Basic Information

Gene Symbol
-
Assembly
GCA_963457715.1
Location
OY735282.1:449102-452541[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.65 38 5.5 0.3 3 21 152 170 150 173 0.87
2 15 0.81 47 5.2 0.5 2 23 199 222 198 223 0.90
3 15 0.00063 0.037 15.0 1.6 1 23 272 295 272 295 0.90
4 15 3.2 1.9e+02 3.4 0.5 1 21 300 320 300 321 0.92
5 15 0.74 43 5.4 0.4 2 23 329 351 328 351 0.91
6 15 2.7 1.6e+02 3.6 2.7 1 13 358 370 358 381 0.89
7 15 0.0032 0.19 12.8 3.7 2 23 386 407 385 407 0.96
8 15 0.43 25 6.1 0.5 3 21 586 604 584 607 0.87
9 15 0.81 47 5.2 0.5 2 23 633 656 632 657 0.90
10 15 0.00016 0.0095 16.9 3.1 1 23 706 728 706 729 0.93
11 15 4 2.3e+02 3.1 0.6 2 23 763 785 762 785 0.89
12 15 1.2 71 4.7 2.7 1 13 792 804 792 815 0.90
13 15 0.00077 0.045 14.8 1.9 2 23 820 841 819 841 0.96
14 15 3.4e-07 2e-05 25.3 1.0 1 23 847 869 847 869 0.99
15 15 0.0051 0.29 12.2 5.3 2 23 876 897 876 898 0.94

Sequence Information

Coding Sequence
ATGGAAAACACACCTGACACTCCACAGACAGTAGCGTTGAAAAAGAAGGAATCTTTGGAACTCGCTAAGAGAACAATAACACCCTCGGATATTGTCAAGATACGAGAGTCGAAAGGAAATACGCCAATCGAAATCGCCATGAGATGCATCACAGCAGTACAAATGGCCAAGATTATGAAGTCGGGAGCCGCAATGTCTACAGAAGCTGACAAGACGAAAGGTAAACGAACTGTaaaacaggaaaaaacagaaaaagccCAGAAGAAACCTTCCAATCCGAACGCGCCAATAAAAATCGCCAAGACAAAAGAATCAAAACCGAAGAAAACAGTCGGCCAATCCAGGATTAGATTGCGAATCTGTATTGGACTGGAAAACGCTAAGATAGTATTAAAGCATTCGACGGCGTACCCCATAAAGATGGAAGTAACAGGAGACGCAGACTTGATCATATGTTCGTTCTGTGAAGAAACGTTCACAGCGATCACAGAATACCGGAGGCATTTTGACGAGAAACACAAGGAGGAAGATAAGTCTGCGCTGTTTATCAACATGCTGCGCGACCGCACGATGCGCATAGACATCACCGACCTGCGCTGTAGCGACCCAACCTGCCTCCAGACATACGAGTCGATATCGGCACTGACCACCCACCTGACAGAACACCACCGGCTGCCCATTGACCCGAGCTCACCGCCACTTCTGGTCCCGCTGCTTTTGAAAAACGACAAGTTGCAAATTTGCGTCGTGTGCAACAAAAAGTGTTATGGCATCCGCGAAGTCTCCCGCCATACGGGGGTGCACTTCGGGAGGCACACTTGCGATAAATGCGGGAAGTGTTTTGACACTATCGGGGGATTGCGCGTGCATGTAGTAAACAACCACTCCGGACACCAGTATTACTGTAGGGCTTGCAAGACCAACTTCCCGACAAACCAAGCCAGGAACACTCATTGGAAGGAGAACAATCAGTGTCGAGGGAGCAGCTGTCGCATATGCAAGGAGCGCTTCCTGAGTGCGGATCAACGCCAACGACATCTCGAAGAAGTTCACGGAGAACCAAAGAAGACCTATCCCTGTGGGGAGTGCGGGCAGGTCTTCCAAACACGCAATAAGTGTTACTTTCACTTCAAAACCGCACACATACAAGATATCAAATGCGAATACTGCAATCAAACGTTTCCCACTAAACATAAGCTCGGTGTGCATGTTCATAAGCACACCGGGCCCGGATGCGCCAGCCCGCTGGATAACTGCAAAATAATAGAACGGAGTTGGCACACACCGGTGAAAAACGTCAGGATTAAAGACACACCTTGCAATCCACAGATAGTAGCGTTGGAAAAGACCGAATCTTTGGAAATCGCTAAGAGCACCATAGCACCCTCGGATATCGCCAAAATAAGAGCGTCGGAAGACAATACACCATTCGAAATAGCCATGAGATGCATCCCACCGGCGCAAATGGCAAAGATTATGAAGTCGGAAGGCACCAAGTCTATAGAAACCGACAAGACATCCTCGAAGAAAGGTAGTCGAATTTTGAAACGGGAAATGACAGAAAAAGCCCCGAAGAAACCTCTCAACCCGAACGCACCAATACAAATCGCCAAGAGAAAAGCATCAAAACCGGATGGAAAATTCAGGTTTAAATTGCGATTCTGTATTGGACTAGAAAACGCCAAGATTGTATTAAAGCACTCTACAGCGTATCCCATAAGGATGGAAGTAACAGGTGACGCAGACTTAATAATATGTGAGTTCTGTAAAGAAACGTTCACTGCGATCACAGAATACCGGAGGCATTTTGACGAGAAACACAAGGAGGAAGATAAGTCTGCGCTGTTTATCGACATGCCGCGCGACCGCACGATGCGCATAGACATCACCGACCTGCGCTGTAGCGACCCAACCTGCCTCCAGACATACGAGTCGATATCGGCACTGACCACCCACCTGACAGAACACCACCGGCTGCCCATTGACCCGAGCTCACCGCCACTTCTGGTCCCGCTGCTTTTGAAAAACGACAAGTTGCAAATGTGCGTCGTGTGCAACAAAAAGTGTTATGGCATCCGCGAAGTCTCCCGCCATACGGGGGTGCACTTCGGGAGGCACACTTGCGAGAAATGCGGGAAATGCTTTGACACTGCCGGGGGACTGCGCGTGCATGTTGTAAACCACCACTCCGGACACCAGTATTACTGTAGGGCGTGCAAGACCAACTTCCCCACAGTCAAAGCCAGGAACACTCATTGGCAGGAGAATAATGAGTGTCGAGTGAGCAGCTGTCGCATATGCAAGGAGCGCTTTCTAAGCGTGTATCAACGCCAACGACATCTCGAAGAAGTTCACGGAGAACCAAAGAAGACCTATCCCTGTGGGGAGTGCGGGCAGGTCTTCCCAACACGCAATAAGTGTTACTTTCACTTCAAAACCGTACATATACAAGATATCAAATGCGAATACTGCAATCAAACGTTTCCCACTAAGTATAAGCTTGGTGTGCATGTTCATAAGCATACCGGTGTGCGCCCGTTCAAATGTGACGTTTGCGGAAAAACGTTTGTTGTTCACGGCGACTTGAGGAAACACATGATAACTCACGATAAAAGCAAACAGGAGCGTTGTCATGTCTGTAGTAAGACCTTTGCGAAGCGTTACAGGCTCAAACAACATATCACGGCTCACCACCCAGAATGTACTCTTGATAATGCGAATACCGCCAGCTAG
Protein Sequence
MENTPDTPQTVALKKKESLELAKRTITPSDIVKIRESKGNTPIEIAMRCITAVQMAKIMKSGAAMSTEADKTKGKRTVKQEKTEKAQKKPSNPNAPIKIAKTKESKPKKTVGQSRIRLRICIGLENAKIVLKHSTAYPIKMEVTGDADLIICSFCEETFTAITEYRRHFDEKHKEEDKSALFINMLRDRTMRIDITDLRCSDPTCLQTYESISALTTHLTEHHRLPIDPSSPPLLVPLLLKNDKLQICVVCNKKCYGIREVSRHTGVHFGRHTCDKCGKCFDTIGGLRVHVVNNHSGHQYYCRACKTNFPTNQARNTHWKENNQCRGSSCRICKERFLSADQRQRHLEEVHGEPKKTYPCGECGQVFQTRNKCYFHFKTAHIQDIKCEYCNQTFPTKHKLGVHVHKHTGPGCASPLDNCKIIERSWHTPVKNVRIKDTPCNPQIVALEKTESLEIAKSTIAPSDIAKIRASEDNTPFEIAMRCIPPAQMAKIMKSEGTKSIETDKTSSKKGSRILKREMTEKAPKKPLNPNAPIQIAKRKASKPDGKFRFKLRFCIGLENAKIVLKHSTAYPIRMEVTGDADLIICEFCKETFTAITEYRRHFDEKHKEEDKSALFIDMPRDRTMRIDITDLRCSDPTCLQTYESISALTTHLTEHHRLPIDPSSPPLLVPLLLKNDKLQMCVVCNKKCYGIREVSRHTGVHFGRHTCEKCGKCFDTAGGLRVHVVNHHSGHQYYCRACKTNFPTVKARNTHWQENNECRVSSCRICKERFLSVYQRQRHLEEVHGEPKKTYPCGECGQVFPTRNKCYFHFKTVHIQDIKCEYCNQTFPTKYKLGVHVHKHTGVRPFKCDVCGKTFVVHGDLRKHMITHDKSKQERCHVCSKTFAKRYRLKQHITAHHPECTLDNANTAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-