Basic Information

Insect: Asteroscopus sphinx
Gene Symbol: THAP3
Assembly: GCA_949699075.1
Location: OX453031.1:8071322-8118058[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.29 34 6.4 0.6 1 23 703 725 703 725 0.94

2 10 0.0048 0.57 12.0 1.3 1 23 732 755 732 755 0.93

3 10 2 2.3e+02 3.8 0.3 1 14 759 772 759 784 0.81

4 10 0.0048 0.57 12.0 0.7 1 23 788 811 788 811 0.95

5 10 0.12 15 7.6 0.2 2 21 824 843 824 848 0.93

6 10 0.29 35 6.4 0.2 3 23 901 922 899 922 0.96

7 10 0.0071 0.83 11.5 0.6 2 20 938 956 937 959 0.92

8 10 5.3e-05 0.0063 18.2 3.1 1 23 965 987 965 987 0.99

9 10 0.00041 0.048 15.4 2.8 1 23 994 1016 994 1016 0.98

10 10 0.084 9.8 8.1 5.6 1 23 1022 1045 1022 1045 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.29	34	6.4	0.6	1	23	703	725	703	725	0.94
2	10	0.0048	0.57	12.0	1.3	1	23	732	755	732	755	0.93
3	10	2	2.3e+02	3.8	0.3	1	14	759	772	759	784	0.81
4	10	0.0048	0.57	12.0	0.7	1	23	788	811	788	811	0.95
5	10	0.12	15	7.6	0.2	2	21	824	843	824	848	0.93
6	10	0.29	35	6.4	0.2	3	23	901	922	899	922	0.96
7	10	0.0071	0.83	11.5	0.6	2	20	938	956	937	959	0.92
8	10	5.3e-05	0.0063	18.2	3.1	1	23	965	987	965	987	0.99
9	10	0.00041	0.048	15.4	2.8	1	23	994	1016	994	1016	0.98
10	10	0.084	9.8	8.1	5.6	1	23	1022	1045	1022	1045	0.90

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTCCATAGTTGTTCTAATGATACTAAAAAAACTACCAAAAGCCATGGAATCACATTTCATATGTTCCCTAAAGAGCCGAATCTGCGTACAGCATGGGTGGAGGCTCTTGGCATGGCCAACTGGGAGCCTAAAGATAGGAGCACAATATGTTCAGAGCATTTTAGAAATGAAGACTTTTACGATACCAAGCGAGGGTTACGAAAGATAAAGAGTGGGGCAGTACCTGTAGTGACACAAGATTCTGCAGATGACCTTGACGCGCCGGCCGCATTGAGgATCATGGCCACACTAACAACAATGGGAGAATTAGCTGATCGGCCCTGCCCAGAGGGAGAAGAAGAAGCTTTTGCAGCAATCCTGACTACAATCGACGAAAACTTCCCGGGAGACTGGCGATCATGGGAAGTTTACGATTACACATTCCATGATTTATTTGGATCTGAAGTTTCCTCTAAAATTGAGGGTAAGCTGAGATTCGCTATTCCAACCGCTGATTTAGGCCGTGCATTTGCACCAGACACTAGTTCTTTGTCTGAAAGGAAATATAGAAGTATAAGGACGAAGATCTTGCGTTGGCCCCTGGGACGAGCGTTAGTACATTACCCTCAtcacattatgaaaaaaatacatggcTCAGGCAGATATTATTATGCTTTTGTAGATGCCGTTTACACCATAAGGAGTAAATTGACAAATCGTAGTAGCGCTTCATCTGAACTTCAAACTTCTCAACAAGATCATATAATCTCGGACAGTCCCACACACACAAATACAGAAGCACCCGAATGCTCTACAGGGAGGAAAAGACCTCACGAACCAACTATAGAAGCGGAAAGTACTCCAATAAAGCAACCAACTCCATCCCGAGGACTAGGATGTAATAAAACACCAGCGTTTTGCGCTTTCAAAGTCAATAACCTCTTAGCTAACGTAACACCTACTTGGAAATCAGCTGCCGCTCTCGAAAAACAAGACATGTCACTAAGCGCTATTACACATGGACTTTTGCAACAAAGGAAAATATTTCAAGATTTACTAGATCACCTTCCAcacgaaataaaaaacaaaatcggaAGTGATTTTCTTAATATTGATTCAAAATTTAGGAAGAAATCGGATGATATACTGCAATATGTTTGTGACCGACGTGCAGAGGTCATAGAACAAAAGAGGAGCGCTTTTAAAGTACAAAACAAGGCGCTTAATGAACAACACAACATACCTCCATCAGAGACACATCTTTTTTCTGACGAAGCATTATCCAAAGCAGTTAAAGATTGCTCCAACAATGatgTGTGCAGAGTATGCCTCGCTATGGACACAAAGATGTATCACATAAGAGAATTCAAACTCGATCAGATGTATGAACAAATCACTGGAATAATGGCTAGTTCCGAGGAAAGACTACCACAACGCGTATGTTGGGAGTGTGGCGCTCGACTAGCTACGGCCTGTCGCTTCAGGAGCAAAGCTATTCGAAGCGACGCGCTGCTACATGATCTACTACTGCCTGATACGTATATAAAAATCCGTGACATAAAATCAATAAACCGAACACACCATGGACTAAATACaagtttaatacaaaaaatatacgatGATAGTGACTACGACTTACATATACGAGACATGTATGTAAAAACTGAGGAAACTCCAGAAATCATAGCGAATGACCATGACTCTATGGAGATTGAGGTCAAAGGCCTAACACCTATAAATGAAGTCGAAAATATAGATATAAAAGATGAAAGCAGtaataatgaaaatgaaatattCTTTGAAGAGTACGAccattttgatgatgatgacgataaagTGTTAAGTGAAGTGTGTGGGGAGAAGAAAGAGAAGATACAGAAGATTAAAGTTAAGAAGAAAAAGGGGAGAGCGGTTAAGAAGGTTAAAGCTAAGAAGAttgaggaggatgatgatccgGATACTGCTAGTGACAGGTACAAGAAAACAGACGTAAAACGGAGAAGAACGAACGAGGTACTCGACGAATCACTATTCACGATCAGCTCCTTAACATACGACCAACAAATAGAAGAGATACTAAAAAGACAAGAGAGTAGTAACTACGTGAACGCGCCTTACAAATGTACTGTATGCTATCGAGGGTTCCAGATCCAAGACAGATACACTGCACACGCTGTCAGACATAGCGAGCAAAGCGGTGCCTTCGAGTGTTTTATCTGTAAAACTAGACTGAAGACCAGTCGAGCTCTACGGAAACACTTAACGGCTCAACATACAGAACAATATAGTTGTAAAGGATGCCCATTTGTCACCAGAAATAGCAAACTAACCACGTACATGGGCCACATCCGCATCAAGCACGTGTCGGACTTCGTGTGCGAGCTGTGCGGGTACACCTTCGTCAGCAAGAAGGGCATCGACGTGCACAAGAAGAAGAAGCACAGGCTCGTTGATAAGGCGATGACACTGGAAGGGCCATACTGTGAGGTGTGTGACGTCAAGTTTGTTTCAGAAGAAGCTTACGACAGACATCTGAAGCTATCGTCCAGACACAGTAGTGATCAAGATCCCAACCGCATCCGCAACGACTCACAGAGCATGAATGCGGAACGCAACGGCCGCGTCATGCGACGCATAGAACGCCGCCCCGTCATACACCCGCGCGACCCCGCCGACACTCTACAACACGAACCACACACTCCCGTCAACTGTGAACAgTGCGGTATACAACTGCGCGACCTCCGGTTATACGCGCAACACTTCAGAAGAGCTCACCCAGACAAGAACCGAACCAAGTACCCCGCGATGAAAACCCCCTGCATGTGTGAGCAGTGCGGGAAGATATTCCAGAGCATGGCCCTCTTAAAGGACCATATGTGGGTCCACACGGGCGAGAAGCGCTTCAAATGCGACCGCTGCACCAAGAGCTTCACTCAGAAGACGAACCTGGTGTTCCACATGCGCGTGCACAGCGCCACGCGGCCCAGCTACGAGTGTCCGCTGTGCGGGAAGCACTTCGCCTTCTTCAACAACAGACGGAGACACATGTTTATCCACACCGGCCTAAAGCCCTTCAAATGTGACACGTGCAGCAAATGCTTCACGACGTCCGGCGAACACCGAGCCCACGTGGAGCACGTGCACATGAAGAAACCCTGGCCCAAGCGAGCCCGCCAGAGGGGGGGGCACTGGAAGTGTGACGTGCCCAGCGTGGAGGACTGA
Protein Sequence: MRCSVHSCSNDTKKTTKSHGITFHMFPKEPNLRTAWVEALGMANWEPKDRSTICSEHFRNEDFYDTKRGLRKIKSGAVPVVTQDSADDLDAPAALRIMATLTTMGELADRPCPEGEEEAFAAILTTIDENFPGDWRSWEVYDYTFHDLFGSEVSSKIEGKLRFAIPTADLGRAFAPDTSSLSERKYRSIRTKILRWPLGRALVHYPHHIMKKIHGSGRYYYAFVDAVYTIRSKLTNRSSASSELQTSQQDHIISDSPTHTNTEAPECSTGRKRPHEPTIEAESTPIKQPTPSRGLGCNKTPAFCAFKVNNLLANVTPTWKSAAALEKQDMSLSAITHGLLQQRKIFQDLLDHLPHEIKNKIGSDFLNIDSKFRKKSDDILQYVCDRRAEVIEQKRSAFKVQNKALNEQHNIPPSETHLFSDEALSKAVKDCSNNDVCRVCLAMDTKMYHIREFKLDQMYEQITGIMASSEERLPQRVCWECGARLATACRFRSKAIRSDALLHDLLLPDTYIKIRDIKSINRTHHGLNTSLIQKIYDDSDYDLHIRDMYVKTEETPEIIANDHDSMEIEVKGLTPINEVENIDIKDESSNNENEIFFEEYDHFDDDDDKVLSEVCGEKKEKIQKIKVKKKKGRAVKKVKAKKIEEDDDPDTASDRYKKTDVKRRRTNEVLDESLFTISSLTYDQQIEEILKRQESSNYVNAPYKCTVCYRGFQIQDRYTAHAVRHSEQSGAFECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNSKLTTYMGHIRIKHVSDFVCELCGYTFVSKKGIDVHKKKKHRLVDKAMTLEGPYCEVCDVKFVSEEAYDRHLKLSSRHSSDQDPNRIRNDSQSMNAERNGRVMRRIERRPVIHPRDPADTLQHEPHTPVNCEQCGIQLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCSKCFTTSGEHRAHVEHVHMKKPWPKRARQRGGHWKCDVPSVED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00171821;
90% Identity: iTF_00171821;
80% Identity: iTF_00171821;