Basic Information

Gene Symbol
wdn
Assembly
GCA_029963805.1
Location
JAPWTK010000051.1:617839-630751[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00025 0.019 16.2 0.2 1 23 333 355 333 355 0.95
2 12 1.3e-05 0.00099 20.2 1.5 1 23 363 385 363 385 0.99
3 12 0.00022 0.017 16.3 0.4 2 23 393 414 392 414 0.97
4 12 6.2e-06 0.00047 21.2 1.0 1 23 420 442 420 442 0.98
5 12 1.1e-05 0.00083 20.5 1.2 1 23 449 471 449 471 0.99
6 12 0.0026 0.2 13.0 0.9 3 23 479 499 477 499 0.96
7 12 2e-05 0.0015 19.6 0.1 1 23 505 527 505 527 0.98
8 12 1.2e-06 9.1e-05 23.5 1.2 1 23 533 556 533 556 0.96
9 12 2.1e-05 0.0016 19.5 0.5 1 23 562 585 562 585 0.95
10 12 8.4e-06 0.00065 20.8 2.1 1 23 591 613 591 613 0.99
11 12 0.00018 0.014 16.6 0.4 1 23 619 641 619 641 0.94
12 12 0.0048 0.37 12.1 0.1 1 21 647 667 647 671 0.92

Sequence Information

Coding Sequence
ATGTCCACGAGCACAAACTCGTGCTTGGCCTGTAAGGTTAATTGCTTGTCCGACGACGATGCCGTGGTGATTTTCAGCAAAGAGGGCGACTCGGAAGGATACGAACATGTCGCCTCGCTACTGACGAAGATACTGAACAAGGCTATAAAGCAGGAGCCGGATCGGGCCCAGGTAGTGTGCAGAAAGTGCTACGGCCTCCTGCAGGAGCTCGACGAGCTCCAGAACAGGGCAGCGGAGATAACGAACGAGCTGCTCGGCAGTCACGGGGACGGCATCGGAAAATCGGAAATAGAGGACGAGACGGAGGTGAAGGAGGCTAAAGGGATAGGGGAATCTGACAAGGAGAACGAGGTGCCCAAGAAAATCCTGGACATACCGTCTTCCGATGAGGACTCCGCTCAGGTGGACAAGACGGCCCTCCAGTCCATCGAGGACATCGAAATGGAACTGGTCAAGATGCACGGTGGGGTGGGGCCGGACGATAAGGAGGTGAAGGAGCAGGAGGAGCTCGAGAACGCGGAGATGGAGGTCGAGGAGGAGCACCAGGAGTTCGGCGGCGACATCATAGACTCGGGGGCCATAGAGCACTCGTCCGATTCGGATTACGAGCCGCCCGCTGATATGGTCGACCGTTCCAACGATCTCCTCCTTCAGGCCGCCGCCGTTGCAGGAAAGGAATATCAGAATGTCAAGGTGAAGGTGGAGCCGGGCGGCGAGGAGGCCGTGCCCGCCGGCGCCGAGCGCCCCAACATCCTCAAGAAGAAGACGCCAGCGGGCGGGGAGCGTCCGGTCCGCGTGGCCGTCGCCGCCGCGTCGGCCGCTCGCCCCGTCGGCGCCGCCGCCGACGCCAAGAAGGCGGAGGAGTTCTTCGCGTTGCCGGTGGTGTCGCGAGAGGGCAACCTCTACACGTGCCTGCTGTGCCAGGGCGACGAGACCGTCGCCGGCGAGGCCAAGGCCATCGCGATGCACGCCAAGCAGGCGCACGGCGTCCGCGTCTACATCTGCGACGTGTGCGGCCAGGACTTCCGCAAGCGCAACCAGCTGTCGGCGCACCTCGACGAGCACGTCGCCGCCGAGGAGGGCGACTTCCAGTGCGAGATATGCAACAGGATATTCAGCAACCTGCGCCTCTTCCGCATACACAGGCGCATGCACTACCCGCAGAACAAGGCCTGGGAGTGCGGCACGTGCGGCAAGAAGTACAGCAGCAAGAACTTGCTCGACGAGCACACGAACACGCACCTGGGCGTCAGGCCGTACATGTGCAACGTGTGCGGCAAGGACTTCGCCAGCAAGTACACGTACAAGGCGCACGAGAAGACGCACGAGGTGCGGCCGCGCCCGTTCCGGTGCCCGCAGTGCCCCAAGTCCTTCCTCAGCCAGCAGAACCTGACGCAGCACGAGCGCACCCACTCGGGCGCCAAGGAGTTCGGCTGCCACCTGTGCGGCAAGCTGTTCGGCTCCGCGCACAACCTCGAGGTGCACTCGATCGTGCACACCGGCTACAAACCGTTCGTGTGCGGCCTGTGCGGCAAGGCGTTCGCCAGGAAGGCGGAGATCAGGGACCACGAGCGCACGCACACCGGCGAGAGGCCGTACCAGTGCGAGTTCTGCGGCGCCACCTTCAGCCAGAGGTCGAACCTGCAATCGCACAAGCGGGCCACCCACTACGACGACAAGCGCTACCAGTGCTCCGACTGCGGCAAGGGCTTCAAACGGCGCCGGCTGCTCGACTACCACGTGAAGGCGGCCCACACCGGCGAGAGACCGTTCAAATGCGACGTGTGCGACGCCACCTTCGTCTACCCGGAGCACTTCAAGAAGCACCGCCGGATACACACCGGGGAGAAGCCATTCCTGTGCGAGGTGTGCGGAAAGGCGTTCAACAGCCGTGACAACCGCAACGCGCACCGCTTCGTCCACTCGGACAAGAAGCCTTACGAGTGCCTGGTGTGCGGCGCCGGCTTCATGCGCAAGCCGCTGCTCTACCAGCACATGCAGGCGCAGGGCCACCTCAACGACACCATCGTCGTGAACCAGCCGCGTCTCACCACCGACGACGACCAGCTGGTCACCGTGAACTCGGCGGGCGAGATGGAGATCGTGGACgcggccgccgccgccgccgccgactCCAAGCTCTACATCCAGGACCAGGACGGCACCGAGCACATCATCATCGACGGGCAGCAGATCAGCTTCGCGGAGGCGACGGCCAGCGACGAGGAGGAGAACGAGGGCGAGATCATCGACGAGATCGAGCAGGTGGTGACGGGTCAGGTGGACGAGGACTACGAGGAGATCATCACCAGCGACGCGCTGGCGCACGGCGAGACGCAGATCATCGAGACGCCCGAGGGCCCCGTCCAGCTGGTGAAGGTTCGCATCCCGAACGAGAACGGCGAGGAGGAGGAGGCTTGGATCAAGATCGTGCCCGAATGA
Protein Sequence
MSTSTNSCLACKVNCLSDDDAVVIFSKEGDSEGYEHVASLLTKILNKAIKQEPDRAQVVCRKCYGLLQELDELQNRAAEITNELLGSHGDGIGKSEIEDETEVKEAKGIGESDKENEVPKKILDIPSSDEDSAQVDKTALQSIEDIEMELVKMHGGVGPDDKEVKEQEELENAEMEVEEEHQEFGGDIIDSGAIEHSSDSDYEPPADMVDRSNDLLLQAAAVAGKEYQNVKVKVEPGGEEAVPAGAERPNILKKKTPAGGERPVRVAVAAASAARPVGAAADAKKAEEFFALPVVSREGNLYTCLLCQGDETVAGEAKAIAMHAKQAHGVRVYICDVCGQDFRKRNQLSAHLDEHVAAEEGDFQCEICNRIFSNLRLFRIHRRMHYPQNKAWECGTCGKKYSSKNLLDEHTNTHLGVRPYMCNVCGKDFASKYTYKAHEKTHEVRPRPFRCPQCPKSFLSQQNLTQHERTHSGAKEFGCHLCGKLFGSAHNLEVHSIVHTGYKPFVCGLCGKAFARKAEIRDHERTHTGERPYQCEFCGATFSQRSNLQSHKRATHYDDKRYQCSDCGKGFKRRRLLDYHVKAAHTGERPFKCDVCDATFVYPEHFKKHRRIHTGEKPFLCEVCGKAFNSRDNRNAHRFVHSDKKPYECLVCGAGFMRKPLLYQHMQAQGHLNDTIVVNQPRLTTDDDQLVTVNSAGEMEIVDAAAAAAADSKLYIQDQDGTEHIIIDGQQISFAEATASDEEENEGEIIDEIEQVVTGQVDEDYEEIITSDALAHGETQIIETPEGPVQLVKVRIPNENGEEEEAWIKIVPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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