Acen004057.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Atethmia centrago
Gene Symbol
L
Assembly
GCA_905333075.2
Location
HG995367.1:18553886-18574498[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.9e-06 0.00029 22.9 1.7 1 23 90 112 90 112 0.99
2 16 0.81 1.3e+02 5.2 5.8 1 23 118 140 118 140 0.97
3 16 1.1e-05 0.0017 20.5 4.1 1 23 146 168 146 168 0.99
4 16 3.4e-05 0.0052 18.9 0.1 1 23 174 196 174 196 0.98
5 16 0.0016 0.24 13.7 0.0 2 23 212 234 211 234 0.94
6 16 5.8 8.9e+02 2.5 0.1 9 23 265 280 261 280 0.93
7 16 0.39 60 6.2 0.0 3 23 332 352 331 352 0.97
8 16 0.21 33 7.0 0.0 3 23 366 386 365 386 0.91
9 16 0.00071 0.11 14.8 0.3 1 23 394 417 394 417 0.95
10 16 0.13 20 7.7 0.0 1 23 422 445 422 445 0.92
11 16 0.018 2.7 10.4 0.1 1 23 506 530 506 531 0.94
12 16 0.00026 0.04 16.2 0.1 2 23 594 615 593 615 0.96
13 16 0.075 12 8.4 0.0 1 23 623 645 623 645 0.97
14 16 1.1 1.7e+02 4.7 0.3 1 23 749 771 749 771 0.94
15 16 0.0045 0.69 12.3 0.1 1 20 779 798 779 801 0.95
16 16 0.2 30 7.1 0.3 1 23 808 830 808 830 0.94

Sequence Information

Coding Sequence
ATGGGCAATTTAGGGTGTTGTATGACATCATTCTGGGGTCCAATGGGACTCAATACCGAGCCGGTGGAGGTTCGTGTGTGCGGGTCCAAACAGGGCGCTTCCAAACTATACGAGGCGCTGGGCAGCGTGGGCAGCACGGCGGGCAGCTCTTGGCCATCGTCGACGCCGGAGCCGTCGCCGTCACCGGCGTCCACGCCCACCTCGGCCGACGCCGCCGACGCCGAGGCCGAACCGCCCTTCACGCTCGGCGCCACCGAGCACACCCCTTACCAGTGCCAGTTCTGCGATAAAGCCTTCCCCAGGCTATCTTATCTCAAGAAACATGAACAGACCCATTCGGATCAGATGCCGTTCAGGTGTGAATTCTGCTCGCGCCTGTTCAAGCACAAGCGGTCACGCGACCGCCACGTCAAGCTGCACACCGGAGACCGCAAGTACCGCTGCGCACATTGTGAATCTGCCTTCTCCAGGAGTGACCACTTGAAGATCCATATGAAGACGCACGACAATCAGAAGCCGTTCCAGTGTACCGTCTGCAACCGAGGGTACAATACTGCAGCCGCTCTGACGTCACACATGCAGGGACACAAGAGAGACCGTGAGGGTCGCGAGCCTGATAGACGCAGGGCACTGCGTTGTCTGCGATGTGGAGACGCCTTTCGACGACCAGACCTGTTGCAGgctCACATGGTGAGCGCACACGGCGTCGACACAGCAGCTATGACTCCACCGCGACGCGTCGCTTCTCAGCCGCCGCCCACACTACTCGCCTGCATCTACTGCACTCGCGACACCTTCACCAACATGGAACAGTTACAACTACACGTGCGAGCAGCACACTCAGCGCTGCTAAACGGCGAAGGGCCAGTTCAAGTTGATCAGCCTTTGCCGACTGATTTAAGCCGACGGGCACCTGACGAAGTGCCCCCAGTTAAACGTCCTCGCTCCGGATCTGGCACGCCACAAACAACTTTATCACCAAGCACACTTCTCTGCAATCAATGTGATGCTGCGCTCCCAGATTTTGAAGCATTTCGGGCTCATTTGAAAGGGCATATTGAAGAAGGAGGAGAGCTACGATCAAGTCCTGCGCCTTGCGTTCACTGTGGAGCTACGTTTGCGGATGCTGCGGCGTCTGAGCGTCACCTCACGGCACATTACTTGGCAGTCTCGTGCGAGTACACCTGCCACAGTTGCGCTCGAAGCTTCGCTGCTCCTGATGACTTGCAGAAACATCTGCTTGAACTGCACGCGCATCACTTGTATAGATGCGCTCTTTGTAAGGAGATTTTTGATTCAAAAGTTGCAATTCAGGTTCACTTCGCGGTAGCTCATAGTGGTGAAAACAAAGTGTGGGTGTGTCGTTCTTGCGGAGCGGGCGCGGGCGCTCTTCGCTCGGAGGCCGAAGGGGCCGCTCACGTGCGCTCCCGGCATGCGGCCGCAGCCCCACGGTGTGCTTGCGGAGCCCTACTTGGCAGTGGGGTTGCTGCAAGGACCCCTCGACCCCATCGCGCATATCGGTGTCCCGTACCTGCCTGCAATGATGCATTTGCTGTACAGTACTTGCTCGAAAGACACATGCAGGCTCATCATGCAATGCAACAGCAGGTTCTAAACGGAGAATTACCAAGAATAAAACGAATGGATTCCAGCAACGGGGGTGAGGGTGGTGATGACGCACGATCTCCATGTACCCCTGGAGCAGACAGCGCGGGGGTGACCTCGGCGGCGGTAGCCGCCAGCGACGAGCGGAGGCGGAAGAACGGCGCCGTAGCCTTGCAGTGTGCTTACTGTGGGGAGCGGACGCGGAGTCGGGCAGAACTAGAGGCTCACACTCGAGCCCATTCCGGGGCCGCGGCTGCTAGACACAAGTGTCTGATCTGTGATGAGGTGCTGCCGTCTGCTGCAGTGTTGGCGGAGCATAAGCTCACACATTGCAAGGTGATATCAGGCGACACGTGCTCTCGCTGCCGCGCTCGCCTGTTGTCGGAGGAGTCGTTCCTGGCGCACATGGCGCGCCACCAGCCCGCGCTGCCCGCGCCCTGCGTCGTGTGTCGCCAGACGCTGGCGTCGGAGGCCGAGGCCAGGCTGCACGCACGCTTCCATCTGCGGCCCGGGGAGGATGAGCAGAGATGCGCCATATGCCTCCGCGCACTACCGGAGGGTGAAGCCGGGTCGGGCGCGCGCGCGTGCGCGGCGTGCTACGCGCGCCACGCGGCGCCGCGCAGTGCGCCGGCCGCCGACCACGACTGCCGCCTGTGCCGCCGCGCGCTCGGCTCGCCCACGCGCCTGCAGGCGCACCTCATCGAGCACACGTTCGCGGGTATTGGCGCCTTCACCTGCTACCTGTGCTCCGCGGTGTTCACGAGCGCCGCCGGCTTGCAGCGCCACCTGCCGGAGCACGCGTCCGCGCCCAGACCTTACGACTGCGCAAGATGTGGACTTAAGTTCTTCTTCCGAGCTGAACTTGATAACCACGCGTTCGTGCATCTTGAAGAGGCAGAGATTGCACAACGAGCTTTCTATGAGGCGTACGCTCGCGGTGCTGCGTCAGCGTGGGCCGCTTTGGCACCGCCGGAGCCTCGAACGACTCCACCACAAGCCGAGGTCAAGCGTGAGCCGGAGATCAAAGAGGAGCGAGTAACTGACGAGTATATAGAAGTGTCGTCCCCTCCCCCCGCGCCCCCTCCGCCCTCTCTCCCGGCTGCGACCTCGCCCGCCCCTGTCGTGAAACAAGAGAAGCCTGACGAGGAGTAA
Protein Sequence
MGNLGCCMTSFWGPMGLNTEPVEVRVCGSKQGASKLYEALGSVGSTAGSSWPSSTPEPSPSPASTPTSADAADAEAEPPFTLGATEHTPYQCQFCDKAFPRLSYLKKHEQTHSDQMPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKRDREGREPDRRRALRCLRCGDAFRRPDLLQAHMVSAHGVDTAAMTPPRRVASQPPPTLLACIYCTRDTFTNMEQLQLHVRAAHSALLNGEGPVQVDQPLPTDLSRRAPDEVPPVKRPRSGSGTPQTTLSPSTLLCNQCDAALPDFEAFRAHLKGHIEEGGELRSSPAPCVHCGATFADAAASERHLTAHYLAVSCEYTCHSCARSFAAPDDLQKHLLELHAHHLYRCALCKEIFDSKVAIQVHFAVAHSGENKVWVCRSCGAGAGALRSEAEGAAHVRSRHAAAAPRCACGALLGSGVAARTPRPHRAYRCPVPACNDAFAVQYLLERHMQAHHAMQQQVLNGELPRIKRMDSSNGGEGGDDARSPCTPGADSAGVTSAAVAASDERRRKNGAVALQCAYCGERTRSRAELEAHTRAHSGAAAARHKCLICDEVLPSAAVLAEHKLTHCKVISGDTCSRCRARLLSEESFLAHMARHQPALPAPCVVCRQTLASEAEARLHARFHLRPGEDEQRCAICLRALPEGEAGSGARACAACYARHAAPRSAPAADHDCRLCRRALGSPTRLQAHLIEHTFAGIGAFTCYLCSAVFTSAAGLQRHLPEHASAPRPYDCARCGLKFFFRAELDNHAFVHLEEAEIAQRAFYEAYARGAASAWAALAPPEPRTTPPQAEVKREPEIKEERVTDEYIEVSSPPPAPPPPSLPAATSPAPVVKQEKPDEE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01437318;
90% Identity
iTF_00822228;
80% Identity
-