Basic Information

Insect: Autographa gamma
Gene Symbol: THAP3
Assembly: GCA_905146925.1
Location: LR989879.1:2916626-2931566[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.31 29 5.9 1.3 1 23 355 377 355 377 0.92

2 11 0.0017 0.16 13.1 1.2 1 23 384 407 384 407 0.93

3 11 0.25 23 6.2 0.2 1 23 411 433 411 433 0.92

4 11 0.035 3.2 8.9 1.0 1 23 438 461 438 461 0.98

5 11 0.0025 0.22 12.6 0.7 1 23 465 488 465 488 0.96

6 11 3 2.8e+02 2.8 0.1 2 19 501 518 501 521 0.78

7 11 0.14 13 7.0 0.2 3 23 576 597 574 597 0.95

8 11 0.0036 0.33 12.0 0.6 2 20 613 631 612 634 0.92

9 11 2.6e-05 0.0023 18.8 3.0 1 23 640 662 640 662 0.99

10 11 0.00021 0.019 15.9 2.8 1 23 669 691 669 691 0.98

11 11 0.0033 0.3 12.2 4.9 1 23 697 720 697 720 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.31	29	5.9	1.3	1	23	355	377	355	377	0.92
2	11	0.0017	0.16	13.1	1.2	1	23	384	407	384	407	0.93
3	11	0.25	23	6.2	0.2	1	23	411	433	411	433	0.92
4	11	0.035	3.2	8.9	1.0	1	23	438	461	438	461	0.98
5	11	0.0025	0.22	12.6	0.7	1	23	465	488	465	488	0.96
6	11	3	2.8e+02	2.8	0.1	2	19	501	518	501	521	0.78
7	11	0.14	13	7.0	0.2	3	23	576	597	574	597	0.95
8	11	0.0036	0.33	12.0	0.6	2	20	613	631	612	634	0.92
9	11	2.6e-05	0.0023	18.8	3.0	1	23	640	662	640	662	0.99
10	11	0.00021	0.019	15.9	2.8	1	23	669	691	669	691	0.98
11	11	0.0033	0.3	12.2	4.9	1	23	697	720	697	720	0.90

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTCAGAATTGTTGTAATGATACGAAGAAAACCACAAAAAGCCATGGAATTACATTTCACATGTTTCCTAAAGAACCAAATCTCCGTACAGCATGGGTGGAAGCCTTAGGCATGTCTGATTGGGAGCCCAAAGACAGAAGCACGATATGTTCTGAACATTTCAGGAATGAAGATTTTTATGAGACTAAGCGTGGTCTCCGTAAGATAAAGAATGGAGCAGTTCCTGTTGTTGAGCAGGATTCTTCTGATGACTTGGATGCGCCGGCCGCATTACGAGTATGTAGGATATGCCTAGATATGGACACGAAAATGTATCACATAAGGGAATTTAAATTGGATCAAATGTATGAACAAGTTACTGGCCTTTTGGCTAGTAGTGAGGAGCGTCTACCCCAGCGGGTATGCTGGGAGTGCGGCGCGCGTCTCACGGCTGCTGTCGCCTTCAGGAACAAGGCGCTACGGAGCCACGCTTTGCTACAAGATATGCTGCTACCTGACACATATATCAAAATAAGAGACATAAAATCAATAAACCGAAGTCACAACGCCTTAAAAACATCGCTCATACAAAAGATATTTGACAATACCGACTACGATTTACACATTAACGACGACTCAGTCAAATCCGAACAGAATCTAGATCTAGATTCAGAAGAGAGAGAAAATCTAGAAATTGAAGTCAAAGACCTAGTTCCTATAACTGAAATAGAAGTTAAGGATGAGACTGTTAACGAAATATTCTTTGAAGAGTATGACAATTATGACGATGAAGATGATAGAGCGTTGAGTGATGTTTATGGGGAGAAAAAGGAAAAGATTAAAGTTAAGAAGAAGAAAGAAAAGATTGTTAAGAAGGTTAAGCCGAAGAAGGTTGATGAAGATGAAGACCCTGAGTCTACTACTGATAAATACAAGAAAAACGGTGTAAAACGCAGGCGAGGGAACGAAGCGTTCGACGGTACATTATTCACGATCACTTCACTCTCGTACGAGCAACAGATCGAAGAGGTCAGCAAGCGACAGGAGAGTGCAAGCTATAGCGCCGCGCCATACAAGTGCACTGTCTGCTATAGAGGGTTCCAGATCAAAGACAGATATACTGCACATTCTGTGAGGCATAGCGAGCAAAGCGGTGCCTACGAGTGTTTTATATGTAAGACTCGGTTGAAGACCAGTCGCGCGCTACGGAAGCACTTGACTGCGCAGCATACTGAACAATATAGTTGTAAGGGATGTCCGTTTGTCACTAGAAATAGAGGAGTAGCAAGAGAACATGAGAAATGGCATGCTGGCACGAAATACCAGTGTCCTCATTGTGCGAGCGAGTTTGAAAAACTAACAACGTACATGGGTCATATAAGAATAAAACACGTATCGGATTTCGTTTGCGAGCTTTGTGGCTATACGTTCGTCAGTAAGAAAGGGATAGACGTACACAAGAAGAAGAAACATCGACTTGTTGATAAAGCTGTAACATTAGAAGGTCCTTATTGTGAGGTGTGCGATGTGAAGTTCGTGTCAGAAGAAGCACATGACAGACACCTGAAGTTATCTTCAAGACATAGCAGTGACCATGATCCGAATCGCATAAGAAACGACTCGCAGAGCATGAACACGGAACGCAACGGGCGCGTGATGAGAAGGATAGAGCGCCGGCCTGTCATACACCCGCGGGATCCCACCGACACTCACGATACACACGCGCCTATCAACTGTGAACAGTGTGGCATCCAACTACGAGATTTACGGTTATACGCGCAACACTTCAGGCGAGCTCACCCAGACAAGAACCGAACCAAGTACCCCGCGATGAAAACCCCTTGTATGTGTGAGCAGTGCGGCAAGATATTCCAGAGTATGGCCCTCCTAAAAGACCATATGTGGGTGCACACGGGCGAGAAGCGTTTCAAATGCGACCGCTGCTCAAAGAGCTTCACTCAGAAGACGAACCTGGTCTTCCACATGAGAGTACATAGTGCTACGCGACCGACCTACGAGTGTCCGCTCTGCGGGAAACACTTTGCGTTCTTCAATAATAGGAGGAGGCATATGTTTATACACACCGGCCTGAAACCGTTTAAATGTGACACTTGCGGCAAATGTTTCACGACATCGGGCGAGCATAGAGCTCATGTAGAGCATGTGCATCTAAAGAAACCGTGGCCAAAACGGGCTAGGCAGAGAGGTAGGGACTGGAAGTGCGATGTGCCTAGTGTTGAGGACTGA
Protein Sequence: MRCSVQNCCNDTKKTTKSHGITFHMFPKEPNLRTAWVEALGMSDWEPKDRSTICSEHFRNEDFYETKRGLRKIKNGAVPVVEQDSSDDLDAPAALRVCRICLDMDTKMYHIREFKLDQMYEQVTGLLASSEERLPQRVCWECGARLTAAVAFRNKALRSHALLQDMLLPDTYIKIRDIKSINRSHNALKTSLIQKIFDNTDYDLHINDDSVKSEQNLDLDSEERENLEIEVKDLVPITEIEVKDETVNEIFFEEYDNYDDEDDRALSDVYGEKKEKIKVKKKKEKIVKKVKPKKVDEDEDPESTTDKYKKNGVKRRRGNEAFDGTLFTITSLSYEQQIEEVSKRQESASYSAAPYKCTVCYRGFQIKDRYTAHSVRHSEQSGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCASEFEKLTTYMGHIRIKHVSDFVCELCGYTFVSKKGIDVHKKKKHRLVDKAVTLEGPYCEVCDVKFVSEEAHDRHLKLSSRHSSDHDPNRIRNDSQSMNTERNGRVMRRIERRPVIHPRDPTDTHDTHAPINCEQCGIQLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCSKSFTQKTNLVFHMRVHSATRPTYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTSGEHRAHVEHVHLKKPWPKRARQRGRDWKCDVPSVED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00450559;
90% Identity: iTF_00186308; iTF_00186651; iTF_00185376; iTF_01221642; iTF_01222020;
80% Identity: iTF_00185376;