Basic Information

Insect: Automeris io
Gene Symbol: topi
Assembly: GCA_036320925.1
Location: JAUDJH010000024.1:8427965-8438956[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00072 0.055 14.6 0.5 1 23 343 365 343 365 0.99

2 12 0.023 1.7 9.9 5.7 2 23 373 394 372 395 0.94

3 12 0.43 33 5.9 0.2 1 23 399 421 399 421 0.96

4 12 0.047 3.6 8.9 1.5 1 23 426 449 426 449 0.95

5 12 0.0049 0.37 12.0 0.1 1 23 453 476 453 476 0.94

6 12 0.0017 0.13 13.5 0.2 2 21 494 513 494 518 0.92

7 12 0.021 1.6 10.0 0.5 3 23 528 549 528 549 0.98

8 12 2 1.5e+02 3.8 1.1 2 23 573 595 572 595 0.95

9 12 5.1e-07 3.9e-05 24.6 1.1 1 23 606 628 606 628 0.98

10 12 0.00051 0.039 15.1 4.7 1 23 634 656 634 656 0.98

11 12 0.0095 0.72 11.1 3.3 1 23 662 685 662 685 0.98

12 12 7.1e-06 0.00054 20.9 0.1 1 23 691 714 691 714 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00072	0.055	14.6	0.5	1	23	343	365	343	365	0.99
2	12	0.023	1.7	9.9	5.7	2	23	373	394	372	395	0.94
3	12	0.43	33	5.9	0.2	1	23	399	421	399	421	0.96
4	12	0.047	3.6	8.9	1.5	1	23	426	449	426	449	0.95
5	12	0.0049	0.37	12.0	0.1	1	23	453	476	453	476	0.94
6	12	0.0017	0.13	13.5	0.2	2	21	494	513	494	518	0.92
7	12	0.021	1.6	10.0	0.5	3	23	528	549	528	549	0.98
8	12	2	1.5e+02	3.8	1.1	2	23	573	595	572	595	0.95
9	12	5.1e-07	3.9e-05	24.6	1.1	1	23	606	628	606	628	0.98
10	12	0.00051	0.039	15.1	4.7	1	23	634	656	634	656	0.98
11	12	0.0095	0.72	11.1	3.3	1	23	662	685	662	685	0.98
12	12	7.1e-06	0.00054	20.9	0.1	1	23	691	714	691	714	0.97

Sequence Information

Coding Sequence: ATGGAGGAGACAAAAGTATGTAGAATATGTCTCGCAGTGGACGTTAAAATGTTTGATTTGCAAGAACAACCCTTAGAAGTTTATTTTGAACAGATAATTGGTGCACATACAGTGAGCATGATGGAGCTTCCACCATTTGCGTGTTTTGAATGTGCTGCTCTGGTGAAAAAGTACTATAACTTCAGGAAAAGATGTCTTCAGGGGGAATCAACTTTGATAGAGATTCTGTACTCAAATGgaaaaATAACAAGGGAAGCAATACAAAAAATAGATAGGACTCAGTTACATATAGCATCCAACTACACAATGCATACAGTATCTCAAGAAAACGTAATTTACTGTAATAATGATAAAGAGAGTGCTAATGAAATTAAGAAAGAAGAATCTACCACAGAAAGCAAATTCAAAATAGAAGACAGTGATGGAGATGATTGTTTTGATGATCTTCCATCACTGTCTACCACAGATAATGAATCACTATCATCACttgatgatattaaaacaaAGAGAACTAAAAAGAAAGTTAAAGGGAAGACAGCAAAAAAAATGAagttggaaaaaaaattaaaacttgaaGACAGTGATGAAGATGAAGACTTATTTGGTGAAGTTCCTATACTACCTTCCATGGATGATGTTGTATCAGTATCCTCATGCGATACTATTGAATTAATTAGACCTAGGAGGACAGtgaaaaagaaagcaaagaCAGGAAAGGGAATAAAGTTAGATGTCAAATCTGATGCGACTAAGCCATTGGGGAATCTTGAACTGGGTACAAGTGACGAAACAGTATTATCTGGAAAGTTAACagaaaaagtaaaacaaaaatcaaggaGAGTCCGTCCTAAGAAATCTGATATTCAAAAGGCAGCACAGAGGCCAAGGAGAACTGTCGGTCCTGATGAAGATCTCGTAAACAAAACTGACCTTTCGGAGTTTGTCACAATCATTAAATTGTCTGCAACAGAACAAATGGAGGAGCTGAACAAGAGACAGCAGTCCTCGAACTACCTCCACGCGCCGTATCAATGCAATTTGTGTTACAAAGGCTTCATTAATGTGGACGCATGGGAAAAGCATTCTCGTAAACACGATCAGAGCAGCGGGAATTTGGAGTGTAAGATTTGTAAGTTTCGATTTAAAATCCACCGGGATCTGAGGCAGCACATCACTAGGCATCACTTAATGAAGTATGCTTGTAAAGCGTGCCCGTACGTCTCATCCTCTACGAACCAAGCGAGACGGCATGAGAAATGGCATAGAGGTGTAACTTATACGTGTCAATACTGTGGAGAAGTTTCAACGAAATGGACCTCGCATCTCAGCCATGTCCGCATAAAACACCCGTCGGAATTCATTTGCGGTATCTGTGGATACTCATACGTCAGTGAACTCGGCCTGAGGCAACACAAAGCTATGATGCACAAAGATGAAGCTGATAAGGTCGAAGCAGATGAAGGCGCGGAAACCAGCGCGTACTGTGAAGTATGCGAGATCAAGTTCACATCGGCGGAGGCGTTCAACAGGCACATGGTCACCTCGGCTAAACATACAAAGATGAATTCGTTCGGCAGAGGATGCCGTATATGCGGCGAATGGTTCAAAACCCCGGAAGAATTGGGGTCACATCATCGCAAGGGGCATCCGGACAAATTTCCCAAGAAATCATATCATAAGCAACATTATCTTATAAATAACATGACCTGGCCAACTAAATGTGAACATTGCTCTGAAGTCATCATGAATGGCCGTGATTATTGGAATCATTTTCGGCGAGAACACCCCGATAAGAAATATCCTATAATTAAGAATTACATTTGTGACATTTGCGGAAAAAGCTTTAcgaacaaCACAACACTGGTGTACCATAAGCGTACGCATTTAGACGAGAAAGCCTTCAAATGCTCCACTTGCGGGAAAGCGTTCCACACGAAGGCTGGTCTCCACCTGCACAACAAGACCCACTCGGACGAGCGCCCTTACTCCTGCACCGAGTGCTCCAGGTCTTACAAATGCAAGGCTGCGTTTTCCAAACATATCAGAATAAATCACAGAGGATTAAAGCCGCATCAGTGCGATATTTGTGGGAAGGCTTTCGGAGAATCCAGTGGTCTGAAAGTCCACGTGATGACAGTGCATTACAAACAGCCCTATCAGCCGTACATCAGGCGAATCAGAATGAAGCGAGTGCACAAAACCCAGTACCAGAAGGATGATCCGCAACACTAG
Protein Sequence: MEETKVCRICLAVDVKMFDLQEQPLEVYFEQIIGAHTVSMMELPPFACFECAALVKKYYNFRKRCLQGESTLIEILYSNGKITREAIQKIDRTQLHIASNYTMHTVSQENVIYCNNDKESANEIKKEESTTESKFKIEDSDGDDCFDDLPSLSTTDNESLSSLDDIKTKRTKKKVKGKTAKKMKLEKKLKLEDSDEDEDLFGEVPILPSMDDVVSVSSCDTIELIRPRRTVKKKAKTGKGIKLDVKSDATKPLGNLELGTSDETVLSGKLTEKVKQKSRRVRPKKSDIQKAAQRPRRTVGPDEDLVNKTDLSEFVTIIKLSATEQMEELNKRQQSSNYLHAPYQCNLCYKGFINVDAWEKHSRKHDQSSGNLECKICKFRFKIHRDLRQHITRHHLMKYACKACPYVSSSTNQARRHEKWHRGVTYTCQYCGEVSTKWTSHLSHVRIKHPSEFICGICGYSYVSELGLRQHKAMMHKDEADKVEADEGAETSAYCEVCEIKFTSAEAFNRHMVTSAKHTKMNSFGRGCRICGEWFKTPEELGSHHRKGHPDKFPKKSYHKQHYLINNMTWPTKCEHCSEVIMNGRDYWNHFRREHPDKKYPIIKNYICDICGKSFTNNTTLVYHKRTHLDEKAFKCSTCGKAFHTKAGLHLHNKTHSDERPYSCTECSRSYKCKAAFSKHIRINHRGLKPHQCDICGKAFGESSGLKVHVMTVHYKQPYQPYIRRIRMKRVHKTQYQKDDPQH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -