Asph014222.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Asteroscopus sphinx
Gene Symbol
-
Assembly
GCA_949699075.1
Location
OX453010.1:9721214-9755319[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 9e-05 0.011 17.5 2.2 1 23 424 446 424 446 0.97
2 20 0.0047 0.55 12.1 0.6 1 20 452 471 452 474 0.94
3 20 2.4e-05 0.0028 19.3 5.6 1 23 493 515 493 515 0.98
4 20 0.00011 0.013 17.2 4.1 1 23 521 543 521 543 0.99
5 20 4.2e-05 0.0049 18.5 5.3 1 23 549 571 549 571 0.97
6 20 9.5e-06 0.0011 20.5 7.4 1 23 577 599 577 599 0.97
7 20 8e-07 9.4e-05 23.9 2.9 1 23 605 627 605 627 0.97
8 20 0.00011 0.013 17.1 6.7 1 23 633 655 633 655 0.97
9 20 0.00011 0.013 17.1 6.5 1 23 661 683 661 683 0.97
10 20 5.5e-07 6.4e-05 24.4 1.9 1 23 689 711 689 711 0.98
11 20 5.6e-05 0.0066 18.1 7.9 1 23 717 739 717 739 0.98
12 20 1.2e-05 0.0015 20.2 7.6 1 23 745 767 745 767 0.98
13 20 2.2e-06 0.00026 22.5 4.2 1 23 773 795 773 795 0.98
14 20 9.8e-06 0.0012 20.5 6.2 1 23 801 823 801 823 0.97
15 20 5.6e-06 0.00066 21.2 4.0 1 23 829 851 829 851 0.98
16 20 3.4e-06 0.0004 21.9 6.0 1 23 857 879 857 879 0.98
17 20 1.3e-05 0.0015 20.1 7.7 1 23 885 907 885 907 0.97
18 20 6.3e-05 0.0074 17.9 6.7 1 23 913 935 913 935 0.98
19 20 0.00082 0.096 14.4 0.3 1 23 942 964 942 964 0.96
20 20 0.35 41 6.2 5.1 1 23 975 997 975 997 0.99

Sequence Information

Coding Sequence
ATGAATCCAGAGCACCATAATATGAATACGGGTGGTGGCCAGCCTCCGGGAAGTTCTGAGTCACAGATCCAAAGAGTTCAGGCAACACAACAGCAGAATAACATGCCTGCCACGACATCTGCTACTGATTTGCGAGTGAACTCGGCAGCAGTGAACGTCGCTTTGTCTAGTGTCGCGAAATATTGGGTGTTTACAAATTTATTTCCCGGCCCGATACCGCAAGTGTCTGTGTACGGATTGCCTGCTGGTGCCAGGATCGAGAATGGAAAGCCTGTACAGtcaTTTCAGGATCTTGGTCAAGCTCATGCCAGTATTTTGAATGGGGATCCGAATATAATACTTGGGCATCATGCAGGACAGTCCCAGGTCACAGTATCCGCTGGAGGCCAGCAGATACCAGTCTCACAGATCATCGCCACTCAGTCTGGAACACATGAAGCGCTTGTGGCCCACAGCCAGCAGGCTGAGTTGGCGGCGGCGCAGGGCTCCGCCAACAACGCGCAGGTGTCAGTTAGTGCTGGCCAAGCCACTCACCAGCAGGTACCCAATAATCGGGTCGAGTTTGTACAACACCATAACATTGATATGGGACACCATACACAACAACACTTAATGCAGCAGCAACTCATGGCCACGGCACGGCCTGAACACAGCAACCAGCAGATCCAACTGACGGTCAGCGAAGACGGTATAGTTACGGTGGTGGAACCTGCCGGCACTAAGATGGTGGACAAGGAGGAATTACATGAAGCCATCAAGATGCCCAACGACCATACACTCACTGTGCATCAGTTACAGCAGATTGTTGGACAAcagGTGTTAGACAGCGTGGTACGCATAGAACAAGCGACTGGCGAGCCAGCCAACATCCTAGTGACGCACAATCCTGACGGCACCACGTCAATAGAAGCCAGCGCCGCCGAAACTCTCGTCGTCAAAGACGAGAACAAGGCCAACAAGATAGATGCCTCACAGTACGCGATACCTACTGACATAAAGGATATCAAGGGAATAGACTTGAAGAGTGTAGGAGCAATGGGAATGGAAGGTGCAGTTGTAAAGATCACAGCCGGCGCATCGGAACACGACATCCATGCTATGTATAAAGTCAATGTCGAGGATCTCTCACAGTTGCTTGCGTACCATGAAGTGTTCGGAAAGCTTAATTCAGAAGGACAGCAACAAACAAAGGTAATAAACGAGAGTGAAGTTGAAGTCGAAGCGGGTACCAGCGCCGCCATGTCGGAAACCGAAACGTCACCCGGCCACCACTCCTGTGATATATGCGGAAAAATATTCCAGTTCCGATACCAGCTTATTGTTCATAGGCGTTATCACGGCGAAAGTAAACCGTTCACGTGTCAAGTTTGCGGTTCCGCATTTGCCAATCCAGTTGAACTGTCGAGGCATGGAAAATGCCATCTTGCTGGGGATCCGAACGAAAGACACGCCAAGAGGGTCGCACAAGACAAGCCATACGCCTGCACTACTTGCCACAAAACATTCTCCCGTAAAGAACATTTGGACAATCACGTCCGAAGTCATACTGGGGAGACTCCGTAcagATGTGAATTCTGCGCGAAGACTTTCACCCGCAAAGAGCACATGGTCAACCACGTGCGTAAACACACGGGCGAGACTCCGCACCGATGCGACATATGCAAGAAAAGTTTCACCAGGAAGGAACACTTTATGAATCATGTCATGTGGCACACAGGTGAAACGCCGCACCATTGTACAATATGCGGCAAGAAGTACACTAGGAAGGAGCATTTAGTGAACCATATGAGATCTCACACGAACGATACTCCGTTCCGATGCGAACTGTGCGGCAAGTCCTTCACAAGAAAGGAACACTTCACCAATCACATATTGTGGCATACGGGCGAGACTCCGCACCGCTGTGACTTCTGTTCGAAGACGTTCACGCGTAAGGAGCATCTTTTGAACCACGTCCGGCAGCACACAGGCGAATCCCCTCACCGATGCAACTTCTGCAGCAAGTCGTTCACAAGGCGGGAGCATCTCGTCAACCATGTGCGACAACACACCGGGGAGACGCCCTTCCAGTGCGGATACTGCCCTAAAGCGTTCACAAGAAAGGACCACCTCGtgAACCACGTCCGTCAGCACACAGGCGAATCCCCACACAAGTGCTCATTCTGCACAAAATCCTTCACCCGTAAGGAGCACCTGACGAACCATGTCCGACAACACACTGGCGAGTCGCCGCACCGCTGTACTTACTGCTCCAAGTCCTTCACGAGGAAGGAACATCTAACTAACCATGTCAGACAGCACACGGGAGAAACGCCACACAAGTGTACGTACTGTCCGCGGGCGTTCGCGAGGAAGGAGCACCTCAACAACCACATCCGACAACACACCGGCGTCACTCCGCACTCCTGCACCTACTGCAACAAGAGCTTCACCAGGAAAGAACACCTCGTCAACCATGTTCGGCAACACACGGGCGAGACTCCGTTCAAGTGTACGTACTGTGCAAAGTCGTTCTCTCGTAAGGAGCACCTCACGAACCACGTGAACCTTCACACGGGAGAGACTCCGCACAAATGTCCCTTCTGCACCAAAACGTTCTCCAGAAAAGAACACTTGACCAACCATGTCAGAATTCACACGGGTGAATCTCCGCACCGATGCGACTACTGCCAAAAGACGTTTACGCGCAAGGAACATCTAACAAATCATCTAAAGCAACACACCGGCGACACTGCGCACGTCTGCAAAGTCTGCGCCAAGCATTTCACAAGGAAGGAACACCTTGTTACGCACATGAGATCGCACAGTTGTGGCGAGCGTCCATTCAGTTGCGGTGAGTGCGGAAAATCGTTCCCGCTGAAAGGAAACCTGCTGTTCCACGAGCGATCACACAACAAGAACAACGCCAATGCCAATAGACCATACCGGTGTGAAGTCTGCTCCAAGGAGTTCCTCTGTAAAGgGCATTTGGTGACCCATCGACGGACGCACACGGAGGTGACCGAAGGTGCCGCGACGGTTGAAACGCCCGCCGAGACAGAAGACTGTACCGACTGCAACAAGTGCATCAAAGTGGAGCCTGAACGAGCCGAGATGAAACATGAAGTCAGGAATACAGTGGAAACTAGGCCAGCAGAAAGCAATGTCGCACAAACCCAACCAAACACTGCTACTGTGATGATTACTAATAATCAGCAAGTGCGTCCCCCGAGCGGGACCGGCACGTTCCCGCACGCGGTGGCGCCGCACCACGCCGGTGCCGCGCTGGCGCACCACCCCGTCACCGTTAACTACTAG
Protein Sequence
MNPEHHNMNTGGGQPPGSSESQIQRVQATQQQNNMPATTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPAGARIENGKPVQSFQDLGQAHASILNGDPNIILGHHAGQSQVTVSAGGQQIPVSQIIATQSGTHEALVAHSQQAELAAAQGSANNAQVSVSAGQATHQQVPNNRVEFVQHHNIDMGHHTQQHLMQQQLMATARPEHSNQQIQLTVSEDGIVTVVEPAGTKMVDKEELHEAIKMPNDHTLTVHQLQQIVGQQVLDSVVRIEQATGEPANILVTHNPDGTTSIEASAAETLVVKDENKANKIDASQYAIPTDIKDIKGIDLKSVGAMGMEGAVVKITAGASEHDIHAMYKVNVEDLSQLLAYHEVFGKLNSEGQQQTKVINESEVEVEAGTSAAMSETETSPGHHSCDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSRHGKCHLAGDPNERHAKRVAQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCTICGKKYTRKEHLVNHMRSHTNDTPFRCELCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTYCSKSFTRKEHLTNHVRQHTGETPHKCTYCPRAFARKEHLNNHIRQHTGVTPHSCTYCNKSFTRKEHLVNHVRQHTGETPFKCTYCAKSFSRKEHLTNHVNLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCDYCQKTFTRKEHLTNHLKQHTGDTAHVCKVCAKHFTRKEHLVTHMRSHSCGERPFSCGECGKSFPLKGNLLFHERSHNKNNANANRPYRCEVCSKEFLCKGHLVTHRRTHTEVTEGAATVETPAETEDCTDCNKCIKVEPERAEMKHEVRNTVETRPAESNVAQTQPNTATVMITNNQQVRPPSGTGTFPHAVAPHHAGAALAHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01030446;
90% Identity
iTF_01030446;
80% Identity
-