Basic Information

Insect
Aquatica leii
Gene Symbol
-
Assembly
GCA_035610365.1
Location
CM069438.1:18263361-18264556[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.46 1.1e+02 6.2 1.6 1 23 131 153 131 153 0.97
2 9 0.0056 1.3 12.2 7.6 1 23 161 183 161 183 0.99
3 9 0.00012 0.03 17.4 8.1 1 23 189 211 189 211 0.99
4 9 3e-05 0.0071 19.4 3.8 1 23 217 239 217 239 0.99
5 9 0.0016 0.39 13.9 6.4 1 23 245 267 245 267 0.98
6 9 1.7e-05 0.0041 20.1 4.1 1 23 273 295 273 295 0.99
7 9 5.6e-05 0.013 18.5 0.8 1 23 301 323 301 323 0.98
8 9 0.0002 0.047 16.8 7.8 1 23 329 351 329 351 0.99
9 9 3.1e-05 0.0074 19.3 3.3 1 23 357 379 357 379 0.99

Sequence Information

Coding Sequence
atggaaaaaaaatcaacaaaagctTGTCGAATCTGTTTACTAAAAATAGTAGAAACCGAACAGTTATACTTTCTGAATAACGACAATaagttaatgctacaattcaaattgttgaactttCTACCAGAAATTGATCTAAATATCACACCGAACCcaattgtttgtaataaatgtgTGATTgctattgaagaaatatatgaatttaagcaattGTGTATACAGACTGAAATGACCATAAGACACTTACGACAACAAGGTGCAATTAAAGAAGAGTTGCATGTCGATAACATTAAAGTCGAACTTTCAAACTTACAAATCATCCCCGATAAATATGTGGAAGTCAATAAGGATTTGCCCGTATGCATTGAGGAACCTTCGAAAACAGAAATGTATAattgctacaactgcaactTCTATACTAATAAAAAGAAGGTTTTGATTCAACACCTACTGGTTCATAAATACACTGATGAaaagccatttaaatgcaataaatgtgattactgtagtgaGATCAAGTCCCgattaaaaaggcatatgcatacgcacactggtgagaaaccatttaaatgcaatatatgtggtTACTGCTGTATCACCAATACggctttaaaaacgcatatgtgtaaacacactggtgaaaaaccatttaaatgtaatctatgtgattactgctcTACTGCCAAGTcggatttaaaaaggcatatgcttaGGCACACTGgggaaaaaccatttaaatgcaatatatgtgatcatTGTAGCACTCGATTGAcacttttaaaaatgcatatgtatAAACACAGTGGTGAAAAACcctttaaatgcaatatatgtgattacagtTCTTCCAGCAAGTTTCATCTTAAAATTCAtgtgcgtaagcacactggtgaaaaaccgtttaaatgcaatatatgtgattactctaGTAGTCAAGTGGGACTTTTAAATAcgcatatgtataagcacactggtgacaaaccgtttaaatgcaatatgtgtgattactgTTGTAACTCCAAATTTACCTTAAAAGTGCATATACGtaggcacactggtgaaaaactatttaagtgcaatatatgTGGTTACTGTAGTAACGAAATGGCAactttaaaaaggcatatgcgtaagcacactggcaAGTAA
Protein Sequence
MEKKSTKACRICLLKIVETEQLYFLNNDNKLMLQFKLLNFLPEIDLNITPNPIVCNKCVIAIEEIYEFKQLCIQTEMTIRHLRQQGAIKEELHVDNIKVELSNLQIIPDKYVEVNKDLPVCIEEPSKTEMYNCYNCNFYTNKKKVLIQHLLVHKYTDEKPFKCNKCDYCSEIKSRLKRHMHTHTGEKPFKCNICGYCCITNTALKTHMCKHTGEKPFKCNLCDYCSTAKSDLKRHMLRHTGEKPFKCNICDHCSTRLTLLKMHMYKHSGEKPFKCNICDYSSSSKFHLKIHVRKHTGEKPFKCNICDYSSSQVGLLNTHMYKHTGDKPFKCNMCDYCCNSKFTLKVHIRRHTGEKLFKCNICGYCSNEMATLKRHMRKHTGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00154001;
90% Identity
-
80% Identity
-