Basic Information

Gene Symbol
-
Assembly
GCA_963942445.1
Location
OZ012680.1:43974290-43976233[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 2.5e-05 0.0036 18.8 4.5 2 23 63 84 62 84 0.96
2 10 0.00026 0.037 15.6 6.4 2 23 90 111 89 111 0.97
3 10 1.8e-05 0.0026 19.2 1.5 2 23 115 136 114 136 0.97
4 10 8.2e-07 0.00012 23.5 2.9 2 23 140 161 139 161 0.97
5 10 0.0001 0.014 16.9 0.2 1 23 167 190 167 190 0.98
6 10 5.6e-05 0.0079 17.7 2.0 1 23 197 220 197 220 0.96
7 10 9.6e-05 0.014 17.0 1.6 1 23 226 249 226 249 0.96
8 10 2.8e-05 0.0039 18.7 4.9 1 23 257 279 257 279 0.97
9 10 4.5e-05 0.0064 18.0 2.6 1 23 285 307 285 307 0.98
10 10 6.5e-05 0.0093 17.5 2.2 1 23 313 335 313 335 0.96

Sequence Information

Coding Sequence
ATGGTTCGTACTGGATTGGGTTGGGGTTCTTTAAAGCGTAATGAttttgaagaagaaaataacgaaaaatatgATATAGATTTAGCAGATCGGTCGGAACTTAATAATTCGCCTGAAAATTTAGAGTTAAAAAATGTTCCAAATATATTTCCGTTTACGCTTGAAGATCTAGATGAAAAAAATCTTCGTTGTAAGTACTGTAATAAACAATTTAAGAGTAAAGTTCATTTGATTCAACATACGAAAGatcatttaaattatgttcTTACTTGTAAAATTTGTGGAAAACATACATCTAGAAAGAGCCATGCACAATCTCATAAAAAAACGCATTCGAAGCTAAGATGTGATCTTTGCAATGTCAGTTTTTCTAGTcaaaaaactttagaaaatcATACAAAAAGACATGAAATCTTGAAATGTAAATACtgtcaaaaagtttttaaaaatcaatattatattcagaaccATTTAAGAACACATACTGGTGAAAAACCATACAAATGTGATGTTTGTTCAGCAGCTTTtgctttaaaaagaaatttacaaTCTCATGTTATTACCCAACATACAggagatattaaaaattttgcttgtAAATActgtgaaagaaaatttaaaacaaaacaattactAGATTGGCATACTAAACGCATTCATTTAAAAGAAAAACCTCATCAATGTGAATTTTGTGGTCTTAACTTTGCAAATATGagtgGATTAAGACGACATAAGCTGAAACTTCATACCGAATACAACAAAAGACCGCATCATTGTAAATTATGCGATAAAAAGTTCGTTGAActcaaaaatttaacagaacATATGAACACACACACTGGCGAAAAGCCATTTCAATGTCATATTTGTTTGAAAGGTTTTGGACAACAGAGCACATTACgagaacacaaaaaattacatactgGCAAAAAGATGCACATTTGTAAAATATGTGGCAAAGCATTTGCACAACAATCAGGATGTGCAAATCATATGAAACAACATAACATGTGTAATATTTCACGTGTTGAAATTAAGCCGGGCGACTTAAACCAAAGATATTATCCACGGTCTAAATAA
Protein Sequence
MVRTGLGWGSLKRNDFEEENNEKYDIDLADRSELNNSPENLELKNVPNIFPFTLEDLDEKNLRCKYCNKQFKSKVHLIQHTKDHLNYVLTCKICGKHTSRKSHAQSHKKTHSKLRCDLCNVSFSSQKTLENHTKRHEILKCKYCQKVFKNQYYIQNHLRTHTGEKPYKCDVCSAAFALKRNLQSHVITQHTGDIKNFACKYCERKFKTKQLLDWHTKRIHLKEKPHQCEFCGLNFANMSGLRRHKLKLHTEYNKRPHHCKLCDKKFVELKNLTEHMNTHTGEKPFQCHICLKGFGQQSTLREHKKLHTGKKMHICKICGKAFAQQSGCANHMKQHNMCNISRVEIKPGDLNQRYYPRSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-