Basic Information

Insect: Apotomis turbidana
Gene Symbol: ESRRB
Assembly: GCA_905147355.1
Location: LR990298.1:2882317-2893538[+]

Transcription Factor Domain

TF Family: NGFIB-like
Domain: zf-C4|NGFIB-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: During the development of the vertebrate nervous system, many neurons become redundant (because they have died, failed to connect to target cells, etc.) and are eliminated. At the same time, developing neurons send out axon outgrowths that contact their target cells [1]. Such cells control their degree of innervation (the number of axon connections) by the secretion of various specific neurotrophic factors that are essential for neuron survival. One of these is nerve growth factor (NGF), which is involved in the survival of some classes of embryonic neuron (e.g., peripheral sympathetic neurons) [1]. NGF is mostly found outside the central nervous system (CNS), but slight traces have been detected in adult CNS tissues, although a physiological role for this is unknown [1]; it has also been found in several snake venoms [2, 3]. Proteins similar to NGF include brain-derived neurotrophic factor (BDNF) and neurotrophins 3 to 7, all of which demonstrate neuron survival and outgrowth activities. Although NGF was originally identified in snake venom, its most abundant and best studied source is the submaxillary gland of adult male mice [4]. Mouse NGF is a high molecular weight hexamer, composed of 2 subunits each of alpha, beta and gamma polypeptides. The beta subunit (NGF-beta) is responsible for the physiological activity of the complex [4].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0031 45 5.0 0.0 72 98 234 260 218 261 0.79

2 18 0.003 45 5.0 0.0 72 98 301 327 281 328 0.80

3 18 0.003 45 5.0 0.0 72 98 368 394 348 395 0.80

4 18 0.003 45 5.0 0.0 72 98 435 461 415 462 0.80

5 18 0.003 45 5.0 0.0 72 98 502 528 482 529 0.80

6 18 0.003 45 5.0 0.0 72 98 569 595 549 596 0.80

7 18 0.003 45 5.0 0.0 72 98 636 662 616 663 0.80

8 18 0.003 45 5.0 0.0 72 98 703 729 683 730 0.80

9 18 0.003 45 5.0 0.0 72 98 770 796 750 797 0.80

10 18 0.003 45 5.0 0.0 72 98 837 863 817 864 0.80

11 18 0.003 45 5.0 0.0 72 98 904 930 884 931 0.80

12 18 0.003 45 5.0 0.0 72 98 971 997 951 998 0.80

13 18 0.003 45 5.0 0.0 72 98 1038 1064 1018 1065 0.80

14 18 0.003 45 5.0 0.0 72 98 1105 1131 1085 1132 0.80

15 18 0.003 45 5.0 0.0 72 98 1172 1198 1152 1199 0.80

16 18 0.003 45 5.0 0.0 72 98 1239 1265 1219 1266 0.80

17 18 0.003 45 5.0 0.0 72 98 1306 1332 1286 1333 0.80

18 18 0.003 44 5.0 0.0 71 98 1372 1399 1353 1400 0.80

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0031	45	5.0	72	98	234	260	218	261	0.79
2	18	0.003	45	5.0	72	98	301	327	281	328	0.80
3	18	0.003	45	5.0	72	98	368	394	348	395	0.80
4	18	0.003	45	5.0	72	98	435	461	415	462	0.80
5	18	0.003	45	5.0	72	98	502	528	482	529	0.80
6	18	0.003	45	5.0	72	98	569	595	549	596	0.80
7	18	0.003	45	5.0	72	98	636	662	616	663	0.80
8	18	0.003	45	5.0	72	98	703	729	683	730	0.80
9	18	0.003	45	5.0	72	98	770	796	750	797	0.80
10	18	0.003	45	5.0	72	98	837	863	817	864	0.80
11	18	0.003	45	5.0	72	98	904	930	884	931	0.80
12	18	0.003	45	5.0	72	98	971	997	951	998	0.80
13	18	0.003	45	5.0	72	98	1038	1064	1018	1065	0.80
14	18	0.003	45	5.0	72	98	1105	1131	1085	1132	0.80
15	18	0.003	45	5.0	72	98	1172	1198	1152	1199	0.80
16	18	0.003	45	5.0	72	98	1239	1265	1219	1266	0.80
17	18	0.003	45	5.0	72	98	1306	1332	1286	1333	0.80
18	18	0.003	44	5.0	71	98	1372	1399	1353	1400	0.80

Sequence Information

Coding Sequence: ATGATGTCGGCGGTGAGCGGCACGGGCGACCAGCTGCTACGGCGCGTGAAGCAGGAGGCTGAGCCTCCGCCACAGTACTCGCCCACTGAACAGCTGACCCTGGCTTCGCCGCATCCACGCCCTATGCTTCTACAACCAGAGATGGAACTAGAGCCCAAAGAAGAGGTGAAGTTCTGCGTGTCCCCCGGCGAAGGGATCGTCGGCAACACCAGCCCGGAACAGCAGCACTGCTCGTCCACGACTGCCGCAGCCCCCAGCGCGCGAGATGACGACACGCCGAGGAGACTGTGTCTTGTGTGCGGGGACGTGGCGTCTGGCTTCCATTACGGAGTGGCCAGCTGTGAGGCCTGCAAGGCGTTCTTCAAGAGGACGATCCAGGGCAACATAGAATACACCTGTCCGGCGTCAAACGAATGCGAGATCAACAAACGGCGACGCAAGGCGTGCCAAGCGTGCCGCTTCAGAAAATGCCTGCGCACGGGCATGCTCCGCGAGGGCGTGCGTCTGGACAGAGTGCGCGGCGGCAGGCAGAAGTACAGACGCGCGCCCGaccagccgccgcccgcgccgcgcccgcaCCTCGACGACATTaagATTCTGGAAGTGCTATCATCGTATGAACCAGAGCCGTTGGCTTGCGGCACGGTGCCGGCCGGCGTGACCGAGCCCACGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTACCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTACCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTACCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTACCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTACCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTACCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCAAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTAAGACCGCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGCTGCTGGCCGACCTGTACGACCGCGAGCTGGTGGGCGTCATCAGCTGGGCCAAGCAGATACCCGGCTTCACGGACTTGCAGCTTAATGACCAGGTAAGGCCTCACACTTGGTGCCCGAGCCCGCGGCGAGGACGCTGGCGTTTCTGGCTGACTTGTATGATCGTGAAGCTGCAGTTTAATGGCCAGTTTGGTGCTAATCTATCATCACCAGGAGGTCTATCTAGAGGTGTAGCGTCAAAAAAATATCTGGGCGAACCGGTATAG
Protein Sequence: MMSAVSGTGDQLLRRVKQEAEPPPQYSPTEQLTLASPHPRPMLLQPEMELEPKEEVKFCVSPGEGIVGNTSPEQQHCSSTTAAAPSARDDDTPRRLCLVCGDVASGFHYGVASCEACKAFFKRTIQGNIEYTCPASNECEINKRRRKACQACRFRKCLRTGMLREGVRLDRVRGGRQKYRRAPDQPPPAPRPHLDDIKILEVLSSYEPEPLACGTVPAGVTEPTARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWYPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWYPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWYPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKASHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRCWPTCKTAHLVPEPAARTLALLADLYDRELVGVISWAKQIPGFTDLQLNDQVRPHTWCPSPRRGRWRFWLTCMIVKLQFNGQFGANLSSPGGLSRGVASKKYLGEPV*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00149446;
90% Identity: iTF_00149446;
80% Identity: iTF_00149446;