Basic Information

Insect: Aquatica leii
Gene Symbol: zfh1
Assembly: GCA_035610365.1
Location: CM069433.1:95740555-95748357[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0054 1.3 12.2 0.2 2 23 54 76 53 76 0.96

2 9 0.0027 0.64 13.2 0.2 3 23 108 128 106 128 0.95

3 9 1.4e-05 0.0034 20.4 0.6 2 23 135 156 134 156 0.97

4 9 9.2e-06 0.0022 21.0 5.9 1 23 165 187 165 187 0.99

5 9 0.00022 0.052 16.6 1.0 1 21 193 213 193 214 0.95

6 9 0.034 8.2 9.7 3.6 1 19 458 476 458 478 0.94

7 9 1.1e-05 0.0027 20.7 1.5 1 23 833 855 833 855 0.94

8 9 0.041 9.7 9.5 9.7 1 23 861 883 861 883 0.98

9 9 0.0043 1 12.6 4.3 1 21 889 909 889 910 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0054	1.3	12.2	0.2	2	23	54	76	53	76	0.96
2	9	0.0027	0.64	13.2	0.2	3	23	108	128	106	128	0.95
3	9	1.4e-05	0.0034	20.4	0.6	2	23	135	156	134	156	0.97
4	9	9.2e-06	0.0022	21.0	5.9	1	23	165	187	165	187	0.99
5	9	0.00022	0.052	16.6	1.0	1	21	193	213	193	214	0.95
6	9	0.034	8.2	9.7	3.6	1	19	458	476	458	478	0.94
7	9	1.1e-05	0.0027	20.7	1.5	1	23	833	855	833	855	0.94
8	9	0.041	9.7	9.5	9.7	1	23	861	883	861	883	0.98
9	9	0.0043	1	12.6	4.3	1	21	889	909	889	910	0.96

Sequence Information

Coding Sequence: ATGGTGGCGCGTAGTGAAAGCATGTTTGGGTGCTACGATAGCTACTCGTACAGACTCTGGAGCCTCGCCAACGTATGGAGCACCTGTCAATttCCATCTATAACGAACGGTTTAACcaaagaagtagaagaaataaATTCGAATCccgaatattttataaaatgtccAAAGTGCCAAAAAGGCTATCCAGGTTTCCAAGCTTTAAAGGAACACATGGAATCGACGCATACAGATATAAGTTCCGTAGAAAATACAACGGGGATAATTTCTAACTCGGTTTCTCCTACGCCAAGTATCATAGGCTCCGGTGGTCCTTATGGATGTTCTCAATGTGCGACATCGTTCGCCTCAAAAGATCAATTGGAGAAACACGAACTTTTACATTCTCCCAATGCTCAAGTGtcatgcaaaatttgcaataaaacttttgcaaatGTATACCGTCTGCAACGACATATGATAAGTCACGACGAAAGCgcagttttaagaaaattcaaaTGCACCGAATgtgaaaaagcatttaaattcaAGCATCACTTAAAGGAACACATACGTATACACAGTGGAGAAAAACCGTTTGAATGTGTGAACTGTGGAAAACGTTTTTCGCATTCCGGATCATATTCTAGTCACATGACGTCAAAGAAATGTTTGGTGATGAATTTGAAATTGGGGCGTACACGTGGTTCGCCCGGTAACGCGTTGCTCGAAAAATCCCCGTCGCAGACCAGTAGAAGTAATAAAAGAATACCCGGAAAtccattaaataataatttaactacaaGCCCTAATCATAACGCGTATTTACCTATTCTTCCTAAATATACCGAAGCCGCCGCTGCCTTTTTGCACAGTTCTCTTGCCAGTAACCACGCTATACATCCTTTCTATATTCCTCCTACCAGTTTATTAAACAATTCTGGTCCAACTATTAGTCCTTACTCCGTGCCCTCGTTAAATCATATTTTGGAACAACTACAAGGAGCATCTCCACACCGTCCACAATTTATAGAAGCCCCAGAAGATATGAGTGTATCTAATTCAatagaaaatctaaaacaagAAACCACAACTTCGCCAAAGATAAACGATTCGATAACTGCCGGTTCTAAATCAAACTCTTCTAGCTGTGGCGATTTAGTAGTTGCGAGTGACGCGGAAAATGCTAACGATACGGAAAtctcaataaaaaaagaatgcaaTTCCGGAGACATCAACAGCAACGGTAGCGACTTAGAAGCGGTAAAACGTATTTTAGAAACCGTCAACGCATCTGTAACCAAACAGTTGTTGCAGGCCAACATGCAAAAATATACGAACGATGCAGACAGCGATGATAGAACTTCTCCAAGTCTTAAATCTCCAAACGAATTTACTTGCACTATATGCAAACAACACTTTTCTAATCAACGAACTTTAGATGACCACGAATGTGATCAAATCGATATCCAGAGTGAAGGTTTAGCCGCGAAACTAGAAGATGCCGTTACTATTAAAGTTGAAGACACGCATAATAGTAATTATAGCTGCGACGAATATGATTTGGACTCAGATCGTTTATTGGATAAAAACGACGATTACGATATGGATTGTGAGTCTGTTACTACGACCGATCAAGTATCTGAAGATGGTCGAAAAGTAAGAGTGCGTTCATTAATTGCGGACAAACAGTTGAAAGTACTAAAAGATCACTATAATATGAATCCTAGACCTAGACGAGAAGAGTTAGtaaaaattgcagaaaaaattGGATTTCCAGTTAGAGTTGTTCAAGTTTGGTTTCAAAATACAAGAGCTAGAGATAGACGAGAAGGTAGATTAATACAAGTACCATATAATCCTATGGGATCTGTGCCGTTAAGATTACCCCCAGCAATGGTGCCTTCTAGCTCACAGTCGTCTGGACTTCGAGTTGGTTACCCTTTAGTTTCTTCTCCGCCATATAATCTAGAACAGCCTTTAGATTTATCTACCAAAAAAAGTCCACTACTATCGACGCACTCTTCTCCAAGTGGTTCGCCACATAGACCACCATCTTCAAATCCACATTCTGATTCGGGAGAAGAAGTTGTCAATTTAAGCCATAAATGTTCTCGCAGTCCAACACCGTTTCATCAATCATACCAAAACCATTACCAGAACTCAAACTCTTCCTCAGACCTTCGTCGCTCTCCTTCTCCTATGGATTTTAATAACGGTAGCAAACTCGCAAAAATTTTGGCTCAACCTACACATCCGCTTTCGTTGTCCAATGTAGGACTGGTTCCTATGGATGGGTTTATGCGTTTGCCAgcattaacacaattaattaacaacagaatttCTAATTTAAGTCCATCATCCGGTAAACGGTGTTGGAGCGAAGAAAACGAATCTACAGTTCCTCAAGACGCATTGCACGACCGTTTAAATAAAAGGACTAAAGTTACGCAAATTGTCTTAAAAGGTTTGAACAGTCCAAGTCTCTTAAACGCTGAAGGGGAAATAGAAGGCCAATTTATTTGCGACCAATGTGATAAGTCATTTACCAAACAGAGTTCGCTCGCTCGACATAAATACGAACAttcagGACAACGTCCTCATAAATGTGACGAGTGTATTAAGGCATTTAAGCACAAACACCATTTAACCGAACACAAACGGCTACACAGTGGAGAAAAACCGTTTCAGTGCAGCAAGTGCCTCAAACGCTTTTCACATTCAGGATCTTACAGTCAGCATATGAATCACCGCTACTCGTATTGCAAACCGTATAGAGAGTAA
Protein Sequence: MVARSESMFGCYDSYSYRLWSLANVWSTCQFPSITNGLTKEVEEINSNPEYFIKCPKCQKGYPGFQALKEHMESTHTDISSVENTTGIISNSVSPTPSIIGSGGPYGCSQCATSFASKDQLEKHELLHSPNAQVSCKICNKTFANVYRLQRHMISHDESAVLRKFKCTECEKAFKFKHHLKEHIRIHSGEKPFECVNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRTRGSPGNALLEKSPSQTSRSNKRIPGNPLNNNLTTSPNHNAYLPILPKYTEAAAAFLHSSLASNHAIHPFYIPPTSLLNNSGPTISPYSVPSLNHILEQLQGASPHRPQFIEAPEDMSVSNSIENLKQETTTSPKINDSITAGSKSNSSSCGDLVVASDAENANDTEISIKKECNSGDINSNGSDLEAVKRILETVNASVTKQLLQANMQKYTNDADSDDRTSPSLKSPNEFTCTICKQHFSNQRTLDDHECDQIDIQSEGLAAKLEDAVTIKVEDTHNSNYSCDEYDLDSDRLLDKNDDYDMDCESVTTTDQVSEDGRKVRVRSLIADKQLKVLKDHYNMNPRPRREELVKIAEKIGFPVRVVQVWFQNTRARDRREGRLIQVPYNPMGSVPLRLPPAMVPSSSQSSGLRVGYPLVSSPPYNLEQPLDLSTKKSPLLSTHSSPSGSPHRPPSSNPHSDSGEEVVNLSHKCSRSPTPFHQSYQNHYQNSNSSSDLRRSPSPMDFNNGSKLAKILAQPTHPLSLSNVGLVPMDGFMRLPALTQLINNRISNLSPSSGKRCWSEENESTVPQDALHDRLNKRTKVTQIVLKGLNSPSLLNAEGEIEGQFICDQCDKSFTKQSSLARHKYEHSGQRPHKCDECIKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00001824;
90% Identity: iTF_00001824;
80% Identity: iTF_00152141;