Agaa022438.1
Basic Information
- Insect
- Autographa gamma
- Gene Symbol
- Zfy1
- Assembly
- GCA_905146925.1
- Location
- LR989876.1:7147702-7153471[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.00012 0.011 16.7 4.5 1 21 109 129 109 130 0.93 2 17 0.19 18 6.6 1.5 2 23 162 184 161 184 0.93 3 17 0.025 2.2 9.4 1.3 1 23 189 211 189 211 0.93 4 17 6.5e-05 0.0059 17.5 0.9 1 23 249 272 249 272 0.93 5 17 2.3e-05 0.0021 18.9 1.4 1 23 278 300 278 300 0.97 6 17 2.2 2e+02 3.3 0.3 5 23 310 328 308 328 0.95 7 17 2.3 2.1e+02 3.2 1.8 1 23 334 357 334 357 0.90 8 17 0.0062 0.56 11.3 1.2 2 22 483 503 482 506 0.89 9 17 0.082 7.5 7.8 0.0 3 23 510 531 509 531 0.95 10 17 0.0086 0.78 10.9 1.4 1 23 536 559 536 559 0.95 11 17 7.3e-05 0.0067 17.4 1.6 2 23 565 586 564 586 0.96 12 17 0.78 71 4.7 1.2 2 20 590 608 590 610 0.91 13 17 2.5e-06 0.00022 22.0 1.2 1 23 636 659 636 659 0.95 14 17 0.00025 0.022 15.7 0.5 1 23 665 687 665 687 0.95 15 17 0.055 5 8.3 0.1 1 23 693 715 693 715 0.97 16 17 0.0029 0.26 12.4 0.3 1 23 721 744 721 744 0.94 17 17 9.9e-05 0.009 17.0 0.9 2 23 751 773 750 773 0.95
Sequence Information
- Coding Sequence
- ATGGAGGTCGACCCCGCCCTGCCCTGCGGCTTGTGCAGGCGTTGCTCCGACGACGCCATAGCGGCCTACACCTTCCGGAGCCTCTGTGCCCAGTCTGCCCACCACTGGAGAGAAGGAACCACCACCCTCTCCGACATCTATCCCCCCACGCAAGAAGACAAGGCATATTTCATCTTCTATCAAAAAGAAAACACAGTTATCAAAGACCAAATCGCTAGAGTACCCACGTTGAAAGACGCTATCGATAGACTAAACGATGGCTTTGTTACCAGGAAACCAGAGAAGAAGAAGAGGGCCAAATACTCGCATGGTCACCAAACAGCCTGCAAGTGTCCCGACTGCGGGAAAAAGTTCTCCAAACCGTACTTTTTGAATCATCATTTTAGGAACACCCTTAATAGAGTCTGCACGCATTGCTGCGCTATCATACCGAAGAAGAGGCTAGCGAAACACTTGGAAGCGCATCACAACTTCATCGTATCCGAATGCACTTTCTGTCATAAGCTCTTTAAAGAGGAACAAAATATGTTGGAACATGTGAATGAGTATCACGGGCCTAACACACACAACTGCAATGTGTGTGGCAACGGGTACACCAGCGAGAGGGCGCTGAAGTCCCACGCTCACGCCCATTCCTTGTTCCATTGTTCTTCCTGCACTTTAAGCTATGAGAATATAAAATGTTATAAGTACCATCAGAAAGTGTGTAAAGGGAACGGTCGGCAGCCAGTTGAATTCCAATCCTTTACTTGTCACGACTGTGGCGTCACTTACGATCGGAAACCTTCATTAAGAATACATATAGTCCAAAAACATCTTAATGTTCTACCATACACATGCCAGATTTGCGGTAAGCGCACATCGACTTTAGCTCATTTAAAATCGCACGAGAGCATCCATAAAACTGAACGCAAAATCTTCCAATGCTACTGCGGCGCTAAATTAAGAACGGAATTAGGTTTCCAGCTACATTTAAGGATTCATACGGGAGAAAGGCCTTATGAATGTGGTCACTGCGGAGACAGGTTCCTCTCATCATCCCGAAGACTTGACCATATAAAACGGAGGCATCAGGGAGCTAAAGACTTTAAGCACGGCTGCAAGGAGTGTTCGGCCAGATTTATGAAAGAAGAACCCCTAATACCAATCGGGGCGTGCGTCGCTTGCGCCAGCACAGCCCTAGCCGCGCAAGAGTTCAGAGTCTTCGTCAGAAACTCGCAAAAGCTTTGGCGGAAAGCCATCATCAATCTCGCGGCGTTGCCCACTTCAGCCACGCCGCCCGTCAAGTCAGTCTGCGCGTTCGTCAAAGAATCTGACCTCTCGATACAAACATTCAAAGATTACACCAATAGCGACCCAAAAACGATTCTCAATCGATTAAAAAATCGAGTAACTAAAAAGACTGTTGATCGGAAACCTAGAGGGGCTCGCACGGGACCGTCCTGCAGCTGTCCCGACTGCAGAAAAGGTTTCTTAAGTCCGTATTACTTGAATATGCATTTACGGAACAGTGGACATAAGGAGGCATGCTTAATATGTGGCTCTGTCTTCGTGAGAGGGAAAGAGATGCAAGAACATCTGTCGTCGGTACACAACGAGACAGCTTATCTTTGCAAAAAATGTCCTATTTTATGTACAACTGAGGCTTTGCTCAAGAAACATGTGAAGAAAGCTCACAGTGCCGGGGCGTTAACCTGCTCAGACTGTGGCAGGACCTTCCCCAGGCACGCATCCTTCGAAACCCACTCACAAATGCACGCAGTAAGAACCTGCAGGGCTTGTGGGGTCCAGTTCACAAACCGAGGCTGTTACAGAGAACACAGGTCTCAGTGTGAGCCAGACGCTAAGCCCAACGCTCAGACCGTCCCTCGAAATAGACGCTCCAACATCAGAGACCCAGCCACTTTCACGTGCGATCACTGCGGCAAGACATACAACTCTAGACCACAACTCAAAAACCACATACTATGGATACACATGGACATACGACCACATCAATGTCAATGGTGTGGAAAAAGGTTTTACACTCCGGCGCGACTGGCTGAACACACAGTCGTACACACCCGCGTTCGAAACTTCGAATGTGACATTTGTGGCGCGAAACTCGTATCCAAAATGGCCGCGGTTTACCATCGACGACGACATACGGGCGAAAGGCCGTATGAGTGTGAAGATTGTGGGGAAAAGTTCATTTCTGCGTCGCGTAGATCGGAGCACGCTAAACGCAGGCATAATAAAGGTTTTCGGTTGCCTTGCATGAAGTGTCCCGCCAATTTTGTTAGGAAACATGAGCTGAAGAAGCATATGGAAAAGGCGCATAGACAGGAAAATGTTTTAGGTTGGCCGTGA
- Protein Sequence
- MEVDPALPCGLCRRCSDDAIAAYTFRSLCAQSAHHWREGTTTLSDIYPPTQEDKAYFIFYQKENTVIKDQIARVPTLKDAIDRLNDGFVTRKPEKKKRAKYSHGHQTACKCPDCGKKFSKPYFLNHHFRNTLNRVCTHCCAIIPKKRLAKHLEAHHNFIVSECTFCHKLFKEEQNMLEHVNEYHGPNTHNCNVCGNGYTSERALKSHAHAHSLFHCSSCTLSYENIKCYKYHQKVCKGNGRQPVEFQSFTCHDCGVTYDRKPSLRIHIVQKHLNVLPYTCQICGKRTSTLAHLKSHESIHKTERKIFQCYCGAKLRTELGFQLHLRIHTGERPYECGHCGDRFLSSSRRLDHIKRRHQGAKDFKHGCKECSARFMKEEPLIPIGACVACASTALAAQEFRVFVRNSQKLWRKAIINLAALPTSATPPVKSVCAFVKESDLSIQTFKDYTNSDPKTILNRLKNRVTKKTVDRKPRGARTGPSCSCPDCRKGFLSPYYLNMHLRNSGHKEACLICGSVFVRGKEMQEHLSSVHNETAYLCKKCPILCTTEALLKKHVKKAHSAGALTCSDCGRTFPRHASFETHSQMHAVRTCRACGVQFTNRGCYREHRSQCEPDAKPNAQTVPRNRRSNIRDPATFTCDHCGKTYNSRPQLKNHILWIHMDIRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICGAKLVSKMAAVYHRRRHTGERPYECEDCGEKFISASRRSEHAKRRHNKGFRLPCMKCPANFVRKHELKKHMEKAHRQENVLGWP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00327298;
- 90% Identity
- -
- 80% Identity
- -