Basic Information

Insect: Autographa gamma
Gene Symbol: ZNF219
Assembly: GCA_905146925.1
Location: LR989855.1:834974-842919[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0022 0.2 12.7 3.2 1 23 397 420 397 420 0.95

2 7 1.1e-05 0.001 19.9 0.8 1 23 682 704 682 704 0.98

3 7 0.00012 0.011 16.7 0.7 1 23 709 731 709 731 0.97

4 7 6.3e-06 0.00057 20.7 0.4 1 22 737 758 737 760 0.90

5 7 3.9e-07 3.5e-05 24.5 1.4 1 23 766 788 766 788 0.99

6 7 1.3e-05 0.0012 19.7 3.3 1 23 794 816 794 816 0.99

7 7 2.1e-06 0.00019 22.2 3.4 1 23 822 844 822 844 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0022	0.2	12.7	3.2	1	23	397	420	397	420	0.95
2	7	1.1e-05	0.001	19.9	0.8	1	23	682	704	682	704	0.98
3	7	0.00012	0.011	16.7	0.7	1	23	709	731	709	731	0.97
4	7	6.3e-06	0.00057	20.7	0.4	1	22	737	758	737	760	0.90
5	7	3.9e-07	3.5e-05	24.5	1.4	1	23	766	788	766	788	0.99
6	7	1.3e-05	0.0012	19.7	3.3	1	23	794	816	794	816	0.99
7	7	2.1e-06	0.00019	22.2	3.4	1	23	822	844	822	844	0.98

Sequence Information

Coding Sequence: ATGGATGAAGCTGTAACGCATTATATTAATTCTCACCAATCTGACGAGGCGGTTCATGTGGACGCGAACGCTTTGGCGCTGAACGTCCAGGACGATGGCGGAGGCAGGGTGGCTATCCTGCACTCTCAGACATTTTCCACATCAATGTGCAGGCAGGTATCAGTGGGAGACCAAGTGGAGGGTCCATGGGGTGAAGAGCTGATGGATCCCGAGGGCCGGCTGGCCGCGCTCATGGCGCACATCACGGCGCAGCAGGCCAGGGCGCCGCATCCACAGCAGCAACACCTCAAGGTGCAGACCGTGAGGGGTGATGTGGACACATCAATCATACTGGATAGTTCCATGAGACTGTTTCACGGACCACCTATGGACCAGAATCAAGAGTCAATTATTGTAGAGGTACCGCCTCTCCCTCCCCTGCCTCCACTACAGAACATGAAAAGATGTCCAGAGACTGAAGACTGGTTTGACAACAACAAGGCTCCTAAACCAAATCTCAAAGATGATTCCATGGTGGATTCTGACGGCCCAGTACTAGAGCTCGGTGCCGCCTCCTCTCCCGGACACAACAAGCTCCAGAGCAAGAAGAGTCTCCCACACAAGAAGAGAATATCCAGAAAGCTTAGGAAGAATAACGGGAACATGACTCCGCAACAGGAGCTGGTGGTGATCAGCTGCACGGACGTGAACGGTCGCATCAGCTGCTCGGAGCACGCGCCCGAGGAGGAGATCCTGCCCGACAACTACGTGCAGCAGGAACACATCGCTGATGACGCGCATCATATTACGCATGAGGTCCGTCCAATCTTCATCTGCCAGCTGTGCGGCGAGTTCTACGGCGAGGAGCAGCTGAAGTTCTACCAGCACCTCAAGCAGCACTACGAGCCGCACATCATCATCGAGAACCCCGTGCCAGAGCTGGCCATGGATAAGATGACGAACTCCTGCATAGTAGACAACGTAACAACAATACCAGACTCCATAGTTGAACTGTCCCTAGAGAATTCTATACCAAAAACTATTTACCAGTCGATAGACAAACACGTATTATACACCACAAGCGATAAGACGCTTACGTACGGTAGCAATAAGCTCCAATATTCCATGGCGAGTATGGACAAGGAGCCGACGGTAGTTGCTGAGGCGGAGAAGGCGGATTTGTACGATACCTTAGATAAATTGGATCTGTTCAGCTGTGGGAAGTGTAATAAGTCATTCAGGAAACAGAAGCAGTGTGAGGCGCATATCAAGGAGGCGCATTCGAATATGAAGCTGGAGGACATGGGCGAGTTCAGCGAGCCGGAGGACCTGATGGAGGGCATCCACGTGGCCGTGGACGAGCCAACAGAACACTACGAGCACACGCTGCTGCCGCACCTCACCGTCGAGAACGGACACGCGCACCAGGACAACAGGCACTGGTACGTGCGCAGTAACGGCGGGCCGAATAGTCCGGTAGGGGGCGCGAGCGCGGGCGGGGGCGCAGTGTCTGGAGGTGGGGGCGCGGGGGGCGCGTGCCCGCCATACTGCGGCGTGTGCGCGGGCGCAGCACGGGAGAGAGAACACGACCACAACCATCTCAAAGCACTCAATCCTAGAAAGATTACCATGCTGCAAGAAGAGGTTTTGCAACGTTTCTTAGACACGGATGTAGCGAACGACGGCGGCAGCTTCCCCGACAGCATGCTGCCGCCGCACCCCGCGCCCCTCCCGCCCGACACGCACACACACGCACAACACACCATACAGACACACCACTCCACACACCACGCCACACCCACACCGCTAGAGACACAACCACCACACATATCGCAGGCACCGCAAGCAACGCATACGTCACAACCGTCGCACGCACCACCAACTTCGCACGCGCCGCCGACGTCGCTCGCATCGCAGACATCGCACGTGTCGCACGCATCGCAGACGCCGCACATATCGCACGAGCACATCAAACCAACACAAGCGTTGGCGGCCGACAGCAACAGTCCCGAGGCGGGCGAGGGTGTGGAAGTGAAGCAGGAGCCGAAGAAGAAGCAGAAGCGCTTCGAGTGCCCGCAGTGCGGGCGCGTGTTCGCGCACCGCAACAGTCTGCTCTACCACCTGCTGTCGCACAGCGGCAAGCAGCACATGTGCCGAGAATGCGGGAAGGGATTCTATACCGTCGCCGCGCTTAAGATCCACAAGCGCGTGCACAACGGCGACCGGCCGTACAAGTGCGAGGTATGCGGCCGCGAGTTCCGCCAGTGGAGCGACCTCAAGTACCACAACGTGTCCATACATTCCGACCAGAAAATGTTCAAATGCGAGTTCTGCGGCAAGGAGTTCGCGCGCAAGTACTCTCTGAACGTGCACCGGCGCATCCACACGGGCGAGCGCAACTACAAGTGCGAGTACTGCAACAAGACCTTCCGGGCCTCCTCCTATCGCCTCAGCCATATGCGGACACATACCGGTGACAAACCACACAAGTGCTCACAGTGTGACAAGTGCTTCCGCGTGGCCGGTGACCTGCGCCGGCACATGCTCGTGCACGACAAGGTGCGCAACCGACTCAACGAGCAGAAATCCAAGCCCAAAGATCAGAAGGACACCAAGAAACCACCCGAAAAACCCGAAGAAAAAGAAAAAGTTAAAATAGAAATCATATCCAAAGCTGGGAAGAAAACTGGGCCCGCATCCACTAGCATATTGTCCACGATCCTCAGTAGTTCAGCAAAGAAAACACCAAAGGCCGCCAAGAAGGCGCCGAGCTTAAGGAAGGGCGCCCCCAACGTCACCATCGACCAGATCGACGACAGCTACACCAACAATGTGGAGGTGTTCGACACGCGGCCAGACCCGCACTACGCCAAGTACAAGGACGTCTACCACGACGGCGCCTACATCAAGGACGAGCTCGACAACCACTTCTCCAAACAAATCATAGGCTATAAGGAAGAGCCCTCGGAAGAACGAGATCTCGCGATTCTACGGCCGATGTTCAGGAATAATGTGTTGTGTGAAAGTGTGGAGACGGACAAGACAGTGTATAGGACAGAGAACACGGACGGTAAGATGCAAGTGTACACGCACGTGGAGAAGAGCAAGGAGTTCGGGCTGGCGCCGGCCGCCGCGCTCGCCGACATGCGCCACCTGGAGCGCGACGTGCGCGACCTGCCCGAGACCATCGAGAACGGCTTCATAGAGAGACTCACGGCGCTCTACAATATACCTGCTGTGTGA
Protein Sequence: MDEAVTHYINSHQSDEAVHVDANALALNVQDDGGGRVAILHSQTFSTSMCRQVSVGDQVEGPWGEELMDPEGRLAALMAHITAQQARAPHPQQQHLKVQTVRGDVDTSIILDSSMRLFHGPPMDQNQESIIVEVPPLPPLPPLQNMKRCPETEDWFDNNKAPKPNLKDDSMVDSDGPVLELGAASSPGHNKLQSKKSLPHKKRISRKLRKNNGNMTPQQELVVISCTDVNGRISCSEHAPEEEILPDNYVQQEHIADDAHHITHEVRPIFICQLCGEFYGEEQLKFYQHLKQHYEPHIIIENPVPELAMDKMTNSCIVDNVTTIPDSIVELSLENSIPKTIYQSIDKHVLYTTSDKTLTYGSNKLQYSMASMDKEPTVVAEAEKADLYDTLDKLDLFSCGKCNKSFRKQKQCEAHIKEAHSNMKLEDMGEFSEPEDLMEGIHVAVDEPTEHYEHTLLPHLTVENGHAHQDNRHWYVRSNGGPNSPVGGASAGGGAVSGGGGAGGACPPYCGVCAGAAREREHDHNHLKALNPRKITMLQEEVLQRFLDTDVANDGGSFPDSMLPPHPAPLPPDTHTHAQHTIQTHHSTHHATPTPLETQPPHISQAPQATHTSQPSHAPPTSHAPPTSLASQTSHVSHASQTPHISHEHIKPTQALAADSNSPEAGEGVEVKQEPKKKQKRFECPQCGRVFAHRNSLLYHLLSHSGKQHMCRECGKGFYTVAALKIHKRVHNGDRPYKCEVCGREFRQWSDLKYHNVSIHSDQKMFKCEFCGKEFARKYSLNVHRRIHTGERNYKCEYCNKTFRASSYRLSHMRTHTGDKPHKCSQCDKCFRVAGDLRRHMLVHDKVRNRLNEQKSKPKDQKDTKKPPEKPEEKEKVKIEIISKAGKKTGPASTSILSTILSSSAKKTPKAAKKAPSLRKGAPNVTIDQIDDSYTNNVEVFDTRPDPHYAKYKDVYHDGAYIKDELDNHFSKQIIGYKEEPSEERDLAILRPMFRNNVLCESVETDKTVYRTENTDGKMQVYTHVEKSKEFGLAPAAALADMRHLERDVRDLPETIENGFIERLTALYNIPAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00186618;
90% Identity: iTF_00186618;
80% Identity: -