Basic Information

Gene Symbol
-
Assembly
GCA_905147355.1
Location
LR990305.1:944939-946573[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 3.6e-05 0.004 19.2 1.0 2 23 86 108 85 108 0.94
2 14 0.00071 0.081 15.1 2.8 2 23 116 138 115 138 0.95
3 14 0.0039 0.43 12.7 2.0 2 23 145 167 144 167 0.92
4 14 3.8e-07 4.3e-05 25.4 1.2 3 23 176 197 174 197 0.95
5 14 4.6e-05 0.0052 18.8 1.2 2 23 205 227 204 227 0.96
6 14 0.00014 0.016 17.3 0.8 1 23 234 257 234 257 0.97
7 14 0.024 2.7 10.3 3.0 3 23 265 286 264 286 0.94
8 14 0.0013 0.15 14.2 0.8 2 23 302 324 301 324 0.93
9 14 4.8e-05 0.0054 18.8 0.1 3 23 333 354 332 354 0.96
10 14 5.2e-07 5.8e-05 24.9 2.5 2 23 360 382 360 382 0.96
11 14 0.01 1.2 11.4 3.6 3 23 391 412 389 412 0.94
12 14 2.9e-05 0.0033 19.4 3.4 1 23 418 440 418 440 0.98
13 14 1.1 1.2e+02 5.0 1.5 1 23 446 469 446 469 0.92
14 14 0.1 12 8.2 0.9 2 21 506 525 505 526 0.92

Sequence Information

Coding Sequence
ATGGAGCCAGACATAGAGCAGATCTTCATAAAACCAGACATTGCACACTTGAAGGTAGAAGTCAATTGTGAACAGGAACAGAGTGGGAACCCGTACCAGTCCCCCGACGATGTCTTCGATATCAAGAGAAGCGACATCACCGTGCATATCCGACCGTATGAAGACTCTGCCTCCAATGACTATGAAAATGCTCCGAAAACCGATTCCGTTGAAATTGTCGGTAAAGTATACGAAAATGGCAAAGTGAATAGACTCCAGTGTCCACAGTGTGATAATAACTTTAAAAACAGAGCCAATTTGAAGCAACACTTGAAGTTCGTGCACTCATCAGAAGATGATATCGTAGAGTGTGACAAATGCTACAGAACTTTTAAATCTGTGGGTCACTTGCGGTCTCACATCCATTCGGTTCATGCGGAAGAGAAGGAGGTGAGTTGTGAGCATTGCGGCAAGGTTTTCTTGAACAAAAAGCGTCTAAACAACCATATATTCTATTCGCATCCCGAACCAGAAGAAAGTGTCAATTGTACTGTATGTTCCAAATCTTTTAAACGGAGATACAACTTGAAAATTCATATGAGACTTGTCCATCCGTCAGAAGACAGGTCCGTGCAATGCCCGCATTGTGATAAAAAGTTCAAAGTAGACATGTTGCTGCAGAGACATATTAAATGGAGCCACCCGCAAGACGGGATGATGTACCGCTGTCCGGAGTGCGGCCGGACGCTGCCTTCCATCGCTTGCTTCCGGAAACACATGCAGAACGTCCACTCGGAGTCCCAAGACGCCATTTGTAAAATCTGCTGTAAGGTTTTTAAAACTGTAAAAACTTTAAAGCGTCACGAGAACAATATACATGGGGACGGGAAAGTAGAAGTGAAACAGTATAAAGTTGGCGACCTGCCTTGTTCACAATGTGAAAGGAAGTTCACCACCAACACAGCTCTGTTTTGGCATTTCGAGAGATACCATTCTGAGAATAAAAGGAGCAACGCTTGTCAGATTTGTGGGAAAGAGCTTTCAGACCAAGGCAGTTTGAAAAGGCATTTAGAGATGGTGCATTCCGTAGAGCCGGCTAGCTGCCATATATGCTCGAAGACTTTTAAAAGCCCCATGAACCTGCAGAGACATATTAGAGTGACGCACGCGCCCCCCGAGGCCGCACAGAACTGCGACATTTGTAAGAAAACCTTTAAATGCTCGATGCATTTGCGTATTCACATCAACGCTGTACATTCTACAGAAGGGATTTTCAGCTGTGATATTTGTAATAAAGATTTCTCTTCCAAGAAATACATGTTGAAACACAGGAAGACTCACGTGGATGTGAAAGAGTTCCCGTGCGGCGTTTGCAACAAGTTGTTTAAATGCGTGAATGATGTTAAGAAACATGCCAAACGCGTGCATATGAAGGCTCAAGTGAAAACAGAAAACGAGGAGATCGGTACAGATTATTCTGAAGATGCATCTAAGAGCACCGAGTCGATCGATGAAGTTGGGACCTCGGAGTCACTGAACTGCTTCAAATGTGGCTGTGATTTTATGAGCGCTGCCGAATTGCACTCTCATATATTGAACTGTAGCGATGTCCCGTTAACTTCGTTTGTTAAGGTTGAAATGCAAGATGAGACGTAG
Protein Sequence
MEPDIEQIFIKPDIAHLKVEVNCEQEQSGNPYQSPDDVFDIKRSDITVHIRPYEDSASNDYENAPKTDSVEIVGKVYENGKVNRLQCPQCDNNFKNRANLKQHLKFVHSSEDDIVECDKCYRTFKSVGHLRSHIHSVHAEEKEVSCEHCGKVFLNKKRLNNHIFYSHPEPEESVNCTVCSKSFKRRYNLKIHMRLVHPSEDRSVQCPHCDKKFKVDMLLQRHIKWSHPQDGMMYRCPECGRTLPSIACFRKHMQNVHSESQDAICKICCKVFKTVKTLKRHENNIHGDGKVEVKQYKVGDLPCSQCERKFTTNTALFWHFERYHSENKRSNACQICGKELSDQGSLKRHLEMVHSVEPASCHICSKTFKSPMNLQRHIRVTHAPPEAAQNCDICKKTFKCSMHLRIHINAVHSTEGIFSCDICNKDFSSKKYMLKHRKTHVDVKEFPCGVCNKLFKCVNDVKKHAKRVHMKAQVKTENEEIGTDYSEDASKSTESIDEVGTSESLNCFKCGCDFMSAAELHSHILNCSDVPLTSFVKVEMQDET*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00148678;
90% Identity
iTF_00148678;
80% Identity
-