Basic Information

Insect
Aquatica leii
Gene Symbol
-
Assembly
GCA_035610365.1
Location
CM069438.1:23164044-23165448[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 6.7e-05 0.016 18.2 3.3 1 23 163 185 163 185 0.99
2 10 8.9e-06 0.0021 21.0 0.7 1 23 191 213 191 213 0.99
3 10 1.1e-05 0.0026 20.7 2.3 1 23 219 241 219 241 0.99
4 10 1.1e-05 0.0026 20.7 2.3 1 23 247 269 247 269 0.99
5 10 1.1e-05 0.0026 20.7 2.3 1 23 275 297 275 297 0.99
6 10 1.1e-05 0.0026 20.7 2.3 1 23 303 325 303 325 0.99
7 10 1.1e-05 0.0026 20.7 2.3 1 23 331 353 331 353 0.99
8 10 1.1e-05 0.0026 20.7 2.3 1 23 359 381 359 381 0.99
9 10 1.1e-05 0.0026 20.7 2.3 1 23 387 409 387 409 0.99
10 10 3.2e-05 0.0077 19.3 3.5 1 23 415 437 415 437 0.99

Sequence Information

Coding Sequence
atggGAGAAagatcaacaaaaatttgtcgaatttgttcactAGAAATAATAGAAGTGGAGCCCTATTACTTTCTGAATAATGACACTAATTCaatgctacaattcaaattgttgaagcTTCTACCtgaaattGATCTAAACATCACAACAAATCCAATTGCTTGTAAACGATGTATGATtgcaattaaagaaatatacgAGTTTAAACAATTGTGTATACAAACCGAAGCGACTATAAGAAACCTACGACAACAAGATGCAATTAAAGAGGAGATGTCTGCTGATAACATTAAAGTCGAACTTTCACACTTGCAAATCATCAACGATAACTACTTGGAGATCAATAAGGATGTGCCTGTATGTATAGAGGAACCTTCAAAAACAGAactgtattattgctacaactgcaatTTCAATACTCACAAAAAGACTATTTTGATTCGACACTTGATTCACGAGAATGTAAAAGTTACTGGTAGAAAACggtttaaatgcagtatatgtgattactacACTATTAGCAGGTCGCATTTAAAAGTCCATgtacgtaagcacactggtgaaaaaccatttaaatgcaatgtatgtgattacgGTAGTAGCCAAATTggaaatttaaaatcacatatgcgtaagcacactggtgaaaaaccatttaaatgcaatgtatgtgattactgtagtagccAAATTGGAagtttaaaagcacatatgcgtaagcattctggtgaaaaaccatttaaatgcaatgtatgtgattactgtagtagccAAATTGGAagtttaaaagcacatatgcgtaagcattctggtgaaaaaccatttaaatgcaatgtatgtgattactgtagtagccAAATTGGAagtttaaaagcacatatgcgtaagcattctggtgaaaaaccatttaaatgcaatgtatgtgattactgtagtagccAAATTGGAagtttaaaagcacatatgcgtaagcattctggtgaaaaaccatttaaatgcaatgtatgtgattactgtagtagccAAATTGGAagtttaaaagcacatatgcgtaagcattctggtgaaaaaccatttaaatgcaatgtatgtgattactgtagtagccAAATTGGAagtttaaaagcacatatgcgtaagcacactggtgaaaaaccatttaaatgcaatgtatgtgattactgtagtagccAAATTGGAagtttaaaagcacatatgcgtaagcacggtggtgaaaaaccatttaaatgcaatatatgtgattactgtggTGCCCAATTGGcacatttaaaaaggcatatgcttaAGCACACTCGTGTGATTACTGCAGCAGCCAGTTGGAATACTGGTAAATAA
Protein Sequence
MGERSTKICRICSLEIIEVEPYYFLNNDTNSMLQFKLLKLLPEIDLNITTNPIACKRCMIAIKEIYEFKQLCIQTEATIRNLRQQDAIKEEMSADNIKVELSHLQIINDNYLEINKDVPVCIEEPSKTELYYCYNCNFNTHKKTILIRHLIHENVKVTGRKRFKCSICDYYTISRSHLKVHVRKHTGEKPFKCNVCDYGSSQIGNLKSHMRKHTGEKPFKCNVCDYCSSQIGSLKAHMRKHSGEKPFKCNVCDYCSSQIGSLKAHMRKHSGEKPFKCNVCDYCSSQIGSLKAHMRKHSGEKPFKCNVCDYCSSQIGSLKAHMRKHSGEKPFKCNVCDYCSSQIGSLKAHMRKHSGEKPFKCNVCDYCSSQIGSLKAHMRKHTGEKPFKCNVCDYCSSQIGSLKAHMRKHGGEKPFKCNICDYCGAQLAHLKRHMLKHTRVITAAASWNTGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-