Basic Information

Gene Symbol
-
Assembly
GCA_905147355.1
Location
LR990305.1:10247084-10258447[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00028 0.032 16.3 0.8 1 23 551 573 551 573 0.97
2 13 0.0027 0.31 13.2 0.6 1 23 578 601 578 601 0.96
3 13 0.036 4.1 9.7 0.2 1 13 612 624 612 628 0.87
4 13 0.036 4.1 9.7 0.2 1 13 647 659 647 663 0.87
5 13 0.036 4.1 9.7 0.2 1 13 682 694 682 698 0.87
6 13 0.036 4.1 9.7 0.2 1 13 717 729 717 733 0.87
7 13 0.036 4.1 9.7 0.2 1 13 752 764 752 768 0.87
8 13 0.23 26 7.2 0.1 1 12 787 798 787 803 0.88
9 13 0.041 4.6 9.5 0.1 1 12 983 994 983 999 0.88
10 13 0.018 2 10.7 0.4 1 14 1017 1030 1017 1033 0.86
11 13 0.036 4.1 9.7 0.2 1 13 1044 1056 1044 1060 0.87
12 13 1.7e-05 0.0019 20.2 0.6 1 23 1079 1101 1079 1101 0.98
13 13 0.0059 0.67 12.2 0.4 1 23 1107 1130 1107 1130 0.95

Sequence Information

Coding Sequence
ATGGTTCGAAGCTTAGGTCCTCCAACATGGTTTTTGTCATTTTCCTGCAATGACCTTAATTGGCCAGACATGACCAAAGCGCTGTTAATCGCCGATGGACGCGACATCAATGCCGCTGAGCACCTGACATTCCCGGAACGCATGGAATTAGTGCAACGATATCCGGTAGTAGTAGCACGACAGTTTACGCTGCGTGTAAACGGTCTCATGCGATTCTTAAAGCATAACGACGATTGCTTGGGTGGCCCTATTGAAGACTTTTGGTACCGAGTGGAGTTCCAAAATCGCGGTAGTCCACATCTGCACATGTTGTTGTGGTGTAGCAATATCCCGGAGTTATCTAGTCCACAAGGAATAGAAGTAATTGAAAAAGTGGATGATGGTTGTCGCTTTGGTTTTGCAAAGCCAGCGAGCGAAAGAACCGTTTGCTTGGGCGCAGATGAAGCACTTGCGAACAATGGACGATTTTGTTTATTGAAAAGAAGCTCCGAAGAAAGTATGAGACAAGGTGGTGATGTTTGGCAACAATTATTTTCGGTATCAATGGTTATTTTAAATCAACGCTTGGTGAGTGCGCCAGAATGCGCATACCGATTATGTCACCTACCATTCAAAATGTCATCGCGAAAAAccgttttcgtaaataactgtAAGCCGGAGGAGCGTTTCAGGCTTTTGAGATTTGACAGTGATGAAACCAGTATTTACAACAACATCTTTGATCGTTATGTGATCCGTCCACATGAACTGGAGGATTTGAGCCTTGCTGAATTTGCTGTCCGATTTGAGACTATTTCTAATACCTTGTGGTCGGAGGATGAGGGTGATGCCGAATTGAGGGATGAAGATACTACACCGGAGCGATATATCAGATTGCAAGACAACACGAAAATGCATATAAGAAACAAGCCAGCAGTACTACGCACCCGCTATTATACTGTTAATAGCGACAAGGAAGCCTATTATTATAGTCTAATAGTGTGCCACATTCCATTCCGTGATGAAGGCGAGTTATTGCTCGAAGATGAGACCGCAGAGGACTGTTTCGTAAGACGCCAAGCAGATTTTCGCCCGTTGCAAGCTAACGTCAGCGCAGAACAATTTGCTCATGCTGAGCAAATTATTCAACAGGCTCTTGCACAAGTAACAGCCCTTAATGCTGCGCGCGAAACCCATATCGACACTGATCCCACCTTATGCGTTGGTGAAAATATCGTAAACGGCGATGACTCTTATTGTGAGGACGTTGGAGAACGAGCAGTGATGTCCGATGAATTGTTCCTAGGCAGCATTCGGGGATTAAATATTCAGCAGAGGAACTTATTTCAGAATGTTTCCACAGCGGTCGAAAATGATTTGCACGGCATAGAAAGTCAGCTACTACTGTTTATTACGGGTGGTGCAGGTAGCGGTAAATCGTTTCTTCTGAAATTGATCGTGGAGCATGTAAAACGTTGCTACGCACCAACTGTCGAAGCACTGCTGAAACCTAACTTTGTTGAGGTTGGGTCATTGACTGGGGTTGCTGCTCGTCAAATATTTGGCAGAACACTTCATAGTATTTTCTTTCTCCCGATTGAGAAAGGAAATACTATGACGTACAAAAAACTGACTGGACAAAGACTCGAGAACGAACGACGTAAATGGCGATTCGAATGCGATTATTGCGGCAGAAAGTTCTTGAATCTCGGCTTGCTCCGGAAGCATATGGACTACCACAGCGACACCCTGTACCCGTGCCAGCAGTGCCCAAAGGTATACAAGACGCGGATAGCTCGCAAAGTGCACATCAAAAATAAGCACGAGGGCGAGGCGGAGCGGAGGGGGCGGGACTTCGTGTGCGACTACTGCGGGAAGGCGTTCACTGTGAGTATTAACCGCATGGCCAGGACACTGTCTACTATATGTGCACGAGGGGAGGGGCCGAGGGGGCGGGACTTCGTGTGTGACTACTGCGGGAAGGCGTTCACTGTGAGTATTAACCGCATGGCCAGGACACTGTCTACTATATGTGCACGAGGGGAGGGGCCGAGGGGGCGGGACTTCGTGTGTGACTACTGCGGGAAGGCGTTCACTGTGAGTATTAACCGCATGGCCAGGACACTGTCTACTATATGTGCACGAGGGGAGGGGCCGAGGGGGCGGGACTTCGTGTGTGACTACTGCGGGAAGGCGTTCACTGTGAGTATTAACCGCATGGCCAGGACACTGCCTACTATATGTGCACGAGGGGAGGGGCCGAGGGGGCGGGACTTCGTGTGTGACTACTGCGGGAAGGCGTTCACTGTGAGTATTAACCGCATGGCCAGGACACTGCCTACTATATGTGCACGAGGGGAGGGGCGGAGGGGGCGGGACTTCGTGTGCGACTACTGCGGGACGGCGTTCACTGTGAGTAACCGCATGGCCAGGACACTGTCTACACTCACGAGCAAAGAAACGGAATCACTTCACATTTTTCGTGAAAAGTGCCTGAAGGGAATTCATACCACGGAAGTTGAAGCCGCCCAAGTTGTGACTTTGCTGGAGCGTGGTGATAGTCAACGCTCCGTTGCCGCCCAGCTGAATTTGGGCGAGTCCACGGTTTCCAAAGTTTGTCGGTGGTTTCAAGAAACTGGAAGCCTCATTCCGAGACCAGGAACCGGCTGCCAGAGGGAAACTGTCGCCTACGGACCCTACGGTGGAGGGTCAGTCATGTGGTGGGCGGGCATTTCAtacgacggacggacggagctTGTTTTCGTGCCTGGTGGAGGTCGAGGTGGCGGTTTGAGGAAGAAAAGATACATCTTGGACATCCTGGAAGAGCATGTGGTACCGTACGCAAATTATTTTAACGAGGGGTTCCATCTGGAGCAAGACAATGCTCCTTGTCACACCGCGGGGGACACCCTGAGGACACTGCCTACTATATGTGCACGAGGGGAGGGGCGGAGGGGGCGGGACTTCGTGTGCGACTACTGCGGGAAGGCGTTCTCTGTGAGTAACCGCATGGCCAGGACACTGCCTACTATATGTGCACGAGGGGAGGGGCGGAGGGGGCGGGACTTCGTGTGCGATTACTGCGGGAAGGCGTTCACTGACACTGCCTACTATATGTGCACGAGGGGAGGGCCGAGGGGGCGGGACTTCGTGTGCGACTACTGCGGGAAGGCGTTCACTGTGAGTATTAACCGCATGGCCAGGACACTGTCTACTATATGTGCACGAGGGGAGGGGTCGAGGGGGCGGGACTTCGTGTGCGACTACTGCGGGAAGGCGTTCACTACAAAACAAATTCTCCTACAACACATGAACTCGCACACGGGCGAGCGGCCGTACGCGTGCAAGTTGTGCGGCGCCACGTTCGGGTTCAAGAGCGCCCTCTACCTGCACGGGCGGTACAAGCACAAGATACAGAAGAAAAACCAGGACGCGAATAAAATCGAGGACGCGAAGAAAATCGGGGACGCGATAGACAAATCAAAATAA
Protein Sequence
MVRSLGPPTWFLSFSCNDLNWPDMTKALLIADGRDINAAEHLTFPERMELVQRYPVVVARQFTLRVNGLMRFLKHNDDCLGGPIEDFWYRVEFQNRGSPHLHMLLWCSNIPELSSPQGIEVIEKVDDGCRFGFAKPASERTVCLGADEALANNGRFCLLKRSSEESMRQGGDVWQQLFSVSMVILNQRLVSAPECAYRLCHLPFKMSSRKTVFVNNCKPEERFRLLRFDSDETSIYNNIFDRYVIRPHELEDLSLAEFAVRFETISNTLWSEDEGDAELRDEDTTPERYIRLQDNTKMHIRNKPAVLRTRYYTVNSDKEAYYYSLIVCHIPFRDEGELLLEDETAEDCFVRRQADFRPLQANVSAEQFAHAEQIIQQALAQVTALNAARETHIDTDPTLCVGENIVNGDDSYCEDVGERAVMSDELFLGSIRGLNIQQRNLFQNVSTAVENDLHGIESQLLLFITGGAGSGKSFLLKLIVEHVKRCYAPTVEALLKPNFVEVGSLTGVAARQIFGRTLHSIFFLPIEKGNTMTYKKLTGQRLENERRKWRFECDYCGRKFLNLGLLRKHMDYHSDTLYPCQQCPKVYKTRIARKVHIKNKHEGEAERRGRDFVCDYCGKAFTVSINRMARTLSTICARGEGPRGRDFVCDYCGKAFTVSINRMARTLSTICARGEGPRGRDFVCDYCGKAFTVSINRMARTLSTICARGEGPRGRDFVCDYCGKAFTVSINRMARTLPTICARGEGPRGRDFVCDYCGKAFTVSINRMARTLPTICARGEGRRGRDFVCDYCGTAFTVSNRMARTLSTLTSKETESLHIFREKCLKGIHTTEVEAAQVVTLLERGDSQRSVAAQLNLGESTVSKVCRWFQETGSLIPRPGTGCQRETVAYGPYGGGSVMWWAGISYDGRTELVFVPGGGRGGGLRKKRYILDILEEHVVPYANYFNEGFHLEQDNAPCHTAGDTLRTLPTICARGEGRRGRDFVCDYCGKAFSVSNRMARTLPTICARGEGRRGRDFVCDYCGKAFTDTAYYMCTRGGPRGRDFVCDYCGKAFTVSINRMARTLSTICARGEGSRGRDFVCDYCGKAFTTKQILLQHMNSHTGERPYACKLCGATFGFKSALYLHGRYKHKIQKKNQDANKIEDAKKIGDAIDKSK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-