Basic Information

Insect: Aporophyla nigra
Gene Symbol: THAP3
Assembly: GCA_947507805.1
Location: OX382319.1:5892541-5921620[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.61 52 5.2 0.7 1 23 354 376 354 376 0.83

2 11 0.0029 0.25 12.5 1.3 1 23 383 406 383 406 0.93

3 11 0.3 25 6.2 0.2 1 23 410 432 410 432 0.92

4 11 0.19 16 6.8 0.8 1 23 437 460 437 460 0.96

5 11 0.0031 0.27 12.4 0.3 1 23 464 487 464 487 0.96

6 11 1.2 1e+02 4.3 0.2 2 21 531 550 531 551 0.89

7 11 1.5 1.2e+02 4.0 0.2 3 23 605 626 603 626 0.94

8 11 0.0043 0.36 12.0 0.6 2 20 642 660 641 663 0.92

9 11 2.3e-05 0.0019 19.2 2.9 1 23 669 691 669 691 0.99

10 11 0.00025 0.021 15.9 2.8 1 23 698 720 698 720 0.98

11 11 0.0035 0.29 12.3 4.0 1 23 726 749 726 749 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.61	52	5.2	0.7	1	23	354	376	354	376	0.83
2	11	0.0029	0.25	12.5	1.3	1	23	383	406	383	406	0.93
3	11	0.3	25	6.2	0.2	1	23	410	432	410	432	0.92
4	11	0.19	16	6.8	0.8	1	23	437	460	437	460	0.96
5	11	0.0031	0.27	12.4	0.3	1	23	464	487	464	487	0.96
6	11	1.2	1e+02	4.3	0.2	2	21	531	550	531	551	0.89
7	11	1.5	1.2e+02	4.0	0.2	3	23	605	626	603	626	0.94
8	11	0.0043	0.36	12.0	0.6	2	20	642	660	641	663	0.92
9	11	2.3e-05	0.0019	19.2	2.9	1	23	669	691	669	691	0.99
10	11	0.00025	0.021	15.9	2.8	1	23	698	720	698	720	0.98
11	11	0.0035	0.29	12.3	4.0	1	23	726	749	726	749	0.89

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTATGAGTTGTACTAATGACACGAGAACAAGTAACAAAAGCCATGGAATCACATTTCACTTGTTCCCAAAGCAGCCGGAGCTCCGCGCTGCCTGGGTGGAGGCTCTCGGCGAAACTGACTGGGAGCCCAAGGAAAGAAGCACCGTGTGCTCCGAGCACTTCAGGAGTGATGATATCTATGAGACCAAAGGTGGGCTTAGGAAGATTAAATGCGGAGCAGTGCCTGTTGTGATGACACACTCAGCAGACGACCTTGACGCACCAGCCGCTTTGAGGGTGTGCCGAATATGCCTGGTGATGGACAGCAAGATGTATCACATAAAAGAATTCAAGCTGGATCAAATGTATGAGCAAATAACTGGATTGGCTACTTCAGAAGAGCGTCTACCGCAGCGTGTGTGCTGGGAATGCGCCGCTCGTCTGAACTCGGCGTGTCGCTTCAGAAACAAAGCTTTGCGCTGCGATGCCTTGCTGCACGATCTTCTGGAGCCAGACTCTTATCTAAAAGTCCGCGACGTTAGATCGGTCAACAGAAAGCATAACCAACTCACTTCTAACTTAGTACATCAATTATACGAAAATAATGACTTCGATTTGAGCGTCAAAGATGTCTCCAACGTCAAAGGCGAAGAAATACTGAATACTCCCGAAATTATAAGCGAAGAAATTGACGTGAACAGCCTAGCACCTATAAATGAAGTAGAAATTAAAGACGAAAGTAGTAATGAGATTTTCTTTGAAGAATATGACCATTTTGATGATGACGATGATAAGGCGTTAAGTGAAGTTTATGTCGCGAAGAAAGAGAAGGCCAAAGTTAAGAAGAAGAGGGAGAGAGTTGTGAAGAAAGTTAAGGCGCCGAAGAAGGTTGAAGAAGATGAGGATCCGGACACTACTAGGGATAAGTACAAAACAAACGACGTGAAGCGCCGTCGAAACAACGAAGCGTTCGACGAAGCGCTGTTCACGATCACTCCTCTAACTTACGACCAACAAATAGCGGAGATATTGAAACGTCAAGAAAGTTACAACTACGTCAGCGCCCCCTATAAGTGTACGATATGCTACCGAGGGTTCCAAATCCGGGATCGGTATGTCGCTCATTCTGTGAGGCATACTGAGAAAAGCGGTGCATTTGAATGTTTTATCTGTAAAACTAGACTGAAAACTAGTCGCGCGCTACGGAAACATCTAACGGCGCAACATACGGAGCAATATAGCTGTAAGGGATGTCCGTTCGTCACTAGAAATAGAGGTGTAGCGAGGGAACATGAAAAATGGCATGGAGGAACGAAATACCAGTGTCCACATTGTGCTAGTGAGTTTGATAAAATAACAACTTATTTGGGACATATTCGAATAAAACACGTTTCGGATTTCGTATGTGAACTGTGTGGGTATACATTCGTCAGTGAGAAAGGAATTGCTGTTCATAAGAAGAAAAAACATCGGATTGATAAAGCGATGAAGAATCAAAGTTGTGACCATATGACCTTCTTCAAGTCAACAATACGGTACCCTACCAAACCTGAGAAGTTGTCACTTGATGTTCTTTCCACATTGACATTAGAAGGGCCTTACTGTGAGCAATGTGACGTGAAGTTCGTGTCGGAAGAGGCTCACGAGAGACATCTGAAGTTATCTGCGAAACACAGCAGTGATCACGACCCCAACCGAATCCGCAACGACTCACAGAGCATGAATACAGAGCGCAGCGGTCGCGTCATGAGGCGTATAGAGAGGAGGCCGCTCATACACCCGCGCCTACCTAGCGACGACCAGGACGAGCCGCCCGTCAACTGCGAACAGTGCGGGCTACAACTTCGGGACCTGCGAGTGTACGCGCAACACTTTCGTCGGGCTCACCCGGATAAGAACAGAACTAAGTACCCTGCGATGAAGACTCCGTGCATGTGTGAGCAGTGCGGCAAGATATTCCAGAGCATGGCCCTCTTAAAAGACCATATGTGGGTTCATACCGGTGAAAAACGGTTTAAATGTGACCGCTGCACCAAGAGCTTCACCCAGAAGACGAACCTAGCGTTCCATATGAGGGTCCACAGCTCTTCACGACCCTCATACGAGTGTCCGCTGTGCGGGAAACACTTCGCGTTCTTCAATAACAGAAGACGACATATGTTTATCCACACCGGCCTGAAACCCTTCAAATGTGACACATGTGGGAAATGCTTCACTACGGCAGGCGAACACAGGGCGCATGTTGAACATGTACATCTCAAGAAACCATGGCCCAAGCGAGCTAGGCAGAGAAACAGGGATTGGAAGTGCGATGACCCCAGTATCGAGGACTGA
Protein Sequence: MRCSVMSCTNDTRTSNKSHGITFHLFPKQPELRAAWVEALGETDWEPKERSTVCSEHFRSDDIYETKGGLRKIKCGAVPVVMTHSADDLDAPAALRVCRICLVMDSKMYHIKEFKLDQMYEQITGLATSEERLPQRVCWECAARLNSACRFRNKALRCDALLHDLLEPDSYLKVRDVRSVNRKHNQLTSNLVHQLYENNDFDLSVKDVSNVKGEEILNTPEIISEEIDVNSLAPINEVEIKDESSNEIFFEEYDHFDDDDDKALSEVYVAKKEKAKVKKKRERVVKKVKAPKKVEEDEDPDTTRDKYKTNDVKRRRNNEAFDEALFTITPLTYDQQIAEILKRQESYNYVSAPYKCTICYRGFQIRDRYVAHSVRHTEKSGAFECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHGGTKYQCPHCASEFDKITTYLGHIRIKHVSDFVCELCGYTFVSEKGIAVHKKKKHRIDKAMKNQSCDHMTFFKSTIRYPTKPEKLSLDVLSTLTLEGPYCEQCDVKFVSEEAHERHLKLSAKHSSDHDPNRIRNDSQSMNTERSGRVMRRIERRPLIHPRLPSDDQDEPPVNCEQCGLQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLAFHMRVHSSSRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTAGEHRAHVEHVHLKKPWPKRARQRNRDWKCDDPSIED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01441464;
90% Identity: iTF_00147525;
80% Identity: iTF_00147525;