Basic Information

Gene Symbol
-
Assembly
GCA_017141405.1
Location
JADHZF010000233.1:129409-131583[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00084 0.13 13.4 0.2 1 23 285 308 285 308 0.97
2 9 5.4e-06 0.00086 20.4 0.3 1 23 314 336 314 336 0.99
3 9 2.5e-06 0.0004 21.4 0.5 1 23 342 364 342 364 0.98
4 9 0.0053 0.84 10.9 3.0 1 23 370 392 370 392 0.99
5 9 3.3e-06 0.00053 21.0 0.3 1 20 398 417 398 418 0.95
6 9 0.0075 1.2 10.5 6.0 1 23 427 447 427 447 0.98
7 9 6.8e-07 0.00011 23.2 1.6 1 23 453 475 453 475 0.96
8 9 9.8e-05 0.016 16.4 1.4 1 23 481 503 481 503 0.98
9 9 6.8 1.1e+03 1.2 3.6 1 8 509 516 509 528 0.87

Sequence Information

Coding Sequence
ATGACAAATACTCAGGAAGCAGTGGATGCGCAAATCTCCGATGCTGATAATGTTCAGGAGGAAATTCAACTGACTGAGCTGCTACCAGTGCGGCAATCGAGAATCAATGATCGTGATAAGGATCAACACACAACTGACGGTCTCAAGGTGCTGAGAAGTTTCACAGAAGATGATAACCAATTTAATACGTTGAACTCGATGAGAAAACGACAGATTAGTGTGAGTTGTAAACAAGTTGATTATGTTGATGGCGAAGAGAATGATGGAAAGGCAAATAATCGCAAAACGCGAAAAGTTACAAACAAAGATTTTCCCAAAGATGAAGTGTACTATTTTTACCAAGAAAAACAAATAGAATCTGTTTCTGACGAAGTAACAAATCCCATGAGCAAATACCAGTGGAAGGTCTCAAGCAAGGAGTGCAGAATGGGCAAAAATATTCTAAAACGAGGAAATCAGGATATGAGGTTCCTGAGGATTCCTCTTCGAAAAGCACAAAGAGAATGGCATCTGGCGAAGATGAAGGAATCTGGTAGTGATGAAGTACAGAAATCTGGTGAGGAACGAGCAATGGAGAAAACCAAACCACTGTTATTAAAGAATAGTCGAAAATCTTGGAAAACACAGAAAACGGCTGAGAATGTCTGTGAAGATTCATCCTCTAAGGTTGAAGAAGAGAAGGGTTTGAGGATGAACATGAAAGTGATTCTCCAAGCGAGCAATATTCTGCAGCATGATAATGATAATTCAAGTGAAGACAATCAAAACCAATCAGATGCCCTTACGATCCAATCTATACAGACTGACCAAGTTGAGCCATCTTCACTGAAAGATTCTGAAAGCTTGAAAAAGTATAGCTGCGTAATTTGCGACGCCAAGTTCAAAGGGAATACGGGGTTGAGTACCCATTATAAAGTTGTGCATGGAACTGGACCATCATATAAATGTGATGACTGTGGCAAGGAATTCCCATTGAAAGAGCGGTTGAAGCTTCATGTCAGAATTCACACGGGCATCAAGCCATACAAATGCACAGACTGTGGAAAGGACTTTGCCAGAGGAGGTCAACTGAAGCAGCATCGAACTGTGCACAGCAAAGAAAAGCCTTATCAATGTAAGCTTTGTTTTGGTACATTCACCTGCTCTGGGAATCTCGCTCTCCACATGAAACGACACAAAGGCCAAAAAGACCATACGTGCAGCATCTGCGGAAAGGGATTCATCAGACGTGATGCTCTCAAGAAACATCTTGAATGTTTGCACAAAGATCTTAAAACGTTTCGCTGTACGATTTGCCATAAAACTTTCAAGGGCCACTTGCCGCAGCACATGAGAACGCATGCACATGATAAGCCTCATGCGTGCGCTACTTGTGGTCAAAAATTTGCCCAAAAATCACAATTGACTGTCCATCAGAGAACACACACTGGGCAAAGACCATTCAGGTGTCTTGTCTGCTGGCAGGCCTTTGCGCATTCGACTGCCCTGAAACTTCATACCAGAAGACACACCGGGGAAAGGCCCTTCAAGTGCCCGGACTGTAATAGAAAACATGATCTTGAGAATCATGTGATATTCTGTCATGGTGCCGACGACCTCGAGGGGACCGATAATAATGATGCTGATAAAGGTACGGATTCTGCGGCATATAAAAATATGAGTTTGGAGAGAATGCGATTACTGCTGGCCGCCCTACTGAAAAGAATTTCAACACCCGAGCGTCTCGATGAACTTGGCTTTGGTAAGAGGCTTATTGACGAAATTCTTCAGGATTCCTTGATCTCCGCTGGGAAAGAGCCTATCAAACATGGACGTTTTAGTGAGCTAGTGACACTGCAAAAAAACCTTAAGACATTCCTCGAATGGACTGTGCCCAAAGAACACTGGGACACATTCATGAAGATGAATAAATCTCCGGAGGAAATACTCGAAACACTCACTACGAGTTAG
Protein Sequence
MTNTQEAVDAQISDADNVQEEIQLTELLPVRQSRINDRDKDQHTTDGLKVLRSFTEDDNQFNTLNSMRKRQISVSCKQVDYVDGEENDGKANNRKTRKVTNKDFPKDEVYYFYQEKQIESVSDEVTNPMSKYQWKVSSKECRMGKNILKRGNQDMRFLRIPLRKAQREWHLAKMKESGSDEVQKSGEERAMEKTKPLLLKNSRKSWKTQKTAENVCEDSSSKVEEEKGLRMNMKVILQASNILQHDNDNSSEDNQNQSDALTIQSIQTDQVEPSSLKDSESLKKYSCVICDAKFKGNTGLSTHYKVVHGTGPSYKCDDCGKEFPLKERLKLHVRIHTGIKPYKCTDCGKDFARGGQLKQHRTVHSKEKPYQCKLCFGTFTCSGNLALHMKRHKGQKDHTCSICGKGFIRRDALKKHLECLHKDLKTFRCTICHKTFKGHLPQHMRTHAHDKPHACATCGQKFAQKSQLTVHQRTHTGQRPFRCLVCWQAFAHSTALKLHTRRHTGERPFKCPDCNRKHDLENHVIFCHGADDLEGTDNNDADKGTDSAAYKNMSLERMRLLLAALLKRISTPERLDELGFGKRLIDEILQDSLISAGKEPIKHGRFSELVTLQKNLKTFLEWTVPKEHWDTFMKMNKSPEEILETLTTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00168720;
90% Identity
-
80% Identity
-