Basic Information

Gene Symbol
-
Assembly
GCA_000789215.2
Location
NW:156951-161319[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0031 0.17 11.9 5.8 1 23 137 160 137 160 0.97
2 10 0.048 2.7 8.1 0.2 1 23 168 191 168 191 0.94
3 10 1.3 76 3.6 6.2 1 23 255 278 255 278 0.96
4 10 0.0011 0.062 13.3 1.0 1 23 286 309 286 309 0.95
5 10 0.42 24 5.2 0.2 2 23 348 370 347 370 0.92
6 10 0.034 1.9 8.6 1.7 1 23 432 455 432 455 0.95
7 10 0.00091 0.052 13.5 0.9 1 23 463 486 463 486 0.95
8 10 9.5e-05 0.0054 16.6 1.0 3 23 547 567 546 568 0.94
9 10 0.0096 0.54 10.3 0.2 2 20 575 593 574 595 0.94
10 10 3.4e-05 0.0019 18.0 0.4 3 23 605 628 603 628 0.90

Sequence Information

Coding Sequence
ATGAGCATCAACCATGCTTTTTATattgatatgaatttttctaaaataatcgTGGTCAGAATGAAAACGTGCAAGTTGTGTAAAAGTAAATCCGAATCTGTTTTTGAGCCCAACGAATATATACTGGGCACACAAATTTCtgatgttataaaatttatatttagtgaTCAGTCGTTGGAGTTTCcaccaaaatttttcatatgttCTTCGTGTGCGGCGGCGTTGGTACAAACTGAAATTCTGCTAAAGAGACTTTCGGAGGCTTTGCCACACAGCAGAAATTCTGGGAAACTAAACTTATCCAATCATAAAAACGAAGATAACGATGAGGAGCCTCAGACCGAGCAGAatgatataaatgaaaatagcaaAGCTTCGGCATCTGAAACCTTTCTGAAGGATTGGATATTTCGCTGTACCCATTGCGATTACACTACCAGAAAGCCTAAATTGTACAAAACTCATTTAACAACTAAACATGAACTCAATAATCCACGCATTTACCAGTGTATGTATTGTTCGGAATCATATCAACGCATAAATGCCATACAAAATCACATCGGCAGCATACATGAAAATAAACCCCGTCAAAAACGTCAACGTCGAAAGACAATTGCATTTGATTCTCCAAGTGTATTGAGCAGTACAACCATCAGTAAACAGGTGGAAATTAACACTCCAGTTGGTAATGTCAACAATGAAACAAATGGTGTTGATACAAATAATGATAGTTATCAAGCAGATGGCAGCAAAAGCTATGAATTTACATGCAGTCACtgcatttataaaacaatatttccaaaacatttcAAGCGGCACTTATCAGTCAAACATAATATTGAAGACACAAGAATTTATAAGTGCAAGCGATGTTCTAGTACGTATGCACGACAATTTGCTTTGAATAACCATATCGCTTACGAACATGAAAACAAACCTAAACCACAACGCAGAAAGTCCGTAGCTTTAGAACAAAGTATATTATACAAAGACGAGTTAATAATACCTAAAGAAGAAATATTGGATGATAATGACGACCTAAGATGTGAACTTTGCCTTTATCAAGCGCAAGACTCAAAAACGCTTCGAAATCATATGGTAATATTACATCAAACTGATAGTCTaattcaaaacaataacaataatcaaaaggacaacaattataaaaataatgtctaTTCGGAGACCACTTCTGATAATCAAGAAGAACAGCAAGATCATGTATTCCAAGAACCTTTTAAAAAACCACGTAATCAATTAAGTTCGAGTGAAATATCATCTTCAGAATGGGTTTTCCAATGCCCACGTTGTGATTTTGAATGCGCCAAAAAGAAAGTATTCAAAGCTCATTTAATTAATGAACATGACTTATATGAAAGCGATATATACAAGTGTCTTTACTGTTCGTCAACATACGAACGTTATAGCTCGTTGCAGAATCATGTAGCAGTGAATCACAGCGTTGATTTGACCGGAATAGAATCGGATTCTAGTCAAGATAACGttgcaaagaaacaaaaacttaatGGAACTGCAAATAGTACAGAAAAACACACTCTTGAAAACAGCAGTCAGGAGCAAATGCCGTCAAAAAAACGTAAAATGGAACGAGAAGAAcgagaaaaaagtaaagaatctTGTGTTGTATGTGGCAAGCTTTTTTCCACCGTGGACAAATTGCGCGCTCATATGGACAAACATCATGGAGGCGATGAAATCAAAAAGTGTCCGAATTGTGATGCACAATTTCGTTCGTTGGAGAAGTACGAGGCACATCTGTTTAGTGAGAAATGTCTCAACACTAAGTTAGCCTGCCAATATCCAGGTTGTCCGAAACGTTTTAATAGACCatcaaaaatgcaacaacatatGCGTGAGAAACATCCCGATGTAATAGACTaa
Protein Sequence
MSINHAFYIDMNFSKIIVVRMKTCKLCKSKSESVFEPNEYILGTQISDVIKFIFSDQSLEFPPKFFICSSCAAALVQTEILLKRLSEALPHSRNSGKLNLSNHKNEDNDEEPQTEQNDINENSKASASETFLKDWIFRCTHCDYTTRKPKLYKTHLTTKHELNNPRIYQCMYCSESYQRINAIQNHIGSIHENKPRQKRQRRKTIAFDSPSVLSSTTISKQVEINTPVGNVNNETNGVDTNNDSYQADGSKSYEFTCSHCIYKTIFPKHFKRHLSVKHNIEDTRIYKCKRCSSTYARQFALNNHIAYEHENKPKPQRRKSVALEQSILYKDELIIPKEEILDDNDDLRCELCLYQAQDSKTLRNHMVILHQTDSLIQNNNNNQKDNNYKNNVYSETTSDNQEEQQDHVFQEPFKKPRNQLSSSEISSSEWVFQCPRCDFECAKKKVFKAHLINEHDLYESDIYKCLYCSSTYERYSSLQNHVAVNHSVDLTGIESDSSQDNVAKKQKLNGTANSTEKHTLENSSQEQMPSKKRKMEREEREKSKESCVVCGKLFSTVDKLRAHMDKHHGGDEIKKCPNCDAQFRSLEKYEAHLFSEKCLNTKLACQYPGCPKRFNRPSKMQQHMREKHPDVID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00190263;
90% Identity
iTF_00190263;
80% Identity
-