Acin050099.1
Basic Information
- Insect
- Athripsodes cinereus
- Gene Symbol
- ZFX
- Assembly
- GCA_947579605.1
- Location
- OX388305.1:39968222-39970747[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.017 1.9 10.5 3.7 2 23 13 35 12 35 0.91 2 14 0.0016 0.18 13.7 0.3 1 23 40 62 40 62 0.97 3 14 0.00016 0.017 17.0 0.9 1 23 68 90 68 90 0.98 4 14 0.0051 0.56 12.2 10.1 1 23 96 119 96 119 0.96 5 14 0.0042 0.47 12.4 2.8 2 23 126 147 125 147 0.91 6 14 1.4e-05 0.0015 20.3 1.8 1 23 153 176 153 176 0.96 7 14 0.0013 0.14 14.1 0.6 3 23 507 528 505 528 0.96 8 14 0.02 2.2 10.3 0.3 1 21 529 549 529 550 0.95 9 14 0.03 3.3 9.8 0.3 2 23 594 616 593 616 0.90 10 14 0.004 0.44 12.5 0.2 1 23 621 643 621 643 0.98 11 14 6.9e-05 0.0076 18.1 1.6 1 23 649 671 649 671 0.98 12 14 7.9e-05 0.0087 17.9 6.9 2 23 678 700 677 700 0.96 13 14 7.4e-05 0.0082 18.0 0.9 1 23 706 728 706 728 0.96 14 14 5.8e-06 0.00063 21.5 0.6 1 23 734 757 734 757 0.95
Sequence Information
- Coding Sequence
- ATGGAAGAAAATAAGCAAGCTGATGTGGCCAACTGCATTTGTCACATGTGTGGAGCTACTTTGAAGAATAAGTCAACACTGCGAGAACATTTCTTATATTCTCATCCAACACAACTGTTTATGTGTGCTCTGTGTCCCAAAATATATCGCGTCAGACGCAAGCTGGTAAAACATCTTATGATTCACAATGCGGATGAACGTTTCCAGTGTGACTATTGTCCCAAGAAATTTGCATTATTTGGAGATTGGAAGAGGCATGTGCGGTATCATAGTTTTGCTAAGAAGCATCACTGCGACTCTTGCACTAAAAGTTTCAAACATAATTGTGAACTGAGGAAACATATAAATACAGTTCATTTGAATATAAGAAATTGTATTTGCAACGTGTGCGGTGCAGGATTCGGTACAAAGACACATCTGAAACGGCATTCTTACTTACACACCGGCCTTAAACCTTACAAATGCCAGTTCTGCGGGAAGGAGTGCACTCAGTCCACCAATCTCAAGATTCATATAATGGGAGTTCACAAAGAGTTGAGTCATTTGGTTTATAAAAAGGAATTGTCTAACCCGGTTAATATAGATCCCGCCTCCGTTGTTGTTCCCTCATACGAAGATTATGTTAAAGAAACAAAACCAGTTCCTAAATCAATTAAACCAATCAAACCACCCAAAAAAAGAACTGGAACGCTGCAAAAAAATAAAGCTGGTTGTACAAAGAAAAATAAAACAGTGGGTCCAGAAAAAAATAATGTGGAAAATACAGAAATAATCAAAGCAGAGAATTCGGAGAGTATTAAAACAGAGAATGCGACAGAACCTATACCAGAAAATGTGGCAAAAAGAAAAACAAAAAGTCCAAAAAAAATTAAAAAAGCGAAACAACCGAAAGACAGAATATCCAAAATATCTAAAAATAAATATGAATCCAACAGTATAAAGCCATTAGAAAAAAATAAGAAGTCTAAGTCAAAAAAATTGAAGAAAAAAATACTCAAAGAAAATAAAAAAATGTTTAAAGATGATACCAATATAAAATATGACGGCGATGAAGATTATTATGCAGATCATTATTCTGATGATGACAGCTTCAATGTTCCTATCTTGTGGCTCCCAGAATATTCAGAGAAACCTCAAGTGGATGATATTAAAGAGGAGCCATTGTCCCCAAAAGTAGAATGTCCATCACCAGAGATGGAAGAAGGCTTCGTGAAGGATGAGTTTAGTGATGATAAGTGGAGCAAGACGGTTGGAGCTGGTAAGGATGTAAAAAAAGAAGACGATTCCTCAAAATGTTGCATCCCTAAGGCTGTCAATGATGAGATAAAGTCAACTGTATATGACAAAGACACAACTGATTACGATGATATTAAAGCGGAGGACAAGAAGGAAAATAAATTTAATTGTAAAATATCTAACATAGTGGACACCAAGACAATCAAGTCAAGTAAAGAAATCAAATCGGACGATGGTGAATCTAATACAAAGATCATTGAGAAAAGTGATTTTTGTAAACTGTGTACAGTCTGTAGTAAAGAATTCAGATCTAGAACTGGTCTGTACACTCACATGATCAACATACACCACCAGTGTACATTGTGCAGCAAAGTGCTAGACAATCCAGAAGCTGTCAAGAGACACAGGAAGAATGATTGCTGTCAGGACTGTGATGAAATGGGAATAACCAAGGACCAATGTAAAAATCATAAAGAGAGGGTCGTCCAACCGATACAGAGAGGAGATAAAACCAAAAGTAAACCACGACCCGATAAGAGCTGTTACTGCGATGTCTGTGGAATCAAGCTGAGCGATTTGCGTGCGTTAAAAGTTCATTTAGTCAACATGCACAGCACTGTCAAGTTCCAGTGTGATCAGTGCCCCAAATATTATCCCGAAGAGTGGAAGCTGGAGAGACACAAGTTGGTCCATTCTGGAGACGAACCATTCAAGTGTAAGCTGTGCCCCAAGAAGTTTGTTATATACTCCACCCTAAAAATACACATGACCTCTCACAGCAGCGCTAGAGATTGTGTATGTCACATTTGCTCGAAAAAGTTTAAAAACAAACACGGACTGCGTAAGCATATCGAGACGGTGCATATGAATGTGAGGAAGTATGTGTGTAACGTATGTGGGGCTGCGTTCAAAGGTAATTATCAATTGAAACATCATCTGTTCCTGCACACAGGAGAGAAACCATATGTCTGCCAGTTCTGTGGCAAAGAATGTACTCAAGCCAGCAATCTGAAGATACACATCATGGGGGTCCACAAGGACTTGAGTCACTTAGTTTACAAGAAGGAAGAAAATCCTTTCAAAGAGGTAGATCCTCAACTAGCCACCATGCCTAAATTCTCAAAAGATTATTTGAATACTCAAGAATCAGTCACAAAACAATCTAATATTAATAATCAAAGTATTATACCGACACAATCAATGGAACTTACAGAGAGTGGCCTTCAGACACAACCAATGGAACATGTAGAGAGTGACAAAACAGTGAGTTCTGAGTACAGTGCGAGTTAA
- Protein Sequence
- MEENKQADVANCICHMCGATLKNKSTLREHFLYSHPTQLFMCALCPKIYRVRRKLVKHLMIHNADERFQCDYCPKKFALFGDWKRHVRYHSFAKKHHCDSCTKSFKHNCELRKHINTVHLNIRNCICNVCGAGFGTKTHLKRHSYLHTGLKPYKCQFCGKECTQSTNLKIHIMGVHKELSHLVYKKELSNPVNIDPASVVVPSYEDYVKETKPVPKSIKPIKPPKKRTGTLQKNKAGCTKKNKTVGPEKNNVENTEIIKAENSESIKTENATEPIPENVAKRKTKSPKKIKKAKQPKDRISKISKNKYESNSIKPLEKNKKSKSKKLKKKILKENKKMFKDDTNIKYDGDEDYYADHYSDDDSFNVPILWLPEYSEKPQVDDIKEEPLSPKVECPSPEMEEGFVKDEFSDDKWSKTVGAGKDVKKEDDSSKCCIPKAVNDEIKSTVYDKDTTDYDDIKAEDKKENKFNCKISNIVDTKTIKSSKEIKSDDGESNTKIIEKSDFCKLCTVCSKEFRSRTGLYTHMINIHHQCTLCSKVLDNPEAVKRHRKNDCCQDCDEMGITKDQCKNHKERVVQPIQRGDKTKSKPRPDKSCYCDVCGIKLSDLRALKVHLVNMHSTVKFQCDQCPKYYPEEWKLERHKLVHSGDEPFKCKLCPKKFVIYSTLKIHMTSHSSARDCVCHICSKKFKNKHGLRKHIETVHMNVRKYVCNVCGAAFKGNYQLKHHLFLHTGEKPYVCQFCGKECTQASNLKIHIMGVHKDLSHLVYKKEENPFKEVDPQLATMPKFSKDYLNTQESVTKQSNINNQSIIPTQSMELTESGLQTQPMEHVESDKTVSSEYSAS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -