Basic Information

Insect
Atherix ibis
Gene Symbol
PEG3
Assembly
GCA_958298945.2
Location
OY282610.1:14186675-14190657[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00017 0.021 15.9 1.1 1 23 159 181 159 181 0.97
2 15 0.0041 0.53 11.5 0.7 1 23 187 209 187 209 0.92
3 15 6.8e-05 0.0086 17.1 0.2 1 23 301 323 301 323 0.98
4 15 0.11 14 7.0 0.7 1 23 329 351 329 352 0.95
5 15 5.6e-05 0.0071 17.4 4.2 1 23 380 403 380 403 0.97
6 15 0.0041 0.52 11.5 0.2 1 23 418 440 418 440 0.94
7 15 2.2 2.8e+02 2.9 0.1 2 10 447 455 446 458 0.94
8 15 0.0037 0.47 11.6 0.9 2 19 477 494 477 495 0.95
9 15 8e-05 0.01 16.9 7.0 1 23 504 526 504 526 0.97
10 15 0.032 4 8.7 0.5 3 23 533 553 531 553 0.96
11 15 5.1e-06 0.00065 20.6 0.4 1 23 561 583 561 583 0.98
12 15 0.0034 0.44 11.7 0.2 3 23 591 611 589 611 0.97
13 15 0.0001 0.013 16.5 0.6 3 23 619 639 617 640 0.95
14 15 0.00048 0.061 14.4 0.2 1 23 654 676 654 676 0.96
15 15 0.001 0.13 13.4 0.2 1 20 1092 1111 1092 1114 0.93

Sequence Information

Coding Sequence
ATGGAAAATCAACCATACCAAATTGAATGGGTCGAAACAATTGATGAAGAGGGCGAAGTACTTGTAGAAGAAGTTGACGACATGGAAGGCAATAGTCAAGTTGATCGAGAGGAGTATTTAATAGGACAGGAGATCATTTCTGTAGAGGAGATAAATGGGATTCCAACAAGTTTGGATCAAATAGCTgcggaaaatttaatatacatgGCTCATGATGGACAGGTAACGGCAATGAGTGATTTGATCGAGGATACTGTTGAACGTGTTGAGAATACTGACTACAATGAACATCAATATTTTGAATGCCAGGTTACGGAAGAAGTTATTACTGATGATTGGGTACAACAACAAGGCGAAGAAAGagTGGAAATTCCTGTTGATCAGTTATGTGGATCTGGTGGGGATGCACAAATAATGGAGGAAATCGATGTTCCAATACCAACGGATCAGGATGAATATTCAGCATTAAGACCATATCCGTGTGACTTTTGCAGTCGCagatttcgtaaaaaaattagtttgacTAATCATATAAGTGCTCATCGAAATGATCGTCCACATATTTGCGATATATGCGGTgcgaaatattttcgaaaatctgAATTATTGTTACATTTTGAAGAGCATACAAAAAACCTACTACATAATGTTCCTGATATTGAACacaattttgcaaCTGATCATATCGGTGCGAAATTGCAATATAAAACCGAGCATTATGACAATGATAATATTGATCAAATTATAGATGTAAAACCAAAAGTAAATTACGGACGTTCCGGACGAGTTGTAAAACCAAAACAAGAAGTTTATTCACAGTCAGATCATAGCGTAGAATCAACAACACCAAATCCAGAGCGGTCTTATAACCGTTATTCTATAACTGATCCTAAAAAGCCATTTGTGTGCCAACAATGTGGAATTAGTTTTGCTAGAGAGAAAGCTCTTTTATCTCATTCGAGGATACATGAAGGCGATTCTACTTATGAATGCGTTACCTGCAACGAAATGTTTTGGGATATAAATGTACTAACCGATCATCAGAAAACACATCATTTTGAAGCTAGTAATTCAGAATATGAGCCAGGAAATGACGAGGAAAGTGATTCTGATCTTGACGATTCTAAATTTGGAGAATATTATTGCAGAATTTGCGGGATGAGCTTTCATAGGCAAAATTTACTTAAACGGCATACAAAGAAGGAACACGGTTCTTCTGTTAAAGATTATGGAACCGTTGGTGAAATAAGACATTGCTGTAATGTTTGCGGTGAAACTTTTGCAGAAGCTCTTGATTTGTTAGCGCATGCGGAAATTCATGCTCGTTTCCAACCAATAAAGTGTACACTGTGCGGAGAAACCTTTCTCGAAgaagcaattattaaaaaacatgtTGCTACTATACATGCGAATAATATGACATCTAATTCATGTAAAGTGTGTGGAAAGCAATGCCGGGATGCGCGTTCCCTTATGAAACACGCATGGGATCATTCGAGAGAAAGGAATCATTCATGTTCAAAATGTGGAAAGACTTTCCATAACAAAACACGtttGAGGCGGCATATGATATCGCATCGAAATAAGTCTGTTATATGCGATGTTTGTAAAATGGAGTTTCCAGATGGACGATCGCTTATGAATCATCGTCATTCACATACAAACATTTCCGGAAAATTGTTTCCATGTAGTGAGTGTGGTAAAACATTTGGCTCAAGAAGTTCTCAGCAAATTCATTTACGTATCCATACTGGTGAAAGGCCATACGGATGTCGTTTTTGCTGGAAAGCATTCGCGGATGGTGGGACTTTGCGTAAACATGAACGAATTCACACAGGTGAAAAACCTTATGGTTGTTCAGTGTGCCCTCGGGCTTTTAACCAAAGAGTTGTCCTCCGGGAACACATACGGACACATCATTCAACACCGGATCCAAAACTAGGGACAAGTCAAACTCCTTACTTCTGTACCGTTTGTTATAAAATGTTCCCTCTATCATCTGAACTTATACAACATTTAATTGAACACAGTGATACAAATACAGCCTTACAACGGCAGCCAGTTGCCGGTCCACGGAAATATAAGAGACGAAGGAAACTGAAACCCCATGAGTTGGAAAGAATACGGAATACAAAGCTTGGTCCAACTGATGCAGAAGAAGATTCCGATGAGGTGATAGTTGCTCCATTGCCAAGACGGAGTAAAACTGATCGCCCATCATATTCATCAACTGAAGCAGGTCGCAACCGTAAATATTCAGCAGGGTCTGATAAATTAAATTCTTGGCCGTCAAAATTGATGTCACCATCAGCAAATGACGACTCCTATAATTCAGTCTTTAATTCAGTTAATATTGAGAATACTTTGCAAAACATTGATTCGTTAGTTGTTAATTGTAATTCCGCACCTTCTACAAATAATGCAATAATACGCAATAAAAATTCACCAAGACGACGGACCACAAAACAATCAGATGTTAACTCGGAAAAAACAAGTCGACCAAAAATGATTCATACACAAAAAACGCGTGTAGCTGTCGAAGACGGTAAACGAAAAACTAAAACAATGATAACGCGAACAGAACCAGCCGAAATAAACGATCAAGTATTTCAACAGTTTGATGGAACAAAACCATATGAGAAAAGTAATTGCGATTATGGAAAATTAACGGTTTTGAATACCTTTtctgaatttcaaaataatcctGTAATAGTGAAAACCGAGCCGACTAGCCAAAGCGATTTGTTGGCTGCGCAATTGCTGCTGGATGCTGCATCTATGCCTAAGGAATTCAATATTCTTAACCCAGATTATGCTGTGGATATGAAtggctttttttctttaccAAATGAAATTAAAGAATCCACATCACCGCAACCGAAATCCACATCACCGCAACCCAAATCCACATCACCGCAATCGAAATCCACACCACATCAATCTCAGCAATATATTCCAATGTCGTTGCAGGCGgaagaaaaagaatttaaagaGGAAATAAAAGATAACGCTATTGAAGAACTTCGGCGATCAACACGGAGTAAACGATcaataaaatcaagaaaatacaTCGACTTTGAAGTATCACTGAAATCTCAAAAATCTTCATCGTCTGTAGCCATACATGCACCAAAAGCAAAAGATGTGTCATCAAAAATTGTTACTgtgaaacaagaaaaaattgagGAAAACCCATCTAAAGAATATGCAACCCCAATTATAACATCAACATCCACTCAGTCGGTAAAAATGGCTTCCAAGGTGAAAGGCTCTTTTCAATGTGATATGTGTTTTGCTGTTTTCTCTAATCGGTCTCAGTTACTGTTACATGTTCCAATCCATATTTAA
Protein Sequence
MENQPYQIEWVETIDEEGEVLVEEVDDMEGNSQVDREEYLIGQEIISVEEINGIPTSLDQIAAENLIYMAHDGQVTAMSDLIEDTVERVENTDYNEHQYFECQVTEEVITDDWVQQQGEERVEIPVDQLCGSGGDAQIMEEIDVPIPTDQDEYSALRPYPCDFCSRRFRKKISLTNHISAHRNDRPHICDICGAKYFRKSELLLHFEEHTKNLLHNVPDIEHNFATDHIGAKLQYKTEHYDNDNIDQIIDVKPKVNYGRSGRVVKPKQEVYSQSDHSVESTTPNPERSYNRYSITDPKKPFVCQQCGISFAREKALLSHSRIHEGDSTYECVTCNEMFWDINVLTDHQKTHHFEASNSEYEPGNDEESDSDLDDSKFGEYYCRICGMSFHRQNLLKRHTKKEHGSSVKDYGTVGEIRHCCNVCGETFAEALDLLAHAEIHARFQPIKCTLCGETFLEEAIIKKHVATIHANNMTSNSCKVCGKQCRDARSLMKHAWDHSRERNHSCSKCGKTFHNKTRLRRHMISHRNKSVICDVCKMEFPDGRSLMNHRHSHTNISGKLFPCSECGKTFGSRSSQQIHLRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYGCSVCPRAFNQRVVLREHIRTHHSTPDPKLGTSQTPYFCTVCYKMFPLSSELIQHLIEHSDTNTALQRQPVAGPRKYKRRRKLKPHELERIRNTKLGPTDAEEDSDEVIVAPLPRRSKTDRPSYSSTEAGRNRKYSAGSDKLNSWPSKLMSPSANDDSYNSVFNSVNIENTLQNIDSLVVNCNSAPSTNNAIIRNKNSPRRRTTKQSDVNSEKTSRPKMIHTQKTRVAVEDGKRKTKTMITRTEPAEINDQVFQQFDGTKPYEKSNCDYGKLTVLNTFSEFQNNPVIVKTEPTSQSDLLAAQLLLDAASMPKEFNILNPDYAVDMNGFFSLPNEIKESTSPQPKSTSPQPKSTSPQSKSTPHQSQQYIPMSLQAEEKEFKEEIKDNAIEELRRSTRSKRSIKSRKYIDFEVSLKSQKSSSSVAIHAPKAKDVSSKIVTVKQEKIEENPSKEYATPIITSTSTQSVKMASKVKGSFQCDMCFAVFSNRSQLLLHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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