAAGACGGTGGAGAAACAGAAGAAACTCCATCAGAAACGGCCGCACGCTTGCGAATATTGCAATAAGAGGTTCCTTCACATCGAAACACTTCAAGTCCACAAGAAGTCTCACGATGGCGAAGAGTTGGTGCTGAAGTGTAACTTCTGTTTGATGAAAGTGGACGACGAGGAGAGTCTGAAAACCCATGAGGCCACGCATGAGGGACCAAAACCATTTTTGTGTACTCTATGCGGGAAGACGTACAAGAAGAGGGAGACCATGATGTACCACAGGAAGAACCACATACCAGAGAAGGAGCACGTCTGCGAGATATGCTCGAAGAGCTTCAACTCGCCGTGTAAGCTGCAGAAGCACATCGTCAGCCACCGGGTGGACAAGTTCGTACTCCGGTACGAGTGTCCCGTGTGCGCCCACATGTTCAACACCAAATACCACATCCAGATGCATCTGGTGACCCATCAGAAGGAGGGGCTGATAGTGGAAGAGAACCGCAGTGAGATCCTCGCAATGGTCTTGCAGAACGCGAGAAAAATACCCAAACACCCCGACGCCCCCAACAACCTCACCGACGTGGTGCCGCCGGACGAGAGGAGCCGCGTGTGCAACATATGCGGCCAGGTGTTCCAGCACTTCTACTATCTAGAGGAGCACCTCAAGAGCCACGGCTCCAAGATAGCTCTAGAGGACGAGCAGGTGAAAGAGGAGAAGAAGCACGTGTGCAAGGTATGCAACAAGGGCTTCAAGCTGCACTACTATTTGAAACTGCACAGCTTCACCCACACCAAGGAGAAGCCGTACATCTGCCAGCAGTGCGGCAAGGGCTTCATAACCCGCGGCAAACTCAAACGGCACCTGGAGACCCACACCGGCTTGAAGAAGTACCAATGCCATATATGCTACAAGTTCTTCACCCGGCCCAGCTATCTGAGGATCCACGTGAGGACCATCCACGGAACCCAGGATTACAACTTCAGGTTGGACAAGCAATACTTGGGTCATGCCGTGCCCAGTTTGGagtag
Protein Sequence
MNLNVTMEVDPLSTYDYQSYDGFSSFPITTNCAPYPSTEPVYHNFNGKNEAYQKPKCGGELEQSANSHLDNRTKTLDNAINSLNSSDKNSNKDEVNPMRDKDDDTQNVLRKIKTEGKNGKRSNHPSKKIADRNYPFYGCAVCNISYTLLSELDKHIATHKDRLTSYGLRIKNQIKRKKLRKEQKKLKKLGKAIKKEKLDIEIEIKPEDGYIGETKAEDYVSDNKDGVFDSVNPDSAILNKNINNNDKNNTVPQESKENTSNSNDKKKHSKNKIEKQNAEEMNNMDKIFKCFACQKQFTLSYYLKLHVRSHTDEKPYTCAECGQCFITASKLGRHNKRIHLAIRHQCRICYKYFSRFEYLTRHFDKKHPEDKLEGEPYDYNAILPYLKELEAQLQSKPEEKSTEGDTKPNSGEPDESIDKRDNAVNLPVKVVLEAPTLEVTFEVPIKEETEDFDGVDNAYDEIDNIANDDVKDDSMKEESPSDDEYFPSNTWVTSPKEYRAASPNPTRGKRQKSEGPIQCNVCEKTISSSSYLRIHMRTHTGEKPFKCYVCGRGFITSSKMHRHVLTHSESWNESADVKLEVKTEEDDAGGTVKKKKKRSKDASKKGKPKFLKKSRKTVEKQKKLHQKRPHACEYCNKRFLHIETLQVHKKSHDGEELVLKCNFCLMKVDDEESLKTHEATHEGPKPFLCTLCGKTYKKRETMMYHRKNHIPEKEHVCEICSKSFNSPCKLQKHIVSHRVDKFVLRYECPVCAHMFNTKYHIQMHLVTHQKEGLIVEENRSEILAMVLQNARKIPKHPDAPNNLTDVVPPDERSRVCNICGQVFQHFYYLEEHLKSHGSKIALEDEQVKEEKKHVCKVCNKGFKLHYYLKLHSFTHTKEKPYICQQCGKGFITRGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRLDKQYLGHAVPSLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-