Apln013527.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Arctia plantaginis
Gene Symbol
ZEB2
Assembly
None
Location
CADEBC010000557.1:95963-120561[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.026 1.6 9.4 1.4 1 21 198 218 198 221 0.90
2 11 0.0018 0.11 13.0 0.5 1 23 228 250 228 250 0.94
3 11 0.29 18 6.1 0.8 3 23 256 277 255 277 0.94
4 11 0.0077 0.48 11.0 1.0 2 23 281 303 280 303 0.96
5 11 4.2e-06 0.00026 21.3 6.2 1 23 306 328 306 328 0.98
6 11 0.0067 0.41 11.2 0.2 1 19 332 350 332 350 0.97
7 11 0.087 5.4 7.7 0.3 3 21 367 385 366 386 0.94
8 11 0.0042 0.26 11.9 0.3 2 23 402 424 401 424 0.95
9 11 0.82 51 4.7 5.8 1 23 430 453 430 453 0.93
10 11 0.00022 0.014 15.9 0.2 3 23 464 484 463 484 0.99
11 11 0.0038 0.23 12.0 4.3 1 23 490 513 490 513 0.96

Sequence Information

Coding Sequence
ATGAAGTTAAAAGATCAATTTGCGCAAGAGAATAGGCAACACGAGGGATTTCAGGTTACAGAGACAACAGGTTTCGTGATTAGAAAGTCTCCGACTCTCAGAgacccaagtGTGTCTCAACATGTCCAGCTGTGCTGGGAATGTATGGCGATGCTGAAGAAGATCAAACTGTTCAAGTCCAGGGTAGAAGAGGCACAGAGAACAATATCACACCAATTTATTCACAAACAGaaaaatACAATTAGAAGTCTATCGAGACTATCACCcatttcaacaaataatatcatatttataacTCATAATGATAAAGAAACAAGTTcaataaaacatgaaatacaTGACTCagaagataattttaattataatgaaatagaCTCTACAAGTGATCATGTAttcgaaattaaaaaagaaagaagacctgccattaaaagtaaagtattgAAAAGTCAAAAGAGGTCACATTACAGATTAGTCTATGGtccaaatgtttataaaaagagCTTATTGAGAAAGAAGTTTTCAATCAAGCCTACAGATGTACCATTATGGTTGGAGAAAGATAAATGtagtcaatattttaaaacgtgCAGGTTCAGATGCAGAATGTGCTTTGAAGGATTCAATTCTAAGGAGAAATTGGACAGACATAACTCGGCGCGCCATGCTGAGACTCTTGGTCCACACATTTGCCCCACGTGCAGGGCGCGCTTCCCTACAGAGGACTCGCTGGAGGCCCATGTCCACGAGCACATGTTCGCGCGAGCGTGCGCTCGTTGCGGCTTCGAGTGCTACACACTGCGGCGGCTGAACGCGCACATCATGCTTACGCACAAACTGGTCCAGTGCGTCTACTGTGGCCTGTGTCTCCCGAACGTGCGTGAGTTTCGCAAGCACTACCGAGAGATGCACAGCGTGTTCGAGTGCGACCACTGCGGCAAGCGGTGCAAGACCAAGTACATGCTGGAGAAACACATGAGTAGCCACTCGCAGCGCCACTCGTGCGGTCGCTGCGGGCGCGAGTACGCGAGCCGCGCGGCGCTGCGCAAGCACGACGCCGCCAAGCACGCGGCGCGCGGGGCCAAGCCCGAGGACGCGTACTGCGTGCTCTGCGACAAGCAGTTCCACAGCGCGCCCGTCTACCGCCGCCACCTGCGAGACGCCACCGCGCACGCGCACGAGACCGCCAGCTCGGTCAAGAAGGTGCCGTGTCCAGAGTGCGGCAATTTGTACTCGCGGCGAGCCTACATGATGAACCACTACCGACACGTACATATGAACCAGTCCAAATACTACTGCTCGCACTGCGACCGGCACTTCCTTAACCGCACCCGTTACGTGGAGCACGTGCGGTACAACCACGAGGGAGCCAAGAAGGAGAGGAACAAACTGTGCAACGTCTGCGGCCGAGGGTTCGCGACCAATCGGATCCTGGCGAACCACATCCGGACGCACTCCGGCGAGCGGCCGTTCGAGTGCGAGCACTGCTCGGCCAAGTTCACGCAGAAGCACTCCATGCTGTCGCACGTCAAGTACATACACATGAAGGGCAAGCGTCGCCCCACTTGGCAAACACGAGACGCACAATAA
Protein Sequence
MKLKDQFAQENRQHEGFQVTETTGFVIRKSPTLRDPSVSQHVQLCWECMAMLKKIKLFKSRVEEAQRTISHQFIHKQKNTIRSLSRLSPISTNNIIFITHNDKETSSIKHEIHDSEDNFNYNEIDSTSDHVFEIKKERRPAIKSKVLKSQKRSHYRLVYGPNVYKKSLLRKKFSIKPTDVPLWLEKDKCSQYFKTCRFRCRMCFEGFNSKEKLDRHNSARHAETLGPHICPTCRARFPTEDSLEAHVHEHMFARACARCGFECYTLRRLNAHIMLTHKLVQCVYCGLCLPNVREFRKHYREMHSVFECDHCGKRCKTKYMLEKHMSSHSQRHSCGRCGREYASRAALRKHDAAKHAARGAKPEDAYCVLCDKQFHSAPVYRRHLRDATAHAHETASSVKKVPCPECGNLYSRRAYMMNHYRHVHMNQSKYYCSHCDRHFLNRTRYVEHVRYNHEGAKKERNKLCNVCGRGFATNRILANHIRTHSGERPFECEHCSAKFTQKHSMLSHVKYIHMKGKRRPTWQTRDAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00823417;
90% Identity
-
80% Identity
-