Basic Information

Gene Symbol
-
Assembly
GCA_963457715.1
Location
OY735282.1:360569-369237[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.013 0.77 10.9 1.0 2 23 167 189 166 189 0.96
2 13 0.049 2.9 9.1 3.4 3 20 201 218 197 220 0.92
3 13 0.051 3 9.0 0.3 2 23 229 253 228 253 0.90
4 13 0.34 20 6.4 0.0 2 21 391 410 390 413 0.89
5 13 0.017 0.97 10.5 0.6 1 20 571 590 571 592 0.95
6 13 0.75 43 5.4 0.1 2 22 620 640 619 642 0.88
7 13 0.00019 0.011 16.7 0.9 2 23 692 713 691 713 0.96
8 13 0.0014 0.082 13.9 1.2 1 23 718 741 718 741 0.93
9 13 0.21 12 7.1 0.1 2 23 749 771 748 771 0.94
10 13 0.0063 0.37 11.9 4.9 1 23 778 800 778 801 0.95
11 13 0.062 3.6 8.8 0.9 1 23 807 829 807 829 0.97
12 13 1.7e-06 9.7e-05 23.1 1.8 1 23 835 857 835 857 0.98
13 13 7.9e-07 4.6e-05 24.2 1.4 1 23 864 886 864 886 0.98

Sequence Information

Coding Sequence
ATGGACACTCTAATGATAAGCGGCATCTGCCGATGCTGCGCCTCCGAGGGGCCGTCGAAAGATCTCACAAGCAGATACAGTTGGATGGGCGATCAAGAAATATATTCCAAAATGCTGCTTGATTGCTTCGATATTTCGTTGTTGATGGAGGACGAGAGCAACAACGGCGGGATATGCGAGGTGTGCATCACCCAGCTGAGGAACGCATTCCAGTTCAAGCAGCAGGTGCAACTCACCGAGGAGAAGTTTAAGAAGACTATTAGGAGTGGCAATGTTTCTGCCATCAAACTGGAGTTGGTTCAGGAAGGTGCCTCGGACAGCGAACAAGAAATGCATGAGGAGCACCTCGATGAATCCCTAACAGAAGAGTTCGAAGTGCCGATCAAAAGGGAGTCCTCGGCCGAAGTGGAAGAGGTGAAGCCCAAGAAGCGTGCGCGAGCCGGCACCTCTAAAGCCGATCCCAAGTCGGAGCCCAACTCCTCAAAGGGTAGTGGCCTCACATGTCCGCTGTGCGCCCACCGCACCATGAGGTCGTTCAACCTCACGCGGCACCTAGCCACCGCACACGGCACCCGCATGGCCATCAGCTGCAAACTCCTATGCGCCTCATGCGGCAAGATTTTCTGCAACAACCACCGCCTCAACAAACATTTGGCCGTCGGTTGCGCAAAAAACCTCACGTTGAAATGTACAGAGTGTGTTACTCCGATCGCGTTCGAGCGCAGGTCGGACTATCTGACGCACATGCGCAGAATGCACTGGGCCGCGAGTCGCCTATTGAAGCACCACTGTCCGTTATGCGAGGACTCGTTTAGAGGCCACAAGGAGCATGACAGCCATCTCTTTAAAGTGCATAATGTCGAGTTGGACTATCAGGAGTTGACCTTCGATTCGGAGGCAGACTTGCAAGCGTGGATAGTCGACGCGGAGTCGGCGGAGGGCGCTTGTTATCTGAAGCGCCTCACAAGCGACGGCGGCGGGGAATACTTGCATTGCTATCCGGAATCGTTTCTGGGCCACGTCAAAGCGCCCGGCAAGTCCACTTGCCCGGCtagaatcgaagtgaaacgCGCATCAGATCTGTGGATGGTCACACACCAAACGAAACACCTTTGCGACATGACAACAGCGCAAACTGAGGCATGCAAGAAGAAATCAAAGACCAGATTGATCTGCCCCGTTTGTGAGATCAGCCTGAATAGTGACACAGAGTTGCGTACTCATATCGGCGATTCACACGACATTGATCTGAATGTCCAACATTTGACTTTTAACTGCCATGATGACTTTCTAACCTGGAAACGCAACATGGAGCACGACAAAAAAGTCACATTCTACAAACGATCTTCGACTGTGAGCGCCAAGAAAGGCGTACAGGTCACAAAGAGTTACTATTTCTGCTCTAGGGCCGGACCAATCAGAGCCATGCACAAAACTCACAGTCTCAGAACCGGCAAGAATTGCCCGGCCAGAGTAACTCTGAGCAAACTGGACTCGTCTCATGTGTACCAAGTGGTGTACCAAGGCACCCACGTGGGACACGAAACAGGCGCGGGGGACGGCCGCGGGAAATCAAAGAAAAAGCTAAAGAAGAAGAAATCAAAGAGCTACGATAGCGCGACGCCAGAGCGAACCGAACACAGAGTGAACCTGACGTGCATCCTGCAGTGTTCCACCGCCAGCCCCTTCCGAGACAAGACGGCCAAGGGGTTCTCCTGTCTCTACTGCGCGAAGTACTTCAAGCACATCGACGAACTACGCGCACACACCGCGCAGCAACAAGAGAAGGACAAAATCAACTCCATGATCGACTACAAACTCAGTTACAACCCCATCAAGGTCGACATCACAGGCTTGAAATGCACCCTCTGTGGTACAGACATGAAAGACTTGAACGCACTCAAGGATCATTTGGTTGGCGTCCACAATAAAACTATCAATAGAGAGATCAAAGATATCATCCTACCGTTTAGGCTAAACGACGGAACAAATTACAAATGTATCATCTGCTCCGTCGCTCACATGTCGTTTAAGAATCTGTACCAGCACATGAGCAGCCACTACAGCAACTGTTATTGCAACAAATGCGGCGTCGGGTACATCACCATAGCCGCGTTGCGGAAACACATGAAGACCCACGAGCAAGGGAGCTTCCCGTGTGAGTACTGCGACAAAGTGTACACGTCCAAGACGAAGAAGCGCAACCACGAGAAGGGCGTCCACAAGGGCAGCTGGCTCAGGAACAAGTGTCCGCAGTGTCCGGAGATCTTCGTCGGCTACTACGACAGATTAGACCACATGGTGCGAGTGCACAACGAGACGCCGATCGTCTATCCCTGCATGGCGTGCAGCAAGGtctacaaaaagaagtttgAGCTCAACCGCCACATCAAACACCACCATTTACAACAGAAGAGTTTCATGTGCGGCTCTTGCAACGCCAAGTTCTTCTCGAAGCGCGGGCTGGCCGACCACCGGTCGCGACACTTGGACGCCAGCGGGTTCACCTGCGACACTTGCGGGAAGGTCTTCTCCCGCTACAGAACCCTCCGGGACCACACGAGGATCCACGAGGAAGACCACGCGAGGTACCAGTGCGAGGTCTGCAAGAGAACCTTCTCGCAGAAGGCGAGTCTGAAGAACCACGTGAGGCTGCACCAGGACGATATGGACATATTCAAGGAGTTCGATGATGTGAAGCACCTGATTGATAATCGGGATCTGACGCTGAAGCAGATTGCCGCTGAGAATAAGACGAAAGCGACGGCCGAACTGTTGAGGCTTGGCGAGGATCCtaatacaaataatttattggaACGGTTGTGA
Protein Sequence
MDTLMISGICRCCASEGPSKDLTSRYSWMGDQEIYSKMLLDCFDISLLMEDESNNGGICEVCITQLRNAFQFKQQVQLTEEKFKKTIRSGNVSAIKLELVQEGASDSEQEMHEEHLDESLTEEFEVPIKRESSAEVEEVKPKKRARAGTSKADPKSEPNSSKGSGLTCPLCAHRTMRSFNLTRHLATAHGTRMAISCKLLCASCGKIFCNNHRLNKHLAVGCAKNLTLKCTECVTPIAFERRSDYLTHMRRMHWAASRLLKHHCPLCEDSFRGHKEHDSHLFKVHNVELDYQELTFDSEADLQAWIVDAESAEGACYLKRLTSDGGGEYLHCYPESFLGHVKAPGKSTCPARIEVKRASDLWMVTHQTKHLCDMTTAQTEACKKKSKTRLICPVCEISLNSDTELRTHIGDSHDIDLNVQHLTFNCHDDFLTWKRNMEHDKKVTFYKRSSTVSAKKGVQVTKSYYFCSRAGPIRAMHKTHSLRTGKNCPARVTLSKLDSSHVYQVVYQGTHVGHETGAGDGRGKSKKKLKKKKSKSYDSATPERTEHRVNLTCILQCSTASPFRDKTAKGFSCLYCAKYFKHIDELRAHTAQQQEKDKINSMIDYKLSYNPIKVDITGLKCTLCGTDMKDLNALKDHLVGVHNKTINREIKDIILPFRLNDGTNYKCIICSVAHMSFKNLYQHMSSHYSNCYCNKCGVGYITIAALRKHMKTHEQGSFPCEYCDKVYTSKTKKRNHEKGVHKGSWLRNKCPQCPEIFVGYYDRLDHMVRVHNETPIVYPCMACSKVYKKKFELNRHIKHHHLQQKSFMCGSCNAKFFSKRGLADHRSRHLDASGFTCDTCGKVFSRYRTLRDHTRIHEEDHARYQCEVCKRTFSQKASLKNHVRLHQDDMDIFKEFDDVKHLIDNRDLTLKQIAAENKTKATAELLRLGEDPNTNNLLERL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-