Basic Information

Gene Symbol
-
Assembly
GCA_949987775.1
Location
OX465244.1:6270973-6287603[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00015 0.02 16.7 0.7 2 23 121 143 120 143 0.94
2 8 0.00024 0.034 16.0 4.0 1 23 172 195 172 195 0.96
3 8 0.00023 0.031 16.1 2.0 1 23 201 223 201 223 0.98
4 8 0.032 4.4 9.4 2.6 1 23 251 273 251 273 0.92
5 8 0.64 89 5.3 0.0 1 20 324 343 324 345 0.91
6 8 1.8 2.5e+02 3.8 1.4 1 19 361 379 361 383 0.92
7 8 5e-06 0.0007 21.3 3.1 1 23 603 626 603 626 0.97
8 8 0.021 2.9 9.9 0.2 2 21 633 652 632 653 0.92

Sequence Information

Coding Sequence
ATGAGCGATCGCAATGGAAAGAGTAGCAATTCGAGTGTTACAGGAAGTGATTTGGAGGGTGTTGAGGATTCGTATATTGCTGGGAGCAGTCAAGGTGCCGCGTTTGAAAGTCTTCGAGGCTTCCAGAAGAAGCCAGCTGTGTTAGTTGAGCGCCTCGACCTAAGCCCATTCACGGCACAGAACACACGAACCGCAGTTgttaacaacaacaacaactcCTCATTCAGTAAACCCCAAGTTCCAACTGACAAATTTCATGCACAGTGTTGCGTCAATTTAGTTAGCTATGACCTAAAGAAGCtaaaagttttatataaaaaaaagtcaaatataCCGATAATTGAAATGGATGCAAACAtaaaatgcaaaatatgtggGAAAATTTATTCTAGTGAGAGAAAATTGTTGAATCACCAAGAAAATAAGCATATGATTGTGTACCGACCGAAACCCAAGTCCAAGAAACGCGTGTCGTTTTCTGATAAAGTCATTATACATGAGGTCACTGAGTACCACAAGTGCCGGAAATGTCCGAAGATATTTGAAAGCTACAAGTCTTTGAAAAGTCACATGAAAGAGCAGCAcaagaaaagaaaatgttataTCTGCAACTATTGTTCAAAGAAATTTGTAGACCGGATGTTCTTTAAAGTCCACATAAAACTGCATTGTGAAGCATGTGGGCTACTATTATCCAACAGAACACGGTTCCTAGAACACAAACGCTTAGTTTGCAAAACATCAAAACTTTACAAATGCAAGACTTGTGACATTACATTCTTCAAATTCATGGATTTGAAAGACCACAGCTATGAACACATAAGTACATGTTATGTCTGTGACATATGCAAAGACCAATGTGTGACGAAATGTGCTGTGTCTCATCATATTTACTTCTTACACACAACAAAACGCCGAAAACGCAGTCCAGAGTTGTACCTTACACGGAAACTAGGTAGCGAGAGCTTATACCTTTGCAAGTTTTGTGAAGAAAGCTCAGTAGATAAAGACTTGATTGAGAAACACGTTGAGGTATTACCAGATTTGACAAACAGGGCTATGACTGGCTACAAAGACTATTATTTTTGCGATCAATGTATGAAAAAGTTTGATACAGAGAAAGATATGCTGCAACATAAGTGGAGTCACTTCTTAAAGACGCCTGACAACTCTCAGATTCGACCAAAAAGCATCCTTCTATCAATCCTTACAAATAACATGCCAACAAAGACTTTTTACAATGTTAATGGAAATATTCCAGACCATTTTAAACCTAAAGTGGTTGTAGAGAGGATGGAAATTGATAAAATATCCAAGATTGGGGCAGAAACACCAACCACTGTCCAGAGTGCTGAAGCTTCTCCAGACACAACACAGaatacagaaataaataatgcaGAAACAAAGAATGTAGAAGCAATTGATGCAGAAGCAACTGATGCAGAAGCAATGAATGCTGAAACAGTAAATACTGTAACAAATAATGCTGAAACAGTAAATACTGTAACAAATAATGCTGAAACAGTAAATACTGTAACAAATAATGCTGAAACAGTAAATACTGTAACAAATAATGCTGAAACAGTAAATACTGTAACAAATAATGCTGAAACAGTAAATACTGTAACAAATAATGCTGAAACAGTAAATACTGTAACAAATAATACTGAAACAGTAAATACTGTAACAAATCATGCTGAATCGATAATTACTGTACCAAATAATGCAGCAACGAAAAAAGCAGCAACAAAGAAATCGGAAAACAAGAAAGCTTTGATAGTTTCAAGGAGAACTATCATCTCAAACCACCAATGTCAGACCTGCGGCAAATACTTCTCGTCGAACCAAAGTCTAAACCGCCATATTGAGACCCAACACTTCGATTTTGAGAACCTTCGCTGCAAGGTCTGCGAAGAAGTCTTCGCGTGGCCATCACTACTCCAAAGACACAAGTGCATTCGCTTGGAGATCCCAGAAATGTCCTTTGAGGATGCCCGACCAGAAATTCACTTCACAAATTACAGTCCGATTCAGAATAATGCTTCTGTGCTACAAGAAACTTTGAACCATGACGTCAACGGATTTGATGACTTACCAATAGTTAATTACGACAATTACTCTGTAGATTTCGAAATACCAGCTCCTATCGTGGGAGTGAACGATATGAGCAGTTCGTCTGTGCCTAACCAAGTGTTGAATCAAAGTGATAATGAAAAGTTGTTGCCGTTAAAAAGTTTGGGTTATGAAGTCATGCAGGTAGTACCGATTGAGTACtga
Protein Sequence
MSDRNGKSSNSSVTGSDLEGVEDSYIAGSSQGAAFESLRGFQKKPAVLVERLDLSPFTAQNTRTAVVNNNNNSSFSKPQVPTDKFHAQCCVNLVSYDLKKLKVLYKKKSNIPIIEMDANIKCKICGKIYSSERKLLNHQENKHMIVYRPKPKSKKRVSFSDKVIIHEVTEYHKCRKCPKIFESYKSLKSHMKEQHKKRKCYICNYCSKKFVDRMFFKVHIKLHCEACGLLLSNRTRFLEHKRLVCKTSKLYKCKTCDITFFKFMDLKDHSYEHISTCYVCDICKDQCVTKCAVSHHIYFLHTTKRRKRSPELYLTRKLGSESLYLCKFCEESSVDKDLIEKHVEVLPDLTNRAMTGYKDYYFCDQCMKKFDTEKDMLQHKWSHFLKTPDNSQIRPKSILLSILTNNMPTKTFYNVNGNIPDHFKPKVVVERMEIDKISKIGAETPTTVQSAEASPDTTQNTEINNAETKNVEAIDAEATDAEAMNAETVNTVTNNAETVNTVTNNAETVNTVTNNAETVNTVTNNAETVNTVTNNAETVNTVTNNAETVNTVTNNTETVNTVTNHAESIITVPNNAATKKAATKKSENKKALIVSRRTIISNHQCQTCGKYFSSNQSLNRHIETQHFDFENLRCKVCEEVFAWPSLLQRHKCIRLEIPEMSFEDARPEIHFTNYSPIQNNASVLQETLNHDVNGFDDLPIVNYDNYSVDFEIPAPIVGVNDMSSSSVPNQVLNQSDNEKLLPLKSLGYEVMQVVPIEY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-