Basic Information

Insect: Athrips mouffetella
Gene Symbol: ZEB2
Assembly: GCA_947532105.1
Location: OX383983.1:323349-333327[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 3.3e-06 0.00039 22.0 0.5 1 23 216 238 216 238 0.98

2 12 0.0049 0.59 12.0 1.2 1 23 244 267 244 267 0.97

3 12 2.5e-05 0.0029 19.2 1.7 1 23 273 295 273 295 0.98

4 12 2.1e-06 0.00025 22.6 1.7 1 23 300 322 300 322 0.98

5 12 4.3e-05 0.0051 18.5 2.4 1 23 328 350 328 350 0.98

6 12 7.9e-07 9.3e-05 23.9 1.1 1 23 356 379 356 379 0.95

7 12 2.2e-06 0.00027 22.5 2.8 1 23 385 407 385 407 0.97

8 12 3.3e-05 0.004 18.8 2.6 1 23 413 435 413 435 0.98

9 12 0.00043 0.052 15.3 2.4 1 23 441 463 441 463 0.99

10 12 3.8e-08 4.5e-06 28.1 0.7 1 23 469 491 469 491 0.98

11 12 4.6e-06 0.00055 21.5 2.2 1 23 497 519 497 519 0.98

12 12 0.061 7.2 8.6 4.0 1 23 525 544 525 544 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	3.3e-06	0.00039	22.0	0.5	1	23	216	238	216	238	0.98
2	12	0.0049	0.59	12.0	1.2	1	23	244	267	244	267	0.97
3	12	2.5e-05	0.0029	19.2	1.7	1	23	273	295	273	295	0.98
4	12	2.1e-06	0.00025	22.6	1.7	1	23	300	322	300	322	0.98
5	12	4.3e-05	0.0051	18.5	2.4	1	23	328	350	328	350	0.98
6	12	7.9e-07	9.3e-05	23.9	1.1	1	23	356	379	356	379	0.95
7	12	2.2e-06	0.00027	22.5	2.8	1	23	385	407	385	407	0.97
8	12	3.3e-05	0.004	18.8	2.6	1	23	413	435	413	435	0.98
9	12	0.00043	0.052	15.3	2.4	1	23	441	463	441	463	0.99
10	12	3.8e-08	4.5e-06	28.1	0.7	1	23	469	491	469	491	0.98
11	12	4.6e-06	0.00055	21.5	2.2	1	23	497	519	497	519	0.98
12	12	0.061	7.2	8.6	4.0	1	23	525	544	525	544	0.96

Sequence Information

Coding Sequence: ATGTCTGAAACGTGGAACACTGTTGGTTTGTGCCGTTGTTGTCACGCTGAAGGCAACGTGAGGAGTTTGGGGGCCTCTTATTGTGAACAAAACATCGACGAGATTTACTCCGTTATGTTGAGGGAAGCTTTTGATATTATTATCAGTCCAGTGGTGTCTATGGAAATGGACAGCGCTTCTTCATATTGCATTTGTTCAACGTGTGTCCCTCGGCTGAGAGATGCTCTTCACTTCAAGAGGCAAGTTCTTCGGTGCGAGGAGAAATTTGCACACTTTTGTGTTAAGGCTCTGAAAGATGAACATATCAATACAGATGACGTTGCTAATGAGACTTACGATGATGGTAAGTGGAACTTGCGTATCGTACCACCTTACATACTGCGGTCACCAACAACCGCGGTCCATAGTGCTAGCCGCAACGCTAACAAGCGTGGTGACTATGATATATTTTCTCTCGGGCAGCGTGCTAAGCCGGGATTCATTTCAGTTTCAAGGTCATGCGAGGACACCGGCCCCGCGTCCGACGCAGAGGGAGATGACGAGCCACTGTCGCTGCTGGCTGCTAGCAAGGCGAGGGATGATGATGAGGATGGATTCTTACATACTGTTAAAGATGAACCATCAAAATGTGAGCTAAGGAAAAAATACTCATGCAGTCTCtgcgagaaacagttttcatacaacggttcattagaagtgcacatgaaaattcataccggagagaaaATCCATCGTTGTCTACTCTGCGATGCTCGATATCCACTCAACCGGGACTTAACCAAACATATCAGTACAACGCACAGACAAAATGGCCAGTACCCATGCAATATATGCCATCTGGTCTACGATAAAGCATCAAAACtaaaaactcatttaaaaacccattacgaacaaaaattcaaatgcaactcatgtggaaaggattttcgaagaaaaaaaggtttaacggaacatctcaaagtgcattccggagagaagaaatattcatgcagtatctgtttgaaatcttttgggcataatcaaacgttgaagtcacatattctgacccacaccggggaaaagccatacgtttgtgatgtatgcggaaggaggtttcctcaacgaacacatttaaaaagacatatttttataatacatgcgggtatgaaacctcattcgtgtaatatctgcaataaacagttttcaagtaaaagttacttaactatacatgagagagtgcacagcggggagaaaccattttcatgtgacgtttgcaagaagaatttcactgctcatacaactttaaaagtccatatgaggatccataccggattgaaaccgtacacatgcaacttttgttcgagaaagtttgcccaaatggcaagtttcaaactccacgaacgaacccataccggagcgaagccatattcctgtgaaatttgcaacaaaagattttcagacaatggttatttgaaaattcacatgcgaatacatacaaatgagaagccgttcgaatgtgaggtctgcaaaagatcttttagggagaccggtcagctgaaacggcataaaagaacacattcaggggtgaaaccgtatacatgtaaaatatgtaacaaacaaattgggaacttgtcgaagcatatgcggacgcatgcGGACATGCGGGGTACATGCGACCGCATGCAGATGACATGA
Protein Sequence: MSETWNTVGLCRCCHAEGNVRSLGASYCEQNIDEIYSVMLREAFDIIISPVVSMEMDSASSYCICSTCVPRLRDALHFKRQVLRCEEKFAHFCVKALKDEHINTDDVANETYDDGKWNLRIVPPYILRSPTTAVHSASRNANKRGDYDIFSLGQRAKPGFISVSRSCEDTGPASDAEGDDEPLSLLAASKARDDDEDGFLHTVKDEPSKCELRKKYSCSLCEKQFSYNGSLEVHMKIHTGEKIHRCLLCDARYPLNRDLTKHISTTHRQNGQYPCNICHLVYDKASKLKTHLKTHYEQKFKCNSCGKDFRRKKGLTEHLKVHSGEKKYSCSICLKSFGHNQTLKSHILTHTGEKPYVCDVCGRRFPQRTHLKRHIFIIHAGMKPHSCNICNKQFSSKSYLTIHERVHSGEKPFSCDVCKKNFTAHTTLKVHMRIHTGLKPYTCNFCSRKFAQMASFKLHERTHTGAKPYSCEICNKRFSDNGYLKIHMRIHTNEKPFECEVCKRSFRETGQLKRHKRTHSGVKPYTCKICNKQIGNLSKHMRTHADMRGTCDRMQMT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -