Basic Information

Insect
Aquatica leii
Gene Symbol
-
Assembly
GCA_035610365.1
Location
CM069435.1:105755683-105757450[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.12 29 8.0 1.5 1 20 124 143 124 145 0.95
2 11 2.4e-06 0.00057 22.8 5.1 1 23 185 207 185 207 0.98
3 11 3e-05 0.0071 19.4 5.8 1 23 213 235 213 235 0.99
4 11 0.00078 0.19 14.9 4.8 1 23 241 263 241 263 0.99
5 11 1.6e-07 3.7e-05 26.5 1.2 1 23 269 291 269 291 0.99
6 11 4.8e-06 0.0011 21.9 3.3 1 23 297 319 297 319 0.99
7 11 1.7e-06 0.00042 23.2 3.7 1 23 325 347 325 347 0.99
8 11 4.9e-06 0.0012 21.8 5.0 1 23 353 375 353 375 0.99
9 11 7.9e-05 0.019 18.0 1.7 1 23 381 403 381 403 0.99
10 11 7.9e-05 0.019 18.0 1.7 1 23 409 431 409 431 0.99
11 11 9.4e-05 0.023 17.8 1.7 2 23 438 459 437 459 0.96

Sequence Information

Coding Sequence
ATGGaggaaaaaacaacaaatgtttgtcggatttgtttactagaaatagtagaaaccgaGCAGTATTATTTTCTGGACAACAATGAGCTATTGCTACAATCAAAGTTGTTGTACCTTTtaccagaaattgatctaaatATCACATCGAACCCAGTTGTTTGTAACGGATGTATGATTACAATTGAAGAAATCTACGAATTTAAACAACTGTGTATACAAACTGAAACTACTATAGGGAacttacaacaacaaaaagtaatcaaaGAAGAGTCCTTTGACGTTGAAGACTTGCAAATCACTAGCGATGACTGTTTGGAAATCAAACCAGAGGTGACTGTATGTGCCGAAGAACCTTCAAAAGCAGaattgtattattgctacaactgtgACTTTAACACTAATAAGAAGATGAATTTGATTCAACACCTAATTCATGAAAAGCTAAATGCTGATATGCATAAAGACATAAACGTGAAATTTTATTGCAGTACcaacaaCCGTGACTCAAgatgtttaaaaattcatatgtataagcacactggtgaaaaaccatttaaatgcaatatttgtgattactgcagtaccaacaagtcaaatttaaaaaagcatataagTAAGCACACTATcgaaaaaccatttcaatgtaatatatgtgattactgcagtatcaCTATGTCGCATTTAAAAAgccatatgcgtaagcacactggcgaaaaaccatttcaatgcaatACTTGTGTTTATTCTAGCAGCCAatcgaaatgtttaaaaattcatatgcgtaagcacactggtgaaaaaccatataaatgcaatatttgtgattatgGCAGTACCGATAAgtcgaatttaaaaattcatatgcgtaagcatactggtgaaaaaccatttaaatgcaatatttgtgattactgcagtacgaCTAAGTTGGGTTTAGAGAGGCATATGCGtacacacactggtgaaaaaccatttcaatgcaaCATTTGTAATTACTCATGTAGTCAATCaggatatttaaaaattcatatgcgtaagcacactggcgaaaaaccatttcaatgcaaCATTTGTAATTACTCGTGCAGTCAATcacgatatttaaaaattcatatgcgtaagcacactggcgaaaaaccatttcaatgcaatACTTGTGTTTATTCTAGCAGCCAATCTAAaggtttaaaaattcatatgcgtaagcacactggcgaaaaaccatttcaatgcaatACTTGTGTTTATTCTAGCAGCCAATCGAAaggtttaaaaattcatatgcgtaagcacactggcaAAAAACCATTATATTGCAATATCTGTGATTACTCTTGCAGTCAAGTGGGAAGTTTAAAAAAGCATGTACGtcagcatactggtgaaaaatga
Protein Sequence
MEEKTTNVCRICLLEIVETEQYYFLDNNELLLQSKLLYLLPEIDLNITSNPVVCNGCMITIEEIYEFKQLCIQTETTIGNLQQQKVIKEESFDVEDLQITSDDCLEIKPEVTVCAEEPSKAELYYCYNCDFNTNKKMNLIQHLIHEKLNADMHKDINVKFYCSTNNRDSRCLKIHMYKHTGEKPFKCNICDYCSTNKSNLKKHISKHTIEKPFQCNICDYCSITMSHLKSHMRKHTGEKPFQCNTCVYSSSQSKCLKIHMRKHTGEKPYKCNICDYGSTDKSNLKIHMRKHTGEKPFKCNICDYCSTTKLGLERHMRTHTGEKPFQCNICNYSCSQSGYLKIHMRKHTGEKPFQCNICNYSCSQSRYLKIHMRKHTGEKPFQCNTCVYSSSQSKGLKIHMRKHTGEKPFQCNTCVYSSSQSKGLKIHMRKHTGKKPLYCNICDYSCSQVGSLKKHVRQHTGEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00153919;
90% Identity
-
80% Identity
-