Basic Information

Gene Symbol
-
Assembly
GCA_963662175.1
Location
OY759216.1:58771660-58779252[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.00014 0.024 16.5 1.5 1 23 160 183 160 183 0.97
2 17 6.6e-05 0.011 17.5 1.4 1 23 187 209 187 209 0.98
3 17 0.045 7.8 8.6 0.8 2 19 337 353 336 355 0.93
4 17 0.017 2.9 9.9 0.5 2 20 391 409 390 414 0.91
5 17 0.0022 0.38 12.7 0.1 2 21 491 510 490 511 0.94
6 17 1.2 2.2e+02 4.0 0.4 2 22 515 535 514 538 0.88
7 17 0.00091 0.16 13.9 4.7 1 23 576 598 576 598 0.98
8 17 0.0068 1.2 11.2 0.2 3 23 607 628 606 628 0.96
9 17 0.15 26 6.9 2.8 1 23 633 655 633 655 0.92
10 17 0.023 3.9 9.5 0.5 2 23 660 682 659 682 0.94
11 17 0.014 2.4 10.2 2.0 2 23 687 708 687 708 0.97
12 17 9.7e-05 0.017 17.0 0.4 2 23 715 736 714 736 0.96
13 17 0.00037 0.064 15.1 0.5 1 23 742 764 742 764 0.97
14 17 0.29 50 6.0 4.5 1 23 770 792 770 792 0.98
15 17 1.9e-05 0.0033 19.2 1.2 1 23 796 818 796 818 0.98
16 17 6.8e-08 1.2e-05 26.9 0.5 1 23 824 846 824 846 0.98
17 17 0.022 3.8 9.6 1.8 1 23 852 875 852 875 0.94

Sequence Information

Coding Sequence
atgcgaCCAAAAAGTAAACAAAACGAAATGGGTGAAGTGCATCGGCATGCCTATTCCTGTTTCATTTGTGATGAAGGAGAACAGGAGACGGGCCTAAGACTTCTAAAGTCCCAAACTGCTTTTTCAAGAATTACATTGGGCGAAAAGCTTCAAGAAATCCTTGGGAATACTTATGTTGTACTATTGTCAGGGAAAGATCGAGTCTGTTGGGATTGTGCTTCATCTATAAACTGGGTCGATCGAACCGAACACAAACTGAATCTTGTCAAGGATTATGTACTAGATAAAGTTATCCATAAGTACAAGCGCAAGGAAATCGCACTCGGTGAGATACCAGACACACCAGAACAAGTTGGCACTCAGCAagTGTCAGTGGAAGTACCAGAACCACCTCCAACTCCTTTACCTGCAATCAAAAAGGAATcgCTATTTGCGGAGAAACTGGAAGAAGTAAAACGTCCCAGAAAGAAGAAAGATTATATGTGTAAATATTGTGAAAAGAAGTACGCAACGTTGGTAACCCTGACAATGCACATTCAGAAGTTCCACTCAGCTCGGTTCGAGTGTTCGCTCTGCGACCAGCGGTTCCAAACCCAGGCCAAACTGAAGAAACACGAGAAGGTGCACATGTACGGACCCACGGACAAGAACCTTACCTGTGTCTCTTGCGGGTTTCAGACCACCAACACCGAAGTCTATTGCCGGCATGTCTGCAATTCCAATGTGGTCTCTCTGTCTTGTATCTCCTGCAAGAAAAGATATTTGGATACCAACTTTCGACAAGATACTGGTTCATACAAGTGTAAGATTTGTACAACCAAGGAAGAGGTGGCTCGAGAAGAGGCGCTGATAACTGAAGGGCCAATGGAGCACGGCCGCCCTGCAGAAATTGTTGTTTCTTCTGAcatagctgaggaaatgccggaGTTTTTAAGAATGGGGGGGGATATGAAGGAACAGGGGGAGGTTGGATGGGAAGGAGAAGAGGAGGAGGACTGCTCGTTCCTGCGGTGCGAGGGCTGCGGGGAGCAGTTCAAGTTGAGCGACCTGACCAAGCACGGTTGCTTCCTGAGGGGGGACGCCGTGGAGTATGTGGAGGTGGAGCCACCGACATTCCTGGTTCCCCAGCCGCCCTCCAGGAAGAGAACAGCCCCCGAGGTCACCTATCTCCAGTGTAAAGACTGCGACGCTCAGTTCAGACTTATAGAACATCTCCGGAATCACTGGGACCAAACAGGACACATCAGAGAGGTGAACACACCTTCGGAGGAAGTGAATAGAATTAAAGATAAATTGAAGAAGACTGAAGCCACTTTCAAAGTGGTCAAACAGAACTTTAATATCAGGGCCACGATACCTGGCAAAAATGAGGAAGTTTTGCGCTCTGGGGAGGACTATAAAGATATTTTTGTTCGAGTCAACAAACAACAGGACACAATTGaagaatttgaaaagaaaaaagatgGCAAGGAATGCGAAACTTGCGGAATTATATTTTCCAATGAGGAGTTGCTCCTTCAACATCAGAAACTGGACTGTCTGACTTGTGTGACATGTGCAGTGACCTTTCTGGACAACAAACTTCTCAAGAGACACTACCAGTACACAGGGCATGCGAGTGTTGTGAATCGGCAGCTGTATGAGGAGACGTCAGCTCCGGGTGTCGTATACCATCAGGAACCAGAGCAGCAGCAGTCTCTCATCAAGACACCCATCGCCCTCGGCTTCAAGTGCCATCGCTGTGCTAAAGTTTTCCCATCCAGATTTCTTCTCCGAAAACACTTTAATTCTCATTTTAAAGGGACCACTAAAGGAGCTTGTCAGTATTGTTTGAGGGAATTTGATACCAAGGAAGATGTTCAGTCGCATATTCTGCGTGAACATGGTGCTCACACCTATGAATGTAGCTTTTGTAATAGAACATTTATGTCTGAGAATTTTAAAAGGAAGCATGAAGCAAAGCATAGGCCCCCACTTCGTTGTGATGCTTGCGATATTAAATTCAATACTGAAAAGTCTCTTCTTCTGCATTATGAAAGGAAGCACGAGGGGGGTGGGACGTGTCGTCTTTGCGACAAACAGGTCCATGATCCCATCTCTCTCCGGAGGCATGAGCGGAGACACTACTTCGACAGGGGACTTGAGTGTGACCTTTGTCAGAAGAAGTTCAAAAATAAAGCTTTACTTGTGGCTCATTCGAAAGTGCACGTGGGAGAAGTGAAGTTCCAGTGCGAGGTTTGTCATCTTGGGTTCGCCAGTGAGGACTCACTCAAGGAGCACAAGGCTAGCCATCTCGGACGGGGCAAGTACCGGTGTCCCAAGTGCCACCTCCTTTGTTCCAACTATGCCTCCTACTGGATGCACTCCAAGATGCACGAGGCCAGCTACGCCTGCACTGTCTGCAAGAGGAAGTTCCGGGATACTTCGCTCCTGGCGGTCCATAGAAGGAAGCACCTCCGGAGCCGACCCTATCAGTGCCCCAAGTGCCCCCGTTCTTTCTCCGTCCCCTCCACCCTCCGACGTCACATGTATATACATTCCAGAGTGTTCCCGTTTACATGCCAGGTCTGCAGTCGAGGCTTCCTCACTCAGTCTGCTTATCGTAAACATGTTCAGTTCAAACACGGGACAGGAGGGGAGGCGAGAAGACGGAGCCTCACCACAGGTAGAGCCAACACTCACCTACCTCCCAATGCCTCCGATGAAGACATCCTCCACGCAGCAGATGATCTCATTGATAACTCCATTATGTTCAACGATTATCAGAACAAAGACATTGATCACGTATCCAATGATCTCATTTCTAACGAAGTTGTTGTAGAAACAACTGAATTGTTTGAACAAATCCTTCATTGA
Protein Sequence
MRPKSKQNEMGEVHRHAYSCFICDEGEQETGLRLLKSQTAFSRITLGEKLQEILGNTYVVLLSGKDRVCWDCASSINWVDRTEHKLNLVKDYVLDKVIHKYKRKEIALGEIPDTPEQVGTQQVSVEVPEPPPTPLPAIKKESLFAEKLEEVKRPRKKKDYMCKYCEKKYATLVTLTMHIQKFHSARFECSLCDQRFQTQAKLKKHEKVHMYGPTDKNLTCVSCGFQTTNTEVYCRHVCNSNVVSLSCISCKKRYLDTNFRQDTGSYKCKICTTKEEVAREEALITEGPMEHGRPAEIVVSSDIAEEMPEFLRMGGDMKEQGEVGWEGEEEEDCSFLRCEGCGEQFKLSDLTKHGCFLRGDAVEYVEVEPPTFLVPQPPSRKRTAPEVTYLQCKDCDAQFRLIEHLRNHWDQTGHIREVNTPSEEVNRIKDKLKKTEATFKVVKQNFNIRATIPGKNEEVLRSGEDYKDIFVRVNKQQDTIEEFEKKKDGKECETCGIIFSNEELLLQHQKLDCLTCVTCAVTFLDNKLLKRHYQYTGHASVVNRQLYEETSAPGVVYHQEPEQQQSLIKTPIALGFKCHRCAKVFPSRFLLRKHFNSHFKGTTKGACQYCLREFDTKEDVQSHILREHGAHTYECSFCNRTFMSENFKRKHEAKHRPPLRCDACDIKFNTEKSLLLHYERKHEGGGTCRLCDKQVHDPISLRRHERRHYFDRGLECDLCQKKFKNKALLVAHSKVHVGEVKFQCEVCHLGFASEDSLKEHKASHLGRGKYRCPKCHLLCSNYASYWMHSKMHEASYACTVCKRKFRDTSLLAVHRRKHLRSRPYQCPKCPRSFSVPSTLRRHMYIHSRVFPFTCQVCSRGFLTQSAYRKHVQFKHGTGGEARRRSLTTGRANTHLPPNASDEDILHAADDLIDNSIMFNDYQNKDIDHVSNDLISNEVVVETTELFEQILH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-