Apag002745.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Arge pagana
Gene Symbol
-
Assembly
GCA_963969455.1
Location
OZ018308.1:22387962-22390775[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.00022 0.017 15.6 2.4 2 23 78 99 77 99 0.94
2 19 4e-07 3e-05 24.2 2.6 1 23 105 127 105 127 0.97
3 19 1.8e-05 0.0014 19.0 0.4 1 23 133 155 133 155 0.99
4 19 0.0011 0.084 13.4 2.0 2 23 162 184 161 184 0.94
5 19 7.8e-05 0.0059 17.0 2.1 1 23 189 211 189 211 0.97
6 19 7.8e-07 5.9e-05 23.3 1.4 1 23 221 243 221 243 0.96
7 19 5e-05 0.0037 17.6 1.2 1 23 249 271 249 271 0.98
8 19 0.00011 0.0083 16.5 0.2 2 23 278 299 277 299 0.97
9 19 2.6e-06 0.00019 21.6 1.3 1 23 305 327 305 327 0.98
10 19 0.00012 0.009 16.4 0.4 1 23 411 433 411 433 0.93
11 19 7.1e-07 5.3e-05 23.4 1.0 1 23 439 461 439 461 0.99
12 19 4.8e-07 3.6e-05 24.0 0.5 1 23 467 489 467 489 0.98
13 19 0.00022 0.016 15.6 0.6 3 23 497 518 496 518 0.97
14 19 8.5e-06 0.00064 20.0 2.8 1 23 523 545 523 545 0.97
15 19 1.8e-05 0.0013 19.0 2.1 1 23 554 576 554 576 0.98
16 19 1.6e-05 0.0012 19.1 1.2 1 23 582 604 582 604 0.97
17 19 1.1e-05 0.00081 19.7 1.2 2 23 611 632 610 632 0.97
18 19 2.9e-06 0.00022 21.5 3.3 1 23 638 660 638 660 0.98
19 19 1.3e-05 0.00098 19.4 1.0 1 23 666 688 666 688 0.98

Sequence Information

Coding Sequence
ATGCCCCATCAAACTTTCACCTACGAAGGATGCAGGAATTTTCGTGTACCCTTAATCCGACAACTATCAAGAGTCTGCCAAGACTCGTCGTTGCTGCGTAACGAGTTGGTGGATACTTGCGTGTCGAAAGGTGTCGAAGAGAATAATTGCCCATCGAGTGGCTTCGAAATGGAGAAAAGGGAGGTGGTAGTGTCCGGAGTTGTGACAGAGTCGACGGAGAGGAATCGTTGCGAATGCGAAGACTGCGGAAAGGTATGTGGTAGCAAAGAATTGCTGCGGAAGCACAAGGTCGTGCACAGCAACGTCTTCAGACACAGCTGCGACGTGTGCGACAAGAAGTTCAAGCGTTCCAACGAGCTGAAGGTTCACATGAAGGTTCACTCCCGTGACAAGGAATACGAGTGTCCAGTTTGCGGTACAGGATTCAAGCTACGCTCACAAATGATGATCCATCGGAAACGACACACGACGGATTACCAGATAACTTGCGAGCTCTGCGACAAGGGTTTTCACACCAGCGGTGACTACAAATCTCACCAGTTTTCCAAGCACGGCGTAAGTCCACATGTTTGTTCGATTTGCCGCAAAGTCTTGCGCAGCAAGAGTATGCTGGAGAAGCATGAGAAGTCTCATCAACCCGACTACGTCGTGGAAAGGCCACATCAGTGTGAGATCTGTGGGAAAACCTTCGTGACGAAGAAGTCTTTGAAGCTTCATGTTCAAGCTCATACCGGGGAGAAGCGATACACTTGCGACGAATGTGGCAAGAAAGTTAGAACTCATGCTTCGCTCGTGGAACACAAACGACTGCACACAGGCGAAAAACCCGTGGTATGCAGCGTTTGCAAAAAAGGATTTGCCAAACGTTCTACTATGGTCGTACACGTCCGGACCCACACCGGAGAACGACCCTACAAATGCGACGTCTGCCAAAAAACTTTTACTCAGAGAACAAGCCTCGTTATTCATGCACGATATCATTCCGGTGATCGACCCTATTCTTGCTCCTTgtCAAGCTTGAAAGTAGAGGAGATCGAGATCGAGGAAGGAGCTAAGATCGATAAAAAGTACGATGCTTCGGAAGATCAGGACATATCGGAGCCACGGCAAGCCTCGGTGTGCAAACGTTACGAGAACTGTGGAACAAGCGACACGAAGGATCCGCTGATCTTTGGATCGAAGTACACGACAGAAGCTGCGAAAGAAGATATTTATCCCGTGAAGAAATCTTATCAGTGTGAAATATGCTCGAAGATGTTCAGGTCGAAGAACTTGTTCGAGGGTCACTTGGTGGCGCACAGCGATGCCAGACCTTACCGCTGCGACGTCTGTGGAAAGACGTTCAAGCGGACGAATACTCTGGCAGTCCACAAGCGGATTCACACCAGGGAGAGAAATTTCGTCTGCGACGTCTGTGGCCGTGCCTTCATTCAGGCATCCCAATTGGCTACCCATCATCGTAGACACTTCGAGAAGTACACGAAGTTCTGCGATGTATGCAAGAAAGGATTTTTCACCAATGCCGAGCTGAACGGACACATGAACATGAAGCACGAGGCCAAAGAGCACGTCTGCGAGAGCTGTGGCAAATCGTTTCCCAACAACCACACGTTGGTAAGGCATACCAAGGTGCACGAGCCAAACTTCAGGCCCGTCAAACACCAATGTGAGTTTTGTGGGAAGACCTTTGCCTACAAGAACTCTCTGGTCCTCCACGTCAAGTCGCACACCGGAGACAATAAGTTCGATTGTCATCTGTGTGGCAAGTCTGTATCCTCCAAAGGATCCCTCTACGATCATCTTCGACTCCATGGCGGTGAGAAATCCCTGGTTTGCGACGTCTGTGGCAAGGCATTCCACAAACGTAGCACGCTCGTCGTCCACAAGAGAACACACACCGGAGAGAAACCCTACAGCTGCGAGACCTGCGGCAAATCTTTTACCCAACACTCGACTCTCGTCATCCACAAGCGATACCACACCGGCCAAAGACCTTATCAATGCACCTTCTGTACCAAATCATTCGTGTCGAGAGCTTTGTTGAATGCTCATAACAAGGTTCACGCCAGCGCGGTGCAGCTAGCGTAG
Protein Sequence
MPHQTFTYEGCRNFRVPLIRQLSRVCQDSSLLRNELVDTCVSKGVEENNCPSSGFEMEKREVVVSGVVTESTERNRCECEDCGKVCGSKELLRKHKVVHSNVFRHSCDVCDKKFKRSNELKVHMKVHSRDKEYECPVCGTGFKLRSQMMIHRKRHTTDYQITCELCDKGFHTSGDYKSHQFSKHGVSPHVCSICRKVLRSKSMLEKHEKSHQPDYVVERPHQCEICGKTFVTKKSLKLHVQAHTGEKRYTCDECGKKVRTHASLVEHKRLHTGEKPVVCSVCKKGFAKRSTMVVHVRTHTGERPYKCDVCQKTFTQRTSLVIHARYHSGDRPYSCSLSSLKVEEIEIEEGAKIDKKYDASEDQDISEPRQASVCKRYENCGTSDTKDPLIFGSKYTTEAAKEDIYPVKKSYQCEICSKMFRSKNLFEGHLVAHSDARPYRCDVCGKTFKRTNTLAVHKRIHTRERNFVCDVCGRAFIQASQLATHHRRHFEKYTKFCDVCKKGFFTNAELNGHMNMKHEAKEHVCESCGKSFPNNHTLVRHTKVHEPNFRPVKHQCEFCGKTFAYKNSLVLHVKSHTGDNKFDCHLCGKSVSSKGSLYDHLRLHGGEKSLVCDVCGKAFHKRSTLVVHKRTHTGEKPYSCETCGKSFTQHSTLVIHKRYHTGQRPYQCTFCTKSFVSRALLNAHNKVHASAVQLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-