Basic Information

Gene Symbol
Prdm4
Assembly
GCA_017141405.1
Location
JADHZF010000028.1:538957-543683[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 8.7 1.4e+03 0.8 5.1 3 19 659 675 657 680 0.87
2 7 6.7 1.1e+03 1.2 0.1 1 19 691 709 691 714 0.72
3 7 0.13 20 6.6 2.0 1 20 720 739 720 741 0.93
4 7 0.00018 0.03 15.5 2.8 3 23 754 775 753 775 0.97
5 7 0.01 1.6 10.0 0.9 1 23 785 808 785 809 0.96
6 7 6.1e-07 9.8e-05 23.3 1.6 2 23 817 838 817 838 0.98
7 7 6 9.5e+02 1.3 5.8 1 23 844 869 844 869 0.96

Sequence Information

Coding Sequence
ATGCCGAAAAAAACTAACAGACATGTGAAGGATTCAGGGACAACGAGGAGACAGCATATTGTTAATAACGATTGCAAGGATACTCACGTCAAACATACACACAATTTATGTATTGACGTTAAAAATGCTAAGAGGTGGTTCACGTTGAAAAAACGTATGGGATTTGAGGAGGATGATGACTTGGTAGTCCATTTGCTTGATCTTGCCGAGACAATCAGAAAGAACGACAAATCTTCAGAGAAAAGTCCGAGTACGAATGGCAATGCAAAGGAGAAGCAGAAAATTAAAAATAATGTCGAGGCGGAGCCTCACGAACCGCTTCGTCGAAGCTCACGTAAACAGAATCAAGGATTTCAAAGTAACGAAAAATCTCTTAAAATACAAATATCAGACAAGGCATCAATGGAGATTAAAAAGAACACGGATGAGGAATTGGCTAAGCATAAAATGAAAATAAAACATCACAGGACTAAAACAAAACAACATAAAGAGAAACGCAAAAGACGAAAGCACAGTAAGATCATTGAGTCTGAACAATCTTTGACAATTGAAAACTATAATACAATACAGCGTGATGAATCTGATGACAGTATAGAAGACACTGAGAATACTGTTAAATTGAACAAAACCTCTCAAGCCCAGGAACCGAGAGATGAATCTGTTATTCAAAAGACTGAAACTATAGATAATGTAGTATTAACCAGCAATATAAATAGCAAAGAGAATATAAGTCAAAATTCCCAAATAAATGACAACTTAACGGACAAAAATACAACGATTCAGGAAAATAAAAATTTAAACAACACTTTTTCAACAAAGTGTTCGGTGGTGAGACACGTTATAGAGCCCAACATTTCCAAGGATATCAACCAAAAATCTGAAAGATTAGAATCATCGAAGCACGATAAAAAGTCCTCATCCATAAGACCAATAGGAACGGAGAATAAATTTACAGAGCCTGCAGTAAAACCTGAAGGCGATAAGAAAAAGAAAAAAAGGAAACATCATCTAAAACATGAAGCGGAAGTCGTACAGAGTGATTCAAATACAGAAACACCTACTGACGATTCTGGCCACAATCAGCGTAAGAAAAAGCACAAAAATGTAGAGCACAAAGGTAAAAAAAATCACGACGTGAGGAAAGCGCCGCAGGATGGAATGGTTCCACTTGAGGCCCGCAAGCCGGACCTTAACAACGCCTCGGGTCCACTGGAAGCCCTACCTCAAGGTGATTATGATACTGAAGCTAGCGAAGAGCATCATAGGCTTGCTATAAAAATCAAACTCTGCCAGGATTGCAATAGCCGTCACATTCAGGATGCCTGCCCCCTAACCTCAGCAGTCTACGAAATTCCAGATTCAATACTCTACACTGACTGGATAAACATGCAGAAGCGTAATCCTGAAGTGGTAAAAGCCCTTAACACTGAAAACCCGATGTCCGAAGGTTATGGAAAAGCAGCTGATGATGGATTTGAATCAGATGAAGAATCGGATCAATACAAATCGAAAAGTCAGACAGAAGAGAAACGTCTTCAGATCGACCAAGAGCGACCACTATATTCCAGAGATTCCCTACCAGATTGTCTAGAGCTCAAAATCACAAATAATGAACACGGTCTTGGAGTATACGCCAGGAATTTGATGCCAATATATGCGAAACTGGGTCCATTAATAGGTGAACAAATAAAGGAAATGGATATTCCCGATGACTTTTCCATGCGTCACATTTGGGAGACGGAGAATGAGGGAAAAACCCTCTATACAAGTACAACAAATCCCTTAAAAAGCAATTGGATACGTTACATAAGACCTGCCGAGACAAGAGACGAAAGAACTGTGGCAGTAATAACTCAGAATGGTAAACTTTATTTCGTTACAACGCAAAATATAAATCCAGGGAGCGAATTAACATACTGGGCGGATTCTCAGTCGTCTGCATGGACTCGAAAGAATAAAACAGATAAGACAAATTGCGGCGGTTGTAATCTTAACTTTACACATCCAATTTACTATCGTTTACACTGCTGCATATTCCACGACACCAATTACAGTCTAACTATACGTAAATATCATTGCAAAGTATGTGGTGCTGCTGTATTAGGAAAAGATAATATCATGAAACATGCTGCAGAACTCCACGCGGGTCGTGGAGCCTATCAGTGCCAGTACTGCAGGAAATTCTTCCTTCGTTTAAATTATCTTGAAATGCACAGGACTTATGGTTGCGCACAAAATCCACAGAGGTCTAGGCCATTATGCGACTTTTGTGGACGTAAATTTTGTCAACCCCAGAAATTAAAAGTACATATTAAAAGAATGCACAGTGATATGTCGGAGGTACTCAGAGAGTTTCAATGTAAACTCTGCCTGAAATTATTGGGATCCAGGGCTGCATTGCAACGACATATGAAGGAGGTGCATCACAAGGATGTCGTGGGTGCAGCAACTTGTGATAGATGTGGAAAAATGTTTCAAAACAAAAGTAATCTGAAAATTCACATGTTGACGCACAGTGGCGTTAAACCATTCAAGTGTAAAAAAAGTAGTTGCAAGGCTGCATTTACAACAAAGCAGTGTCTTCAATTTCATTACAAAAAAGTTCATGGGTTGACGGAAGAAATGATGCCGAAAATCGAAAGATCAGTTGCTTATACGTTTGACGCATACAGTGGTGGTCCGTTAGAAGAGACATCCCCAGAGAATATTCCGCAACCAAGTCGCAGAAATTCTCAGGTAGAAAACAGCAACGGTTTGTTATCAATGGATGACGTGAGTTCTGAGAATAGTATGAAGAATGAGACACCAATATCATCATCTCTGTCAGTTCCTCCAGATATTGACTCTGAGACGCCAATCAAAAATCCCCCCGGTGAAGATATGCCATCATCACCTAGATCTGTAGTTATTCACCATAAAATACCCCTGGAGTCACCGATTCGTCAGGACCTGGATATGTACAGTACTTCTAAGATGCAGAGTAAGGGAAGTAAGAAGTGGATGGGTGAATTCAATCTACCAACGACCAAGCTCCCAGAATCCACACATTCAGTCTTAGTCACACCAACTGATGTCTATGAATTCGAGCCGAGTCCGAAAAAAGATGAGGAACATTCACCTCCTCTCCCAATGACCTCATCCCTCATGAACGATAGTAAACTTGGCTTGAGTGTCTACAGAAGAACTGAAAGTACAAATGCAAGCCTTTTAGTGGAGGCCGCTCTAGATGCAGCAGAACGAGACATTGGTGCTGTATCTAGTCCAATCCTAGAGGATAATGACCGAGATGGTAATCTGTACTCAATTACCAATCAAATGCATTCCCCTCTACCCGCAAGATCTCCAGACGGCCACTTGGATTCATACATGCAACAGGAGGATCTGATGCATCCCTCCCCAATCACAGATAACAGAAATTCTCCACCAAGTCACACACATACGGATTATCATCTCCATCGATCTGTCGACTACATAAATTCCAACAGACCACATAATATTGAACAATATCTCCATCATGACGATCTTCCTCGAGGCTCATCACCCAATACATACATTCATATGACACAAACGGATCTTGGATCGCCATCAGCCACACCAAATCGCTATCAAGAAGTGCATCACCACCACCATCATCATCATCACCAAGGGCCCACGGACAATCTCTCCAGTGACGAGGGTGACTCTGTTGCTCAGAATCTGAGTATTTCAGTCAAGGAGAAGGCTCTTCAGTTGGATCTATCGACGTCATATAAATACGATTCCCTCGATTTTGAATTCGGTAATAGGGAGCGCAACTTGGAACCATTGGTGTTGAATAATGGTGAACTTCAGGGACTCGACATGAGTGCCCGCGGATTCCATGCTTTTGGAGCTCAAATGCAGAACAGCAGATATCACCACCATCATCTTTACGATATTGGCGAACGCCAGAGTGTCGATTTGAGCAGGACAGGAAACTATTCGATATCACCACCACCACCTCCACCTCCCTATCCTCACAATGATGTTCTAAGGGTTGTTAGTCTCGATCTCACGCCTGGCGGCCGACATAGTGTCGATTTGAGTCTCTCGAGGAGCCATCATATTCATGGTAGTACATCGAGAGTACTCCCTAGTCCACAACCAAGTCCAACGACACAGCATGTTGTGTCTGATGCTATTGACGGACGAATGATATCTTCACCACCTCCTTCATTGCCTGCTTACAATCCAACTTATCCTGTCAGTCCTGCACCTTATCATCCACCGAGGCCTGGGTATTATCACCATTCTGGGTATTATTAA
Protein Sequence
MPKKTNRHVKDSGTTRRQHIVNNDCKDTHVKHTHNLCIDVKNAKRWFTLKKRMGFEEDDDLVVHLLDLAETIRKNDKSSEKSPSTNGNAKEKQKIKNNVEAEPHEPLRRSSRKQNQGFQSNEKSLKIQISDKASMEIKKNTDEELAKHKMKIKHHRTKTKQHKEKRKRRKHSKIIESEQSLTIENYNTIQRDESDDSIEDTENTVKLNKTSQAQEPRDESVIQKTETIDNVVLTSNINSKENISQNSQINDNLTDKNTTIQENKNLNNTFSTKCSVVRHVIEPNISKDINQKSERLESSKHDKKSSSIRPIGTENKFTEPAVKPEGDKKKKKRKHHLKHEAEVVQSDSNTETPTDDSGHNQRKKKHKNVEHKGKKNHDVRKAPQDGMVPLEARKPDLNNASGPLEALPQGDYDTEASEEHHRLAIKIKLCQDCNSRHIQDACPLTSAVYEIPDSILYTDWINMQKRNPEVVKALNTENPMSEGYGKAADDGFESDEESDQYKSKSQTEEKRLQIDQERPLYSRDSLPDCLELKITNNEHGLGVYARNLMPIYAKLGPLIGEQIKEMDIPDDFSMRHIWETENEGKTLYTSTTNPLKSNWIRYIRPAETRDERTVAVITQNGKLYFVTTQNINPGSELTYWADSQSSAWTRKNKTDKTNCGGCNLNFTHPIYYRLHCCIFHDTNYSLTIRKYHCKVCGAAVLGKDNIMKHAAELHAGRGAYQCQYCRKFFLRLNYLEMHRTYGCAQNPQRSRPLCDFCGRKFCQPQKLKVHIKRMHSDMSEVLREFQCKLCLKLLGSRAALQRHMKEVHHKDVVGAATCDRCGKMFQNKSNLKIHMLTHSGVKPFKCKKSSCKAAFTTKQCLQFHYKKVHGLTEEMMPKIERSVAYTFDAYSGGPLEETSPENIPQPSRRNSQVENSNGLLSMDDVSSENSMKNETPISSSLSVPPDIDSETPIKNPPGEDMPSSPRSVVIHHKIPLESPIRQDLDMYSTSKMQSKGSKKWMGEFNLPTTKLPESTHSVLVTPTDVYEFEPSPKKDEEHSPPLPMTSSLMNDSKLGLSVYRRTESTNASLLVEAALDAAERDIGAVSSPILEDNDRDGNLYSITNQMHSPLPARSPDGHLDSYMQQEDLMHPSPITDNRNSPPSHTHTDYHLHRSVDYINSNRPHNIEQYLHHDDLPRGSSPNTYIHMTQTDLGSPSATPNRYQEVHHHHHHHHHQGPTDNLSSDEGDSVAQNLSISVKEKALQLDLSTSYKYDSLDFEFGNRERNLEPLVLNNGELQGLDMSARGFHAFGAQMQNSRYHHHHLYDIGERQSVDLSRTGNYSISPPPPPPPYPHNDVLRVVSLDLTPGGRHSVDLSLSRSHHIHGSTSRVLPSPQPSPTTQHVVSDAIDGRMISSPPPSLPAYNPTYPVSPAPYHPPRPGYYHHSGYY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-