Basic Information

Insect: Balanococcus diminutus
Gene Symbol: TARDBP
Assembly: GCA_959613365.1
Location: OY390717.1:8545251-8560592[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 4.7e-05 0.0037 17.8 7.3 1 23 463 485 463 485 0.98

2 7 0.00015 0.012 16.2 4.3 1 23 491 514 491 514 0.93

3 7 1.9e-08 1.5e-06 28.5 0.9 1 23 655 677 655 677 0.99

4 7 0.00027 0.021 15.5 0.4 1 22 683 704 683 707 0.90

5 7 0.014 1.1 10.1 6.0 2 23 810 831 810 831 0.97

6 7 1e-07 8.1e-06 26.2 2.4 1 23 838 860 838 860 0.98

7 7 1.3e-05 0.00098 19.6 1.7 1 23 866 889 866 889 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	4.7e-05	0.0037	17.8	7.3	1	23	463	485	463	485	0.98
2	7	0.00015	0.012	16.2	4.3	1	23	491	514	491	514	0.93
3	7	1.9e-08	1.5e-06	28.5	0.9	1	23	655	677	655	677	0.99
4	7	0.00027	0.021	15.5	0.4	1	22	683	704	683	707	0.90
5	7	0.014	1.1	10.1	6.0	2	23	810	831	810	831	0.97
6	7	1e-07	8.1e-06	26.2	2.4	1	23	838	860	838	860	0.98
7	7	1.3e-05	0.00098	19.6	1.7	1	23	866	889	866	889	0.96

Sequence Information

Coding Sequence: ATGAGTTCGAATTACGTTCGTGTCAGCGACGAAGTCGGCGAAGAGCCGATCGAGTTACCCATCGAAGAAGATAATACACTGTTGTTGTCCACAGTATCTGCTCAATTTCCTTGCGTTTCTGGGTTAAAATACGCCGTCGAGAGTTACTACAGAGGAGTGAAGCTTTGCGAAGGACGTCTCTATCCACCGGATGGATACTGGGGTAAAACCGTGTACTATTGCGTGTTCCCCAAAGAGAATAAGAGGAAGTGCAACGATAGCCCTTCGAATTTCCAAATCAAAACGAAACGATTCGAAGCGAATTCGTCGATTGATCTGATAGTCTTAGGATTACCTTGGCAGTTGAGCGAAGCACAATTGAGAGAATACTTCCAAACGTATGGTAGCGTTAAGATGGCTATGATTAAACGCGATCTAATTACCGGAAGGTCGAAAGGATTTGGATTTATTAGATTCGATAATTACGACAGTCAAGTcaaagttttatcaaaaaggCACTTCATTTCTGGACGTTGGTGTGACGTTAAAATACCAGATTCAAAAgaggGATCAGACGTACACATCCCTTGTAAAATCTTCGTCGGTCGTGTCAGCGAAAATATAACCGTAGACGATCTACGCGGCTACTTTAGTCAATTCGGTGAAGTAACAGATGTCTATATACCAAAGCCATTCAGATCTTTCGCCTTCGTCACTTTCGACAGTCCGGAAGTGGCTCAAAGTCTAATAGGCGAAGATCACGTCATCAAAGGTGTATCTGTCCATGTCTCCGAGGCATCTCCCAGGTATTCCAACTCGAGAACGTCTCGTCAACGTAATCCCTTCTGGCAGCCTTCCAATTCACCCAACAAGCATCAACCTGCCGTCGACTCGAACACCGTAGCTTTACTGTCCGCCATAGCTGGTAATCCTTCGGTTCTCGCAGCTGTTAACCAAATAGGACTTAATTTTATCATGGCGATGCAAAAATCTGTAAGAATCTGCGAAGAAGAAGGCTGCGACCCCACACAATTACCTCTGAACGGATTAGATGGTTCCTTGTCGCTCTcggatttgaagaaattcttccCAAAGGCCATAGGCTTAAGATACTACACTGAGAACGATACTATACGCGGTGTGAAGCTCACCAATGGTAAATTTTACCCGCCAATCAACGGATGGGGAAACGCTGTGTATTATTGTACAACTCTAACAGAATCCGACCCTGCTGAGAGTGACGTAAAATCGGAAATGTACGGTAGTATCGAGAACGTCACGATTCTCGAAAATAACGATACTCAGTCAATCGAACAAAACAGCCTGGAAAGTAACGAAAGCTCGGATAGTTTTTCAGTGCATCGATATCATCACGATGATAAAAAAATACCCACCGCTAGACGACCTCATCGATGCGATATATGTGGTAATTGTTTTACGCAACAGTCTCATATGCTGCGTCATCGACGTATTCACACCGGAGAGAAGCCATTCGCTTGTGAACATTGTGGCGAACGATTTTCAAGATCTGATAAACTGAAATTACATTATGTTCGATGTCATGTGAGTTCTGTATCGCTGGTCGAGATAATTCGTAAAGAAACAACTCCTACGAAAGAAAGACGAGAAACAAAATCCAAGGTCATAAACGATGCCATCGACTGGAGCGCCAAAGCACCCTCATCTAGCTCCACCAACGACTCTCCTACTAAAACAAAACACCTAACAGTACGTTTCAAGAAAACATCAAACATAGATCTTGATAATGGGCAAGATGGGTACTACAGCGTCGTAAACATGGCAGAGGTAGAGATGGAAGACGACGAGCCCGTCACTATTACCCCAATTAACGTACCGAAACTTGTAAAAGAAGAACCTATCGTCAAAGAAGAACATTTTGTTAAAGAAGAACCTGCTTCGCCTTCGCCTCCTCTGCAGGAATCGCTCTTCATCGATCCATCTAACATGGCTCTCGATCGTAAGTACAAATGTGACGAGTGTGATAAACCATTCgcgaagaaaaatcaattacaaAGACACATGCGAATTCACACCGGAGAGCGACCGTTCCGATGTCAAATATGTATGAAATCGTTCACTCGTATCGATGCTCTGAAACGACACACCGCCTCAATGGGTCACCAAAAGCAGAAGttgGAATTGAACGATGCGGATAATGTCGAATCGGTTACCGAAATTTTGATCGACACGTATCCCGATATATTGGCCGATGATATGGAAGTGGATCCGTTAAACGATGAAAATTCCAGTAACCGAGACGACGCCGAAGACGACAATGATATTGAAACACATTGCGACGTCGCCAGCTTCGCTCAAGTCACCTATGCTAATTTGGAGCCTGTAAATAATGTGAAAGAGGAACCTCTGCCGGAACCCGAAGAGAAGCCCAAGACTACTACGAGAAGAGGCAGGCAAGGCAAAGAGAACTATTGCCATCAATGTAATCATCTGTTTACGAATAAgtttaattacaatttacaCATGGAGTCGCACAGAAAACCAGAGAGATCGTACAAATGCACTTATTGCGATTACGTATTTGGAAGACAGTCGCATTTAACCAGACATATTCTCATTCACACTGGAGAAAAACCTTTCCAGTGTAAACAATGCGACGAACGATTCTCGCGTTCTGATAAGCTCAAGTTGCACGTCGAAAGGACCCATACTTACGGATACAAAAATGGCAAACAGTCAATTCGAATTGATGCTGTGTACGTGATCGAAGAAATGGAATTCGACATGAAGCAGTCAAATTGGAACGAATAA
Protein Sequence: MSSNYVRVSDEVGEEPIELPIEEDNTLLLSTVSAQFPCVSGLKYAVESYYRGVKLCEGRLYPPDGYWGKTVYYCVFPKENKRKCNDSPSNFQIKTKRFEANSSIDLIVLGLPWQLSEAQLREYFQTYGSVKMAMIKRDLITGRSKGFGFIRFDNYDSQVKVLSKRHFISGRWCDVKIPDSKEGSDVHIPCKIFVGRVSENITVDDLRGYFSQFGEVTDVYIPKPFRSFAFVTFDSPEVAQSLIGEDHVIKGVSVHVSEASPRYSNSRTSRQRNPFWQPSNSPNKHQPAVDSNTVALLSAIAGNPSVLAAVNQIGLNFIMAMQKSVRICEEEGCDPTQLPLNGLDGSLSLSDLKKFFPKAIGLRYYTENDTIRGVKLTNGKFYPPINGWGNAVYYCTTLTESDPAESDVKSEMYGSIENVTILENNDTQSIEQNSLESNESSDSFSVHRYHHDDKKIPTARRPHRCDICGNCFTQQSHMLRHRRIHTGEKPFACEHCGERFSRSDKLKLHYVRCHVSSVSLVEIIRKETTPTKERRETKSKVINDAIDWSAKAPSSSSTNDSPTKTKHLTVRFKKTSNIDLDNGQDGYYSVVNMAEVEMEDDEPVTITPINVPKLVKEEPIVKEEHFVKEEPASPSPPLQESLFIDPSNMALDRKYKCDECDKPFAKKNQLQRHMRIHTGERPFRCQICMKSFTRIDALKRHTASMGHQKQKLELNDADNVESVTEILIDTYPDILADDMEVDPLNDENSSNRDDAEDDNDIETHCDVASFAQVTYANLEPVNNVKEEPLPEPEEKPKTTTRRGRQGKENYCHQCNHLFTNKFNYNLHMESHRKPERSYKCTYCDYVFGRQSHLTRHILIHTGEKPFQCKQCDERFSRSDKLKLHVERTHTYGYKNGKQSIRIDAVYVIEEMEFDMKQSNWNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -