Basic Information

Gene Symbol
-
Assembly
GCA_029963805.1
Location
JAPWTK010000007.1:1332313-1341450[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0029 0.22 12.8 2.9 2 23 149 170 148 170 0.97
2 16 0.01 0.77 11.1 4.6 3 23 178 198 177 198 0.97
3 16 6.6e-06 0.00051 21.1 2.2 1 23 205 227 205 227 0.96
4 16 0.00044 0.034 15.4 0.9 1 23 325 347 325 347 0.99
5 16 1.9e-07 1.5e-05 26.0 4.4 3 23 355 375 354 375 0.98
6 16 0.00037 0.028 15.6 3.0 2 23 399 421 398 421 0.96
7 16 2.3e-05 0.0018 19.4 3.4 2 23 504 525 503 525 0.96
8 16 0.00016 0.013 16.7 1.5 1 23 531 554 531 554 0.93
9 16 2.2e-06 0.00017 22.7 0.9 1 23 559 581 559 581 0.98
10 16 1.4e-06 0.00011 23.3 2.4 2 23 592 613 591 613 0.97
11 16 3.2e-07 2.4e-05 25.3 0.9 1 23 620 642 620 642 0.97
12 16 3.6e-05 0.0028 18.8 1.6 3 23 654 674 652 674 0.92
13 16 0.00012 0.0092 17.2 4.4 1 23 680 702 680 702 0.99
14 16 5e-05 0.0039 18.4 1.7 1 23 708 730 708 730 0.96
15 16 1.1e-07 8.5e-06 26.7 0.4 1 23 736 758 736 758 0.99
16 16 0.00017 0.013 16.7 0.1 1 23 764 788 764 788 0.93

Sequence Information

Coding Sequence
ATGATTAATAAAGAATTAGGGCTGATCATCGATAAGATCTGTCGCTGCTGCATGTGCGAAAATGATAATATGCACAATATGTTCGAAAATAAAGAGGCTACTGTGAGCTCCTCCTCTGTACTACTCTCGGAGATGTTCACTGCTTGTGCCTCAGTGGAGgtcGCGTTTGGAGACGGGCTGCCCTACAACCTGTGCGACGCCTGCGAAATTAAGCTCCAAAACGCGTACGAATTCAGACAGCAATGCCAAAAATCCGACTCCGCACTCAGGGAATTAACCACAGCCGAAACGAAAGCAAACATTAACATAGCGAAGGAAGAGAACATCGTCATCCAACCCGATGTGCTCGACGACATGTTCGACGAGGAGGACGAGGTGCCCCTACTGAAACGCGCGCTAAAAAGGAAACGCGGCAGACCAAAGAAAACCGACATCAACAACTTGTCGTGCACCTTCTGCAACAAGGTGTTGCACACCAAGAAGGGCCTGCGGGTACACCTGAGGTCCCACACGGGGGAGAAACTGAGGCACTGCCTGTTCTGCGACGCCAAGTACACCCGCACCAACCACCTGATCCGACACATAAACACGCACGACAAGCCGGGGCTGACGCACCCGTGCGAGCATTGCGACAGGACGTTCACCAGGGCCGCCGAGCTGTTCAAACACGCCAGGGAGCACGACAAGGACGAGTCCCCCGAGAAGGACATCAAACAGGAGAAGGAAGACGAGGAGATGAAGCCCGAGCTGCCCCCTTCAGGCGAGAACATCATGGTGGTCGTGGAGAGCAACGCGGTGGACGGCTTCAACGACGACGATAACTTGGATAACGACAATTTCAACGACTTTCCGTTCAGCGACAATGACGACGACCACGGAGATAGCGAAGACGATTTCCTCGTTCACGTCAAGAAGGAGAAGAAGGGCAAAAAGAAGAAGGGGGAGGAGGAAGGGGACAAGGATAAGATCCTCTACGAGTGCAAGGAGTGCTCGAAAATGATGACGACCTATATCGGACTGAAGATTCACATGAGGAGGCACACAGGGGCCGATCTGTCATTCTGCGACATGTGTAACAAGTCTTTTACGAAACCGAGCCACCTGAATAGGCATATGCGAACGCATGGCATCATGGACGCCAAAGAGGTGAGGCCCATAAGGCAGAGTTCCGACGCCAAAGGAAAAAGGGTCATGGAGTGCGACTTCTGCGACCGTAAGTTCAAGTACAAGAAGAGCTTCGTGCATCACATGCAGGTGGAGCACGGGATGTCCGACGTGGAGAGCGATTTCGGACTCACCGACGACGGAATGCCCCTGATTAACATTGGAAGCGGTTCCGGCCAGGCCAAAACCCAGAACGAAGGTGGCGCCGAGGAGCACATGGAGGAGTCGGAGGACCGAAAGCCCGTCATTCCCTCGGACGCTGCcaaggaggaggaggaggacaTCGCGGGCCTGCCGGAGGCGGAGAACCTGCTGGTGGTGAAGCGGGTGCGCAGCAAGAACCAGGTGTGCCACGTGTGCGGCGTCAGCTTCTCCAGGACCAACCACCTGACGAGGCACATGACGCTGCACCGCTCCGTGCTGGTGCACCAGTGCGACAGGTGCGAGAAGGCCTTCGCCACCGAGGAGCACCTCAGGAAGCACGTGGAGGAGGACCACATCAACAAGCCGTACGTTTGCACCGTGTGCAACAAGCCGTTCACGAGGGGCGAGCACCTCATACGCCACCTCAAGGTGCACCAGGCAGGCACGGAGAAGGAGGCCAGCCTCAAGTGCTCCATATGCGACACGACGTTCACCAGATCGGATCACCTGGCGCGCCACACGAAGATCCACCTGCTGCAGGACAAGCGCCACGTGTGCGTCGAGTGCGGCAAGGCGTTCAACAGGCTGGACAACCTGAAGACCCACCAGCGCATCCACACCGGCGTCAAGGACACCTCCAAGCTGCACCTGTGCATCTACTGCGGGAAGGAGTTCAATAATTCGAGTAACATGATCGTGCACATGCGCAGGCACACGGGCGAGCGGCCTTATAAGTGCAGCGAGTGCGGCAAAGGGTTCCCGAGATCGCACGATCTCAAGTGCCACGAGAGGACGCACTCCGGCGAGAAACCGTACCTCTGCACCCTGTGCGGGAAGTCGTTCAACAAGAGCAACAAGTTGCTGCGCCACAGCCGCGTACACACCGGCGAGAGGCCCTACGTGTGCAACATCTGCGGCCGGGCGTTCACCCAGTCGAACGACCTCTCGCTGCACATGCGCCGGCACACGGGGGCGCGGCCCTACGCGTGCGGCGTCTGCCCCGCTCGCTTCATCCAGTCCGGCCAGCTGAAGACGCACCGCAGGACCACCGGCCACTGGATGGAGACGCAGCCCGACCTCAAGGGCGGCCATCGGGTGGAGCCCGTCACGCCGGCCCATGAGCCGATGCCCATCAGGTTCAAGTCGCACGGCAAGTTCAAGAAGGAGCAGGAGCCCGTCGAGGAGATGCAGGCGATGGCGGACGCGGCCGGCGCGCAGCAGATGGTCGAGGAACATGCCGGGGACGAGGCGGGACAGGCGCAGACCCAGCCTCAGCGCATCCTCATGGGCATCATGGGCAACATCAAGATCCAGAACGAGATGCAGCCGTTGATCATCGAGAGCACGAAGCTGGTGGAGTTGCACAACGCGGGGCTGGTCAACCTGCCGTCGGTCATCCAGACGACGAATGGTGACGAGATCAAGCTGAAGTCGGAGGACGAGGCCGTCGTGTTCTCCAGCGTGGGGCACACCAGCACGACGTACACGACCAGCGAGAACTTCAACTTTCAGAGTTTCCAGTGA
Protein Sequence
MINKELGLIIDKICRCCMCENDNMHNMFENKEATVSSSSVLLSEMFTACASVEVAFGDGLPYNLCDACEIKLQNAYEFRQQCQKSDSALRELTTAETKANINIAKEENIVIQPDVLDDMFDEEDEVPLLKRALKRKRGRPKKTDINNLSCTFCNKVLHTKKGLRVHLRSHTGEKLRHCLFCDAKYTRTNHLIRHINTHDKPGLTHPCEHCDRTFTRAAELFKHAREHDKDESPEKDIKQEKEDEEMKPELPPSGENIMVVVESNAVDGFNDDDNLDNDNFNDFPFSDNDDDHGDSEDDFLVHVKKEKKGKKKKGEEEGDKDKILYECKECSKMMTTYIGLKIHMRRHTGADLSFCDMCNKSFTKPSHLNRHMRTHGIMDAKEVRPIRQSSDAKGKRVMECDFCDRKFKYKKSFVHHMQVEHGMSDVESDFGLTDDGMPLINIGSGSGQAKTQNEGGAEEHMEESEDRKPVIPSDAAKEEEEDIAGLPEAENLLVVKRVRSKNQVCHVCGVSFSRTNHLTRHMTLHRSVLVHQCDRCEKAFATEEHLRKHVEEDHINKPYVCTVCNKPFTRGEHLIRHLKVHQAGTEKEASLKCSICDTTFTRSDHLARHTKIHLLQDKRHVCVECGKAFNRLDNLKTHQRIHTGVKDTSKLHLCIYCGKEFNNSSNMIVHMRRHTGERPYKCSECGKGFPRSHDLKCHERTHSGEKPYLCTLCGKSFNKSNKLLRHSRVHTGERPYVCNICGRAFTQSNDLSLHMRRHTGARPYACGVCPARFIQSGQLKTHRRTTGHWMETQPDLKGGHRVEPVTPAHEPMPIRFKSHGKFKKEQEPVEEMQAMADAAGAQQMVEEHAGDEAGQAQTQPQRILMGIMGNIKIQNEMQPLIIESTKLVELHNAGLVNLPSVIQTTNGDEIKLKSEDEAVVFSSVGHTSTTYTTSENFNFQSFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-