Basic Information

Gene Symbol
-
Assembly
GCA_028453695.1
Location
CM052104.1:9509465-9516378[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 1.8e-05 0.0013 18.9 0.9 1 23 356 379 356 379 0.97
2 8 0.003 0.21 11.9 1.2 1 23 396 418 396 418 0.97
3 8 4.9e-05 0.0034 17.6 1.5 1 23 441 463 441 463 0.97
4 8 0.0072 0.51 10.7 3.2 1 23 471 493 471 493 0.98
5 8 0.0011 0.078 13.3 0.3 1 23 534 556 534 556 0.97
6 8 6.7e-06 0.00047 20.3 0.8 2 23 562 583 561 583 0.97
7 8 4.9e-07 3.4e-05 23.9 0.7 1 23 589 611 589 611 0.95
8 8 7.3e-05 0.0052 17.0 0.5 1 23 617 639 617 639 0.98

Sequence Information

Coding Sequence
ATGTCCTCCCTCGATTATCTGGACCTGTGTCGGCTGTGTCTCGTGAAGGACCGTGTTTCGGTGCCGATTTTCGGGGGCGAGGGAAACGATCTTTTTCTGAAGATCGCCGCCTGTCTACCGGTCAAGGTCGGAAGGGAAGACAAGCTACCCAAGAAAATATGCGACGACTGTGTGTATAAAGTAGAATTATTATATGAATTTTGGAATACAACAGCGAACGCTGAAAAGCGACTATTACAATGGCTGGGAGAAGTCAATGTCGAAAGCGGCAAACAGGGTTATGTTCCCAATGTACTCAATCCGAATGTGATGAAACAAGAACAGAGTACAGAGAACAGGTTAGATGGCAGTGTGATGCAGCAAGTGGGAGAGCATCAAAACAATATGGGCATGAGTATGATGGACAACATGGGCCTCGGTATCCCTATGATGATACCCAACACTAATCAACAGCAACAACAAATAACCTCAGTTCCTATGGACACAAGTGGCAGTCCTGCGCAAAATGTTCAAGCAGTGCCTGGTCCGAGTTCACAAACTACGCATAACCAAATATCACAAAATCAAACCAGCTCGACGCAGCAAGAAGATGAAGAAGAGAGTAGCGAAGACGATGACAATTCTGACGACGAGTGTGACGGAGATGAAGGCCTACCTGTAAAAGAAGAGAGCGAAGAAGACCCAAACAGTAGAACTATAGAACCTACAACCTTTGTAAATGTTTCTTTGGCGTGTGACGAGGCGGGTCCTTCAGGGTTGCAACAGCAGAAAATGACAGACATGCCTGAGATGCCAATATCACAGTCAGCAGACGGGGATCCCAAAACTGGGGAAGGCAGCGAGACGTTTGGCGGATTGTCGGGGATGCTGCGTCAAATACTGTCGCCGTCACCCGAGACCGGGGACCCCGGTTTGCCTCTCAGTTGTACCCTACTTCAGAACAGCTCCATGTTCACGAACCAATCGTCGATGATGCAGTCGACGTTCCAGACCGTCCCGTCCCACATACCATCCATTTGCTCCGACCAAAACCTGTTGGACCACGTGCAGATTGTCGTCGAATCCCATCCGTGTCCCACTTGCGGCCTCGAGTTTCGAAGTGCCCTAAAGCTGAATTACCACATGAGAACGAGCCACGTGGTGATGCCGGAATTCGAGCACAACCTAGAAAACAACCCGGTGAGATACTCGTGCGCCGTCTGCTCGCGAAGCTTCTTCGCCCTGAGCCACCTGCGGATGCACGAGGTCACGCATACCGCGCCGGTGACCTCTTGCCCGCCGATGTCGACGATGTCAGCCGCAGCGAGCGTCGAGAAAACGTTCGCCTGCGATCGTTGCCAAGCCAGTTTCCGGTACCGTACGCTCCTCGAGCGGCATCGAAGGATGCACGAGGTCGGCCAGGAGAAGCCTTATTCCTGCCCTAGGTGTCTGATGCGGTTCGAGACGCGAAACTTGTACAATCATCACGCGAAAACCCACAAACCGATCCTGACGGGTAACGATAGAATCACCGACACGTCCATGGTGTCTTCCGGTGATCCGGTCACCAGCAGTATTACCGGTAACATTGTCGCGCCGCAGAACAAGTCGATCGCCTCGTATCCGtgcgactcctgctcgaaacagttcgccagcatggagtccctgaccacccacaaggctgtgcacaggtccagatctctcgtctgcgacgtctgtggcaaggggttcacgcatcgcaagtattacgtggtgcatcagcgcatccacaccggggaaagaccgtatctttgtgccatgtgcggaaagtcattcactcaggcctccactttaaccgtccatcgccggtatcacactggcgaacgaccttatacctgccccctgtgcggtaaaggattcgtcaccagaaccatcatgcttaaccacatgAAAAAGCATTGA
Protein Sequence
MSSLDYLDLCRLCLVKDRVSVPIFGGEGNDLFLKIAACLPVKVGREDKLPKKICDDCVYKVELLYEFWNTTANAEKRLLQWLGEVNVESGKQGYVPNVLNPNVMKQEQSTENRLDGSVMQQVGEHQNNMGMSMMDNMGLGIPMMIPNTNQQQQQITSVPMDTSGSPAQNVQAVPGPSSQTTHNQISQNQTSSTQQEDEEESSEDDDNSDDECDGDEGLPVKEESEEDPNSRTIEPTTFVNVSLACDEAGPSGLQQQKMTDMPEMPISQSADGDPKTGEGSETFGGLSGMLRQILSPSPETGDPGLPLSCTLLQNSSMFTNQSSMMQSTFQTVPSHIPSICSDQNLLDHVQIVVESHPCPTCGLEFRSALKLNYHMRTSHVVMPEFEHNLENNPVRYSCAVCSRSFFALSHLRMHEVTHTAPVTSCPPMSTMSAAASVEKTFACDRCQASFRYRTLLERHRRMHEVGQEKPYSCPRCLMRFETRNLYNHHAKTHKPILTGNDRITDTSMVSSGDPVTSSITGNIVAPQNKSIASYPCDSCSKQFASMESLTTHKAVHRSRSLVCDVCGKGFTHRKYYVVHQRIHTGERPYLCAMCGKSFTQASTLTVHRRYHTGERPYTCPLCGKGFVTRTIMLNHMKKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00118215;
90% Identity
iTF_00864160;
80% Identity
-