Basic Information

Gene Symbol
HIVEP2
Assembly
GCA_017141405.1
Location
JADHZF010000252.1:206259-212275[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 4.4e-05 0.007 17.5 0.6 1 23 78 100 78 100 0.98
2 9 0.013 2.1 9.7 2.1 1 21 106 126 106 130 0.86
3 9 0.0034 0.55 11.5 1.8 1 21 306 326 306 327 0.96
4 9 9.8e-07 0.00016 22.7 1.6 1 23 932 954 932 954 0.99
5 9 4.2e-06 0.00067 20.7 5.1 1 23 960 984 960 984 0.92
6 9 1e-05 0.0016 19.5 1.0 2 23 1437 1458 1436 1458 0.96
7 9 0.00053 0.084 14.1 1.8 1 23 1464 1488 1464 1488 0.92
8 9 0.00072 0.11 13.7 2.7 1 23 1509 1533 1509 1533 0.93
9 9 0.035 5.5 8.4 0.7 1 19 1638 1656 1638 1661 0.92

Sequence Information

Coding Sequence
ATGACCGACCCACAACTCACCAACAATAACAACAACACAAGTACAAACAACAACAACGATGGCGAGCCCAAGTACCTGCACAAAAAGTTCAAGAAGATGGCAACGACTGAGGTGGTGGCACCCCTGGAGGTCGCGACGGAAGCACCAGCACCACCACCTGCTCCAGATCCCAAGGACCTTGATTCATCCCAAGCATCACCATCTCCCCCAGACGAGTCACGAAAAACAGGTTACGTGTGTCCATATTGCAAGCTCTCCTGCGCTAAGCCTAGTGTCCTCCAAAAGCACATCCGCGCGCACACAAATGAGCGTCCCTATCCGTGCGTTCCCTGTGGTTTTGCTTTCAAAACGAAATCGAACCTCTACAAACACTGTAGATCACGTGCACACGCCTTAAAAATGGAGGGTACTGATACAGGCAAAGTATCCGAAGACTCCGACATGAGCCTCTCTGATTCCGCTAGCAACGGGACAGGTACTCCGCCTCCTCCTCCGTCTACCCCATCTGTGAATACCCGAACCATAAAGACTGGAAAAATATACAAACCAAAGTTCCACACGGCCCTGCAATGCGTCAATGACTCGGAAACCCCGCCTTCTCCAAGTTCCAACAGTTCTCCAGCCTCTCTGAAACATGAACAGCTCCAGGAACATATAGATAGAATCATCACCGATAACCAGGCCATTGTAGATGCTGTGGATCCACGACTGCACAAGCTGATGCAACGCCAACAGAGCTTGGTAGATCAGAAATCAGAACAACCTTTGAATCTGTCAGGGGATGAATGTCAAACACGAAAACGTTGCTACAGTGAAAGCTTTGCTCAGGAAAAGCCGAAATCAAGTACACCAAATGGCGAAGGCTCCATTATCAAAGACCTCCTGCTGAAAACAAAATCGCAGGTTCAAGAAGAATTTACTTGTTCATCCTGCAGGATTTCTTACACAAGTTGCGATAACTTGGAGGCACACAGGAGGTACTATTGTAAGGGCTCTCCGAAGGACTTCCAACTGGACCTAGAGAAGAAGGAAGATTTGGAGAAAAGTGATTATTATGCAATTCAGCCTCTCCCTTCACCAGGTCCTCTTTTGGGCAACACAAGGCTGGTGGACGCTTACGCTCCGCCTACCAAAAAAGTTCGTGAGGTAACGACTCTTCGGTCGTTAGAAGAGCTTTCAAAGTATCCCAGACCAAACTCCCTTCAAATGTTCGGGGGGGAAGTGAGAATCCTCGATAACACGGGTGAGACCAAGACTATGAGGATCGAGCCTCGTCAGTCCAACTCGCCACTTAGTGATCATAATCCAAGCAAATGTGCAACTACAGAAACTTCTTCTATAGTTGTCCGATCAGGGCTTCACTCCGGCGGTACTATGGTACATAAGCCACCTGGGACGCCTTCAACCACCCCAAGCACATCTATATCTATTCCAAATACGCCAAAAATTTTGGCGCCAATCATACCAAACATATCAACTCCTAACATAGCCCCAACCATGTCTTGCTACAGTTACCTAGAGCCTCATTTAAATCCTTTGACAAGTATCACTGCATATAATCCTCTGACCTTACCCCAAGCAGGGATAGCTGGTATTCTTCATGGGGGAAAGGTGATACCATATGTTCCAGGGATGCCGGGACCCCATACTTTATCAAGTATGGAGATACCTGTGACTACTGGTTCCAGCTACAAGGTCATTCCGGGAGTACCTGGGCTGCACATGGTACCCCTGGACTTGGCCAGCCCAGTTAGGACACCAAGCGTTCCGGGTATACCCGGTCCGGCGTCAAATTCAGGAATGAGTGTTGGGCCCCTCGACCTCGCTAGTCCGAGGGATCCTAAAACGTTCAAAAGCCCAAATGGGATAATTAGCCCCAAAGTTCCTGCGAAGCTCGAAGAGAAATACAAAAGCAGAACTGGAAACTTGGTAAATGAATCTACAATCGAAGAAAGATCCCCGAAGAGCGTGGGCAAATATAACATTTTGGAGGACTCTCAAGTGATCGACAAAGAGTTTGGCTATTCAAATGGAGGTGAGTCCGGTCACTCTTTTTCAGATCCCCCACTGAACTTTGATTCCCAGGAAAATGGAGTAGTCAAAATGTCTTCCCCGGAACCGTTTGTGCCCAATGGTAGAACACGATCAGAAAGTACCCCCGTGATTGTCATGAATCTTGATCCTCCAGAAAGGTTCTCAGACAAATCTCCCGATGCCAGGCAATCACCTATTGAACATCAAAAACCCGAAGGAGAGCAAAATCCAAAGTTCTTGCGACCAAGTTCTTTACCATTGAAACCAGGAACGTTCACTCCTAAGAAACATCATGGGATCACGCCAACAGCAAACACTCTCCCTTTGATAAGTCCTGAGACTCCACGACCAAAGAAATCATACGGTCAACTCTACTTGAACGGACAGGCCTATACATACTTAGGTCTGAAATGCTCAACTAAAGTAATCTACTGCACACTGAATCATCCACAACCTATGTACGTAAACCAGCAGCACGGACTGAGTATGTATTCCAACTGGAAGATTTGTAAAGAATCACCACCCGATATGAACCTAGCTCATTATGACTCCAGACATCGGCCTTCAAATTATACGGTAGCTTGGAAGAAACAGGAGGACATTCTAACACATTCGTCACAGCGTCCAACCACTCCGACGAGTCCAGACAGCGGTCTGGAGAGTGATACTCAAGAAAAGACCAGGAGAGTAAAGATATTCGATGGAGGGTTCGAGTCAAACGAAGATTACACCTATGTTAGAGGACGAGGCCGTGGAAGATACGTCTGCGAGGAATGCGGAATCCGTTGTAAAAAGCCTTCGATGTTAAAGAAACATATCAGAACACATACCGATGTTCGGCCATATACCTGCAAGCACTGCTCCTTCAGTTTCAAGACAAAAGGAAACCTGACTAAGCACATGAAATCAAAGGCCCACTACAAAAAATGCGTGGAGATGGGAGTGACACCAGTGCCAACGAGTGTTTGTGATGAGAACATAGATAAAGAAGCAATAGCAAGGTTGGTTGCTGGAGGGGCCAATGAGGAATCGACTGATGAAGACGAGGATTCTGAGGGAGACGAGAGTGACGAGTCTGGAAGTGAAGAGCATGAAGCAGCCCAAAGTCTTCTAAGTCTGTCCCAAACTAGCTCGAAAAGACTTCCAGGATTGCTCCCTTCAGGAAGGCCTACAACGTATCCCTACGCACTCAATTTTCCGACCACAACCGTTACAAGTTCAATAGTTTCTACTACCCCTGTCACTTCTACAGTAAGCGTAACGTCTACGACGATAATTCAATCTGAAGTTTCAAATAGGTATTACTTTCCATCGAAAAAGGTGGCAGAAGAGCCTAGGGACAGTGTGATCCGATCCTCCAAGGTTGATGAAGACGTAGAAATGGAGGAGGTCGAGGTGACGAGACCAATGGACCTCACCACTAGGACACAGTCCCCCAGATCGAGAGATATTCTCACTCCTGTATGTGAACCAGTGCTGATGCAAACTATTGTACAGACGATGGAAAGATTGCCTCCTCAGGGAAGAGAGTGGAAACCCGAAGCTGAGGGACAAATGCTTCAGGCTTATCTGAAAGAGAGACATGTCATGAATAGTAAGATGAAGCTACAGTTTAGAGTAGGAACATCAAAAAATGACAAGAAAGTTGTGTATTCCGAGGAATTTGGAGGATCCAGGGGTGGATATTCTGGAGTAACACCCCTGGTAACGTATACTGACCCCAGTAGGATGCAGATGGAGATGCGGCAGGAGGAGGAGGTTAAGGTTGAGGGGCGGGAGAGGAGGCCCTTTGATATTGAGTCGTTGCATCTCGAGAGGGATGACACCATGAAGCATGAGTTCGGAGTGGGACAAGGGGAGATAGTTCAAGCTGTTAGGGTTGGCTTAGAGAGATTTGAGCGAAATGGACGAATTGAACGACCGCCCAGTCAGGAATTCAAACTACCGAGTGAGATAAGGGCTCCGGAGTTCAAGGAGGGTACTTCAGGGGAGAATAGGGAGTTCAAGGCTGAACATAGATTGCTAATTGAGGGAAATAAAATCGATATGCCAAATTGCCCTAGGATAGAGCTGAGGGACCATGGGGTGAACATCAATGAACTGGCTAAGAGCATAGGTGAAGGGATGAAGCATGTGGTCGCAAGGAAAATGGTGGTTGGGGGCCCTGGATTCAGGTCCACGTCGCCAAACCCTGGGAAACCGCAAGCAGAGTTCCTCCAGCCCAGTGGAGGACATGGATCTAATTATGGAAGCGTTAATGAGGAAGGTCGTAGTGTATGTGGTTTCTGCAACAAAGTATTCAATAAACCAAGTCACTTACGTCTCCATATTAACATTCACTACTTCGAGCGTCGATTTAGGTGTGAAAGCTGTGCAGTTTCATTTCGAACTAAGGGCCATTTGACAAAACACGAGAGATCCGTATCCCATCACAATAAAGTGAGCATGACATCGACATTCGGTGCTGCAACTGAAAGCAATCCTAGGCCATTCAAGTGTGAGGATTGCAAAATTGCCTTCAGGATACATGGGCACTTGGCTAAACATCTTAGGAGTAAAATGCACATCATGAAGTTGGAGTGCATTGGCAAATTGCCATTTGGAACTTACGCTGAGATGGAGAGGTCCGGGGTCAATCTCAATGATATTGATACCACGGATTGTGATAATAGTCTTGCTAGTCTACAGATATTGGCCTACAAGTTGTATGAAAAGGATCCGAGTAAGATGGGCCAATGGGACCCCGAGATGGGTCCTCCGAACATAGCAAGTGGTGGTGAGACCTCATCAGACGAGGCATTAGTTAGTACAAATGATGCGAAGCAAATCAGTGATGTACATGTGCCAAATGCCCACTTCGACGACAATCCATTGCCCTACAAGTGCCAAATGTGTCCCCAGTCCCTCAGAACAGTCGGTGATCTCCAAGTACACTGTTACATGGAGCACAGTGATCGAGGAAAAGAAAATACACAGTCCCGAATCAATGACGAGGACCAGTCGAGACAGAATGACGATACGTAG
Protein Sequence
MTDPQLTNNNNNTSTNNNNDGEPKYLHKKFKKMATTEVVAPLEVATEAPAPPPAPDPKDLDSSQASPSPPDESRKTGYVCPYCKLSCAKPSVLQKHIRAHTNERPYPCVPCGFAFKTKSNLYKHCRSRAHALKMEGTDTGKVSEDSDMSLSDSASNGTGTPPPPPSTPSVNTRTIKTGKIYKPKFHTALQCVNDSETPPSPSSNSSPASLKHEQLQEHIDRIITDNQAIVDAVDPRLHKLMQRQQSLVDQKSEQPLNLSGDECQTRKRCYSESFAQEKPKSSTPNGEGSIIKDLLLKTKSQVQEEFTCSSCRISYTSCDNLEAHRRYYCKGSPKDFQLDLEKKEDLEKSDYYAIQPLPSPGPLLGNTRLVDAYAPPTKKVREVTTLRSLEELSKYPRPNSLQMFGGEVRILDNTGETKTMRIEPRQSNSPLSDHNPSKCATTETSSIVVRSGLHSGGTMVHKPPGTPSTTPSTSISIPNTPKILAPIIPNISTPNIAPTMSCYSYLEPHLNPLTSITAYNPLTLPQAGIAGILHGGKVIPYVPGMPGPHTLSSMEIPVTTGSSYKVIPGVPGLHMVPLDLASPVRTPSVPGIPGPASNSGMSVGPLDLASPRDPKTFKSPNGIISPKVPAKLEEKYKSRTGNLVNESTIEERSPKSVGKYNILEDSQVIDKEFGYSNGGESGHSFSDPPLNFDSQENGVVKMSSPEPFVPNGRTRSESTPVIVMNLDPPERFSDKSPDARQSPIEHQKPEGEQNPKFLRPSSLPLKPGTFTPKKHHGITPTANTLPLISPETPRPKKSYGQLYLNGQAYTYLGLKCSTKVIYCTLNHPQPMYVNQQHGLSMYSNWKICKESPPDMNLAHYDSRHRPSNYTVAWKKQEDILTHSSQRPTTPTSPDSGLESDTQEKTRRVKIFDGGFESNEDYTYVRGRGRGRYVCEECGIRCKKPSMLKKHIRTHTDVRPYTCKHCSFSFKTKGNLTKHMKSKAHYKKCVEMGVTPVPTSVCDENIDKEAIARLVAGGANEESTDEDEDSEGDESDESGSEEHEAAQSLLSLSQTSSKRLPGLLPSGRPTTYPYALNFPTTTVTSSIVSTTPVTSTVSVTSTTIIQSEVSNRYYFPSKKVAEEPRDSVIRSSKVDEDVEMEEVEVTRPMDLTTRTQSPRSRDILTPVCEPVLMQTIVQTMERLPPQGREWKPEAEGQMLQAYLKERHVMNSKMKLQFRVGTSKNDKKVVYSEEFGGSRGGYSGVTPLVTYTDPSRMQMEMRQEEEVKVEGRERRPFDIESLHLERDDTMKHEFGVGQGEIVQAVRVGLERFERNGRIERPPSQEFKLPSEIRAPEFKEGTSGENREFKAEHRLLIEGNKIDMPNCPRIELRDHGVNINELAKSIGEGMKHVVARKMVVGGPGFRSTSPNPGKPQAEFLQPSGGHGSNYGSVNEEGRSVCGFCNKVFNKPSHLRLHINIHYFERRFRCESCAVSFRTKGHLTKHERSVSHHNKVSMTSTFGAATESNPRPFKCEDCKIAFRIHGHLAKHLRSKMHIMKLECIGKLPFGTYAEMERSGVNLNDIDTTDCDNSLASLQILAYKLYEKDPSKMGQWDPEMGPPNIASGGETSSDEALVSTNDAKQISDVHVPNAHFDDNPLPYKCQMCPQSLRTVGDLQVHCYMEHSDRGKENTQSRINDEDQSRQNDDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-