Acin039146.1
Basic Information
- Insect
- Athripsodes cinereus
- Gene Symbol
- ZEB1
- Assembly
- GCA_947579605.1
- Location
- OX388321.1:18632382-18635983[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 0.0017 0.18 13.7 3.0 1 23 43 65 43 65 0.98 2 21 3.9e-06 0.00042 22.0 0.4 1 23 71 93 71 93 0.99 3 21 2.1 2.3e+02 4.0 0.1 1 11 99 109 99 111 0.90 4 21 2 2.2e+02 4.0 1.1 1 23 217 239 217 240 0.94 5 21 0.014 1.5 10.9 0.2 1 23 276 298 276 298 0.98 6 21 0.0066 0.72 11.8 3.9 1 23 304 327 304 327 0.96 7 21 8.2e-05 0.009 17.8 0.4 1 23 378 400 378 400 0.98 8 21 8.4e-05 0.0092 17.8 0.6 1 23 406 429 406 429 0.96 9 21 0.00044 0.048 15.5 0.2 1 23 435 457 435 457 0.98 10 21 0.00023 0.025 16.5 3.2 1 23 463 485 463 485 0.93 11 21 0.0017 0.18 13.7 0.5 1 23 491 513 491 513 0.95 12 21 2.9e-05 0.0032 19.3 0.7 1 23 519 541 519 541 0.98 13 21 0.0041 0.45 12.5 2.3 1 17 547 563 547 564 0.94 14 21 0.13 15 7.7 0.9 1 23 630 653 630 653 0.91 15 21 1.4 1.6e+02 4.5 0.2 1 23 658 679 658 679 0.90 16 21 0.039 4.3 9.4 2.9 2 23 796 818 795 818 0.94 17 21 4.4e-05 0.0048 18.7 0.2 1 23 824 846 824 846 0.95 18 21 0.0005 0.055 15.4 0.9 1 23 852 875 852 875 0.96 19 21 0.0008 0.088 14.7 2.4 1 23 881 903 881 903 0.98 20 21 2.8e-06 0.00031 22.5 1.3 1 23 909 931 909 931 0.98 21 21 1.1e-05 0.0012 20.6 2.3 1 23 937 960 937 960 0.98
Sequence Information
- Coding Sequence
- ATGATAAAGTGCACAAAACTTCTACAGAATCAAATGGGTGATGTGCACATTACCAGCAATAAATCAGAAAATACTACAAATATATGTACAGATAAAACTATGGCATCTGTAGTGGGCAAAGGCAAATATTCCTGTAGTTTATGTCAAAAATCATTTAATAAAAAACGCACCATGGAACAGCATTCTCTGACGCATTTACATACACGCTCTTATGTGTGTGAGACATGTGGAAAACCATTTAAATTATTGTCTACATTGAATATTCACCTCAAGACACATACCAAAGTGTATCCACACACCTGTCAAGTGTGTGGCATGAGGTTCAACCTGACTTTACGCCAAGCCCGTGTGAAACAAAGGGTCGTATTGCACACACCATTCACAGATTCTGCAGAGAAGGGAACATATTCTGATCTGTTGATTAGTAGAACACAGACCGAGGATTTATCCTCAGAAGGTCTGAGTGAGTTGAAAAATAAATACACTCTTTTAAAAAGTATTGTGACCAAGTTACAAGCACATGTGAGTGAGTACCATAACATACAAGCATCTAGTGGGTGGGAGAGTGATGATGACTGTCAACCACTTTCTACATTAGTGAAAAGACTTGATAATGATACAACTAGTAGCAAAGCATCAGATACCAACTACCCTTGCACCAGATGTGTGTATACAGGGATGTCACAACAAATGTTGAAGGAACATACAGAACTGCATCACAATTATTTGCAAAATCTCTTTAAAAGAAGTACTAGACGAGCATATGATCCAAATACTCGACAGGAAATAGAAAAAGCAAAAATAAAAGTCAAAGAAAAAATTAGATACAAGTGTTCCATGTGTGGACTAATTGTCAACAGTGCATATAGTTATGTGTCCCATAGAACTATACATTCCAATCATAAAGTGTTCTCATGTAAGCTGTGTGGAAGGAAATTTCGATTGCTGGTATTCCTTAAAAATCACTTGAAGCACATGCATCAGATGAAATGTAAAAGTGATGCTAAGAAACTAAGTAAACTGGGAATAGAGGATGTAGATGATGAAGCGCCTGCGAATCAGCCAATGAGAAGTCATCTCAACTATAGTGACATAGAGAAAGCCAAGGTGCAGGTTGATGGACACACTTATTACAAGTGTGAGATATGTGGCAGGAAATTGTCGAGGATAAATTATTTGCTGAATCATATGAGCATCCACAGTGGAGAGAAAAAGTATGTGTGTCACCTGTGTGGGAGAGCATTCCGACTCTCCGCTATGTTAAAGGTGCACGTAAAACTTACTCATGACAAAGTGAAAAACTATGCCTGTGAGGTGTGTAACATGAAGTTTGGTACTACCACCAACCTCATAGAGCATGGCCGCACTCACACGGGGGAGCGGCCACATGTATGCATTAAGTGTGGGAAAAAATTCAAACAAAAATCTGCCTTGTTTGTGCACAATAGAACTCATACAGACCACTTCCCTTACAGTTGTATAGAGTGTGGTGCCAAATTTAGAATACAGTCGCAGCTGAAATATCACATGGCCCGACATACTGGAGACACGCCATATGTGTGTGACAAGTGCGGGCGGGGCTATGCCATCAAGAGTCATCTTAATAGACATGCCAAGGTGCACATCGAGGGCAGGCCACATCCCTGCACATACTGCTCTAAGACATTCAGACACAACAAAAACCTGAAATATTTTGTTGGAAATCCGCATAGTGTGATTGGCATCCTTTCTTCCAGATTACTGCGTGGAACATGCCCACCAGATGTGACAGAACGCTTGACTAAAGGCAAGAAACTTGCCACAGCCAGAGCGCAGCGTCAATTGCGCACAAATAGTTTAAAACAACCAAATGTAACTGAGAAGAGCCAGTCAACCGTTACCAATCCTCACATATGTTCTTTCTGTGCACAATCATTTAAAGATTCCGACATACTCACTAATCACTTGTTAGACTCGCACGCTGATTTACTGTTTCGTTGTGATGTATGCGGCTTGTATTTGGACAGGAAGGAGCTTATCCCTCACATGTCCAAGCATGCAGAGCAATACAATGAGAATTTACTGAAGCGAGAATCTACCACTAGTTGTAAGCAAACTAATATTGCACAATCAAATACCAAACTCAGTAATAATACCAATAATCAGACTGTACCACAAAATAACCTTGTCAATGAGACTGATGCCTTTTCAACTACAAGTCGGTCCAATGATGGCTTTGGACCATTACCAGAATCTGTATTTGAGGCTATTAAAGATACAGATGAAGCTGCAGAGGCCACTAAGGCTGTTGAAAAAAGTGCTGGAGAAGCACCTGAAAAAACTCAAAGCCAAATCAAATGCGAGACTGAAGATAAAATAAAGAAAAACAATGAACCTAATAAAATAGTTTGTCCAATATGTTCAAAAGAGTTTAGATTAGCATCCAGTTATCATTACCACAAGAAGCATTATCACGGGGGTGTCAAGGAGCATGTGTGTAATGTGTGTGGCAGAAGCTTCGCTGTCAAGAGTGCCTTGAAGGAACACGGTTCTATTCATTCAGGCACCAAGCCTTATTCGTGTCCACAGTGTTCCAAAGAGTTTCGAACTAAAGCCAGTGTTTACATACATTACAAAAACATCCACTGTGAAACCAAACAGTTCCAATGTACAATGTGCAACAGGTCCTTTAGGTGGAAACAGAAACTCCTTAGGCATATCTCCAGTCACACCAAGGAGAAAAAATACTTCTGCCCTAAATGTAATAAGGGCTTTGGAGTCAAGTATGATCTCACCAGACACATGAAGTCTCATGTCGAGTCTAAGGCCTACTCTTGTGACAAGTGTGAGAGACCTTTCTCACAACTCAGATATCTCAAGAAACACATCAAGACTAAACACTCCACGTCACCACCGGATATACAGCAGCAGATCAGTCTCACTTGA
- Protein Sequence
- MIKCTKLLQNQMGDVHITSNKSENTTNICTDKTMASVVGKGKYSCSLCQKSFNKKRTMEQHSLTHLHTRSYVCETCGKPFKLLSTLNIHLKTHTKVYPHTCQVCGMRFNLTLRQARVKQRVVLHTPFTDSAEKGTYSDLLISRTQTEDLSSEGLSELKNKYTLLKSIVTKLQAHVSEYHNIQASSGWESDDDCQPLSTLVKRLDNDTTSSKASDTNYPCTRCVYTGMSQQMLKEHTELHHNYLQNLFKRSTRRAYDPNTRQEIEKAKIKVKEKIRYKCSMCGLIVNSAYSYVSHRTIHSNHKVFSCKLCGRKFRLLVFLKNHLKHMHQMKCKSDAKKLSKLGIEDVDDEAPANQPMRSHLNYSDIEKAKVQVDGHTYYKCEICGRKLSRINYLLNHMSIHSGEKKYVCHLCGRAFRLSAMLKVHVKLTHDKVKNYACEVCNMKFGTTTNLIEHGRTHTGERPHVCIKCGKKFKQKSALFVHNRTHTDHFPYSCIECGAKFRIQSQLKYHMARHTGDTPYVCDKCGRGYAIKSHLNRHAKVHIEGRPHPCTYCSKTFRHNKNLKYFVGNPHSVIGILSSRLLRGTCPPDVTERLTKGKKLATARAQRQLRTNSLKQPNVTEKSQSTVTNPHICSFCAQSFKDSDILTNHLLDSHADLLFRCDVCGLYLDRKELIPHMSKHAEQYNENLLKRESTTSCKQTNIAQSNTKLSNNTNNQTVPQNNLVNETDAFSTTSRSNDGFGPLPESVFEAIKDTDEAAEATKAVEKSAGEAPEKTQSQIKCETEDKIKKNNEPNKIVCPICSKEFRLASSYHYHKKHYHGGVKEHVCNVCGRSFAVKSALKEHGSIHSGTKPYSCPQCSKEFRTKASVYIHYKNIHCETKQFQCTMCNRSFRWKQKLLRHISSHTKEKKYFCPKCNKGFGVKYDLTRHMKSHVESKAYSCDKCERPFSQLRYLKKHIKTKHSTSPPDIQQQISLT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -