Basic Information

Insect: Atrophaneura dixoni
Gene Symbol: ZEB2
Assembly: GCA_018248015.1
Location: DWHX01009762.1:3700-8607[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 3.4 5.4e+02 3.0 0.6 12 19 23 30 12 32 0.65

2 9 0.083 13 8.0 1.2 2 23 34 56 33 56 0.95

3 9 0.00035 0.055 15.5 2.9 1 23 59 82 59 82 0.97

4 9 0.0015 0.24 13.5 2.5 1 23 85 107 85 108 0.95

5 9 0.029 4.6 9.5 0.1 3 20 117 134 116 136 0.93

6 9 0.0002 0.031 16.3 0.1 2 23 149 171 148 171 0.94

7 9 1.4e-07 2.2e-05 26.2 1.1 1 23 177 200 177 200 0.98

8 9 0.00019 0.03 16.4 0.4 3 23 211 231 210 231 0.97

9 9 0.021 3.2 10.0 0.1 1 19 237 255 237 255 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	3.4	5.4e+02	3.0	0.6	12	19	23	30	12	32	0.65
2	9	0.083	13	8.0	1.2	2	23	34	56	33	56	0.95
3	9	0.00035	0.055	15.5	2.9	1	23	59	82	59	82	0.97
4	9	0.0015	0.24	13.5	2.5	1	23	85	107	85	108	0.95
5	9	0.029	4.6	9.5	0.1	3	20	117	134	116	136	0.93
6	9	0.0002	0.031	16.3	0.1	2	23	149	171	148	171	0.94
7	9	1.4e-07	2.2e-05	26.2	1.1	1	23	177	200	177	200	0.98
8	9	0.00019	0.03	16.4	0.4	3	23	211	231	210	231	0.97
9	9	0.021	3.2	10.0	0.1	1	19	237	255	237	255	0.96

Sequence Information

Coding Sequence: ATGGTGAgGATGTGGAATCTTTTATTTGTGATGATTTGCGATGAATTATGCTGTGGTAAAAATCAAAGATGGAGTCATCTGAAAAAGCATAAAGTGTtgcaatgtttaaaatgtgaaTTACTTTTCGGgagTCGTCAGGATTTCTTCAAACACTACAAACAATGGCATGAGAAGTTCATTTGTGATTATTGCGGTATCAGCTTCAAAATGAGGTACTGCATCAAGGATCATATAaaGAAGCAACATACACCATTTGAATGCAAGTCGTGTTCAAAACGTTTCGCCCGATACAACGGTCTGTGGCTTCATAACAAAATCCATCACGGAGGACCGTCCTCGCCCGCATACTGCGTGGAGTGTGACAGGAAGTATCCGGATAGCTACAGGTACAAGTGGCACTTGGCGAACAGTACGAAGCACAAGCCGCGCCAAAAATTGAGGATCCCATGTCcggaatgtaataaaatattctcaaaGAACATATATATGAAGGATCACTACAACTTGGTACACTTAAAGAATTTCAAGTATCGATGTGAGGAATGCAACAAGaacTTCATCCGGAACGCTGATCTTACTAAGCACACCCGCAGGATCCATGAAGGTATCATGCCGCCGAAAAACAAGATCTGCTACATGTGCGGTCGTGGCTTCACTACTAACAAGATCCTGGCGAATCATCTCAGGACCCACACCGGTGAGCGTCCTTTCGCCTGTGCTCATTGCAAGGCCCGATTTGCACAGTCCGCCGCACTTGCCTCCCACTGTTCTGCCATTGAACAGAGTGACGTTCCTAAGTGGTCCCGAATCGTGGGACCAGGTTACGACATTGGTGGTACGTTGCGTAGAGTCACCAAATCCGTGTGA
Protein Sequence: MVRMWNLLFVMICDELCCGKNQRWSHLKKHKVLQCLKCELLFGSRQDFFKHYKQWHEKFICDYCGISFKMRYCIKDHIKKQHTPFECKSCSKRFARYNGLWLHNKIHHGGPSSPAYCVECDRKYPDSYRYKWHLANSTKHKPRQKLRIPCPECNKIFSKNIYMKDHYNLVHLKNFKYRCEECNKNFIRNADLTKHTRRIHEGIMPPKNKICYMCGRGFTTNKILANHLRTHTGERPFACAHCKARFAQSAALASHCSAIEQSDVPKWSRIVGPGYDIGGTLRRVTKSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -