Basic Information

Insect: Aporophyla nigra
Gene Symbol: ZNF219
Assembly: GCA_947507805.1
Location: OX382299.1:24453169-24482968[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0015 0.13 13.4 3.0 1 23 395 418 395 418 0.96

2 7 0.00085 0.072 14.2 3.3 1 23 570 592 570 592 0.98

3 7 7.1e-05 0.006 17.6 0.8 1 23 597 619 597 619 0.98

4 7 4.9e-06 0.00042 21.2 0.5 1 23 625 648 625 648 0.93

5 7 3.9e-07 3.3e-05 24.7 1.4 1 23 654 676 654 676 0.99

6 7 1.4e-05 0.0012 19.8 3.3 1 23 682 704 682 704 0.99

7 7 3.4e-05 0.0029 18.6 1.9 1 23 710 732 710 732 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0015	0.13	13.4	3.0	1	23	395	418	395	418	0.96
2	7	0.00085	0.072	14.2	3.3	1	23	570	592	570	592	0.98
3	7	7.1e-05	0.006	17.6	0.8	1	23	597	619	597	619	0.98
4	7	4.9e-06	0.00042	21.2	0.5	1	23	625	648	625	648	0.93
5	7	3.9e-07	3.3e-05	24.7	1.4	1	23	654	676	654	676	0.99
6	7	1.4e-05	0.0012	19.8	3.3	1	23	682	704	682	704	0.99
7	7	3.4e-05	0.0029	18.6	1.9	1	23	710	732	710	732	0.97

Sequence Information

Coding Sequence: ATGGATGATGAAACCGTCACGCACTATATAACTTCCCACCCAGCTGATCAGACAGTTCATGTAGATGGCAATGCCCTGGCCCTCAATGTGCAGGATGATGGAGGCGGCAGGGTGGCCATCATGCATTCACAGACCTACTCTACATCACTATGCAGGCAAGTGGCAGTGGGTGACCATGTGGTGGAAGGACAATGGAGTGATGAGATCATGGACCCAGAAGGCAGGCTGGCAGCACTTATGGCCCACATCACGGCCCAACAGTCCAGAGGGCAACAACAACTGCACCATAAGGTCCATACAGTGAGGGGTGATGTGGACACATCTATTATACTTGATAGTTCCATGAGACTCTTCCATGGGCAGCCAATGGACCAGTCACAGGAACCGATAGTGGTGGAGGTACCGCGCCTGCCGCCGCTCCCTCCCCTGCAGGAGATGAAGCGGTGTCAGGAAAGTGACTGGTTCAATAAGAATAAATCAACACTCAAAGATGATTCTTCAATGATTGATTCTGACGGGCCGGTGTTAGACCTCGGCCCTGGGGCGTCGCCGGGGCAGCACAAACTGCAAAGCAAGAAGAGTCTTCCACACAAGAAAAGGATATCTAGGAAGCTAAAAAAGAATAATGGGAATTGTACTCCTCAGCAGGACATAGTGGTGATCAGTTGCACAGACGTCGAAGGTCGCATCAGCTGCGCGGACCACGGACAGGAGCAGGAGATCCTGCCGGATAACTTTGTGCAGCAGGAGCACATGCCAGTCGAGTCGCATCATATTACACATGAGGTCCGTCCGATCCTGCTCTGCCAGCTGTGCGGCGAGTTCTACGGCGAGGAGCAGCTGAAGTTCTACCAGCACTTGAAGCAGCACTACGAGCCGCACATCATCATCGAGAACCCCGTGCAAGACCTGGGAATGGATAAGATGACCAACTCGTGCATCGTAGATAACGTTGCAACAATTCCCGACTCGATAGTAGAACTATCTTTAGAAAATTCCATACCAAAAACTATATACCAATCAATGGACAAACACGTTTTATACACGACAAGCGATAAAACGTTCACGTACGCTAACAATAAGCTTCAGTATTCTATGGCAAGTATGGACAAGGAACCGCCGACGGTCGTTCAAGAGGCTGAGAAGGCGGATCTGTACGATAGTCTGGATAAGCTGGATTTGTATAGCTGTGGGAAGTGTAACAAGTCGTTCAGGAAGCAGAAGCAATGTGAAGCGCATATAAAGGAGGCGCATTCTAATATGAAGTTGGAAGACATGGGCGAGTTCAGCGAGCCTGAGGACCTGATGGAGGGCATCCACGTGGCAGTGGACGAGCCCCCAGAGCACTACGAGCACACGCTGCTGCCGCACCTCACGGTGGAGAACGGGCATGCGCACCAGGACAACGTGAGGCACTGGTACGGGCGCGGCGCGGGCGGCGCGGCGGGCGGCGCGGCGTGCTGTGTGGCGTGCGCGGGAACGCCGCACGACTCGCACCACCTCAAGCTGCTTAAAGACGAAGTCCTCCGACGAATCTTAGAGACAGACGTAGCGACTGACAACCAGAACTTCACGGACAGCACGATGACCGACACCGCCGACACCGCCGACACGGCCGACACGGCCGACGCTCCCGACACAGCCGACCTGCCGCCCGACGAGCCTCCGCCCAACGACAAGTCGGACGATAAGAAGAAACAGAAGCGGTTCGAATGCCAGCAGTGCCAGCGAGTGTTCCAGCACAGGAACAGTCTCCTGTACCACATGCTGTCGCACAGCGGCAAGCAGCATACGTGTCGCGAGTGCGGGAAGGGCTTCTACACCGTCGCCGCGCTCAAGATCCACAAGCGCGTGCACAACGGAGACCGGCCCTACAAGTGCGACGTGTGCGGGCGAGACTTCCGCCAGTGGAGCGACCTCAAGTACCACAAGGTGTCCATACACTCCGACGAGAAAATGTTCAAATGCGAGTTCTGCGGCAAGGAGTTTGCGCGCAAGTACTCGCTGAACGTACACCGGCGCATCCACACGGGCGAGCGGAACTACAAGTGTGACTACTGTAACAAGACCTTCCGCGCCTCCTCCTACCGCCTCAGCCACATGCGGACCCACACCGGCGACCGGCCGCACAAGTGCGCGCAGTGCGACAAGTGCTTCCGCGTGGCCGGCGACCTGCGGCGCCACGCGCTCGTGCACGACAAGCTGCGCGCGCGCCACGCGCACAAGCACAAGCGCGCCGACACCGGCGACAAGCCCGCCAAGCCGGACGACAAACAACACCACAACATCAAAATCGAAGACACCGCACTTTCCAAAAACATTAAAAAGGTCGCCCTCGCTTCCACCACCAAATCACCCAACATTCTCAGAACTGCTCTCACGACTGATAAGAAAAAACCTGCTAAAAAGAACCAGAGCTTAAAAAAAGGGGCACCCAACGTTACCTTAGACCAACTAGACAACAGCTACACCAACAATGTAGAGGTATTCGACACGCGGCAGGATAACTATGGCAAACTGAACGTAGTGTCCATCAAAGAGATATACAACAACCCCGATTACAAGCAGGAATTAGATGACACATTCACTAAACAAATTATAGGTCAATACAAAGACGAAGAGACGCAGGAGAGAGAGCTCGCGACTCTTAGACCGATTTTCAGGAACAACGTGCTGTGTGACACTGTGCAGCCCGACCCGGCTGTGTTCAGGTCTGAGAACACTGACGGTAAGATGCAAGTGTACACACACATAGAGAAGAACAACACTATAGTTCCTAATTCCCAAGTTTCACTCAACGATATGCGGCACTTGGAGCGCGAGGTGAGGAGCGACGTACACGGAGAAACCACTGAAAATGGTTTCATAGAAAGACTTACAGCGTTATACAATATACCCGCTGTATGA
Protein Sequence: MDDETVTHYITSHPADQTVHVDGNALALNVQDDGGGRVAIMHSQTYSTSLCRQVAVGDHVVEGQWSDEIMDPEGRLAALMAHITAQQSRGQQQLHHKVHTVRGDVDTSIILDSSMRLFHGQPMDQSQEPIVVEVPRLPPLPPLQEMKRCQESDWFNKNKSTLKDDSSMIDSDGPVLDLGPGASPGQHKLQSKKSLPHKKRISRKLKKNNGNCTPQQDIVVISCTDVEGRISCADHGQEQEILPDNFVQQEHMPVESHHITHEVRPILLCQLCGEFYGEEQLKFYQHLKQHYEPHIIIENPVQDLGMDKMTNSCIVDNVATIPDSIVELSLENSIPKTIYQSMDKHVLYTTSDKTFTYANNKLQYSMASMDKEPPTVVQEAEKADLYDSLDKLDLYSCGKCNKSFRKQKQCEAHIKEAHSNMKLEDMGEFSEPEDLMEGIHVAVDEPPEHYEHTLLPHLTVENGHAHQDNVRHWYGRGAGGAAGGAACCVACAGTPHDSHHLKLLKDEVLRRILETDVATDNQNFTDSTMTDTADTADTADTADAPDTADLPPDEPPPNDKSDDKKKQKRFECQQCQRVFQHRNSLLYHMLSHSGKQHTCRECGKGFYTVAALKIHKRVHNGDRPYKCDVCGRDFRQWSDLKYHKVSIHSDEKMFKCEFCGKEFARKYSLNVHRRIHTGERNYKCDYCNKTFRASSYRLSHMRTHTGDRPHKCAQCDKCFRVAGDLRRHALVHDKLRARHAHKHKRADTGDKPAKPDDKQHHNIKIEDTALSKNIKKVALASTTKSPNILRTALTTDKKKPAKKNQSLKKGAPNVTLDQLDNSYTNNVEVFDTRQDNYGKLNVVSIKEIYNNPDYKQELDDTFTKQIIGQYKDEETQERELATLRPIFRNNVLCDTVQPDPAVFRSENTDGKMQVYTHIEKNNTIVPNSQVSLNDMRHLEREVRSDVHGETTENGFIERLTALYNIPAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00908231;
90% Identity: -
80% Identity: -