Basic Information

Insect: Bactrocera latifrons
Gene Symbol: topi
Assembly: GCA_001853355.1
Location: NW:42404-45680[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.9e-05 0.0016 18.3 2.6 1 23 168 190 168 190 0.97

2 10 0.007 0.39 10.8 1.1 2 23 225 246 224 246 0.97

3 10 0.032 1.8 8.7 0.1 2 19 308 325 307 327 0.94

4 10 0.028 1.5 8.9 1.6 1 22 376 397 376 400 0.90

5 10 1.1 59 3.9 0.3 2 20 415 433 414 437 0.76

6 10 9.3e-07 5.2e-05 23.0 2.3 1 23 457 479 457 479 0.95

7 10 0.0022 0.12 12.4 1.1 1 23 485 510 485 510 0.95

8 10 0.32 18 5.6 1.7 1 23 516 538 516 538 0.88

9 10 2.7e-08 1.5e-06 27.8 0.4 1 23 544 566 544 566 0.99

10 10 0.031 1.7 8.7 1.4 3 23 574 595 572 595 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.9e-05	0.0016	18.3	2.6	1	23	168	190	168	190	0.97
2	10	0.007	0.39	10.8	1.1	2	23	225	246	224	246	0.97
3	10	0.032	1.8	8.7	0.1	2	19	308	325	307	327	0.94
4	10	0.028	1.5	8.9	1.6	1	22	376	397	376	400	0.90
5	10	1.1	59	3.9	0.3	2	20	415	433	414	437	0.76
6	10	9.3e-07	5.2e-05	23.0	2.3	1	23	457	479	457	479	0.95
7	10	0.0022	0.12	12.4	1.1	1	23	485	510	485	510	0.95
8	10	0.32	18	5.6	1.7	1	23	516	538	516	538	0.88
9	10	2.7e-08	1.5e-06	27.8	0.4	1	23	544	566	544	566	0.99
10	10	0.031	1.7	8.7	1.4	3	23	574	595	572	595	0.95

Sequence Information

Coding Sequence: ATGGTTAATGAAACAGTGAAACAAACAACGGGGTCATTCGATGCAACAGAAGAAGAATTGAAACTTTTGCAATTCCTGGAGACGCAACCCCAAAGTAGTCCGCTTGATACTAAATTATATATTCCGCCCGATGTTCCACCATCAGCTTATCGAATTGTGAAGTGTTCCAATTGCAACTGCCTCTTTGATATCATATCTTTTCAATCTCACATATGTGATTACGATGAACACCATAATCTAATCATCCCCCCAGCTGCATCTACACCTATTAATAAGCCCATCAAGGAAGAACCACTATTGCCACCGGAACCGGCATGCATTCGATTATTGCGCGAAAATCAGATACGCATTCGGCGTTTCTTAAAAGATGAACTTAAATATGATGTTAATGCgtcaataaataacaatttaaacaattcgAGTAGTACTTTAGGTAATACATCAAATACATCGACAGGCTCGACATCATCGAATACTGCTAGCAAAAAGCAAGATGGTCCTCATGAGTGTACACTATGCGAGCGTAAATTCGTGCATGCATCAGGCCTGTTGCGGCATATGGAGAAACATGCAATGGATCTTATACCAACCCCAGGCGCTTCGTCAGGTGGTAAAACGACTTCATCACAATGTAGCTCCTTACAGAGTGTTAATGGACTGCGTGTTGTCATTAAGTGTACTCTTTGTGGAAGAGTATTCTTTGAGCCATTTGCTGCTTTCAAACATTTATGTTCCCACTTTCCCGGAAGTATGCAGGAAGAAAAAGAATTCGATAATTGTGCTGAAATTCCGTACGAATCCTATGTAGACGATGCtatgaattttttgaagatggagatCAATAATTGTGCGGGGCCGCTAACAGTTCACGGAGATAAATCACCTGTTTACCTCAAAATGGTTATTTTAAGTTGTATTTTGCAGTGtgaattttgtgattttgttttcTCGGAAGTATCCTATTTATTTGTACATTCCGCTTGCCATTTGCCTGAACGACGTTTTGAATGCTTTTCATGCGATATTCATATGCGCACGTCTAAAGAAATATGTGCGCATTGGCAAGCTGAGTGTGTATTTATGCGAGAAAATCTTAAGGTGCATCAAGCTTCTACACAGCGTTACTTTGTTTGTAATGTTTGCGAGAATAAGTTTCAATCCCTTGATCAGTTGCATGAGCATAgatATACAGCTTATCATTTTTTTCCACGTTTGAACAAATGCCTTGGTGTACTGCAACTACCTTGTGAGTACTGCGATGTTGTATTTGAGTTTGCGCAAGAATGTGTTGCCCATTATGAAGAAAAGCACTATAAGAAGTATAAACGCGATAAAGATGGAACTGGTTCTTCCAGTAAAACCCGCCAATACTTATGTGATATGTGCGGAAAATCATATACCCAATCCAGCCACTTATGGCAGCATTTGCGTTTTCATCAAGGCGTAAAACCCTTTGCTTGCAAGGAACCTGGTTGTACACGTAAATTTACCATTCGTCCTGACTTGAATGATCACATTCGCAAGTGTCATACTGGTGAACGTCCTTATCATTGTTTGGTGTGCGGCAAACGCTTTTTAACTGGCTCCGTTTTCTACCAGCATCGTCTTATACATCGTGGCGAACGACGTTATGAATGTGAAGAGTGTGGTAAACGTTTTTATCGTGCAGATGCACTTAAGAATCACCAACGAATACATACTGGTGAAAAACCATTTGGTTGCCTGTTTTGTACAAAGAATTTTCGTCAACGCGGCGATCGAGACAAGCATATAAGGGCTAGACATTCGCACCTGGATGCGAACGCGCGTTTAATgatgcaaatgcaaaaattacaGTTGGAAGCAGCGGCAGCTGCCGCTGCAGCTCAAGCAGTAGTTCAACAGCAGCATGCCAATAATGCTGCAATTAGTATGAGTGGCATACCCACTGTAACACCAACTCTTATGAGTATGCCGTCTGTAAGCAATGATGTAATTGATGGCCTAGAACCGTCATTAGATCCGAATGAAGTTGTTATGATCGGAAATGTAGCTTTTCCAAAAAGCATGTTTGAATCCATTATTCCGGACATTGATGAAGAGTCTGCACTTAGAGCCATGGAGCAGTTGCAATAG
Protein Sequence: MVNETVKQTTGSFDATEEELKLLQFLETQPQSSPLDTKLYIPPDVPPSAYRIVKCSNCNCLFDIISFQSHICDYDEHHNLIIPPAASTPINKPIKEEPLLPPEPACIRLLRENQIRIRRFLKDELKYDVNASINNNLNNSSSTLGNTSNTSTGSTSSNTASKKQDGPHECTLCERKFVHASGLLRHMEKHAMDLIPTPGASSGGKTTSSQCSSLQSVNGLRVVIKCTLCGRVFFEPFAAFKHLCSHFPGSMQEEKEFDNCAEIPYESYVDDAMNFLKMEINNCAGPLTVHGDKSPVYLKMVILSCILQCEFCDFVFSEVSYLFVHSACHLPERRFECFSCDIHMRTSKEICAHWQAECVFMRENLKVHQASTQRYFVCNVCENKFQSLDQLHEHRYTAYHFFPRLNKCLGVLQLPCEYCDVVFEFAQECVAHYEEKHYKKYKRDKDGTGSSSKTRQYLCDMCGKSYTQSSHLWQHLRFHQGVKPFACKEPGCTRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPFGCLFCTKNFRQRGDRDKHIRARHSHLDANARLMMQMQKLQLEAAAAAAAAQAVVQQQHANNAAISMSGIPTVTPTLMSMPSVSNDVIDGLEPSLDPNEVVMIGNVAFPKSMFESIIPDIDEESALRAMEQLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00081676;
90% Identity: iTF_01563225;
80% Identity: -