Aver014187.1
Basic Information
- Insect
- Asbolus verrucosus
- Gene Symbol
- lola
- Assembly
- GCA_004193795.1
- Location
- QDEB01130526.1:14022-25236[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.00014 0.007 16.5 1.8 1 21 66 86 66 87 0.96 2 16 0.0026 0.13 12.5 2.4 1 23 95 119 95 119 0.92 3 16 0.074 3.8 7.9 3.9 1 21 166 186 166 187 0.92 4 16 0.013 0.66 10.3 2.9 1 23 195 218 195 218 0.96 5 16 1.3 65 4.0 0.2 1 17 243 259 243 259 0.91 6 16 0.00041 0.021 15.0 1.4 1 21 273 293 273 294 0.96 7 16 1.1e-05 0.00056 20.0 0.5 1 21 336 356 336 357 0.96 8 16 0.035 1.8 8.9 2.2 1 23 365 388 365 388 0.94 9 16 0.005 0.25 11.6 1.1 1 21 415 435 415 436 0.94 10 16 4.9e-06 0.00025 21.1 0.8 1 20 443 462 443 466 0.90 11 16 0.0094 0.48 10.7 1.2 1 21 510 530 510 531 0.92 12 16 4.1e-05 0.0021 18.2 0.9 1 23 540 562 540 563 0.96 13 16 0.0014 0.07 13.4 1.7 3 21 623 641 622 642 0.94 14 16 0.0027 0.14 12.4 2.3 1 23 650 673 650 673 0.98 15 16 2.2 1.1e+02 3.3 0.2 5 21 676 692 675 693 0.91 16 16 0.0012 0.059 13.6 1.6 1 23 701 726 701 726 0.96
Sequence Information
- Coding Sequence
- ATGAATATTAGAATGTGGGATCATCCCGCAATgacCTCGATACAGTTGCTCCAAGTGTTCACATTCGTACAAAAACAAAGGTTCACTCGCCAGACACTTAAAATGGGAATGTGGGATGGATTCACAGTTTCAGTGTCCTTATTGCAATTACGCGTGCAAACACAATTACCATTACATCAGGCATTTAaccGTCCATACCAGTGTCCGAAATGTCCAAACTCTTACAAACACAAGCGATCCCTCAGCAAGCATCTAAAATGGGAATGTGGAAAAGACCCACAATTCCAGTGTTCTTACTGTACTTACGCAtccaaatataaatatcattaTGTAACCCATATGGCTACTATCGCCCACACCAGTGTCCACAGTGAAGCACTTAAAGTGGGAATGTGGGAAAGCGCCGAAATTTCTCTGTTCTTACTGTGcttacaaatCGCGCTACGAGTGTCTAAGCTGTTCCCATTGTTACAAATATTCGAAACACaatgGCCGTTTAAATGCCCCAAATGTTTCCATGGATACAAACACAAGAGTTCTCTGAATTTCCATTTAAAGTGGGAATGTGGGATAGCATCACAATTTCATTGTTCTTATTGCATCTATTCGGCCAAGCAgaaaaataatcttattaGACATATGACTAAAGTGCACAAAATTCCCAAGACGGACATCAAGTTTAATtgtaaacACAAACACCCAACCTTTATAACAGAAAGTGGACGTCACGCATGCGGACGTTGCGGTTCACACTACAAGCGCAAAGCTGATCTCCGTTTCTTGCATAAGTCGATAAAAGAGAACGCTGCCGGGCTGTACGTTTGTCCGAATTGTAAAAAAACCTACAAGTTCAAATCGTCCGTTTATACCCACTTGAGGAACGATTGTGGAAAGGTACCAAGATACCATTGCGCCATCTGTAATTTCTACTGCAAATTTTACCATGTCTTGCAAAGACATTACCTGTCCAACACCCACCATTTCAATATGTTAGAGGCTGGTTCGTTTGTCTGTGATAATTGCGGACGAGCATATAAACGAAAGAGTTCACTCTATAACCACAGGAGATGGGAGTGTGGGAAAGAACCACAGTTTAAGTGTTCTTATTGCCCTTACAAGGGCAaacagaaaattcattttgttatgCATGTCATGGCGAAGCACAAGGAACACAAACACGAAGTGCTCAGCTCCTCGTACAATAAatattttaggAAAAGGAAAGGTGGTTATGAAACACCGTTTCCGTGTCTGATTTGTGGCCGCCAATATAAGTACAAGTCGAACATGACCTTCCACATGAAAAAATGCGGCAAAGACAAGAGGTTTCAATGCGAGATTTGTGAAAAGAAGTTCACCTCAAAGTACGCTTTACAGAGGCATAATATTGACGACCATTCGCATGTGAATGCGGTCGAAGTTACAAACACCAAAGGAATCTCTTGCAACATAAACGATTTGATTGCGGGAAAGAACCGAGTGTTATCGGATCAGCAAGTAAGGCCCGGCTACAGTAATGAATCGCTTTTCGCTTGTCGACACTGCGGCAAAAGATATCGATGGAAGTCGACGATGAGAAGACACGAACAGGTCGAATGTGGGGGAAAAGAGCCGATGTTTCAGTGTCCGCAGTGTCCTTACAGAGCGAAACAAAAGGGCAATCTCGGGGTCCACATCAGGAAGCATCATCCGCAGCTGATGATGATCAACGATTCCATCGTCCAAAAGGCTGACaatttcctTACAAATGTGGCAACTGTGGCAAACGCTACAAACACAGTCCGTCCCTGTACAAACACTGCAAATACCAATGTGGCAAAGACGCCCAgtttgtttTTTTCTTTTGTAGAAAAATCGAGAGCTTTTTGTCcaaattgtaacaaaagtttcaaaaacatgaaaaccaTGAAGTACCATATGAGTAGAGACTGCGGCAGCCTTAAATCTTACGTCTGTGATATTTGCATGTACGCCTGCAAGCGGAAATTTGCTCTGGATAGACATATCAGAAGACGACATCTTGAAAATTGCCCAAGAGTGTACAGCCATTACACTTCCAGAAGTCGCCATCTTAAGTACGAGTGCGGGAAGTCCCCAACTTTCGAGTGTAACATCAACTTTTGCCCATACGTGGCTAAGAGGAAGGGCCACTTGAAAACACACATGATCAGAAAACATAACGTTACCTTGTAA
- Protein Sequence
- MNIRMWDHPAMTSIQLLQVFTFVQKQRFTRQTLKMGMWDGFTVSVSLLQLRVQTQLPLHQAFNRPYQCPKCPNSYKHKRSLSKHLKWECGKDPQFQCSYCTYASKYKYHYVTHMATIAHTSVHSEALKVGMWESAEISLFLLCLQIALRVSKLFPLLQIFETQWPFKCPKCFHGYKHKSSLNFHLKWECGIASQFHCSYCIYSAKQKNNLIRHMTKVHKIPKTDIKFNCKHKHPTFITESGRHACGRCGSHYKRKADLRFLHKSIKENAAGLYVCPNCKKTYKFKSSVYTHLRNDCGKVPRYHCAICNFYCKFYHVLQRHYLSNTHHFNMLEAGSFVCDNCGRAYKRKSSLYNHRRWECGKEPQFKCSYCPYKGKQKIHFVMHVMAKHKEHKHEVLSSSYNKYFRKRKGGYETPFPCLICGRQYKYKSNMTFHMKKCGKDKRFQCEICEKKFTSKYALQRHNIDDHSHVNAVEVTNTKGISCNINDLIAGKNRVLSDQQVRPGYSNESLFACRHCGKRYRWKSTMRRHEQVECGGKEPMFQCPQCPYRAKQKGNLGVHIRKHHPQLMMINDSIVQKADNFLTNVATVANATNTVRPCTNTANTNVAKTPSLFFSFVEKSRAFCPNCNKSFKNMKTMKYHMSRDCGSLKSYVCDICMYACKRKFALDRHIRRRHLENCPRVYSHYTSRSRHLKYECGKSPTFECNINFCPYVAKRKGHLKTHMIRKHNVTL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -