Basic Information

Insect: Arma custos
Gene Symbol: hb
Assembly: GCA_037127475.1
Location: CM073760.1:44889908-44904127[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00095 0.21 14.1 1.3 2 23 220 241 219 241 0.97

2 6 0.0063 1.4 11.6 0.7 2 23 244 266 243 266 0.96

3 6 0.065 14 8.4 1.0 1 23 293 315 293 315 0.98

4 6 0.0033 0.71 12.4 3.1 2 23 323 344 322 344 0.97

5 6 0.00015 0.033 16.7 4.5 1 23 350 372 350 372 0.99

6 6 0.063 14 8.4 5.1 1 23 378 402 378 402 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00095	0.21	14.1	1.3	2	23	220	241	219	241	0.97
2	6	0.0063	1.4	11.6	0.7	2	23	244	266	243	266	0.96
3	6	0.065	14	8.4	1.0	1	23	293	315	293	315	0.98
4	6	0.0033	0.71	12.4	3.1	2	23	323	344	322	344	0.97
5	6	0.00015	0.033	16.7	4.5	1	23	350	372	350	372	0.99
6	6	0.063	14	8.4	5.1	1	23	378	402	378	402	0.93

Sequence Information

Coding Sequence: ATGGACCCGTGGATCCGCGAGCTAAGGGTTGAATGGAGGGGAGGGGGCGGGGAAGCAGGAGTGGGGATAGGGAGGGGGTGTGAGGTAGGTCCGGGAGGTCGGGGTTCACCCTTAGTTCCTCCTCGCCCTTCGTTCCATTCGGTGGGAAGAGTCCAGTTCAGGATACCTATCACTCCATCACTTCACTCCACAGCTGAGGTCGTGTTTCTTGTTTCAACGGGTGTATGttgGAATGAGATGATTGTAACTCCTGATATATACTTCAACAACCCGAGGATGAACATCGGTGTGCAGTATGACCCCCGACACTCCATCTTCCCCAACATGGACCACCATCCATGGATGTCGTCCCCGACTCCACAAACTTCTCCGGCCCCAGTCATCaaagagGAGCCTCGCGACGATGCTGAGTACGGACAGAGCAGCCAGGACAGCGCGCTGCCCCTGACGCCGCCCCCGTTCCAGGGCTACCCCCCGGCGAACGCCTACCGCGCCGCCACGCCTCCAAAGGACACGCCTCCGGCCTCCACCCCATCGCCCAGGGAAAAGGGAGAGGGCAGCTCCAACTCGGAAGGAGAGTACTACGAGAGCGGAGAATCCCTTAAGAGGCTCCAGATGGCCCTTCACAGGAACGGCATGATAGCCGAGGAGAAGCTACAATGCCCGGTCTGCGAGTTCTCTTGCAGCGTCAGgtcACAGTTTAATGAACACCTGATGTCGCATGAAACTAAATGTTCTATGTGTGATTTTAATGGAGAAACCAGTGAGAAGTTGAGAGAACACATGAGGAATGTCCATGATTGTGATGATGACAGCAGCTGGGGTGATGATGAGCTCAACACTCCCAAAGTTAATTCTcaaggaaaagtaaaaacttttcGTTGCAAACAATGTGAATTTTCAGCTGTCACGAAATTAGAATTCTGGGAGCATTCACGTACCCACATCAAACAAGAGCGTCTTCTCACTTGTCCTAAATGTCCATTTGTGACCGAGTACAAACACCATCTGGAATATCATTTGAGGAATCATTTTGGATCGAAACCATTTAAATGTGACAAATGCTCCTACTCCTGTGTAAACAAGTCCATGCTTAATTCTCACTTGAAAAGCCACAGTAACATTTACCAGTTTAGATGTGCTGATTGTACTTATGCTACCAAATATTGTCACAGTTTGAAACTGCATTTGAGAAAATACGCCCACAGCCCAGCCATGGTGCTAAATCCGGATGGTTCTCCAAACCCTTTACCAATTGTTGATGTGTACGGTACTAGACGTGGCCCGAAGCAGAAACCTAAGCAAGATCAACAACCACTGCAACCTCAAGTTGCAAATATCTTCAACCCATATTCCTTGCTTCCAACACAGATgccatattataatattctcAATGGATTTGGAGGATTCCCGTTCCCTCAAGATCTAAACTTAGTAGAGAAGAATAACAATGTTGAAAAAGCAGAAGTTAAAGAAGACAAAGCTCCTCTCGATTTGAGCTGTCCTGAGCCAACAGTTGAAGAAAGCAGTCCCGAAGCTCCACcaagaaaaaggagaaaaggTAAAGCTTTCAAACTTGACACAATCGCTCTTCGCCTTCAGCAGCAAGTCGAGGTGGAGGAGCAGCAGCCAGAGCCTACTACACCACAGCACACTTCACCTCCACCACAGCCCACTTTCACTCCGCCACAGCCCACTCTAACTCCACCACAGCCAACTCTGACTCCACCACCTGAGTTGCCACAGCCAACACCGACTGCACCACCTGAGTTGCCACAACCCACTCCGACTCCACCACCTGAGGTTGCAGAGCCAGAGCCAAAATCTCCAAAGATCGAGTCCTGCGAAGCTGACAGTGAACAGAAACCGGAGAAGGAAGAAGTACATACACACACATGTCACGGCTCCTCGCGCAGTCATGCTGGAATAAGCCTCACAGCTGGATTCTGCGATGGGCAATTATCATGGCGAGATAGGAGTCCACATGGAGGAATAATGATCTGGAGTACTTCGTTCCATTTTTTCTCCCAATGGAGATCTAATCCGGATTGGATAAGCGGCAGAGAGGCCTGGAATGGAGCGCGCCTGACTGAGCAGAACAGAGTCATTATCCGATTGTCCGCTGTTAGCCATCGACAGATGCCCCTACTGGATTGGGTTTTTGTTAATGAGGCCCGGGTGCCgctacaatatatatacagggGCGACCACTGGTCAGCACAACCCTAA
Protein Sequence: MDPWIRELRVEWRGGGGEAGVGIGRGCEVGPGGRGSPLVPPRPSFHSVGRVQFRIPITPSLHSTAEVVFLVSTGVCWNEMIVTPDIYFNNPRMNIGVQYDPRHSIFPNMDHHPWMSSPTPQTSPAPVIKEEPRDDAEYGQSSQDSALPLTPPPFQGYPPANAYRAATPPKDTPPASTPSPREKGEGSSNSEGEYYESGESLKRLQMALHRNGMIAEEKLQCPVCEFSCSVRSQFNEHLMSHETKCSMCDFNGETSEKLREHMRNVHDCDDDSSWGDDELNTPKVNSQGKVKTFRCKQCEFSAVTKLEFWEHSRTHIKQERLLTCPKCPFVTEYKHHLEYHLRNHFGSKPFKCDKCSYSCVNKSMLNSHLKSHSNIYQFRCADCTYATKYCHSLKLHLRKYAHSPAMVLNPDGSPNPLPIVDVYGTRRGPKQKPKQDQQPLQPQVANIFNPYSLLPTQMPYYNILNGFGGFPFPQDLNLVEKNNNVEKAEVKEDKAPLDLSCPEPTVEESSPEAPPRKRRKGKAFKLDTIALRLQQQVEVEEQQPEPTTPQHTSPPPQPTFTPPQPTLTPPQPTLTPPPELPQPTPTAPPELPQPTPTPPPEVAEPEPKSPKIESCEADSEQKPEKEEVHTHTCHGSSRSHAGISLTAGFCDGQLSWRDRSPHGGIMIWSTSFHFFSQWRSNPDWISGREAWNGARLTEQNRVIIRLSAVSHRQMPLLDWVFVNEARVPLQYIYRGDHWSAQP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -