Basic Information

Insect: Aspidapion aeneum
Gene Symbol: ZEB2
Assembly: GCA_963576565.1
Location: OY755043.1:10883047-10890398[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 1.7 2e+02 4.7 3.0 3 23 18 39 17 39 0.81

2 26 1.7e-06 0.00021 23.6 2.6 1 23 45 67 45 67 0.97

3 26 5.5e-05 0.0067 18.9 1.2 1 23 73 95 73 95 0.96

4 26 0.41 51 6.7 1.1 1 12 101 112 101 115 0.92

5 26 0.3 37 7.1 1.6 2 23 126 148 126 148 0.94

6 26 2.2 2.7e+02 4.3 2.4 2 23 154 175 153 175 0.95

7 26 0.0031 0.38 13.3 0.8 1 23 240 263 240 263 0.95

8 26 1.2 1.4e+02 5.2 7.1 3 23 270 291 269 291 0.96

9 26 0.0003 0.037 16.5 3.8 1 23 299 321 299 321 0.98

10 26 3.4e-06 0.00041 22.7 3.1 1 23 327 349 327 349 0.99

11 26 5.5e-06 0.00067 22.0 2.1 1 23 355 377 355 377 0.99

12 26 2.1 2.5e+02 4.5 1.6 2 23 407 428 406 428 0.80

13 26 1.4 1.7e+02 5.0 0.9 2 23 436 455 435 455 0.82

14 26 6.6e-06 0.00081 21.7 1.8 2 23 461 483 461 483 0.96

15 26 0.29 36 7.1 3.7 3 23 490 511 488 511 0.96

16 26 4.7e-05 0.0058 19.1 3.1 2 23 518 539 517 539 0.97

17 26 3e-06 0.00037 22.8 1.1 1 23 545 567 545 567 0.99

18 26 4.5 5.5e+02 3.4 1.1 1 15 573 587 573 590 0.82

19 26 0.0013 0.16 14.5 5.4 1 23 630 653 630 653 0.98

20 26 0.0068 0.83 12.3 1.5 1 23 659 681 659 682 0.95

21 26 0.013 1.5 11.4 1.6 1 23 688 711 688 711 0.97

22 26 0.029 3.5 10.3 0.2 1 23 718 743 718 743 0.96

23 26 0.0001 0.013 18.0 1.6 3 23 752 772 751 772 0.98

24 26 2.8e-05 0.0035 19.8 2.7 1 23 780 802 780 802 0.96

25 26 0.024 2.9 10.6 0.4 1 23 808 830 808 830 0.95

26 26 4.1e-06 0.0005 22.4 2.0 1 23 836 859 836 859 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	1.7	2e+02	4.7	3.0	3	23	18	39	17	39	0.81
2	26	1.7e-06	0.00021	23.6	2.6	1	23	45	67	45	67	0.97
3	26	5.5e-05	0.0067	18.9	1.2	1	23	73	95	73	95	0.96
4	26	0.41	51	6.7	1.1	1	12	101	112	101	115	0.92
5	26	0.3	37	7.1	1.6	2	23	126	148	126	148	0.94
6	26	2.2	2.7e+02	4.3	2.4	2	23	154	175	153	175	0.95
7	26	0.0031	0.38	13.3	0.8	1	23	240	263	240	263	0.95
8	26	1.2	1.4e+02	5.2	7.1	3	23	270	291	269	291	0.96
9	26	0.0003	0.037	16.5	3.8	1	23	299	321	299	321	0.98
10	26	3.4e-06	0.00041	22.7	3.1	1	23	327	349	327	349	0.99
11	26	5.5e-06	0.00067	22.0	2.1	1	23	355	377	355	377	0.99
12	26	2.1	2.5e+02	4.5	1.6	2	23	407	428	406	428	0.80
13	26	1.4	1.7e+02	5.0	0.9	2	23	436	455	435	455	0.82
14	26	6.6e-06	0.00081	21.7	1.8	2	23	461	483	461	483	0.96
15	26	0.29	36	7.1	3.7	3	23	490	511	488	511	0.96
16	26	4.7e-05	0.0058	19.1	3.1	2	23	518	539	517	539	0.97
17	26	3e-06	0.00037	22.8	1.1	1	23	545	567	545	567	0.99
18	26	4.5	5.5e+02	3.4	1.1	1	15	573	587	573	590	0.82
19	26	0.0013	0.16	14.5	5.4	1	23	630	653	630	653	0.98
20	26	0.0068	0.83	12.3	1.5	1	23	659	681	659	682	0.95
21	26	0.013	1.5	11.4	1.6	1	23	688	711	688	711	0.97
22	26	0.029	3.5	10.3	0.2	1	23	718	743	718	743	0.96
23	26	0.0001	0.013	18.0	1.6	3	23	752	772	751	772	0.98
24	26	2.8e-05	0.0035	19.8	2.7	1	23	780	802	780	802	0.96
25	26	0.024	2.9	10.6	0.4	1	23	808	830	808	830	0.95
26	26	4.1e-06	0.0005	22.4	2.0	1	23	836	859	836	859	0.97

Sequence Information

Coding Sequence: ATGGCCCTCCAAAGGCACATTAGTGTTAAACACCTGAATAAGGTAGAATTTTGCGAAATTTGCAATAAAACATTTTCCTGCAAGGAGTACTACGATCTTCACTATACACAGTATCACAGCGATAAGAGTAGATTTTGTTGTGAATACTGTGGCAAAGAATTCTACACACAAAATAACTTAAATATTCACTTACGGATTCATACCGGCGAGCGTCCATATCTGTGTGGAGTGTGTAACAAAACTTTTAATAAGTCGGAAGCATTACATATTCACCAGCGGGTTCACACCAAGGAAAGGCCGTATACCTGCGAATATTGCAGCAAAGGATTTACTCAAGGTAAAGAAATACCAATTTCAGATCATCCTAAATTTCCATACTGCCACCTTTGTGACAAGTTTAGTAATTCTCGCAATGCATTTTACTATCATGTTAGAGCAATCCACTCGGAAAAAGATTTAGTGTGTGAATACTGTTTAAAGTCATTTCTATATTGTAATCAAATGGATGCCCATAAGAAAACACATCTAAAACACCTAAAGTTAGGAACGAAACCAAAAACAACCACTTGTCCCGATTGTGGCAAAATAATATGGGAAATGTTCCTTAGACGTCATAGAACCAGAGAACATAATGTACCCTATGACTTTTGTGAAATATGCAAAAGCAAATTTAGAGATATTAAAACTCATATGGAAACCGAACACGAAGGAGTGAAATACATCTGCCAATATTGCAAACAAGAATACAGTACGGAAACTCTTCTTAAATATCACATTGATATCAGACACCTCAATGAagaagaattttgtaaaatttgcaataaaaaatttacctgCAACTTGTACTACAAGAGGCACTATAAAAAATTTCACTGCGGCAAAGAACTACGTACTTATTGCTGTGAACAATGTGGCAAAGAATTCTCACTGCAACATAGATTAACTGTTCACTTACGGATTCATACGGGCGAGCGTCCTTATAAGTGTGAATACTGTAAAAAGACCTTTAATAGGACGGATTCATTACGCATTCACAAACGGGTGCATACCAATGAACGACCGTATACCTGCGAATATTGCAGTAAAAAATTCACTCAGGCTCAATCTTTAAAAGTTCACAAGCGGATTCACACGGGAGAGAAACCTTATAGTTGTAAAGAAgcacataaaaaaatacatttaaaaaaattgaatgaTCAAAAACCGCCTGAAGAAACCACTTGCCCTGATTGCGGTAAAAAGCTGTGGCGGGAATTTTTGAATCGCCATAGACACAAAGCGCACAACGTACCCTACGATAAAACCTACTGCGAAATATGCAACCAGAATTTTACGAAACTCAAAAGCCATATCGAAACGATGCATCAAGGAGTGACAAACAGCTGCgaaatttgcaaaaaaacatTCTCAACCCGTGGAAACCTAAATTTGCACACCAGATCCACGCATGTGACCACGGAACAAATTTGCACTATTTGCAATATAAAATTCTCTTGTATCAGAAATTATAGAAGGCATCTTAAAAGGTATCACGAAGGACCAGTCAGTACAGTCTGTCATCACTGCGGCAAAACCTTGGCCACCAATCGAGCATTGACCCTTCATTTACGAACCCACACTGGTGAACGCCCATACAGGTGTAAAATCTGCAATAAAAGCTTCACTAGACCAGAAATCCTAAAGACTCATTTACGCGTACATACGAAAGAGAGACCGTACCTTTGTGAATTCTGCAGTAAAGGCTTTACCCAGTTTCATGATAACCAAAGAATGTTTAATTTTAGTAATGAGGATGTTCAAGAATGTCCGTTGTGTGGAAAGTGGCTTCGTGCAATCTATGTTCACGCCCACATGCTTATTCACAAGGAAAAACCTTCCAAGCTACAATTTCAATGCAAAAGATGTGAGAAGCAATTTGTTGTGAAGGCGCACCTTATTAAACATCACAAAAAGGACCATCAATTAGACAAGCCGTTCCCTTGTGATCTGTGCGATGAACAATTTGTTTCGCATAGCGCTGTGGATGCTCACAAACGAAAACACCACACTGATAATCTCGCCTACATTTGTGATCATTGTGGAAAGAAGTGCCTGTACCAGGGAGAATTGGATCAGCACATCAAAGTTGTCCACGAACGAGTCGTCCAGACGTTTCCATGTCCGAAAGAAAACTGTAACCGGATTTTCAACTATGGCGGTTCCCTCAAATATCACCTGTTAAGTGCCCACGTagaagaaaataacaaaaagttttgTGACATGTGCGCCAGGTCATTTAATAATCCTTATCTTTTCAACCGCCACATGAAAAAACATGCGCGTGGAGGACCTGAAAAACATGCCTGTCATCTTTGCCCGAAAACGGTCACTTCAAGGTCAAGTTTGCGAGAACACATTAGAATGCACACCAATGAGAGACCGTTTATATGTGAATATTGTAGCAGAGCATTTAAAATCGATAGAACCTTAAAAATGCACTTGGTCGTTCACACCAAAGAACGCCCATACAAATGTCAATTTTGTGATAAAACTTTTACTCAACCCAGCCCTTTAAAACGACACAAGCTGAAAATTCATGCAGATTTATTGGCCAAGACTTAA
Protein Sequence: MALQRHISVKHLNKVEFCEICNKTFSCKEYYDLHYTQYHSDKSRFCCEYCGKEFYTQNNLNIHLRIHTGERPYLCGVCNKTFNKSEALHIHQRVHTKERPYTCEYCSKGFTQGKEIPISDHPKFPYCHLCDKFSNSRNAFYYHVRAIHSEKDLVCEYCLKSFLYCNQMDAHKKTHLKHLKLGTKPKTTTCPDCGKIIWEMFLRRHRTREHNVPYDFCEICKSKFRDIKTHMETEHEGVKYICQYCKQEYSTETLLKYHIDIRHLNEEEFCKICNKKFTCNLYYKRHYKKFHCGKELRTYCCEQCGKEFSLQHRLTVHLRIHTGERPYKCEYCKKTFNRTDSLRIHKRVHTNERPYTCEYCSKKFTQAQSLKVHKRIHTGEKPYSCKEAHKKIHLKKLNDQKPPEETTCPDCGKKLWREFLNRHRHKAHNVPYDKTYCEICNQNFTKLKSHIETMHQGVTNSCEICKKTFSTRGNLNLHTRSTHVTTEQICTICNIKFSCIRNYRRHLKRYHEGPVSTVCHHCGKTLATNRALTLHLRTHTGERPYRCKICNKSFTRPEILKTHLRVHTKERPYLCEFCSKGFTQFHDNQRMFNFSNEDVQECPLCGKWLRAIYVHAHMLIHKEKPSKLQFQCKRCEKQFVVKAHLIKHHKKDHQLDKPFPCDLCDEQFVSHSAVDAHKRKHHTDNLAYICDHCGKKCLYQGELDQHIKVVHERVVQTFPCPKENCNRIFNYGGSLKYHLLSAHVEENNKKFCDMCARSFNNPYLFNRHMKKHARGGPEKHACHLCPKTVTSRSSLREHIRMHTNERPFICEYCSRAFKIDRTLKMHLVVHTKERPYKCQFCDKTFTQPSPLKRHKLKIHADLLAKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -