Aver007700.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Asbolus verrucosus
Gene Symbol
topi
Assembly
GCA_004193795.1
Location
QDEB01071468.1:16718-20395[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 6.1e-06 0.00031 20.8 0.6 2 23 123 145 123 145 0.97
2 16 2.6e-05 0.0013 18.8 1.0 2 23 182 203 181 203 0.97
3 16 8.7e-05 0.0044 17.1 0.5 3 23 229 249 228 249 0.97
4 16 7.3e-06 0.00037 20.5 0.6 2 23 279 300 278 300 0.95
5 16 0.011 0.58 10.5 0.6 1 23 323 346 323 346 0.96
6 16 0.0022 0.11 12.8 1.8 2 23 360 381 359 381 0.97
7 16 0.00072 0.036 14.3 8.4 1 21 416 436 416 438 0.95
8 16 0.013 0.68 10.3 1.4 3 23 460 481 460 481 0.92
9 16 9.2e-05 0.0046 17.1 1.6 1 23 506 528 506 528 0.98
10 16 0.016 0.8 10.0 0.5 2 23 544 566 543 566 0.94
11 16 4.6e-06 0.00023 21.2 0.2 1 23 581 603 581 603 0.94
12 16 0.039 2 8.8 0.0 1 23 635 658 635 658 0.95
13 16 0.0014 0.069 13.4 1.5 2 23 669 690 669 690 0.97
14 16 0.0013 0.065 13.5 0.2 1 23 701 724 701 724 0.96
15 16 3.4e-06 0.00017 21.6 1.5 1 23 732 754 732 754 0.99
16 16 0.00023 0.012 15.8 0.2 1 23 767 790 767 790 0.94

Sequence Information

Coding Sequence
ATGGCCGATGATAAACTTTCGACTATGGTTTGTCACCAGtgcattgaaaaaattaataactggCAGTCCTTCAAACATAGTTGTTCCGAAAACCAGACCAAACTGGAACAGTGGATGAACATGTCTAATTCTGATTTATCAGATATGAATATCCAGATCAAAGAAGAACCAGTTGATCATGAAGTACTGTCACCAGAGGTCATAATTAATGGCGAAGgttcaatgaaaaatgaacCGATGGAAGAAGAGTACAGTGATTTGCCACCTCCTCTAACGCCACAAGGTCCAGAAGATGGGGATGTGGAAATTGTAGTTCACTCTCCATCGTCCCAGCTTAATAATAATGATGATGAAGATAATCCCCGGAAATGTGGTTTTTGTGGAAAAGTATTTAGTTCTGCGGGAAATCGCAAGAAACATCAAAGAGTCATACATGGGATAAAAAGTTATGGTTCCACTACCGAATCTGATGTTGAACCAGAAGATGAAGAAGGAAATGGCAAAGTTATCAATCCGATGTTCATGCAGAAACTTCCGGGGACGACTTGCCCAGTTTGTTCAAAAGAATATTCATCAAATAACAACATGTGGCGACATTacaaaacacattttgaagAAGATTGTGGAGGTATGTTTAGTACGTCCGAATGGGAAAAACATAAAGGGatgcataaaaaaaagaattgcaaCGAATGTGGAAAAGTTTTCCAGTTCCAATCAGAATTGGATCAACATAGAAGTGTGCACTTGAATCTCAAATTGTACAGAGATTCGAAAACACAGTCTTATAAAAGTACAATGGTTAGTCCAAATAGTGAAAGCAACATCGTTTTGATGTGTGAAATTTGTGATAGAATGTTTACATCGAAAGACCAGCTCAAAGAACATAAAGTGACACACGAAAAAATGCCAGTTTTGGAATCGGCTGAAGTCGGTGTGGTCGAGGAAGATAATAAATCGAAGAAATTTGCTTGTAAACTGTGCAACAAGCAATACTCTGGTTATGGAGGTTTATGGGATCACAATAGGAAAAAGCATCCAGATAATAAATCTCCTCACAGCGCAGATTTTCCAAAGCAATGTAAATATTGCGATAAAGTTTTCTTTACTGGTGGTTCTTACTTTATGCACAAACAAATGCATGAGAGGAACAATCAAATCCCCTTAAAGAAACAAGCAGAGGTTTCTCAAAACAAACCTCAATCTACAGAAGAAGAAGCCAACGAAGACGATACTGAGTCTTATCATACTTGCAAACGTTGCTTTAAAGTCTTTTCGAACAGATACAATCTCAAAACTCACATGAAATGCCATggaattgtttataatatgaGTCCAACGACCAAGAGTACCAAAAAGGGTTCAAAGAAAGTCTGGTGTGATATTTGTCACTgtgcttttgaaaatttagcaaGTCTTGAAAAACATAAAGCCGAAGGTCATGCCGAAACTGACGAAGGAATGCCGACGTTATCAGATGAACAGAGCGAGGGTGATCTTAAAGCACCTTTCGTTTTTACCTGTGATGTTTGCGTACAAACTTTCACCACTAAGATGGCTTTAAAGAAACATAAAGAGAGACATGCGCGCGAAGTGAgacctataattaaaaataaacagactTTAGTCTATTGCAAGTActgcaaaatttcttttgcaaaTACCCAGATATTATCCAATCATATGAAAGAGGAACATTTGGAACAATATAAAGCTAGAGGTAAAGAGAGGAGTAAACAGTTCATCTGTAAGATTTGTGGGAAAACTTTCACTTCAATGTCAGCATTATACGCTCACCAAGGTTGGCACAAACGTGGTAAATTCGAGGCCCCAGTCAGAACAGAACAACCCTTACTTAAAGTAGTTAAGGAGGAACCAAAAGCAAAGGTAGAAGCTGCACAGTTTCAGTGTTCCACCTGCAATGCCGTTTTACCAAATGATACAGCTTTGCAAATTCATATTCTCGAAAAACACAGAAATGTCAATGCTACTGTTTTACCAGCACGTTGTACAATGTGTAATTTAGATTTCAGTTCACAAGATGAGTATGAACAACATAAAAGGTTTCATGCCATGGTTGATAAACAACCTAAAAAGACTTTCCCATGCAACTATTGTCCAGCTGCTTTTGGTAAAGTTGAGATGTTAAAAACCCATCTCAGACAATTTCATCGAGAACAAACTCAACAAGAGTATAAATGCCCACAATGTGAtcgtgtttttgaaaaacacagTTCTCTTAGTATTCATCTGAAAGTTcatgaaaaacaaagattGACAACTGGGGCTAAACCGTTGTATTCATGCTCAATTTGCAATAAGGGATTTGATCTGCCGAAGGATCTGAGAACTCATACAATACAAGCACATCCTTTCTGA
Protein Sequence
MADDKLSTMVCHQCIEKINNWQSFKHSCSENQTKLEQWMNMSNSDLSDMNIQIKEEPVDHEVLSPEVIINGEGSMKNEPMEEEYSDLPPPLTPQGPEDGDVEIVVHSPSSQLNNNDDEDNPRKCGFCGKVFSSAGNRKKHQRVIHGIKSYGSTTESDVEPEDEEGNGKVINPMFMQKLPGTTCPVCSKEYSSNNNMWRHYKTHFEEDCGGMFSTSEWEKHKGMHKKKNCNECGKVFQFQSELDQHRSVHLNLKLYRDSKTQSYKSTMVSPNSESNIVLMCEICDRMFTSKDQLKEHKVTHEKMPVLESAEVGVVEEDNKSKKFACKLCNKQYSGYGGLWDHNRKKHPDNKSPHSADFPKQCKYCDKVFFTGGSYFMHKQMHERNNQIPLKKQAEVSQNKPQSTEEEANEDDTESYHTCKRCFKVFSNRYNLKTHMKCHGIVYNMSPTTKSTKKGSKKVWCDICHCAFENLASLEKHKAEGHAETDEGMPTLSDEQSEGDLKAPFVFTCDVCVQTFTTKMALKKHKERHAREVRPIIKNKQTLVYCKYCKISFANTQILSNHMKEEHLEQYKARGKERSKQFICKICGKTFTSMSALYAHQGWHKRGKFEAPVRTEQPLLKVVKEEPKAKVEAAQFQCSTCNAVLPNDTALQIHILEKHRNVNATVLPARCTMCNLDFSSQDEYEQHKRFHAMVDKQPKKTFPCNYCPAAFGKVEMLKTHLRQFHREQTQQEYKCPQCDRVFEKHSSLSIHLKVHEKQRLTTGAKPLYSCSICNKGFDLPKDLRTHTIQAHPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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