Basic Information

Gene Symbol
-
Assembly
GCA_000789215.2
Location
NW:437431-438896[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 0.00015 0.0086 16.0 0.2 1 21 139 159 139 160 0.97
2 6 5.1e-07 2.9e-05 23.8 0.8 2 23 174 195 174 195 0.98
3 6 0.0015 0.085 12.9 0.7 2 23 202 223 202 223 0.97
4 6 2.6 1.5e+02 2.7 1.0 1 11 250 260 250 262 0.92
5 6 0.00025 0.014 15.3 0.2 1 21 272 292 272 293 0.94
6 6 0.0022 0.13 12.3 1.3 1 20 300 319 300 319 0.96

Sequence Information

Coding Sequence
atgaACCCAAAGCGAGCCAAATTCACAACACTGACTTCAACGGTTAAAGAGGAAGTGGTTCCGGTACTGATTCATGATCCCAATGCTCCAGATGGTGCGCAATATGCATATGCGACATTTACCTCTGCGGAAGAATCTGAATCTGCGGTTGAATCATTGTCTGGAACACATGAAACGATTGTAAGCACACAAGAAGTGATAATTGATGAACATGGACGTGCTGTAACCATTCAGCAGCTAGTCGATAATCATTCTGTCGAAGAGGTGGAGACCGTGGAAGAAAACGATGGCACACATACCATTTTACATATTGTACCTTCATCGCCAATTCCCGAAGAGACGGGAACTGAAAGCGGTGGAGATGGTGATGCCAGCCTTAGCCCAACTGATTCGATGGGCAACCGTTCTAAGACTTTTTATTGCCCAAATTGTGGCAATTGCTACAGTGCTGCTGGGTCATTAAAACTACATATGCGCGCTTGTATGAAGCAGCGTGAAGAGGTTCCGCCAGAACAAAGAAAGTGTGAAATATGCAATAAGGTATTCAATTCAGTTTCGTATTTAAAAGAGCATATGATGCGACACACAGGGGAGGGCCCAAGACGATGTACTCGgtgttatagaaaatttattgacGAGGGTAAATGGAAAGCGCATATGGAGAGCCATAAACAACAAGATAAACTAGACGCGGAAGCTCAGGCTTTAGCTGAACAGCATGGAGGGAAAAAGATAGTGGTTAAAGAGTTCACATGCTCATTTTGTTCACAAAACTTTACGGTGGTATTCGAAGAAGGCCAAGTAAAACGGCGTTACGCCTGTGATGAGTGCCGTGAGAAGTATTCCAATGCGGAACAATTAAAACAGCACAAACAAATGTTAGGAGAGAAGCGCGATTTCCATTGCGAACGTTGTGGGCGCAAATTTGTATTTGAGGGTTTCTTGCAGAGACATCTTCCAACTTGTGATGGTACAATTAAACGACGACGGGACATGAAGTAA
Protein Sequence
MNPKRAKFTTLTSTVKEEVVPVLIHDPNAPDGAQYAYATFTSAEESESAVESLSGTHETIVSTQEVIIDEHGRAVTIQQLVDNHSVEEVETVEENDGTHTILHIVPSSPIPEETGTESGGDGDASLSPTDSMGNRSKTFYCPNCGNCYSAAGSLKLHMRACMKQREEVPPEQRKCEICNKVFNSVSYLKEHMMRHTGEGPRRCTRCYRKFIDEGKWKAHMESHKQQDKLDAEAQALAEQHGGKKIVVKEFTCSFCSQNFTVVFEEGQVKRRYACDECREKYSNAEQLKQHKQMLGEKRDFHCERCGRKFVFEGFLQRHLPTCDGTIKRRRDMK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01045805;
90% Identity
iTF_00091745;
80% Identity
iTF_00190262;