Basic Information

Gene Symbol
-
Assembly
GCA_947623375.1
Location
OX392523.1:15018444-15032083[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 40 0.00041 0.037 15.5 3.1 1 23 11 33 11 33 0.98
2 40 0.0007 0.064 14.7 1.5 1 23 40 63 40 63 0.93
3 40 0.00067 0.061 14.8 0.3 2 23 72 94 71 94 0.96
4 40 1.6e-05 0.0015 19.9 0.3 2 23 101 122 101 122 0.98
5 40 0.00039 0.036 15.5 2.0 1 23 128 152 128 152 0.97
6 40 0.0058 0.53 11.8 0.9 1 23 158 180 158 180 0.98
7 40 1.5e-05 0.0014 20.0 1.0 2 23 188 210 187 210 0.97
8 40 0.24 22 6.7 0.0 1 23 217 240 217 240 0.95
9 40 0.24 22 6.7 0.0 1 23 247 270 247 270 0.95
10 40 0.24 22 6.7 0.0 1 23 277 300 277 300 0.95
11 40 0.24 22 6.7 0.0 1 23 307 330 307 330 0.95
12 40 0.24 22 6.7 0.0 1 23 337 360 337 360 0.95
13 40 0.24 22 6.7 0.0 1 23 367 390 367 390 0.95
14 40 0.24 22 6.7 0.0 1 23 397 420 397 420 0.95
15 40 0.24 22 6.7 0.0 1 23 431 454 431 454 0.95
16 40 0.24 22 6.7 0.0 1 23 461 484 461 484 0.95
17 40 0.24 22 6.7 0.0 1 23 491 514 491 514 0.95
18 40 0.24 22 6.7 0.0 1 23 521 544 521 544 0.95
19 40 0.24 22 6.7 0.0 1 23 551 574 551 574 0.95
20 40 0.24 22 6.7 0.0 1 23 581 604 581 604 0.95
21 40 0.24 22 6.7 0.0 1 23 611 634 611 634 0.95
22 40 0.24 22 6.7 0.0 1 23 641 664 641 664 0.95
23 40 0.24 22 6.7 0.0 1 23 671 694 671 694 0.95
24 40 0.24 22 6.7 0.0 1 23 701 724 701 724 0.95
25 40 0.24 22 6.7 0.0 1 23 731 754 731 754 0.95
26 40 0.24 22 6.7 0.0 1 23 761 784 761 784 0.95
27 40 0.24 22 6.7 0.0 1 23 791 814 791 814 0.95
28 40 0.24 22 6.7 0.0 1 23 821 844 821 844 0.95
29 40 0.24 22 6.7 0.0 1 23 851 874 851 874 0.95
30 40 0.24 22 6.7 0.0 1 23 881 904 881 904 0.95
31 40 0.24 22 6.7 0.0 1 23 911 934 911 934 0.95
32 40 0.24 22 6.7 0.0 1 23 941 964 941 964 0.95
33 40 0.24 22 6.7 0.0 1 23 971 994 971 994 0.95
34 40 0.24 22 6.7 0.0 1 23 1001 1024 1001 1024 0.95
35 40 0.24 22 6.7 0.0 1 23 1031 1054 1031 1054 0.95
36 40 0.24 22 6.7 0.0 1 23 1061 1084 1061 1084 0.95
37 40 0.24 22 6.7 0.0 1 23 1091 1114 1091 1114 0.95
38 40 0.0068 0.63 11.6 0.3 2 20 1122 1140 1121 1140 0.93
39 40 6.5 5.9e+02 2.3 3.8 1 20 1361 1380 1361 1383 0.90
40 40 0.16 15 7.3 3.1 1 23 1538 1560 1538 1560 0.98

Sequence Information

Coding Sequence
ATGTTATTCGCTGTTTCAGAATCGAAGCCGTTCAAGTGTTCCTCCTGTCCGTACGCGTGTCGGGACAGCTCGACGCTGCGCAAGCATCAGGCGAGGCATGCGGGCCTGGTCACATATTACCAATGTGGCATGTGCGATACGAGCTGCAAAACCAAGGAGACTCTCAAAGTGCATGTAGCCGAGAAGCATTTTGACGTCGACATGAAGAGGATGGAGTGCGACGCCTGCGGAAAACGGTTCAAATACCGACAACAAATCGTCAACCATATCCGAACCGTCCACGAGAAGTCCACATCGGCCAAATGTGACATTTGTGGGCTCGTCATCAGCAATAAGTACAATCTGCGATACCATATGCGCATACACGTCGACGAGAAACCGTATGTGTGCACGGTGACAGGGTGTGGCAAGAGATACAAACACACCAGTTCCCTCCTGAAGCACACGGTGACGCACTACCCGGCGAAGCAGTTCCCGTGCAGGATCTGCGACAAGCTGTTCAGCCGCGAGAAGCGGATGCTGCTCCATCTCAACACGCACATGGCTAAAGTGAAAAACGTCCAGTGCGACTACTGCGGTGTTTCTTTCTACAATAAAAAGTACTTAACCAACCACATCCAACGGAAGCACGGCAGAAAGAAACAGAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACGTGAGTAGAAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACAAGTACATCTGCGACCTGTGCGGCCTCGTCACCGCCAACAAGCCCAGCATCGTCATGCACCTCAAGTACGGGCACGCCGCCAACAACAACGTACTAATATGCGCCATTTGTCAGAAGACTTTCAAGCGAGACTTCAACCTGCAACTGCACTACTGGGAGGAACACGAGGTCGAATACGACATCCCCAACAGAAAGAAGAAGAAACAAAGGAAAAAGAAAAAAGAGCCAGTAGTCGAAGTGAAACAAGAGATAGAGGAAGGGCCGTGCGAGAATATATATGATGGCGAAGAGTTCTTCGAGGTGTCGCCGAAGGTGGAACCCTTTGATGACGTTGGACTAGAAGAATTTACAAGTATGGCGCCGACGGAAAACCCGAATGCTTTCGTAGAAGTCACCTCGGATATGGTGGACGAGTTCATCAGGCCCGTGCAGAGGAGGGTCGACAACGACAGGAGGAAACATTCCAGGGAGTTTCTTGACAAAAAGTGCGAGGCACAAGTGGTGAAACAGGTCAACGGTTTAATGGAGAAAACGAGACAGAAAATAGCGGCGAGGACACTGGAGCGAACGAGACGGAAATACAATCGGCTGATGCGAAAGGCTATTAAAGTTACTAAAAGAATAGGTAAAACAACCAAAGACAAATTAGGAGATATAGCAGAACATATAGAGGAACAGCAAAACGATAATAAGGAAAAGGATGAAATAACCAGTATAGACAATGAAGTAGATATCGATACAAAAGAAACGTTCATTGCAAATGAAAAAATAGAAACGAAGATGGGTCAAAATAGGAAATTAAAGATCAATACACATCAGTGCTATGTGTGTTTTAAGCTTTATCCAACTAAAGAAGAACTATTGGAACACTGCAAAGATCACTTTGACCTGTGCAACATCAAGACGTTAAAGAAATGTCCTCTTTGCGACTACGCGACTAATCTCAGTGTTACCGTGCACTTGAAGAGAAAACACAACATTCGCGTCAAAGTGCCGTACGGCACCTTCGCTGATGACAAACAAAACGAAGGCTCCAGATATTATTATGAAGTAAACGATGAAAGAATAAAGAAAGTAGAGATTATACCTAGTGTAAAGAATCTTAATAAAAGAGCGAGTAATAAAATTGATAAAAATAATAGAGATAAGAAAAATAAAGGTCTGCTTAAGAGAAAGTTAGTTAAGAAAGGTAATGAATGGATAGTTATGAACGAAAAAATGAAGATTAATGATTATATGTTGCCTCAGTTTGATAAAATAGAAAGTAAAGCTGTTAAAGGTGGGTATTTAGATAGATTGAAAGAACTTTATAAAGTGGCTAAGAAGGAAGGCAAGAAAATGCTCTTCCCTTGTGAGTCTTGTGATAAAGTATGTCAGAGTCTATGTGGTTTGAAGCTCCACGGTAGAAAACATGAAGCTAATCCGAAACCGTTTAAACCTAAAGTTTGGAAACATAAAAATAAAACACCAAATGATGATAAGACGAGTGATGGTCCAAAAAAGAAAAAAGTTACAAACAAAGACAATCGCACGGCGCAACCCAAACCAGTAGTAAACAAGCACAAATGTGATAAAGAATTAATAGACTTCTATGAACGCAATATTAAAGGAAGTGATGTAGAATTTTGGCAGTTCTTGAAAATATACAATAAAATGGGAAGAGAGAATGTCAACGATTTTGATGATTTGCAGAAGAGCACTTCATTTGGACTGCATTGCAATGAAGAATATGAAGATAATGCTCCAAATACTAATGATTTGAGAGTAGAACAGTGCAATAGTGTGGACAATGCTAAGAATTTAGGTGTAAAGCCTACTAAAGTTAGGAAGGCTGCAAAGAATGCATTTACAAGAGTGATTAGATTAAGTAACCGAGAATTGAAGAAGAGGAATGAAGCAAAAAAGAGGCTGAGGCTGAAAATAAAATTAAGTAGCGAAAATATTGAGTAA
Protein Sequence
MLFAVSESKPFKCSSCPYACRDSSTLRKHQARHAGLVTYYQCGMCDTSCKTKETLKVHVAEKHFDVDMKRMECDACGKRFKYRQQIVNHIRTVHEKSTSAKCDICGLVISNKYNLRYHMRIHVDEKPYVCTVTGCGKRYKHTSSLLKHTVTHYPAKQFPCRICDKLFSREKRMLLHLNTHMAKVKNVQCDYCGVSFYNKKYLTNHIQRKHGRKKQKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNVSRNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNKYICDLCGLVTANKPSIVMHLKYGHAANNNVLICAICQKTFKRDFNLQLHYWEEHEVEYDIPNRKKKKQRKKKKEPVVEVKQEIEEGPCENIYDGEEFFEVSPKVEPFDDVGLEEFTSMAPTENPNAFVEVTSDMVDEFIRPVQRRVDNDRRKHSREFLDKKCEAQVVKQVNGLMEKTRQKIAARTLERTRRKYNRLMRKAIKVTKRIGKTTKDKLGDIAEHIEEQQNDNKEKDEITSIDNEVDIDTKETFIANEKIETKMGQNRKLKINTHQCYVCFKLYPTKEELLEHCKDHFDLCNIKTLKKCPLCDYATNLSVTVHLKRKHNIRVKVPYGTFADDKQNEGSRYYYEVNDERIKKVEIIPSVKNLNKRASNKIDKNNRDKKNKGLLKRKLVKKGNEWIVMNEKMKINDYMLPQFDKIESKAVKGGYLDRLKELYKVAKKEGKKMLFPCESCDKVCQSLCGLKLHGRKHEANPKPFKPKVWKHKNKTPNDDKTSDGPKKKKVTNKDNRTAQPKPVVNKHKCDKELIDFYERNIKGSDVEFWQFLKIYNKMGRENVNDFDDLQKSTSFGLHCNEEYEDNAPNTNDLRVEQCNSVDNAKNLGVKPTKVRKAAKNAFTRVIRLSNRELKKRNEAKKRLRLKIKLSSENIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-