Basic Information

Gene Symbol
ZBTB41
Assembly
GCA_028453695.1
Location
CM052104.1:9485992-9487338[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0014 0.099 13.0 0.3 1 23 85 107 85 107 0.94
2 12 3.4e-07 2.4e-05 24.3 1.6 2 23 114 135 114 135 0.97
3 12 3.1e-06 0.00022 21.3 6.0 1 23 166 188 166 188 0.95
4 12 0.00013 0.0094 16.2 4.8 2 23 194 215 193 215 0.97
5 12 0.00051 0.036 14.4 0.1 1 23 220 242 220 242 0.98
6 12 6.9e-07 4.9e-05 23.4 0.7 1 23 250 272 250 272 0.98
7 12 0.047 3.3 8.2 2.0 1 23 278 301 278 301 0.94
8 12 0.00011 0.0078 16.4 0.3 3 23 314 334 312 334 0.96
9 12 6.2e-07 4.4e-05 23.5 1.8 1 23 340 362 340 362 0.96
10 12 1.6e-08 1.1e-06 28.5 0.2 1 23 368 390 368 390 0.98
11 12 1.3e-07 8.9e-06 25.7 0.9 1 23 396 418 396 418 0.98
12 12 0.00017 0.012 15.9 0.8 1 21 424 444 424 445 0.96

Sequence Information

Coding Sequence
ATGTGCCCATTCCGCTTTTTCTATTCCAGGTACAACCACCAGCTACAGTTTTCCGAAGAGTATTATCCGATGTTGACGAAGCTTGACCTGATGAAGAAGGACGCGGCCAATCCGGTTCCGAAAAGTAGCGCCCAGGTAGCGATTCCCGGGAACGTACCGGCTGCGATCGCGGCTCCGTCGGCTAGCCAGGAGCAAAGCTTCATAAAGCAGGAGGTGAACGACGAGGACGACGACGAGGACCTGCCGTTGGCTTATCACTGTAAACTGTGCGGCGTGTTCTTCGCTTCCCAGGCTCTGCTGGACAATCACGAGATCGAGCACAAGGGCAAACGCAAGAACACGTGCGCGCAGTGCGGCCGCGTGTTCCGAACGTACGTGAACCTGCGCAAGCACATGAAGAAGCACGCGGGCAGGAAAGGCGGCCGGAAGTCTGGCAACGGCTCGCTGAACCGTTCCGCCTCGCtcaaggtgaagaaggagaagccggagctcgagttcctctgtaagacctgcaacaaggtgttccggcacaagagcaactaccagaagcacctgatgcggcacactgtcggcgacctcacttgcaaacactgcccgaagaagttccgtctgttccgcgacctgaccaggcacgagaagacgcacttctaccccagctatatgtgtaaagagtgcgactacgagactaccgtgctggcagccctcagcatccacatgctgagacacaccgacaaagcggacctgccgtttcagtgcaacgactgcgacaagcggttccgcaaggcgatcgacctgcaggagcactacaatatccattccggggacaagccgttcgtctgccagctctgcggcagcgcgttctatctgaggaggcagctgtcggctcactgcaggcgcatgcatcccgagatgaaggccaacaaggtgaccagcaccgcctgcgacatctgcggccgcgtcctcgccaccaagagatccctcttccgtcacaaggagagccacaatccgaccaagctctacctctgcgactactgcggcaagagcctcagcagcgccgagcatctcaagaagcacaggcgcatacacaccggcgagaagccctacgtctgcgacatttgtggcaaggggttcaccgactcggagaacctcaggatgcacaggagggtgcacaccggcgagaagccgtacaagtgcgaccagtgtcccaaggcgttctcccagaggtccacgctgaccatccacaggagaggtcacacgggcgaaaggccctacgtctgtcagatctgcaaccgaggattctcctgtcagggcaatctgaccgctcaccaaaagtcgacctgcgtctaa
Protein Sequence
MCPFRFFYSRYNHQLQFSEEYYPMLTKLDLMKKDAANPVPKSSAQVAIPGNVPAAIAAPSASQEQSFIKQEVNDEDDDEDLPLAYHCKLCGVFFASQALLDNHEIEHKGKRKNTCAQCGRVFRTYVNLRKHMKKHAGRKGGRKSGNGSLNRSASLKVKKEKPELEFLCKTCNKVFRHKSNYQKHLMRHTVGDLTCKHCPKKFRLFRDLTRHEKTHFYPSYMCKECDYETTVLAALSIHMLRHTDKADLPFQCNDCDKRFRKAIDLQEHYNIHSGDKPFVCQLCGSAFYLRRQLSAHCRRMHPEMKANKVTSTACDICGRVLATKRSLFRHKESHNPTKLYLCDYCGKSLSSAEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRVHTGEKPYKCDQCPKAFSQRSTLTIHRRGHTGERPYVCQICNRGFSCQGNLTAHQKSTCV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00866161;
90% Identity
iTF_00862725;
80% Identity
-