Basic Information

Gene Symbol
Sall1
Assembly
GCA_033675125.1
Location
CM066218.1:2945726-2955807[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 2.9 3e+02 3.3 0.3 2 23 7 28 6 28 0.96
2 14 0.095 9.9 8.0 0.6 1 23 999 1022 999 1022 0.91
3 14 9.4 9.8e+02 1.7 0.2 1 23 1101 1123 1101 1123 0.84
4 14 3.4e-05 0.0035 18.8 2.5 2 23 1126 1147 1125 1147 0.97
5 14 0.013 1.3 10.7 2.1 1 23 1153 1175 1153 1175 0.98
6 14 0.009 0.93 11.2 2.5 2 23 1182 1203 1181 1204 0.95
7 14 0.051 5.3 8.8 1.5 5 23 1217 1235 1216 1235 0.96
8 14 0.056 5.8 8.7 2.6 3 23 1242 1263 1241 1264 0.96
9 14 0.0013 0.13 13.9 0.2 2 23 1280 1300 1279 1300 0.98
10 14 0.00055 0.057 15.0 0.8 1 20 1306 1325 1306 1328 0.90
11 14 0.00035 0.037 15.6 0.4 1 23 1336 1358 1336 1358 0.99
12 14 0.0063 0.66 11.7 7.2 1 23 1364 1386 1364 1386 0.98
13 14 5.5e-06 0.00057 21.3 1.4 1 23 1392 1416 1392 1416 0.98
14 14 0.0012 0.13 13.9 4.2 1 23 1422 1444 1422 1445 0.95

Sequence Information

Coding Sequence
ATGGACCAGCTCGCGGTGCAGTGCCCTGTGTGCACGCTGTTCCTGCACAATGGGATCACCCTGGAGTCCCACTTGGACACACATCCCAAAGACCAGGTCATAAAAGCTTTGTGTAATATAGCAAACAAGGGCTCTAATTATGGTAGCAGGACTTCCACACCAGTACATTCTGAGCGCTCATACAGGAGCAGGTCTCGAACACCTGCCACTGATGACAGTGCCAAGTGGACTGGGTCACGTAGTAATGAACATGAGCGCTACTGGCGTAGAACACCGAGCAGGACCTCTAAATCTACACCAGTATCTAATACATCTCGGAATGGCACACCTGATATTAGAATGCTTGATGTTAACTATGACAACCATGGCATTTCTGCTGGTGGTAGTGCGGGACAACATGTTAGTAATCCATTTCATTTAAAAGCTGATAAACTTCAGCCGACCTTCCAGTGTCCCCCAGTACCAGAGTTTGATCCACAGTATGTTTACTATCCAGAGCAACAAGAGGACAGAGAGATTAAGTATTCCAGGAGTGCCGAGTACAATTccatagacaatagcagcaatATGTTTTCTTACAATGTGCCATCTATGGCAGGGCCAGGTGTGAAATTGTTACCAGCGGTGCCTAGAAAAGCAAATGACCTTGTTAAAGTTCTACCAAAACCAAATAACATACTCCTTAAGACCAATATGGGTGGTGTGCAATATATAGGCCCGGGGGTCAAGCCCATGCATGTCATGGTGCCATCTGCACCTACATTCATGCAGAAGAATATGCAAAACAATATGATCATGACTAGCAGTGTACCTAATCCACAGATGCATGTTGATGACAAAACTTCTACACCCCCTGTAGCTAGCAACCAACTGAACCAAATTACTTCTGGTGCATTCACTCCAGGAACAACTGTTGTTACCCAAAACTCCCAAATCATTTACAGAGAAATGGTGCACAACATAGATGGTAAGCCCTTCATAACTACCATGCCTACAGTTCTTGGTGGCCATGACAATGTCTCTAGTTTAGCTGCTAGCTCCATGTATCAAAATGTTATGGTTGTAGATCAGTTTGGAAACACTTCATGTATGTATACAACACCTCAACAAATGATGAATAAAGCATGTCCCACTTCCATTTATAATGATTCAGGGGCTCATTTGCCTAGTGCACACATTGATAAATCTATACAAAATATGAGTGACCCTAAAACACTTATTATTGAGGTTGGACCACTCATGGCTCCTGCTCCGGAAAATATATGTGAAGATCCAAGTTCTAGCATGCCACAGACAGTTACAAGCAGTGCTTCTAACAACACTGAGATACCAATTGAGACAGTAGACCCCAAATATGAAATGTCAAGCAGTACTAAAGGTTTGAAAATTCTAAGCAACATCAAGGTTGAAGTGCCAGTTCAACATCACAAGAACATGGTCAACACTGTCATGGATCTAACTGGCAGCAATGAAACTGAGTACCCTGTAGAACGAGCAGAGAGTCCCGAAAAGATCCTTCCAGACATAGAAGACAACAACCATCTATCATCTGATGATACGCAGCCATCCTCAATGTCCAGTGCCGACAGCATGGTCTCCCATACATTTTCTGTGATAAAGAATGTTGGTAATCCAAGCAAGAGTTCTGTAGACAATAAGTTGGACACAGACTTTTCAGACAGCTGTCCTGTGCCAGATTTAATATGTAATGAGAAGCCTTCCATATCACCTTGTAGTGAGTTGTCAGAAAATGGCGACAATTCAACCGATCGTACCTCAATGTCTCCCAAACCTGAGAGTAATCAAGTTAGCCATAGTCACTTAGGACTTCCAGAAAAGAAAATTCAGCTTTCACAGAAGCCATACAGGCACAACACTCTAAGACTGAACAATATTTTTGTGAAGAAGCACAAGAAAGTGTTGCAGATCAAGAATGCCAAGGGGTTTCCCCTGAGCACCACGAAGAAAACTGAACAGAGAGACAACATGCCGACGTCATCTACATGTCGATCACCCGAAAATTTTACCATGAATAAAATACACCAAACTGAGAAGTCAGAATTTAAGGAAAAGACTAATCTCTTACAAACAATCTCTGTGGAAGAGATCAAGGAAAATGATGAAAATAATGACTTTGATGCTGACACAGAAGAACAATCCATGGACATAGAACCACTTCCATCTGCTAGTCTGAATCAGCCTGAGTACTCAGCCAATATTGACATGGTACAGGTGAAGGAGGAAATAAACACTAGCAATGAAGGAGGATTCAGTAACGAGCCACTGACGACGAACCGCATGCTGACGCCACTCGAGACATTGAGGCCTATTAATGTTATTAGCTATGGTAATCTGTCCAATGAGGATTTTAACGAGGAATCCACAGATAGGGAGTTACTAGACCTTGAAGCAGCTTCTAAAAACAAACAGTTTGTCAGCATGATGAACGAAAATTATTTCGGCGACAATATTTATGCAGATTACTTTACTCCTGACCGCGTGGAAGCGTTTGACGCCGAGCGCGAGGCGGCGGGGTTCAAGGAGGGAGCAAAAGATGGTATGTACCTGTGGGGCGAGCCTTCTCAGAAAGACAGCGACTTTGTACTGCCTAACTTTATACACGAGAGTTACAAAATAGCTGAAAGTAATGGAATAGATTATTCTGAGTTGGGTGCTCGTGAGGTGCAGGTAGATGTGGAGGTTGACGGGTGCGAGCGCGACAGCAAGGCGGACGTGCTGAGCGAGGGCCGCAGCGAGGGCGACGCGCCGCTCAACATCTGCGCCGACGAGCGCATGCCGCCGCGCGGCGAGCTCAGCGGCCAGGAGAGCAACGGAGACATGGAGTCGCCCTGGACCGGGATGTACACGGAGGTGACCCCCGCGGAGCCCTACGACCTGATCGCCCGCGAGAGCTGGGTGTCGGACGGGTCCGAGGTGGACGCCAATGAGAAGCGGGAGCCCATCGAGGAGGAGCCGCTGTTCCGCGCGGCGCGGCACTCGTGCGGCTCGTGCGGCGCGTCGTGCGCGTCGCTGAAGGAGCTGCGCGCGCACAAGGCGCTGGCGCACGCGCTGCCCACGTGCTCCGTCACCAAGACCACGTACAGCCGCCTCGTCACCGCGCGCACCATCAAGAAGGAGGAGAAACCTGATACAAAAAACCTATTACCACCAATAGACTCAAAGGATTCGATATCGTCTACGATCCTTCAAGTGTACGAGAGCATCCAAGTTGAGGAGGCCAAGCCTAAGATAGAGGTGGACCGGCTGATCAAGCAGGAGGTGAAGCGCCGACGGAAGGACTACGTGTGCCCCACGTGTAAGGAGGACCAGGGCAACGACGCCGCCTTCCACGCGCATCTCAAGATCCATCCGCTAGAGTGCCTCACGTGCGGGAAATGCTTCTTCAGAAGAGCCAACCTGTCACTGCATATAAAGACACATTTAGGAATTAAGAATTATAAATGCGAGGTGTGCGAGAAGCGGTTCCTGACGCGCCAGAAGCTGGCGGAGCACCACAACGTGCACACGGGCCGCGCGCCCGTCAAGTGTACTGTCTGCGACGACACCTTCCGCCGGTACTCCAACATGGTGCAGCACAGGGACCGCCACCACCTGGCGAAGCGCGCCAAGGTGCGCGACTTCGTGTGCCAGTGCGGGCTGGTGTTCCACTCGCGCGCCAAGCTGCGCTGGCACCAGGAGACGCACGcggagcggccgcgcgcctgcCTGTACTGCAGCGACAAGTTCGTGCACGCCGCCTCGCTCACGCGCCACGTGCGCCGCTCGCACCACGAGTACTTCCTGGCGCAGCGCCCGCCCGGCGAGCAGCACAACGTGCAGTGTCCCGTCTGCAAGCAGGTGTACCTGCGCTCGAACCTGCGCGCGCACCTGCAGACGCACTCGGGACAGCGGCCCTACGTGTGCATCATCTGCAACAAGTCCTTCACCACGAAGTGGAACCTCAAGCTGCACCGCTGGACGCACGCCTCGCGCTCCGCCAAGCCCTACAAGTGCGGCCTCTGCAAGGGCGCCTTCATACGACAGTCTGAGTACGTGTCGCACATGAACTCTCACAAGTCGGTGCGGCCGTACACGTGCAACTACTGCGGCTGCCAGTTCATCCGCAAGTACAACTGCCAGCGCCACGTGCGCGAGCACGAGATGGCCAAGAAGTACGTGTGCAAGGTGGCCGACTGCGGCAAGTCCTTCCACCGCAGCTACTACCTCTCCGAGCACATGAAGGTGCACAGCGGCGCGCGGCCCTTCGCCTGCAACATCTGCGGCAAGACGTCCAGCAACAAGTCCAACCACAACAAGCACGTCAAGATACACCACGCGCGCGAACCCGTCGCCACCGAGGCCTAG
Protein Sequence
MDQLAVQCPVCTLFLHNGITLESHLDTHPKDQVIKALCNIANKGSNYGSRTSTPVHSERSYRSRSRTPATDDSAKWTGSRSNEHERYWRRTPSRTSKSTPVSNTSRNGTPDIRMLDVNYDNHGISAGGSAGQHVSNPFHLKADKLQPTFQCPPVPEFDPQYVYYPEQQEDREIKYSRSAEYNSIDNSSNMFSYNVPSMAGPGVKLLPAVPRKANDLVKVLPKPNNILLKTNMGGVQYIGPGVKPMHVMVPSAPTFMQKNMQNNMIMTSSVPNPQMHVDDKTSTPPVASNQLNQITSGAFTPGTTVVTQNSQIIYREMVHNIDGKPFITTMPTVLGGHDNVSSLAASSMYQNVMVVDQFGNTSCMYTTPQQMMNKACPTSIYNDSGAHLPSAHIDKSIQNMSDPKTLIIEVGPLMAPAPENICEDPSSSMPQTVTSSASNNTEIPIETVDPKYEMSSSTKGLKILSNIKVEVPVQHHKNMVNTVMDLTGSNETEYPVERAESPEKILPDIEDNNHLSSDDTQPSSMSSADSMVSHTFSVIKNVGNPSKSSVDNKLDTDFSDSCPVPDLICNEKPSISPCSELSENGDNSTDRTSMSPKPESNQVSHSHLGLPEKKIQLSQKPYRHNTLRLNNIFVKKHKKVLQIKNAKGFPLSTTKKTEQRDNMPTSSTCRSPENFTMNKIHQTEKSEFKEKTNLLQTISVEEIKENDENNDFDADTEEQSMDIEPLPSASLNQPEYSANIDMVQVKEEINTSNEGGFSNEPLTTNRMLTPLETLRPINVISYGNLSNEDFNEESTDRELLDLEAASKNKQFVSMMNENYFGDNIYADYFTPDRVEAFDAEREAAGFKEGAKDGMYLWGEPSQKDSDFVLPNFIHESYKIAESNGIDYSELGAREVQVDVEVDGCERDSKADVLSEGRSEGDAPLNICADERMPPRGELSGQESNGDMESPWTGMYTEVTPAEPYDLIARESWVSDGSEVDANEKREPIEEEPLFRAARHSCGSCGASCASLKELRAHKALAHALPTCSVTKTTYSRLVTARTIKKEEKPDTKNLLPPIDSKDSISSTILQVYESIQVEEAKPKIEVDRLIKQEVKRRRKDYVCPTCKEDQGNDAAFHAHLKIHPLECLTCGKCFFRRANLSLHIKTHLGIKNYKCEVCEKRFLTRQKLAEHHNVHTGRAPVKCTVCDDTFRRYSNMVQHRDRHHLAKRAKVRDFVCQCGLVFHSRAKLRWHQETHAERPRACLYCSDKFVHAASLTRHVRRSHHEYFLAQRPPGEQHNVQCPVCKQVYLRSNLRAHLQTHSGQRPYVCIICNKSFTTKWNLKLHRWTHASRSAKPYKCGLCKGAFIRQSEYVSHMNSHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKYVCKVADCGKSFHRSYYLSEHMKVHSGARPFACNICGKTSSNKSNHNKHVKIHHAREPVATEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00908225;
90% Identity
iTF_01026666;
80% Identity
-